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Full-Text Articles in Biomedical
Optimization Of Bioprinting Process Using Design Of Experiments (Doe) And Taguchi Method, Maria Veronica Gonzalez
Optimization Of Bioprinting Process Using Design Of Experiments (Doe) And Taguchi Method, Maria Veronica Gonzalez
Open Access Theses & Dissertations
At this time there is a need for new fabrication techniques for engineering complex biological structures related to regenerative medicine, in vitro tissue analysis, and pharmaceutical testing with the purpose of placing specific cells in specific target locations. Right now, there is no enough conventional cell seeding methods that can achieve it. In order to achieve it, bio-fabrication, which is a delivery mechanism capable of placing biomaterials, cells, and bioactive macromolecules in specific target locations, comes to play an important role in this area. Among different approaches, bioprinting is one of the most useful processes that use drop-on-demand delivery mechanisms …
Characterizing Hypoxia And Its Behavioral Effects In 3-Dimensional Cell Aggregates, Matthew Lorincz Skiles
Characterizing Hypoxia And Its Behavioral Effects In 3-Dimensional Cell Aggregates, Matthew Lorincz Skiles
Theses and Dissertations
Cell transplantation can be considered a regenerative therapy, an intervention which attempts to replace or restore the function of compromised tissue by harnessing innate properties of cells that cannot be replicated artificially. For such therapies to succeed, it will be necessary to understand and closely match the physiological conditions that govern cell behaviors in vivo. One important factor is low oxygen tension, termed hypoxia, which is often overlooked in vitro. Because oxygen insufficiency can lead to cell death, hypoxia has traditionally been viewed as a negative condition. However, hypoxia can also serve as a potent regulator of crucial cell behaviors …