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Full-Text Articles in Biomedical

Recruitment Of The Intracellular Ca2+ By Ultrashort Electric Stimuli: The Impact Of Pulse Duration, Iurii Semenov, Shu Xiao, Olga N. Pakhomova, Andrei G. Pakhomov Jan 2013

Recruitment Of The Intracellular Ca2+ By Ultrashort Electric Stimuli: The Impact Of Pulse Duration, Iurii Semenov, Shu Xiao, Olga N. Pakhomova, Andrei G. Pakhomov

Bioelectrics Publications

Nanosecond-duration electric stimuli are distinguished by the ability to permeabilize intracellular membranes and recruit Ca2+ from intracellular stores. We quantified this effect in non-excitable cells (CHO) using ratiometric Ca2+ imaging with Fura-2. In a Ca2+-free medium, 10-, 60-, and 300-ns stimuli evoked Ca2+ transients by mobilization of Ca2+ from the endoplasmic reticulum. With 2 mM external Ca2+, the transients included both extra- and intracellular components. The recruitment of intracellular Ca2+ increased as the stimulus duration decreased. At the threshold of 200–300 nM, the transients were amplified by calcium-induced calcium release. We …


Tpm: Cloud-Based Tele Ptsd Monitor Using Multi-Dimensional Information, Roger Xu, Gang Mei, Guangfan Zhang, Pan Gao, Aaron Pepe, Jiang Li, James D. Westwood (Ed.), Susan W. Westwood (Ed.), Li Felländer-Tsai (Ed.), Randy S. Haluck (Ed.), Richard A. Robb (Ed.), Steven Senger (Ed.), Kirby G. Vosburgh (Ed.) Jan 2013

Tpm: Cloud-Based Tele Ptsd Monitor Using Multi-Dimensional Information, Roger Xu, Gang Mei, Guangfan Zhang, Pan Gao, Aaron Pepe, Jiang Li, James D. Westwood (Ed.), Susan W. Westwood (Ed.), Li Felländer-Tsai (Ed.), Randy S. Haluck (Ed.), Richard A. Robb (Ed.), Steven Senger (Ed.), Kirby G. Vosburgh (Ed.)

Electrical & Computer Engineering Faculty Publications

An automated system that can remotely and non-intrusively screen individuals at high risk for Post-Traumatic Stress Disorder (PTSD) and monitor their progress during treatment would be desired by many Veterans Affairs (VAs) as well as other PTSD treatment and research organizations. In this paper, we present an automated, cloud-based Tele-PTSD Monitor (TPM) system based on the fusion of multiple sources of information. The TPM system can be hosted in a cloud environment and accessed through landline or cell phones, or on the Internet through a web portal or mobile application (app).