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Role Of Mammary Microenvironment In Promoting Left-Right Differences In Tumor Progression, Metastasis, And Therapeutic Response, Huda Issa Atiya

Theses and Dissertations

Metastasis is the main cause of death in breast cancer patients; however, there are currently no treatments available to treat or prevent metastasis. This is in part because regulators of metastasis are not yet fully understood. Over the past century researchers began to study metastasis regulators by different hypotheses, such as the seed and soil hypothesis which focuses on studying the role of cancer cells, the seeds, and the tissue microenvironment, the soil, in regulating metastasis. Although lots of studies have focused on the microenvironment of metastatic sites and their roles in regulating metastasis, limited studies have focused on the …