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Full-Text Articles in Biomedical
Technobiology Paradigm In Nanomedicine: Treating Cancer With Magnetoelectric Nanoparticles, Emmanuel Stimphil
Technobiology Paradigm In Nanomedicine: Treating Cancer With Magnetoelectric Nanoparticles, Emmanuel Stimphil
FIU Electronic Theses and Dissertations
Today, cancer is the world’s deadliest disease. Despite significant progress to find a cure, especially over the last decade, with immunotherapy rapidly becoming the state of the art, major open questions remain. Each successful therapy is not only limited to a few cancers but also has relatively low specificity to target cancer cells; although cancer cells can indeed be eradicated, many normal cells are sacrificed as collateral damage. To fill this gap, we have developed a class of multiferroic nanostructures known as magnetoelectric nanoparticles (MENs) that can be used to enable externally controlled high-specificity targeted delivery and release of therapeutic …
Bionano Electronics: Magneto-Electric Nanoparticles For Drug Delivery, Brain Stimulation And Imaging Applications, Rakesh Guduru
Bionano Electronics: Magneto-Electric Nanoparticles For Drug Delivery, Brain Stimulation And Imaging Applications, Rakesh Guduru
FIU Electronic Theses and Dissertations
Nanoparticles are often considered as efficient drug delivery vehicles for precisely dispensing the therapeutic payloads specifically to the diseased sites in the patient’s body, thereby minimizing the toxic side effects of the payloads on the healthy tissue. However, the fundamental physics that underlies the nanoparticles’ intrinsic interaction with the surrounding cells is inadequately elucidated. The ability of the nanoparticles to precisely control the release of its payloads externally (on-demand) without depending on the physiological conditions of the target sites has the potential to enable patient- and disease-specific nanomedicine, also known as Personalized NanoMedicine (PNM). In this dissertation, magneto-electric nanoparticles (MENs) …