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Thin Film Based Biosensors For Point Of Care Diagnosis Of Cortisol, Syed Khalid Pasha
Thin Film Based Biosensors For Point Of Care Diagnosis Of Cortisol, Syed Khalid Pasha
FIU Electronic Theses and Dissertations
This dissertation explores the different ways to create thin film-based biosensors that are capable of rapid and label-free detection of cortisol, a non-specific biomarker closely linked to stress, within the physiological range of 10pM to 10 uM. Increased cortisol levels have been linked to stress-related diseases, such as chronic fatigue syndrome, irritable bowel syndrome, and post-traumatic stress disorder. It also plays a role in the suppression of the immune system as well. Therefore, accurate measurement of cortisol in saliva, serum, plasma, urine, sweat, and hair, is clinically significance to predict physical and mental diseases.
In this dissertation, thin film-based electrochemical …