Open Access. Powered by Scholars. Published by Universities.®
- Keyword
- Publication
- Publication Type
Articles 1 - 2 of 2
Full-Text Articles in Biomedical
The Effects Of Vagus Nerve Stimulation On Neuroinflammation In Epilepsy, Elizabeth A. St. Clair, Gabriel O Albors, Pedro Irazoqui Dr., Amy Brewster
The Effects Of Vagus Nerve Stimulation On Neuroinflammation In Epilepsy, Elizabeth A. St. Clair, Gabriel O Albors, Pedro Irazoqui Dr., Amy Brewster
The Summer Undergraduate Research Fellowship (SURF) Symposium
Epilepsy is a neurological disorder characterized by chronic, unexplainable seizures. Recurring epileptic seizures are associated with long-term structural damage and cognitive deficits, and can even lead to sudden, unexplainable death. Approximately 30% of epilepsy cases are not responsive to medication. Epileptic seizures often induce inflammation in the brain and may increase the frequency of future seizures, resulting in a detrimental cycle. Vagus nerve stimulation (VNS) is a non-pharmaceutical treatment method for epilepsy that has been shown to reduce inflammation in peripheral pathways. The role of VNS in the modulation of neuroinflammation has yet to be demonstrated experimentally. To explore this, …
Electronic Desalting For Controlling The Ionic Environment In Droplet-Based Biosensing Platforms, Vikhram Vilasur Swaminathan, Piyush Dak, Bobby Reddy Jr, Eric Salm, Carlos Duarte-Guevara, Yu Zhong, Andrew Fischer, Yi-Shao Liu, Rashid Bashir
Electronic Desalting For Controlling The Ionic Environment In Droplet-Based Biosensing Platforms, Vikhram Vilasur Swaminathan, Piyush Dak, Bobby Reddy Jr, Eric Salm, Carlos Duarte-Guevara, Yu Zhong, Andrew Fischer, Yi-Shao Liu, Rashid Bashir
Birck and NCN Publications
The ability to control the ionic environment in saline waters and aqueous electrolytes is useful for desalination as well as electronic biosensing. We demonstrate a method of electronic desalting at micro-scale through on-chip micro electrodes. We show that, while desalting is limited in bulk solutions with unlimited availability of salts, significant desalting of ≥1 mM solutions can be achieved in sub-nanoliter volume droplets with diameters of ∼250 μm. Within these droplets, by using platinum-black microelectrodes and electrochemical surface treatments, we can enhance the electrode surface area to achieve >99% and 41% salt removal in 1 mM and 10 mM salt …