Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Computer aided diagnosis (2)
- Computerized tomography (2)
- Database systems (2)
- T cells (2)
- Algorithms (1)
-
- Biofluorescence (1)
- Biomolecules (1)
- CTCCAD polyp detection (1)
- Calcium in the body (1)
- Classifier committee (1)
- Classifiers (1)
- Computer aided detection (1)
- Computer-aided detection (1)
- Electric fields (1)
- Electromagnetic fields (1)
- Golgi apparatus (1)
- Medical imaging (1)
- Neural network (1)
- Neural networks (1)
- Patient treatment (1)
- Pattern recognition (1)
- Sensitivity analysis (1)
- Statistical methods (1)
- Support vector machine (1)
- Vectors (1)
- Virtual colonoscopy (1)
- Virtual reality (1)
- Wavelet (1)
- Wavelet transforms (1)
- Publication
- Publication Type
Articles 1 - 4 of 4
Full-Text Articles in Biomedical
The Effects Of Ultrashort Pulsed Electric Fields On The Fluorescent Molecule Bodipy Fl C5 Ceramide, Rachael Sara Shevin
The Effects Of Ultrashort Pulsed Electric Fields On The Fluorescent Molecule Bodipy Fl C5 Ceramide, Rachael Sara Shevin
Electrical & Computer Engineering Theses & Dissertations
Nanosecond pulsed electric fields are able to manipulate internal cell organelles by taking advantage of the small but finite time required for charge to establish across a capacitive barrier. Pulsed electric fields also affect macromolecular structures such as enzymes and proteins. Application of a single nanosecond pulsed electric field decreases the fluorescence of a commercially available biological dye Bodipy FL C5 Ceramide, used to observe the Golgi apparatus of living cells. The effect is seen when the fluorophore is exposed to an electric field both in vitro and when incorporated into the Golgi of a living Jurkat cell. Observation …
Temporal Calcium Response Of Jurkat Cells To Nanosecond Pulsed Electric Fields, Shaka Shakar Scarlett
Temporal Calcium Response Of Jurkat Cells To Nanosecond Pulsed Electric Fields, Shaka Shakar Scarlett
Electrical & Computer Engineering Theses & Dissertations
Nanosecond pulsed electric fields (nsPEF) of megavolt per meter field strengths can interact with subcellular structures [1] and consequently trigger a variety of biological events. The exposure can induce apoptosis, as well as an array of differential "sub-lethal effects." One of the most sensitive and immediate responses is the increase in intracellular calcium concentration in pulsed cells [2], [3][4].We investigated the response of Jurkat cells (a human leukemic cell line) to nsPEFs of 60 ns duration and field strengths from 25 tol00 kV/cm. The development of the induced calcium response in individual cells was studied by spinning-disc confocal microscopy with …
Wavelet Analysis In Virtual Colonoscopy, Sharon Greenblum, Jiang Li, Adam Huang, Ronald M. Summers, Armando Manduca (Ed.), Amir A. Amini (Ed.)
Wavelet Analysis In Virtual Colonoscopy, Sharon Greenblum, Jiang Li, Adam Huang, Ronald M. Summers, Armando Manduca (Ed.), Amir A. Amini (Ed.)
Electrical & Computer Engineering Faculty Publications
The computed tomographic colonography (CTC) computer aided detection (CAD) program is a new method in development to detect colon polyps in virtual colonoscopy. While high sensitivity is consistently achieved, additional features are desired to increase specificity. In this paper, a wavelet analysis was applied to CTCCAD outputs in an attempt to filter out false positive detections. 52 CTCCAD detection images were obtained using a screen capture application. 26 of these images were real polyps, confirmed by optical colonoscopy and 26 were false positive detections. A discrete wavelet transform of each image was computed with the MATLAB wavelet toolbox using the …
Hybrid Committee Classifier For A Computerized Colonic Polyp Detection System, Jiang Li, Jianhua Yao, Nicholas Petrick, Ronald M. Summers, Amy K. Hara, Joseph M. Reinhardt (Ed.), Josien P.W. Pluim (Ed.)
Hybrid Committee Classifier For A Computerized Colonic Polyp Detection System, Jiang Li, Jianhua Yao, Nicholas Petrick, Ronald M. Summers, Amy K. Hara, Joseph M. Reinhardt (Ed.), Josien P.W. Pluim (Ed.)
Electrical & Computer Engineering Faculty Publications
We present a hybrid committee classifier for computer-aided detection (CAD) of colonic polyps in CT colonography (CTC). The classifier involved an ensemble of support vector machines (SVM) and neural networks (NN) for classification, a progressive search algorithm for selecting a set of features used by the SVMs and a floating search algorithm for selecting features used by the NNs. A total of 102 quantitative features were calculated for each polyp candidate found by a prototype CAD system. 3 features were selected for each of 7 SVM classifiers which were then combined to form a committee of SVMs classifier. Similarly, features …