Other Computer Engineering Commons^™

Generative Ai Of Breast Cancer Progression In Gene Expression Space, Xusheng Ai

All Dissertations

Breast cancer is one of the most common and deadly cancers in the world. Although doctors can use gene activity data to better understand different types of breast cancer, it is still difficult to identify the most important genes and to track how the disease changes over time. This is partly because gene data are very large and complex.

This dissertation develops a computer-based framework to study breast cancer using gene expression data. The work focuses on three goals: creating realistic synthetic gene data, identifying important genes linked to cancer, and modeling how breast cancer changes from normal tissue to …

Multiple View Neural Regression Of A Facial Shape Model, Xiang Li

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Creating re-topologized 3D facial meshes is a critical step in high-quality facial animation pipelines, yet it remains a labor-intensive and time-consuming task. Traditional approaches typically rely on multiview stereo reconstruction and specialized photometric environments to acquire accurate geometric and reflectance data under controlled conditions. This dissertation presents work toward more efficient capture of production-ready meshes including (1) developmental aspects of VarIS, a custom-designed light sphere capable of capturing high-resolution stereo geometry and reflectance maps—including diffuse, specular, and normal components under programmable illumination; (2) a study of the effects of camera parameters on automatic 2D and 3D landmarking methods, (3) methods …

Effects Of Lossy Compression Data On Machine Learning Models, Max H. Faykus Iii

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Machine learning is a fundamental tool that is incorporated in every field across academia and other industries. Due to the large amount of data needed for training machine learning models, lossy compression plays a crucial role in storing data. Machine learning involves the use of algorithms and models to learn patterns in data. This allows the AI to make decisions without specific programming. On the other hand, compression utilizes encoding and decoding techniques to reduce the size of files. Compression is either lossy or lossless, lossy causes a loss of data while lossless preserves the data. This dissertation will explore …

A System And Method For Measuring Spatially Varying Surface Appearances With A Study Of Feathers, Jessica Baron-Lis

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Real-world materials, particularly biological structures such as feathers exhibit complex appearances that vary spatially across their surfaces. The field of computer graphics provides a means of understanding such surfaces through material modeling which uses both analytical models and data acquired from light-surface interactions. There are many efforts within the past decade in measuring materials for graphics, but common limitations in these works include not accounting for spatially varying properties and reliance on neural networks and synthetic datasets.

Feathers from modern birds present diverse appearances due to how light interacts with their unique hierarchical microstructures. Variations in those structures lead to …

Advancing Visual Geometric Perception: Camera-Based Depth, Reconstruction, And Active Vision, Ziyue Feng

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The advancement of autonomous driving technology and intelligent robotic applications has emerged as a focal point in the realm of autonomy. One of the driving forces behind this trend is the profound understanding of the environment, and at the core of this endeavor lies the three-dimensional geometric perception. This dissertation embarks on a comprehensive exploration of this domain, emphasizing the advances of depth prediction, 3D scene reconstruction, and active vision to enhance geometric perception and scene understanding capabilities in autonomous driving, embodied AI, and robotics. In the domain of depth prediction, this research addresses the challenges of accurately inferring three-dimensional …

Design And Application Of Smart Systems To Address Analytical Problems, Lucas B. Ayres

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This dissertation is a multidisciplinary effort that integrates low-cost analytical instrumentation, redox chemistry, and artificial intelligence to overcome existing limitations in the fields of wearable sensing technology, Deep Eutectic Solvents (DES), and antioxidant chemistry. The overall goal behind each implemented strategy is to enhance the accuracy, efficiency, and accessibility of analytical processes and technologies. A general overview of the thesis, along with the research outcomes is included in Chapter One. The theoretical framework of this dissertation is presented in Chapter Two. Chapter Three describes the development of a wearable platform (sensor and instrumentation) to rapidly detect (~20 minutes) S. aureus …

Towards Enabling Usable Batteryless Wearables, Arwa Alsubhi

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Wearable devices have become ubiquitous in modern technology, providing a convenient way for a large number of users to monitor their health and track their daily activities. However, despite their numerous benefits, wearable devices are not without their challenges. One of the most significant issues is the need to recharge their batteries, which can disrupt users’ daily routines and might result in the discontinuation of device use.

Replacing batteries with capacitors and charging them using the available harvested energy from the surrounding environment (e.g., kinetic, thermal, or solar energy) eliminates the burden of recharging or replacing batteries, resulting in convenient, …

Understanding The Role Of Interactivity And Explanation In Adaptive Experiences, Lijie Guo

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Adaptive experiences have been an active area of research in the past few decades, accompanied by advances in technology such as machine learning and artificial intelligence. Whether the currently ongoing research on adaptive experiences has focused on personalization algorithms, explainability, user engagement, or privacy and security, there is growing interest and resources in developing and improving these research focuses. Even though the research on adaptive experiences has been dynamic and rapidly evolving, achieving a high level of user engagement in adaptive experiences remains a challenge. %????? This dissertation aims to uncover ways to engage users in adaptive experiences by incorporating …

Adversarial Deep Learning And Security With A Hardware Perspective, Joseph Clements

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Adversarial deep learning is the field of study which analyzes deep learning in the presence of adversarial entities. This entails understanding the capabilities, objectives, and attack scenarios available to the adversary to develop defensive mechanisms and avenues of robustness available to the benign parties. Understanding this facet of deep learning helps us improve the safety of the deep learning systems against external threats from adversaries. However, of equal importance, this perspective also helps the industry understand and respond to critical failures in the technology. The expectation of future success has driven significant interest in developing this technology broadly. Adversarial deep …

Large Genomes Assembly Using Mapreduce Framework, Yuehua Zhang

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Knowing the genome sequence of an organism is the essential step toward understanding its genomic and genetic characteristics. Currently, whole genome shotgun (WGS) sequencing is the most widely used genome sequencing technique to determine the entire DNA sequence of an organism. Recent advances in next-generation sequencing (NGS) techniques have enabled biologists to generate large DNA sequences in a high-throughput and low-cost way. However, the assembly of NGS reads faces significant challenges due to short reads and an enormously high volume of data. Despite recent progress in genome assembly, current NGS assemblers cannot generate high-quality results or efficiently handle large genomes …

Digitalization Of Construction Project Requirements Using Natural Language Processing (Nlp) Techniques, Fahad Ul Hassan

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Contract documents are a critical legal component of a construction project that specify all wishes and expectations of the owner toward the design, construction, and handover of a project. A single contract package, especially of a design-build (DB) project, comprises hundreds of documents including thousands of requirements. Precise comprehension and management of the requirements are critical to ensure that all important explicit and implicit requirements of the project scope are captured, managed, and completed. Since requirements are mainly written in a natural human language, the current manual methods impose a significant burden on practitioners to process and restructure them into …