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2020

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Articles 1651 - 1680 of 1829

Full-Text Articles in Civil and Environmental Engineering

Comparision Of Fillet-Welded Base Plate Fatigue Design For Highway Support Structures With Laboratory Research Tests, William Shea Jan 2020

Comparision Of Fillet-Welded Base Plate Fatigue Design For Highway Support Structures With Laboratory Research Tests, William Shea

Williams Honors College, Honors Research Projects

There are many types of vertical structures along highways that serve unique purposes. These structures include traffic signs for directing, warning, or regulating traffic, luminaires for distributing and directing light, traffic signals supporting equipment such as traffic lights, and combination structures including any combination of the aforementioned structures. Highway support structures are typically fabricated from steel or aluminum and are designed to the guidelines and specifications of the AASHTO Standard Specifications for Structural Supports for Highway Signs, Luminaires, and Traffic Signals. The structures are connected to a foundation by anchor bolts through a welded base plate. Often a cause …

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Applications Of Ultra-High Performance Concrete, Zachary Plevny Jan 2020

Applications Of Ultra-High Performance Concrete, Zachary Plevny

Williams Honors College, Honors Research Projects

The main objective of this research paper is to determine the current applications of ultra-high performance concrete (UHPC). A second objective is to determine the reason UHPC is used in various applications. More than 17 bridges in the United States have been built with UHPC components. A handful of state departments of transportation have deployed UHPC components within their infrastructure, and many more are actively doing research and considering the use of UHPC. So, this is a relatively new material that is becoming more widely used. The following seven projects, which include UHPC components are discussed in detail: Mars Hill …

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Internet Of Things For Sustainable Mining, Abdul Salam Jan 2020

Internet Of Things For Sustainable Mining, Abdul Salam

Faculty Publications

The sustainable mining Internet of Things deals with the applications of IoT technology to the coupled needs of sustainable recovery of metals and a healthy environment for a thriving planet. In this chapter, the IoT architecture and technology is presented to support development of a digital mining platform emphasizing the exploration of rock–fluid–environment interactions to develop extraction methods with maximum economic benefit, while maintaining and preserving both water quantity and quality, soil, and, ultimately, human health. New perspectives are provided for IoT applications in developing new mineral resources, improved management of tailings, monitoring and mitigating contamination from mining. Moreover, tools …

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The Covid-19 Pandemic And Transportation Engineering, Chris Hendrickson,, Laurence Rilett Jan 2020

The Covid-19 Pandemic And Transportation Engineering, Chris Hendrickson,, Laurence Rilett

Department of Civil and Environmental Engineering: Faculty Publications

The COVID-19 pandemic has been an enormous global disruption with immense economic, environmental, and social impacts throughout the world. Only world wars and the flu pandemic of 1918 are comparable in the wide range of consequences, including fatalities, over a relatively short period of time. Unfortunately, we can expect other major disruptions to occur in the future. In this editorial, we intend to discern some lessons for the transportation engineering profession that can be learned from the current catastrophe that can help us prepare for future disruptions. We will ignore nontransportation aspects of the pandemic such as the development of …

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Experimental Study On The Characteristics Of Formation And Dissociation Of Co2 Hydrates In Porous Media, Amin Hosseini Zadeh, Ijung Kim, Seunghee Kim Jan 2020

Experimental Study On The Characteristics Of Formation And Dissociation Of Co2 Hydrates In Porous Media, Amin Hosseini Zadeh, Ijung Kim, Seunghee Kim

Department of Civil and Environmental Engineering: Faculty Publications

Geologic carbon sequestration (GCS) has pursued as a feasible strategy to store the large amount of CO2 to curb its emission to the atmosphere in an effort to mitigate the greenhouse effects. CO2 hydrate, which can form when the pressure and temperature satisfy its stability condition, can provide a self-trapping mechanism for an offshore CO2 geologic storage. For example, direct sequestration of CO2 in the form of hydrate cystals an be achieved in the storage zone an potentially provide a secondary caprock. These application, however, require a thorough understanding of the formation and dissociation of CO …

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Evaluation And Modeling Of Electrodialysis For High-Recovery Brackish Water Desalination, Shahrouz Jafarzade Ghadimi Jan 2020

Evaluation And Modeling Of Electrodialysis For High-Recovery Brackish Water Desalination, Shahrouz Jafarzade Ghadimi

Open Access Theses & Dissertations

This research investigates the feasibility of desalination of brackish water with electrodialysis (ED), using laboratory testing and mathematical modeling. Several experiments were performed to characterize ion-specific transport and to evaluate tradeoffs between salinity removal and specific energy consumption. A 200 cm2 Ameridia ED stack was used to perform desalination experiments with real brackish groundwater from the Kay Bailey Hutchison desalination plant in El Paso, Texas, and the results showed limiting current density of 160 A/m2 for 5 cm/s. A higher conductivity reduction was observed for flow velocity of 5 cm/s compared to 13 cm/s. Ion transport selectivity (based on relative …

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Impact Of Increased Precipitation On Midwestern Construction, Monica Feltman Jan 2020

Impact Of Increased Precipitation On Midwestern Construction, Monica Feltman

Williams Honors College, Honors Research Projects

This paper presents the current impact of increased precipitation in the Midwest on the construction industry. Mainly, the impact on jobsite safety, increasing insurance rates, and the resulting changes in design codes, or lack thereof. The goal of this independent research is to gather a better understanding of the influence of these changes, because only then can one accurately seek to combat their harmful effects. As a vital element of the global economy, the construction industry must be conscious of their changing relationship with the environment around them. Therefore, understanding the affects of harmful climate change, will increase awareness of …

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A Survey Of Education In Civil Engineering, Tyler Fuller Jan 2020

A Survey Of Education In Civil Engineering, Tyler Fuller

Williams Honors College, Honors Research Projects

This paper provides an overview of the current education requirements in the field of civil engineering. This is achieved through means of an anonymous survey sent to civil engineering academics and data gathered from the published curricula of ten existing civil engineering programs. These ten programs were selected by means of a random number generator from the list of institutions the survey was sent to. Such an overview is important for gauging the effectiveness of civil engineering education for current and future students.

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Steel Bridge Truss Analysis, Alastair Seed Jan 2020

Steel Bridge Truss Analysis, Alastair Seed

Williams Honors College, Honors Research Projects

The purpose of this project is to conduct a study comparing the effectiveness of different cross frame orientations in lowering the deflection of the main stringers of a bridge. Three different orientations of cross frames were researched; vertical, angled with the superstructure webbing, and halfway-angled. All of these were studied when the stringers were placed directly under the superstructure and when the superstructure was placed outside of the stringers. Analysis was performed in a program called SAP 2000 to find the deflections along the stringers under different loading conditions. The results showed that when the superstructure was oriented over the …

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Bs News January/February Jan 2020

Bs News January/February

Building Services Engineering

No abstract provided.

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Assessment Of Different Seismic Retrofit Systems Of Rc Buildings For Earthquake Risk Mitigation, Aya Ragab Mohamed Abou Ei-Hamd Jan 2020

Assessment Of Different Seismic Retrofit Systems Of Rc Buildings For Earthquake Risk Mitigation, Aya Ragab Mohamed Abou Ei-Hamd

Theses

Many existing Reinforced Concrete (RC) structures were designed and constructed at a time when design codes were insufficient according to current standards. This class of structures is at risk of damage when subjected to strong earthquake loading. Therefore, several seismic retrofit techniques have been investigated experimentally to increase the earthquake resistance and damage-control potential of pre-seismic code structures using different methods such as quasi-static and pseudo-dynamic testing. However, a limited number of studies have focused on investigating the overall seismic performance of retrofitted RC structures using shake table testing. The first task of this study assesses analytically and experimentally the …

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Right-Hook Crash Scenario: Effects Of Environmental Factors On Driver's Visual Attention And Crash Risk, Mafruhatul Jannat, Hagai Tapiro, Christopher Monsere, David Hurwitz Jan 2020

Right-Hook Crash Scenario: Effects Of Environmental Factors On Driver's Visual Attention And Crash Risk, Mafruhatul Jannat, Hagai Tapiro, Christopher Monsere, David Hurwitz

Civil and Environmental Engineering Faculty Publications and Presentations

A right-hook (RH) crash is a common type of bicycle–motor vehicle crash that occurs between a right-turning vehicle and through-moving bicycle at an intersection in right-hand driving countries. Despite the frequency and severity of this crash type, no significant driver-performance based evidence of the causes of RH crashes at signalized intersections was found in the literature. This study examined the driver’s visual attention in a right-turning scenario at signalized intersections with bicycle lanes but no exclusive right-turning lanes while interacting with a bicyclist to develop an understanding of RH crash causality. Fifty-one participants in 21 simulated road scenarios performed a …

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Can The Integration Of Bim And Gis Enhance Information Management For Large Scale Linear Infrastructure Projects?, Bim Tudublin, Brendan Kennedy Jan 2020

Can The Integration Of Bim And Gis Enhance Information Management For Large Scale Linear Infrastructure Projects?, Bim Tudublin, Brendan Kennedy

Capstone Reports

The integration of BIM and GIS is the subject of considerable research, particularly as the two coalesce for the purpose of information management. Large scale infrastructure projects require best practice in terms of how information is managed given the volume of information generated throughout the project lifecycle and the numerous parties requiring access to project content. This paper investigates whether the integration of BIM and GIS can enhance information management on large scale linear infrastructure projects. The research comprised a literature review and interviews with a number of BIM/GIS professionals actively working on linear infrastructure projects across the world. Some …

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Evaluation Of An Interview-Based Internship Class In The Construction Management Curriculum: A Case Study Of The University Of Nebraska-Lincoln, Ali Karji, Stuart Bernstein, Mohammadsoroush Tafazzoli, Arash Arash Taghinezhad, Arefeh Mohammadi Jan 2020

Evaluation Of An Interview-Based Internship Class In The Construction Management Curriculum: A Case Study Of The University Of Nebraska-Lincoln, Ali Karji, Stuart Bernstein, Mohammadsoroush Tafazzoli, Arash Arash Taghinezhad, Arefeh Mohammadi

Department of Construction Engineering and Management: Faculty Publications

Internships have been shown to be impactful tools to connect students’ learning in academia with real-world industrial needs. To help the students to get more out of their internship experience, some universities provide a summer internship class in which students do class assignments based on their experiences during their internship. There have been numerous studies on the benefits of internships. However, the benefits of a potential internship class for students in construction management (CM) programs at universities have not yet been investigated. This paper demonstrates the structure of an interview-based internship class and investigates its effectiveness. We have focused on …

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Field Assessment Of Interreplicate Variability From Eight Electromagnetic Soil Moisture Sensors, Tsz Him Lo, Daran Rudnick, Jasreman Singh, Hope Njuki Nakabuye, Abia Katimbo, Derek M. Heeren, Yufeng Ge Jan 2020

Field Assessment Of Interreplicate Variability From Eight Electromagnetic Soil Moisture Sensors, Tsz Him Lo, Daran Rudnick, Jasreman Singh, Hope Njuki Nakabuye, Abia Katimbo, Derek M. Heeren, Yufeng Ge

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Interreplicate variability—the spread in output values among units of the same sensor subjected to essentially the same condition—can be a major source of uncertainty in sensor data. To investigate the interreplicate variability among eight electromagnetic soil moisture sensors through a field study, eight units of TDR315, CS616, CS655, HydraProbe2, EC5, 5TE, and Teros12 were installed at a depth of 0.30 m within 3 m of each other, whereas three units of AquaSpy Vector Probe were installed within 3 m of each other. The magnitude of interreplicate variability in volumetric water content (θv) was generally similar between a static …

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Development And Application Of A Performance And Operational Feasibility Guide To Facilitate Adoption Of Soil Moisture Sensors, Meetpal S. Kukal, Suat Irmak, Kiran Sharma Jan 2020

Development And Application Of A Performance And Operational Feasibility Guide To Facilitate Adoption Of Soil Moisture Sensors, Meetpal S. Kukal, Suat Irmak, Kiran Sharma

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Soil moisture sensors can be effective and promising decision-making tools for diverse applications and audiences, including agricultural managers, irrigation practitioners, and researchers. Nevertheless, there exists immense adoption potential in the United States, with only 1.2 in 10 farms nationally using soil moisture sensors to decide when to irrigate. This number is much lower in the global scale. Increased adoption is likely hindered by lack of scientific support in need assessment, selection, suitability and use of these sensors. Here, through extensive field research, we address the operational feasibility of soil moisture sensors, an aspect which has been overlooked in the past, …

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Effects Of Farrowing Stall Layout And Number Of Heat Lamps On Sow And Piglet Production Performance, Suzanne M. Leonard, Hongwei Xin, Tami M. Brown-Bandl, Brett C. Ramirez, Somak Dutta, Gary A. Rohrer Jan 2020

Effects Of Farrowing Stall Layout And Number Of Heat Lamps On Sow And Piglet Production Performance, Suzanne M. Leonard, Hongwei Xin, Tami M. Brown-Bandl, Brett C. Ramirez, Somak Dutta, Gary A. Rohrer

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Most farrowing facilities in the United States use stalls and heat lamps to improve sow and piglet productivity. This study investigated these factors by comparing production outcomes for three different farrowing stall layouts (traditional, expanded creep area, expanded sow area) and use of one or two heat lamps. Data were collected on 427 sows and their litters over one year. Results showed no statistical differences due to experimental treatment for any of the production metrics recorded, excluding percent stillborn. Parity one sows had fewer piglets born alive (p < 0.001), lower percent mortality (p = 0.001) and over-lay (p = 0.003), and a …

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Influence Of Watershed Characteristics On Streambed Hydraulic Conductivity Across Multiple Stream Orders, Olufemi P. Abimbola, Aaron R. Mittelstet, Troy E. Gilmore, Jesse T. Korus Jan 2020

Influence Of Watershed Characteristics On Streambed Hydraulic Conductivity Across Multiple Stream Orders, Olufemi P. Abimbola, Aaron R. Mittelstet, Troy E. Gilmore, Jesse T. Korus

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Streambeds are critical hydrological interfaces: their physical properties regulate the rate, timing, and location of fluxes between aquifers and streams. Streambed vertical hydraulic conductivity (Kv) is a key parameter in watershed models, so understanding its spatial variability and uncertainty is essential to accurately predicting how stresses and environmental signals propagate through the hydrologic system. Most distributed modeling studies use generalized Kv estimates from column experiments or grain-size distribution, but Kv may include a wide range of orders of magnitude for a given particle size group. Thus, precisely predicting Kv spatially has remained conceptual, experimental, …

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Cover Crop Productivity And Subsequent Soybean Yield In The Western Corn Belt, Katja Koehler-Cole, Roger W. Elmore, Humberto Blanco-Canqui, Charles A. Francis, Charles Shapiro, Christopher A. Proctor, Sabrina J. Ruis, Derek M. Heeren, Suat Irmak, Richard Ferguson Jan 2020

Cover Crop Productivity And Subsequent Soybean Yield In The Western Corn Belt, Katja Koehler-Cole, Roger W. Elmore, Humberto Blanco-Canqui, Charles A. Francis, Charles Shapiro, Christopher A. Proctor, Sabrina J. Ruis, Derek M. Heeren, Suat Irmak, Richard Ferguson

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Cover crops (CC) in corn (Zea mays L.) and soybean [Glycine max (L.) Merr.] rotations may prevent N loss and provide other ecosystem services but CC productivity in the western Corn Belt is limited by the short growing season. Our objective was to assess CC treatment and planting practice effects on CC biomass, spring soil nitrate concentrations, and soybean yield at two rainfed sites in eastern and one irrigated site in south-central Nebraska over 4 years. Cover crop treatments (cereal rye [Secale cereale L.] [RYE] and a mix of rye, legume, and brassica species [MIX]) were planted …

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Calibration Of A Common Shortwave Multispectral Camera System For Quantitative Agricultural Applications, J. Burdette Barker, Wayne Woldt, Brian Wardlow, Christopher Michael Usher Neale, Mitchell S. Maguire, Bryan Leavitt, Derek M. Heeren Jan 2020

Calibration Of A Common Shortwave Multispectral Camera System For Quantitative Agricultural Applications, J. Burdette Barker, Wayne Woldt, Brian Wardlow, Christopher Michael Usher Neale, Mitchell S. Maguire, Bryan Leavitt, Derek M. Heeren

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Unmanned aerial systems (UAS) for collecting multispectral imagery of agricultural fields are becoming more affordable and accessible. However, there is need to validate calibration of sensors on these systems when using them for quantitative analyses such as evapotranspiration, and other modeling for agricultural applications. The results of laboratory testing of a MicaSense (Seattle, WA, USA) RedEdge™ 3 multispectral camera and MicaSense Downwelling Light Sensor (irradiance sensor) system using a calibrated integrating sphere were presented. Responses of the camera and irradiance sensor were linear over many light levels and became non-linear at light levels below expected real-world, field conditions. Simple linear …

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High-Throughput Screening Of Clinically Approved Drugs That Prime Nonviral Gene Delivery To Human Mesenchymal Stem Cells, Tyler Kozisek, Andrew Hamann, Albert Nguyen, Michael Miller, Sarah Plautz, Angela K. Pannier Jan 2020

High-Throughput Screening Of Clinically Approved Drugs That Prime Nonviral Gene Delivery To Human Mesenchymal Stem Cells, Tyler Kozisek, Andrew Hamann, Albert Nguyen, Michael Miller, Sarah Plautz, Angela K. Pannier

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Background: Human mesenchymal stem cells (hMSCs) are intensely researched for applications in cell therapeutics due to their unique properties, however, intrinsic therapeutic properties of hMSCs could be enhanced by genetic modification. Viral transduction is efficient, but suffers from safety issues. Conversely, nonviral gene delivery, while safer compared to viral, suffers from inefficiency and cytotoxicity, especially in hMSCs. To address the shortcomings of nonviral gene delivery to hMSCs, our lab has previously demonstrated that pharmacological ‘priming’ of hMSCs with the glucocorticoid dexamethasone can significantly increase transfection in hMSCs by modulating transfection-induced cytotoxicity. This work seeks to establish a library of transfection …

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Deep Learning Predicts Microbial Interactions From Self-Organized Spatiotemporal Patterns, Joon-Yong Lee, Natalie C. Sadler, Robert G. Egbert, Christopher R. Anderton, Kirsten S. Hofmockel, Janet K. Jansson, Hyun-Seob Song Jan 2020

Deep Learning Predicts Microbial Interactions From Self-Organized Spatiotemporal Patterns, Joon-Yong Lee, Natalie C. Sadler, Robert G. Egbert, Christopher R. Anderton, Kirsten S. Hofmockel, Janet K. Jansson, Hyun-Seob Song

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Microbial communities organize into spatial patterns that are largely governed by interspecies interactions. This phenomenon is an important metric for understanding community functional dynamics, yet the use of spatial patterns for predicting microbial interactions is currently lacking. Here we propose supervised deep learning as a new tool for network inference. An agent-based model was used to simulate the spatiotemporal evolution of two interacting organisms under diverse growth and interaction scenarios, the data of which was subsequently used to train deep neural networks. For small-size domains (100 mm x 100 mm) over which interaction coefficients are assumed to be invariant, we …

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Swine Slurry Characteristics As Affected By Selected Additives And Disinfectants, Jon Duerschner, Shannon L. Bartelt-Hunt, Kent Eskridge, John E. Gilley, Xu Li, Amy M. Schmidt, Daniel D. Snow Jan 2020

Swine Slurry Characteristics As Affected By Selected Additives And Disinfectants, Jon Duerschner, Shannon L. Bartelt-Hunt, Kent Eskridge, John E. Gilley, Xu Li, Amy M. Schmidt, Daniel D. Snow

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Current swine industry practice is to house animals in confinement facilities which capture and store feces and urine as slurry in pits below the production area. Additives and disinfectants may be introduced into the manure pits. This study was conducted to measure the effects of additives and disinfectants on temporal changes in swine slurry characteristics. Slurry from a commercial swine production facility in southeast Nebraska, USA was collected and transferred to 57 L reactors located within a greenhouse. Selected additives and disinfectants were added to the reactors and physical properties, chemical characteristics, and antibiotic concentrations were monitored for 40 days. …

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Influence Of Setback Distance On Antibiotics And Antibiotic Resistance Genes In Runoff And Soil Following The Land Application Of Swine Manure Slurry, Maria C. Hall, Noelle Mware, John E. Gilley, Shannon L. Bartelt-Hunt, Daniel D. Snow, Amy M. Schmidt Schmidt, Kent M. Eskridge, Xu Li Jan 2020

Influence Of Setback Distance On Antibiotics And Antibiotic Resistance Genes In Runoff And Soil Following The Land Application Of Swine Manure Slurry, Maria C. Hall, Noelle Mware, John E. Gilley, Shannon L. Bartelt-Hunt, Daniel D. Snow, Amy M. Schmidt Schmidt, Kent M. Eskridge, Xu Li

Department of Agricultural and Biological Systems Engineering: Faculty Publications

The environmental spread of antibiotics and antibiotic resistance genes (ARGs) from the land application of livestock wastes can be a potential public health threat. The objective of this study was to assess the effects of setback distance, which determines how close manure may be applied in relation to surface water, on the transport of antibiotics and ARGs in runoff and soil following land application of swine manure slurry. Rainfall simulation tests were conducted on field plots covered with wheat residues, each of which contained an upslope manure region where slurry was applied and an adjacent downslope setback region that did …

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Geostatistical Features Of Streambed Vertical Hydraulic Conductivities In Frenchman Creek Watershed In Western Nebraska, Olufemi P. Abimbola, Aaron R. Mittelstet, Troy E. Gilmore Jan 2020

Geostatistical Features Of Streambed Vertical Hydraulic Conductivities In Frenchman Creek Watershed In Western Nebraska, Olufemi P. Abimbola, Aaron R. Mittelstet, Troy E. Gilmore

Department of Agricultural and Biological Systems Engineering: Faculty Publications

This study evaluated the spatial variability of streambed vertical hydraulic conductivity (Kv) in different stream morphologies in the Frenchman Creek Watershed, Western Nebraska, using different variogram models. Streambed Kv values were determined in situ using permeameter tests at 10 sites in Frenchman, Stinking Water and Spring Creeks during the dry season at baseflow conditions. Measurements were taken both in straight and meandering stream channels during a 5 day period at similar flow conditions. Each test site comprised of at least three transects and each transect comprised of at least three Kv measurements. Linear, Gaussian, exponential …

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Evaluation Of Low-Cost Depth Cameras For Agricultural Applications, Isabella C.F.S. Condotta, T. M. Brown-Brandl, Santosh Pitla, John P. Stinn, Késia O. Silva-Miranda Jan 2020

Evaluation Of Low-Cost Depth Cameras For Agricultural Applications, Isabella C.F.S. Condotta, T. M. Brown-Brandl, Santosh Pitla, John P. Stinn, Késia O. Silva-Miranda

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Low-cost depth-cameras have been used in many agricultural applications with reported advantages of low cost, reliability and speed of measurement. However, some problems were also reported and seem to be technology- related, so understanding the limitations of each type of depth camera technology could provide a basis for technology selection and the development of research involving its use. The cameras use one or a combination of two of the three available technologies: structured light, time-of-flight (ToF), and stereoscopy. The objectives were to evaluate these different technologies for depth sensing, including measuring accuracy and repeatability of distance data and measurements at …

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Classification Of Tactile And Motor Velocity-Evoked Hemodynamic Response In Primary Somatosensory And Motor Cortices As Measured By Functional Near-Infrared Spectroscopy, Mohsen Hozan, Jacob Greenwood, Michaela Sullivan, Steven M. Barlow Jan 2020

Classification Of Tactile And Motor Velocity-Evoked Hemodynamic Response In Primary Somatosensory And Motor Cortices As Measured By Functional Near-Infrared Spectroscopy, Mohsen Hozan, Jacob Greenwood, Michaela Sullivan, Steven M. Barlow

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Functional near-infrared spectroscopy (fNIRS) is an emerging technique in studying cerebral hemodynamics; however, consensus on the analysis methods and the clinical applications has yet to be established. In this study, we demonstrate the results of a pilot fNIRS study of cerebral hemodynamic response (HR) evoked by pneumotactile and sensorimotor stimuli on the dominant hand. Our goal is to find the optimal stimulus parameters to maximally evoke HR in the primary somatosensory and motor cortices. We use a pulsatile pneumatic array of 14 tactile cells that were attached to the glabrous surface of the dominant hand, with a patterned stimulus that …

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Glucocorticoid Priming Of Nonviral Gene Delivery To Hmscs Increases Transfection By Reducing Induced Stresses, Andrew Hamann, Tyler Kozisek, Kelly Broad, Angela K. Pannier Jan 2020

Glucocorticoid Priming Of Nonviral Gene Delivery To Hmscs Increases Transfection By Reducing Induced Stresses, Andrew Hamann, Tyler Kozisek, Kelly Broad, Angela K. Pannier

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Human mesenchymal stem cells (hMSCs) are under study for cell and gene therapeutics because of their immunomodulatory and regenerative properties. Safe and efficient gene delivery could increase hMSC clinical potential by enabling expression of transgenes for control over factor production, behavior, and differentiation. Viral delivery is efficient but suffers from safety issues, while nonviral methods are safe but highly inefficient, especially in hMSCs. We previously demonstrated that priming cells with glucocorticoids (Gcs) before delivery of DNA complexes significantly increases hMSC transfection, which correlates with a rescue of transfection-induced metabolic and protein synthesis decline, and apoptosis. In this work, we show …

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Ultrasmall Mixed Eu−Gd Oxide Nanoparticles For Multimodal Fluorescence And Magnetic Resonance Imaging Of Passive Accumulation And Retention In Tbi, Badrul Alam Bony, Hunter A. Miller, Aria W. Tarudji, Connor C. Gee, Anandakumar Sarella, Michael G. Nichols, Forrest Kievit Jan 2020

Ultrasmall Mixed Eu−Gd Oxide Nanoparticles For Multimodal Fluorescence And Magnetic Resonance Imaging Of Passive Accumulation And Retention In Tbi, Badrul Alam Bony, Hunter A. Miller, Aria W. Tarudji, Connor C. Gee, Anandakumar Sarella, Michael G. Nichols, Forrest Kievit

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. TBI can have a long-term impact on the quality of life for survivors of all ages. However, there remains no approved treatment that improves outcomes following TBI, which is partially due to poor delivery of therapies into the brain. Therefore, there is a significant unmet need to develop more effective delivery strategies that increase the accumulation and retention of potentially efficacious treatments in the injured brain. Recent work has revealed that nanoparticles (NPs) may offer a promising approach for site-specific delivery; however, a detailed understanding of the …

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Robotic Detection And Grasp Of Maize And Sorghum: Stem Measurement With Contact, Abbas Atefi, Yufeng Ge, James C. Schnable Jan 2020

Robotic Detection And Grasp Of Maize And Sorghum: Stem Measurement With Contact, Abbas Atefi, Yufeng Ge, James C. Schnable

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Frequent measurements of the plant phenotypes make it possible to monitor plant status during the growing season. Stem diameter is an important proxy for overall plant biomass and health. However, the manual measurement of stem diameter in plants is time consuming, error prone, and laborious. The use of agricultural robots to automatically collect plant phenotypic data for trait measurements can overcome many of the drawbacks of manual phenotyping. The objective of this research was to develop a robotic system that can automatically detect and grasp the stem, and measure its diameter of maize and sorghum plants. The robotic system comprises …

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