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Full-Text Articles in Biochemical and Biomolecular Engineering
Thermal Responsive Release Of A Model Drug, Rhoadmine B, From Alginate Bead System, Heather F. Fairbairn Miss
Thermal Responsive Release Of A Model Drug, Rhoadmine B, From Alginate Bead System, Heather F. Fairbairn Miss
Williams Honors College, Honors Research Projects
Smart drug delivery systems have garnered increased interest in the biomedical community during recent years. Investigation into thermal, pH, and light responsive delivery systems allows for targeted drug release systems to be developed. For this project, thermal responsive release behavior was investigated for the purpose of tuning release systems to achieve 60% release in a specified time by varying the content of thermal responsive polymer. To investigate this, the release profile of a model small hydrophilic drug (rhodamine B) from polymeric alginate beads that have been modified by the addition of thermal responsive poly(N-isopropylacrylamide) (PNIPAAm). It was determined that when …