Open Access. Powered by Scholars. Published by Universities.®

Biochemical and Biomolecular Engineering Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 3 of 3

Full-Text Articles in Biochemical and Biomolecular Engineering

Continuous Liquid-Liquid Extraction Of Lomustine Synthesis, Devna Grover Oct 2021

Continuous Liquid-Liquid Extraction Of Lomustine Synthesis, Devna Grover

The Journal of Purdue Undergraduate Research

No abstract provided.


Elucidating The Effects Of Metabolic State On Nanoparticle Distribution In Mice And In Vitro Uptake, Kevin James Quigley Dec 2016

Elucidating The Effects Of Metabolic State On Nanoparticle Distribution In Mice And In Vitro Uptake, Kevin James Quigley

Doctoral Dissertations

Since almost 70% of the U.S. population over 20 years old is overweight and 30% is obese, with much of the western world following suit, many patients that will potentially be administered circulating nanoparticles designed to localize to tumors and avoid non-target areas will have significant amounts of white adipose tissue (WAT), enlarged livers, and additional metabolic complications such as type 2 diabetes. However, studies on nanoparticle biodistribution and efficacy take place almost without exception in lean rodents with healthy metabolic states. In this work, I determined the biodistribution of model nanoparticles – neutral filomicelles and polystyrene spheres both carrying …


Nanomedicine, Mark Tuominen Jan 2015

Nanomedicine, Mark Tuominen

Nanotechnology Teacher Summer Institutes

An overview of nanomedicine. The end goal of nanomedicine is improved diagnostics, treatment and prevention of disease. Nanotechnology holds key to a number of recent and future breakthroughs in medicine.