Chemical Engineering Commons^™

Effect Of Pre-Adsorbed Species On High-Pressure Adsorption Of Methane In Zeolite 5a Using Grand Canonical Monte Carlo (Gcmc) Simulations, Kanhamardi Lao, Brooks D. Rabideau

Shelby Hall Graduate Research Forum Posters

Natural gas upgrading, which removes impurities from methane (CH4), is essential for industrial applications, including liquefied natural gas (LNG) production and power generation, as well as for residential use. Removing non-hydrocarbon impurities such as carbon dioxide (CO2), nitrogen (N2), and water vapor (H2O), among others, along with separating heavier hydrocarbon gases from raw natural gas, is required to achieve high- purity methane and prevent pipeline corrosion. Zeolite 5A is a microporous aluminosilicate material with a pore size of approximately 5 Å, containing sodium and calcium cations that balance the framework’s negative charge. Its structure offers high thermal stability and a …

Thermophysical Properties Of Aqueous Amine Salts For Closed Air Cabin Revitalization, Mahmud R. Yusuf, Isabela Flores, Ben Hines, Li Hua Zhang, Seth Christa, Brooks D. Rabideau, Kevin West, Breanna Dobyns, James Davis

Shelby Hall Graduate Research Forum Posters

Carbon dioxide (CO2) capture plays a crucial role in closed cabin air revitalization, however current CO2 capture technologies pose several issues. Traditional amine solutions, such as monoethanolamine, are commonly used in CO2 capture on the International Space Station but face drawbacks including high volatility, thermal degradation, and unpleasant odor. To overcome these challenges, amine salt solutions have emerged as promising alternatives. Amine salt solutions have reduced environmental impact, lower corrosion potential, and improved CO2 loading capacity, making them a more efficient and sustainable replacement. Knowing these physical properties are critical for modeling and optimizing a scrubbing process that employs these …

Reinforcing Polymer Flooding System With Dendritic Mesoporous Silica Nanoparticles For Improved Oil Recovery, Di Li, Yanling Wang, Baojun Bai, Ning Xu, Wenjing Shi, Yu Zhang, Wenhui Ding, Peixu Ma, Zan Gao

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Dendritic mesoporous silica nanoparticles (DMSNs), characterized by a high specific surface area and abundant hydroxyl groups, offer a promising approach to enhancing the performance of amphiphilic polymers in challenging enhanced oil recovery (EOR) conditions. In this study, DMSNs were successfully synthesized, and systematically evaluated for their impact on the solution properties of a betaine amphiphilic polymer (PADC). The unique "flower-like" mesoporous structure of DMSNs provided approximately 7-fold higher surface area than conventional SiO2, facilitating enhanced polymer-nanoparticle interactions. The DMSN/PADC composite system exhibited significantly improved viscosity, salt resistance, thermal tolerance, and shear resistance compared to PADC and SiO2/PADC systems. Quantum chemical …

Optimization And Dft Study For Boosted Electooxidation Of Formic Acid At Niox Modified Pt Using Urea Derivatives As Blending Fuels, Aya Saada

Biochemical Engineering

This paper addresses the enhancement of formic acid electrooxidation (FAO) at Pt and Pt-NiOx nanoparticles based-catalysts assisted with urea derivatives as blending fuels. Blending formic acid with various ratios of urea derivatives showed noticeable enhancements of FAO as demonstrated by a favorable negative shift of its onset potential (Eonset) and increase of its peak current density concurrently with suppression of the amount of CO poisoning reaction intermediate. Among all the used derivatives, phenyl urea (PU) showed superior enhancing effect towards the direct FAO with a minimal CO formation together with a favorable negative shift of Eonset by 150 mV. The …

Effectiveness Of Natural Coagulants In Purification Of Industrial Wastewater: A Case Of Cactus Pads And Watermelon Seeds, Neema O. Msuya

Tanzania Journal of Engineering and Technology (TJET)

This study assessed the potential of cactus pads and watermelon seeds as natural coagulants in industrial wastewater treatment. The global characterization of the two coagulants was done by using the Fourier Transform Infrared (FTIR) to determine the specific functional groups and by zeta potential measurements. A full factorial design was used to design the experiment and analyze the effect of three factors: coagulant dosage, settling time and particle size with three levels each and one replicate on the turbidity removal. ANOVA analyses were used to determine the significance of the factors. Results show that the amino and hydroxyl groups in …

Integrating Medical Plastic Waste Pyrolysis And Circular Economy For Environmental Sustainability, Attia Attia, Mohamed Bassyouni Prof., Reem Nasser Eng., Moataz El-Bagoury Eng., Islam Shaker Eng., Yasser Elhenawy Prof., Dina Aboelela Dr.

Biochemical Engineering

A critical assessment of pyrolysis technologies and reactor designs was discussed, highlighting various reactor configurations. This study explored the influence of catalysts, temperature, heating rate, and residence time on the pyrolysis process, and addressed their effects on product distribution and composition. Safety considerations and strategies for mitigating the potential environmental impacts of pyrolysis were presented. Comparative analyses of the environmental impacts of traditional waste disposal methods versus pyrolysis-based approaches provided insights into the potential reduction of greenhouse gas emissions and other pollutants. The circular economy approach was explored in the context of medical plastic waste pyrolysis. The potential for closing …

Using Preformed Particle Gels To Control Transport In Geothermal Reservoirs: Mathematical Modeling, Philip Winterfeld, Baojun Bai, Yu Shu Wu

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

We are developing swellable Preformed Particle Gels (PPG), which can control preferential fluid and heat flow through fracture networks to increase the performance of EGS reservoirs. Part of this development is a mathematical model and numerical simulator to simulate PPG treatments by considering coupled thermal-hydraulic-mechanical effects, and gel swelling kinetics and plugging efficiency, from which an optimized gel treatment design and operation can be achieved. The starting point for our mathematical model is the TOUGH2-CSM formulation and code. The TOUGH2-CSM fluid and heat flow formulation is based on the TOUGH2 one for multiphase, multicomponent, and multi-porosity systems, with the latter …

The Antibiofilm Efficacy Of Copper And Zinc-Enhanced Borate Bioactive Glasses On Polymicrobial Biofilms, Sarah Fakher, David J. Westenberg

Biological Sciences Faculty Research & Creative Works

Healthcare-acquired infections (HAIs) are a significant global challenge driven by biofilm-forming pathogens. Polymicrobial biofilms, involving interactions between multiple microbial species, exacerbate treatment difficulties due to their enhanced resistance to antimicrobial therapies. Borate bioactive glasses (BBGs) are an emerging class of biomaterials that have attracted significant interest in infection control. The incorporation of copper and zinc into the BBG matrix can effectively disrupt biofilm formation and bacterial colonization. This study investigates the antibiofilm efficacy of copper and zinc-doped BBGs against polymicrobial biofilms formed by S. epidermidis, E. coli, and P. aeruginosa. Using static and dynamic biofilm models, BBGs were applied through …

Investigation Of Dynamic Adsorption And Desorption Of Polymer Nanogel In Porous Media Through Microfluidics, Junchen Liu, Fuqiao Bai, Abdulaziz A. Almakimi, Mingzhen Wei, Xiaoming He, Ibnelwaleed A. Hussein, Baojun Bai

Mathematics and Statistics Faculty Research & Creative Works

Understanding the transport and retention of elastic nanogel and microgel particles in porous media has been a significant research subject for decades, essential to the application of enhanced oil recovery (EOR). However, a lack of dynamic adsorption and desorption studies, in which the kinetics in porous media are seldom investigated, hinders the design and application of polymer nanogel in underground porous media. In this work, we visualized and quantified the transport and dynamic adsorption of polymer nanogel in 3D glass micromodels that were manufactured by packing glass beads in capillaries. Calibrating the linearity of fluorescence intensity to concentration, we calculated …

Graphite Particles Modified By Zno Atomic Layer Deposition For Li-Ion Battery Anodes, Ahmad Helaley, Han Yu, Xinhua Liang

Chemical and Biochemical Engineering Faculty Research & Creative Works

Graphite, with a modest specific capacity of 372 mA h g−1, is a stable material for lithium-ion battery anodes. However, its capacity is inadequate to meet the growing power demands because the formation of an irregular solid electrolyte interphase (SEI) can result in unstable performance. In this research, we used a few cycles of atomic layer deposition (ALD) to deposit ZnO on graphite particles as an anode with improved electrochemical stability. Transmission electron microscopy revealed that ZnO was in the form of nanoparticles due to the inert surface properties of graphite and only a few cycles of ALD. Electrochemical characterization …

Modeling Ion-Specific Effects In Polyelectrolyte Brushes: A Modified Poisson-Nernst-Planck Model, William J. Ceely, Marina Chugunova, Ali Nadim, James D. Sterling

Business and Information Technology Faculty Research & Creative Works

Polyelectrolyte brushes consist of a set of charged linear macromolecules, each tethered at one end to a surface. An example is the glycocalyx which refers to hair-like negatively charged sugar molecules that coat the outside membrane of all cells. We consider the transport and equilibrium distribution of ions and the resulting electrical potential when such a brush is immersed in a salt buffer containing monovalent cations (sodium and/or potassium). The Gouy-Chapman model for ion screening at a charged surface captures the effects of the Coulombic force that drives ion electrophoresis and diffusion but neglects non-Coulombic forces and ion pairing. By …

Predictive Modeling For Optimal Gel Treatment Design In Brownfields Using Ensemble Machine Learning And Data Upsampling Via Generative Ai, Munqith Aldhaheri, Baojun Bai, Mingzhen Wei

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Efficiently designed gel treatments play a vital role in extending the lifespan of brownfields through rejuvenating oil production. Recently, a three-mode mathematical methodology named the VCR approach has been proposed for designing effective treatments. To optimize this approach, it is crucial to determine the appropriate design mode systematically rather than relying solely on the intuitive judgments of field operators. This study introduces an advanced methodology for predicting the optimal design type of gel treatments using 12 reservoir and production variables. The methodology integrates ensemble machine-learning (EML) models with historical data from 65 field projects across 11 countries (1985-2020). The Random …

Quantifying The Effectiveness Of Rhamnolipid As A Biocide: Assessing Comparability Of A Modified Solution, Rosemary Sterling

Williams Honors College, Honors Research Projects

The CO2 induced corrosion of carbon steel in oil and gas pipelines, exacerbated by sulfate-reducing bacteria (SRB), poses a serious threat to infrastructure. This study evaluates the effectiveness of rhamnolipid (RhL), a biosurfactant, as a corrosion inhibitor and potential SRB biocide in simulated pipeline environments. Using a Postgate-C Modified Produced Water Simulant, which demonstrated electrochemical behavior comparable to industry-standard solutions while sustaining SRB, corrosion trials were conducted with and without RhL. Mass loss and electrochemical data revealed that RhL significantly reduced corrosion rates—by 85% on average and up to 99% instantaneously in a 4-day trial. Visual and analytical results from …

Influence Of Fused Deposition Modeling Process Parameters On The Constitutive Model Of Hyperelastic Thermoplastic Polyurethane, Lucas Gallup, Mohamed Trabia, Brendan O'Toole, Youssef Fahmy

Mechanical Engineering Faculty Research

Thermoplastic polyurethanes (TPUs) are suited for fused deposition modeling (FDM) of parts that require high levels of flexibility and strength. Predicting the deformation of TPU parts produced using FDM may be difficult, especially under large deformations, as their constitutive models depend on the printing process parameters. The lack of understanding led to the absence of constitutive models for TPU parts produced using FDM. This work aims to identify accurate hyperelastic constitutive models. Six groups of uniaxial tensile specimens were produced using FDM. These groups were made with variations in two process parameters, which were infill geometry and extrusion nozzle temperature. …

Determination Of The Kinetic Parameters Of Cholesterol Oxidation Using Cholesterol Oxidase From Streptomyces Sp., Meka Saima Perdani, Heri Hermansyah, Muhamad Sahlan, Dwini Normayulisa Putri, Teguh Pambudi, Anggi Khairina Hanum Hasibuan

Makara Journal of Technology

Cholesterol oxidase (CO) was successfully produced from Streptomyces sp. via the submerged fermentation method, and 69 U/mL enzyme activity was obtained. This study aimed to determine cholesterol oxidation kinetics and the production of CO as a catalyst. The enzyme was diluted to 0.15, 0.075, and 0.00375 U/mL for the oxidation reaction. The substrate was also prepared in three concentrations: 3.23, 6.46, and 12.93 mM. The optimization of conditions for enzymatic cholesterol oxidation was investigated through measurement of the effect of initial cholesterol and enzyme concentrations. Cholesterol concentration was rapidly measured via high-performance liquid chromatography (HPLC). The kinetics of CO were …

Zeolite 13x Particles With Porous Tio2 Coating And Ag2o Nanoparticles As Multi-Functional Filler Materials For Face Masks, Wei Su, Kaiying Wang, Han Yu, Fateme Fayyazbakhsh, Jeremy Watts, Yue-Wern Huang, Jee-Ching Wang, Xinhua Liang

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Adsorbent components in face masks are crucial for protecting individuals exposed to dangerous situations. In this study, one porous TiO₂ layer was deposited on zeolite 13X particles by coating hybrid organic/inorganic titanium alkoxide film via molecular layer deposition (MLD), followed by heat treatment to remove organic components in the MLD film. Various concentrations of Ag₂O nanoparticles were impregnated on the TiO₂-coated 13X particles, offering a wide range of antibacterial, antifungal, and antiviral characteristics. The obtained composite particles were characterized using X-ray photoelectron spectroscopy and thermal gravimetric analysis to study the composition and mass loading of …

Magnetic Resonance Imaging Trackable Pathology-Triggered Polymersomes Toward Enzyme Replacement Theranostics For Gm1 Gangliosidosis, Dorian Foster

All Dissertations

This dissertation investigates the development and optimization of pathology-responsive polymersomes for simultaneous enhanced magnetic resonance imaging (MRI) and enzyme replacement therapy (ERT) in the treatment of GM1 gangliosidosis (GM1). While therapeutic strategies exist for similar, non-neuropathic lysosomal storage disorders, implementation towards GM1 faces significant challenges due to the blood-brain barrier.

Herein, we developed and characterized a range of low molecular weight hyaluronic acid-b-polylactic acid (HA-PLA) polymersomes (PSs) capable of encapsulating therapeutic enzymes in their hydrophilic core. These polymersomes exhibit pathophysiology-triggered responsiveness, degrading in the presence of acidic conditions, which is characteristic of lysosomes, and enzymes such as hexosaminidase A, which …

Experimental Evaluation Of A Recrosslinkable Co2-Resistant Micro-Sized Preformed Particle Gel For Co2 Sweep Efficiency Improvement In Reservoirs With Super-K Channels, Adel Alotibi, Tao Song, Ali Al Brahim, Baojun Bai, Thomas P. Schuman

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

A recross linkable CO₂-resistant branched preformed particle gel (CO₂-BRPPG) was developed for controlling CO₂ injection conformance, particularly in reservoirs with super-permeable channels. Previous work focused on a millimeter-sized CO₂-BRPPG in open fractures, but its performance in high-permeability channels with pore throat networks remained unexplored. This study used a sand pack model to evaluate a micro-sized CO₂-BRPPG under varying conditions of salinity, gel concentration, and pH. at ambient conditions, the equilibrium swelling ratio (ESR) of the gel reached 76 times its original size. This ratio decreased with increasing salinity but remained stable …

The Design And Implementation Of A Modular Tissue Engineering Test Bed To Pursue An Alternate Pathway Of Cell Culture Based Research, Ryley Patrick Griffin

Theses and Dissertations

The development of a Modular Automated Tissue Engineering Test Bed (MATETB) is the next step in the development of cheap and easily available in vitro cell regulatory systems for both academic and industrial purposes. This project outlined the framework and requirements for a device that could automatically regulate and collect data on a cell culture through the manipulation of its liquid environment. From this framework, a prototype was built. The device would fulfill cell culture needs while collecting data automatically and allowing for live viewing and imaging of cells. The device was comprised of a mechanical skeleton (MS), an environmental …

Development And Characterization Of Organic Electrocatalysts For Use In Zinc-Air Batteries, Christopher John Merkel

Department of Chemical and Biomolecular Engineering: Dissertations, Theses, and Student Research

The global deployment of solar photovoltaic and wind power is projected by the International Energy Agency as the primary pathway to reduce dependence on fossil fuels. However, these technologies face a critical bottleneck: their inherently intermittent power generation. For “intermittent renewables” to become the dominant source of electrical energy, efficient energy storage systems are essential. Current storage solutions are not viable on a global scale due to material scarcity, safety concerns, and high capital costs. Among emerging technologies, zinc-air batteries (ZABs) have garnered significant interest. ZABs offer a theoretical energy density five times greater than traditional lithium-ion batteries, utilize safe …

Boosting The Power Performance Of Microbial Fuel Cells By Using Dual Nanomaterial-Modified Carbon Felt Electrodes, Krishna Thapa, Wenyan Liu, Yuwei Zhang, David J. Westenberg, Yishu Zhou, Risheng Wang

Chemistry Faculty Research & Creative Works

Innovative design enhancements to microbial fuel cells (MFCs) are pivotal for improving their viability as renewable energy sources. This study introduces a dual approach to electrode modification, integrating polyaniline (PANI) and gold nanoparticles (AuNPs) on carbon felt (CF) anodes coupled with a unique cathode composed of DNA origami and chitosan. The synergistic effect of PANI and AuNPs significantly increases the hydrophilicity and conductivity of the anode, leading to a considerable surge in power density. Concurrently, the biocompatible DNA origami and chitosan-functionalized cathode facilitates efficient electron transfer without relying on conventional catalysts. Together, these modifications yield a 52.42% increase in the …

Process Development And Techno-Economic Analysis For Combined And Separated Co2 Capture-Electrochemical Utilization, Abdullah Al Moinee, Ali A. Rownaghi, Fateme Rezaei

Chemical and Biochemical Engineering Faculty Research & Creative Works

Combining CO₂ capture and utilization into a single unit operation offers a feasible solution for converting a sustainable feedstock into marketable commodity chemicals, while reducing energy requirements from separated processes. In this research, we developed a process model and performed a techno-economic analysis (TEA) for point-source CO₂ capture and electrochemical-based utilization in light olefins production under both separated and integrated scenarios. CO₂ containing flue gas from a 500 MW power plant was utilized as a feed while CO₂ utilization involved electrochemical reduction reactions to produce light olefins directly from CO₂. A meticulous analysis was …

Biocargos: Capture And Release Gels For Room Temperature Cell Storage., Justin Jacobson

Electronic Theses and Dissertations

Currently, cryovials on dry ice or liquid nitrogen vapor transportation vessels are primary ways utilized to transport mammalian cells from one location to another. Due to the safety concerns of dry ice and liquid nitrogen, associated costly shipping charges, and limitations of proper packaging and labeling of materials, these conventional shipping techniques are unacceptable. It is urgent to develop a safe and environmentally friendly protocol to preserve and ship the biological samples from one place to another. In this research, a method was developed for an ecofriendly and safe protocol to preserve cancer cells. The cell viability of cell line …

Atomic Layer Deposition Of Ru Nanoclusters On Ba-Laceox: A Highly Efficient Catalyst For Ammonia Synthesis Under Mild Conditions, Kaiying Wang, Baitang Jin, Xiaoqing He, Xinhua Liang

Chemical and Biochemical Engineering Faculty Research & Creative Works

Ammonia synthesis has significant implications for global energy and environmental issues, driving the need for highly active catalysts that operate under mild conditions. This study reports the successful deposition of uniform ∼1.0 nm metallic ruthenium (Ru) nanoclusters onto Ba-LaCeO_x particles via atomic layer deposition (ALD). The catalytic performance of the ALD-prepared Ru nanoclusters was assessed for ammonia synthesis and compared with two catalysts produced by conventional incipient wetness impregnation. For the ALD-prepared Ru nanoclusters, a pre-reaction H_2-reduction step induced partial encapsulation of suboxide species on Ru sites due to strong metal-support interactions, limiting Ru nanocluster sintering and …

Carboxymethyl Cellulose-Based Preformed Particle Gels For Water Management In Oil And Gas Reservoirs, Ahmed Ben Ali, Ahmed Hamza, Abdulaziz A. Almakimi, Mohammed Saad, Ibnelwaleed A. Hussein, Baojun Bai

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Carboxymethyl cellulose (CMC) based materials have been proposed as preformed particle gels (PPGs) for reducing excessive water production in oil and gas reservoirs. Multi-sized dry particles ranging between 100 and 1180 μm have been synthesized using microwave-assisted grafting copolymerization of CMC and acrylamide (AM)/n,n''-methylene-bisacrylamide (MBA). FTIR and SEM confirmed CMC crosslinked polyacrylamide's chemical structure and morphology (CMC/CPAM). Thermo-gravimetric analysis has demonstrated the thermal stability of dry PPGs up to 309 °C. CMC/CPAM showed slightly high absorbency in brine 2 (TDS = 67.3 g/L) compared to brine 1 (TDS = 33.65 g/L), 1% NaCl, and deionized water, with swelling ratios (SR) …

The Effectiveness Of Certain Biological Additives Considered By-Products Of The Food Industry In Baker’S Yeast Activation, Nataliya E. Kulikova, Antonina G. Chernobrovina, Natalia N. Roeva

CHEMISTRY AND CHEMICAL ENGINEERING

One of the ways to increase the efficiency of the activation process of baking yeast is the use of waste and by-products of the food industry as nutrient media. The goal of the study was to develop ways to activate yeast in a nutrient medium with dietary supplements: potato cell sap, whey and quince pomace powder. We demonstrated the effectiveness of the use of biological additives (potato cell juice, quince pomace powder, whey), which are waste or by-products of the food industry to activate yeast. We have established that incubation in a nutrient medium with dietary supplements has a beneficial …

Glycerol-Free Biodiesel Via Catalytic Interesterification: A Pathway To A Netzero Biodiesel Industry, Nessren Farrag, Omar Youssef Youssef, Esraa Khaled, Omar Aboelazayem

Chemical Engineering

Conventional biodiesel manufacturing uses alcohol as an acyl acceptor, resulting in glycerol as a side product. The increased demand for biodiesel has led to the production of a substantial surplus of glycerol, exceeding the market need. Consequently, glycerol is now being regarded as a byproduct, and in some cases, even as waste. The present study aims to suggest an economically viable and ecologically friendly approach for maintaining the viability of the biodiesel sector. This involves generating an alternative byproduct of higher value, rather than glycerol. Triacetin is produced through the interesterification of triglycerides with methyl acetate, and is a beneficial …

Enhancing Ammonium And Bicarbonate Tolerance In Chlorella Sorokiniana Through Ems-Induced Mutagenesis, Wentao Yang

McKelvey School of Engineering Graduate Student Theses & Dissertations

This study explores the enhancement of ammonium and bicarbonate tolerance in Chlorella sorokiniana via EMS-induced mutagenesis, aimed at improving the microalgae's resilience and growth under high-stress conditions of elevated NH4+ and HCO3 concentrations. By mutating C. sorokiniana using EMS, we developed mutant strains capable of thriving in conditions that are inhibitory to the wild type strain. The successful adaptation of these strains demonstrates a significant increase in biomass production and tolerance to environmental stressors, highlighting the potential of EMS mutagenesis in industrial algal applications for sustainable biofuel production and environmental remediation.

A New Air-Assisted Flare Tip Design For Managing Gas Flare Emissions (Cfd Analysis), Ahmed A. Maaroof, Joseph D. Smith, Mohammed H.S. Zangana

Chemical and Biochemical Engineering Faculty Research & Creative Works

Recently, flares have been considered as a major source of air pollution from the petroleum refining industry. The United Nations has instigated an international effort related to the management of flare emissions to reduce the global warming impact related to flaring. Eliminating or removing the need for gas flares is difficult because these devices are generally used as safety devices to allow the combustion of flammable gases in a controlled fashion which supports safe operation. However, reducing flaring is generally possible using well-designed, efficiently operated flare equipment. In general, flare performance can be enhanced following the API-521 methodology and using …

Antibiotic-Loaded Dendrimer Hydrogels In Periodontal Bone Regeneration: An In Vitro Release Feasibility Study, Nicholas Yesbeck, Da Huang, Caroline Carrico, Parthasarathy Madurantakam, Hu Yang

Chemical and Biochemical Engineering Faculty Research & Creative Works

The prescription of a course of oral antibiotics following bone grafting procedures is a common practice in clinical periodontics to reduce surgical site infections. The goal of this study is to characterize the release profile of antibiotics via local delivery using dendrimer hydrogels (DH) and to analyze the effect of two different particulate bone allografts on the release of the antibiotics in vitro. DH were synthesized from Poly amidoamine (PAMAM) dendrimer G5 and polyethylene glycol diacrylate, and cefazolin was chosen as the antibiotic. The antibiotic-loaded samples were bathed in PBS and incubated at 37 °C; aliquots were taken (1 h, …