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Full-Text Articles in Vision Science

Investigation Into Intraocular Pressure Distribution Via Computer Aided Engineering (Cae), Madison Maureen Hinman Jul 2025

Investigation Into Intraocular Pressure Distribution Via Computer Aided Engineering (Cae), Madison Maureen Hinman

Masters Theses

The leading cause for irreversible blindness and vision loss is glaucoma - an eye condition associated with elevated intraocular pressure (IOP). Increased IOP is also seen during other pathological conditions like spaceflight-associated neuro-ocular syndrome (SANS), and non-pathological conditions as when playing a wind instrument. The study aimed to describe the influence of different vitreous cavity size as well as vitreous fluid viscosity on the IOP as measured at the back of the eye on the retina. Improved understanding of eye pressure transmission can aid in a better understanding of eye diseases. The experiment conducted included cavities of varying size and …


A Microfluidic Tissue Array (Μfta) For Personalized Medicine Using Tumor Biopsies, A.H. R. Ahmed Jan 2019

A Microfluidic Tissue Array (Μfta) For Personalized Medicine Using Tumor Biopsies, A.H. R. Ahmed

Dissertations and Theses

Cancer is recognized as a complex disease with both genetic and epigenetic drivers that can vary from one individual to another. While very early research into cancer treated it as a clonal malfunction that could originate from as small as a single deregulated cell, the disease itself manifests itself with several more complexities beyond tumorigenic cells only. The tumor microenvironment itself – from the extracellular matrix to stromal cells - cooperate with tumor cells in a symbiotic manner towards metastatic progression. Clinical studies have provided more information regarding the degree of individualization possible, such that patients with similar genetic makeup …