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Bioimaging and Biomedical Optics Commons™
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Articles 1 - 6 of 6
Full-Text Articles in Bioimaging and Biomedical Optics
Evaluation Of Segmentation For Bone Structures In 3d Rendering Of Ultrasound Residual Limb Images, Min C. Baker
Evaluation Of Segmentation For Bone Structures In 3d Rendering Of Ultrasound Residual Limb Images, Min C. Baker
Theses and Dissertations
Prosthetists today widely practice manual socket fitting, which produces subjective, inconsistent results. To address this problem, the Computerized Anthropometry Research and Design (CARD) Laboratory is developing a computer-aided socket design system that acquires ultrasound datasets of an amputee's residual limb, creates a 3D model, and helps identify load- bearing and pressure-relief areas. This research project focuses on providing 3D visualization of a residual limb to support the CARD Laboratory's efforts. Creating the 3D model of the skin and two bone contours requires two major steps: segmentation to identify the objects of interest and a surface tracking algorithm to generate the …
Pulse Coupled Neural Networks For The Segmentation Of Magnetic Resonance Brain Images, Shane L. Abrahamson
Pulse Coupled Neural Networks For The Segmentation Of Magnetic Resonance Brain Images, Shane L. Abrahamson
Theses and Dissertations
This research develops an automated method for segmenting Magnetic Resonance (MR) brain images based on Pulse Coupled Neural Networks (PCNN). MR brain image segmentation has proven difficult, primarily due to scanning artifacts such as interscan and intrascan intensity inhomogeneities. The method developed and presented here uses a PCNN to both filter and segment MR brain images. The technique begins by preprocessing images with a PCNN filter to reduce scanning artifacts. Images are then contrast enhanced via histogram equalization. Finally, a PCNN is used to segment the images to arrive at the final result. Modifications to the original PCNN model are …
Using Kriging To Interpolate Spatially Distributed Volumetric Medical Data, Stephen M. Matechik
Using Kriging To Interpolate Spatially Distributed Volumetric Medical Data, Stephen M. Matechik
Theses and Dissertations
Routine cases in diagnostic radiology require the interpolation of volumetric medical imaging data sets. Inaccurate renditions of interpolated volumes can lead to the misdiagnosis of a patient's condition. It is therefore essential that interpolated modality space estimates accurately portray patient space. Kriging is investigated in this research to interpolate medical imaging volumes. Kriging requires data to be spatially distributed. Therefore, magnetic resonance imaging (MRI) data is shown to exhibit spatially regionalized characteristics such that it can be modeled using regionalized variables and subsequently be interpolated using kriging. A comprehensive, automated, three-dimensional structural analysis of the MRI data is accomplished to …
Clustered Microcalcification Detection Using Optimized Difference Of Gaussians, Edward M. Ochoa
Clustered Microcalcification Detection Using Optimized Difference Of Gaussians, Edward M. Ochoa
Theses and Dissertations
The objective of this thesis is to design an automated microcalcification detection system to be used as an aid in radiologic mammogram interpretation. This research proposes the following methodology for clustered microcalcification detection. First, preprocess the digitized film mammogram to reduce digitization noise. Second, spatially filter the image with a difference of Gaussians (DoG) kernel. To detect potential microcalcifications, segment the filtered image using global and local thresholding. Next, cluster and index these detections into regions of interest (ROIs). Identify ROIs on the digitized image (or hardcopy printout) for final radiologic diagnosis.
Validation Of Energy Dispersive X-Ray Spectrometry As A Method To Standardize Backscattered Electron Images Of Bone, E. G. Vajda, R. D. Bloebaum, J. G. Skedros
Validation Of Energy Dispersive X-Ray Spectrometry As A Method To Standardize Backscattered Electron Images Of Bone, E. G. Vajda, R. D. Bloebaum, J. G. Skedros
Cells and Materials
The use of backscattered electron (BSE) imaging as a tool for the qualitative measurement of mineral content in bone has been well documented. The challenge still remains to develop BSE imaging as a tool for quantitative mineral content analysis in bone. The limiting factor has been the ability to standardize the BSE signal within and between laboratories. Energy dispersive x-ray spectrometry (EDX) has been proposed as a method to standardize the BSE operating environment. The goal of this study is to investigate the relationship between EDX-determined wt.% Ca measurements and BSE graylevels. A comparison with traditional ash content measurements will …
The Influence Of Acoustic Impedance Mismatch On Post-Stenotic Pulsed-Doppler Ultrasound Measurements In A Coronary Artery Model, S. A. Jones, H. Leclerc, George P. Chatzimavroudis, Y. H. Kim, N. A. Scott, Ajit P. Yoganathan
The Influence Of Acoustic Impedance Mismatch On Post-Stenotic Pulsed-Doppler Ultrasound Measurements In A Coronary Artery Model, S. A. Jones, H. Leclerc, George P. Chatzimavroudis, Y. H. Kim, N. A. Scott, Ajit P. Yoganathan
Chemical & Biomedical Engineering Faculty Publications
Acoustic impedance mismatch at the fluid-wall interface was shown to affect the spectra from an intravascular Doppler device in an in vitro model with a diameter typical of human coronary arteries. Measurements were obtained first under Poiseuille flow conditions with impedance mismatches of 0%, 7% and 12%, and then under stenosed conditions for the 0% and 7% mismatch cases. For the zero mismatch case, the Doppler spectra could be readily interpreted in terms of fluid mechanical phenomena. When mismatch was present, the spectra from Poiseuille flow exhibited multiple peaks which could not be directly related to the velocity profile. Also, …