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Biomedical Engineering and Bioengineering Commons™

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2007

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Articles 61 - 90 of 174

Full-Text Articles in Biomedical Engineering and Bioengineering

Nutrient Concentrations Of Runoff During The Year Following Manure Application, John E. Gilley, Bahman Eghball, D. B. Marx Aug 2007

Nutrient Concentrations Of Runoff During The Year Following Manure Application, John E. Gilley, Bahman Eghball, D. B. Marx

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Little information is currently available concerning temporal changes in nutrient transport following the addition of manure to cropland areas. This study was conducted to measure nutrient transport in runoff as affected by tillage and time following the application of beef cattle or swine manure to a site on which corn (Zea mays L.) was grown. Rainfall simulation tests were initiated 4, 32, 62, 123, and 354 days following land application. Three 30 min simulated rainfall events, separated by 24 h intervals, were conducted at an intensity of approximately 70 mm h-1. Dissolved phosphorus (DP), particulate phosphorus (PP), total phosphorus …


Pulmonary Microvascular Injury Resulting From A Single Exposure To Low-Dose Thoracic Radiation, Q. Wu, G. Schmirler, John E. Moulder, Elizabeth R. Jacobs, Meetha Medhora, Robert C. Molthen Aug 2007

Pulmonary Microvascular Injury Resulting From A Single Exposure To Low-Dose Thoracic Radiation, Q. Wu, G. Schmirler, John E. Moulder, Elizabeth R. Jacobs, Meetha Medhora, Robert C. Molthen

Biomedical Engineering Faculty Research and Publications

No abstract provided.


Influence Of Acid Washing On The Surface Morphology Of Ionomer Glasses And Handling Properties Of Glass Ionomer Cements, C. M. Crowley, J. Doyle, Mark R. Towler, N. Rushe, S. Hampshire Aug 2007

Influence Of Acid Washing On The Surface Morphology Of Ionomer Glasses And Handling Properties Of Glass Ionomer Cements, C. M. Crowley, J. Doyle, Mark R. Towler, N. Rushe, S. Hampshire

Chemical and Biochemical Engineering Faculty Research & Creative Works

Acid washing is known to influence the handling properties of ionomer glasses used in glass ionomer cements due to the production of an ion depleted zone on the surface of the glass particles. The influence of acid washing on the particle size distribution and surface area of four glasses was examined by scanning electron microscopy (SEM), particle size analysis (PSA) and accelerated surface area porosimetry (ASAP) and the working and setting times of cements, produced from the glasses, correlated to changes in surface morphology. A linear relationship was found between the specific surface area of acid-washed SiO2-Al2 …


D-4f Does Not Mitigate Key Parameters In Rat Model Of Severe Pulmonary Hypertension, Robert C. Molthen, Shelley Baumgardt, K. A. Pritchard Jr Aug 2007

D-4f Does Not Mitigate Key Parameters In Rat Model Of Severe Pulmonary Hypertension, Robert C. Molthen, Shelley Baumgardt, K. A. Pritchard Jr

Biomedical Engineering Faculty Research and Publications

No abstract provided.


Design And Validation Of A Mr-Compatible Pneumatic Manipulandum, Aaron J. Suminski, Janice L. Zimbelman, Robert A. Scheidt Jul 2007

Design And Validation Of A Mr-Compatible Pneumatic Manipulandum, Aaron J. Suminski, Janice L. Zimbelman, Robert A. Scheidt

Biomedical Engineering Faculty Research and Publications

The combination of functional MR imaging and novel robotic tools may provide unique opportunities to probe the neural systems underlying motor control and learning. Here, we describe the design and validation of a MR-compatible, 1 degree-of-freedom pneumatic manipulandum along with experiments demonstrating its safety and efficacy. We first validated the robot's ability to apply computer-controlled loads about the wrist, demonstrating that it possesses sufficient bandwidth to simulate torsional spring-like loads during point-to-point flexion movements. Next, we verified the MR-compatibility of the device by imaging a head phantom during robot operation. We observed no systematic differences in two measures of MRI …


Improving Pediatric Cardiology Consultation Methods By Introducing Digital Interactive 3-D Heart Models: A Proof Of Concept Study, Adam Verigan Jul 2007

Improving Pediatric Cardiology Consultation Methods By Introducing Digital Interactive 3-D Heart Models: A Proof Of Concept Study, Adam Verigan

USF Tampa Graduate Theses and Dissertations

The purpose of a pediatric cardiology consultation is to inform, or educate, the patient and family of all aspects surrounding a certain congenital heart defect. Consultation education methods and materials may include verbal descriptions, two-dimensional (2-D) heart diagrams, and take-home pamphlets. Because the human heart is a complex three-dimensional (3-D) object, the problem lies within the clarity to which these methods are performed by the doctors and understood by the patients and families. Therefore, during a consultation the cardiologist must a) possess the ability to describe a defect visually as well as verbally and b) ensure that the patient and …


Computer Simulation And Human Experiment On The Laplacian Electrocardiogram (Ecg), Ting Chen Jul 2007

Computer Simulation And Human Experiment On The Laplacian Electrocardiogram (Ecg), Ting Chen

Doctoral Dissertations

The electrocardiogram (ECG) provides useful global temporal assessment of cardiac activity, but has limited spatial capabilities. Laplacian electrocardiogram (LECG) and body surface Laplacian mapping (BSLM), improvements over ECG provides high spatiotemporal distributed information about cardiac electrical activation.

This project was divided into two parts: computer simulation and human experiment. In the computer simulation, a comparison of the performance of the tripolar and bipolar as well as spline LECG and BSLMs for localizing and imaging the cardiac electrical activation has been investigated. A simple planar surface model and a simplified eccentric heart-torso sphere-cylinder homogeneous volume conductor model were developed. Multiple dipoles …


Development And Analysis Of An Internet Browsing Utilizing The Overscan Technique For Persons With Physical Disabilities, Patrick Paul Clerkin Jul 2007

Development And Analysis Of An Internet Browsing Utilizing The Overscan Technique For Persons With Physical Disabilities, Patrick Paul Clerkin

Doctoral Dissertations

Persons with a severe disability often use scanning as an indirect selection technique for operating augmentative and alternative communication aids and computer access. For information that can be organized in advance, including lists of communication elements such as words and phrases, users often employ rate enhancing scanning methods like the row-column scanning technique. However, row-column scanning requires selection elements to be grouped into defined rows and columns, and therefore does not work well with Internet browsing due to the non-grouped layout of HTML pages.

This work attempts to develop an improved scanning technique for Internet browsing by designing interfaces to …


In Vivo Quantitation Of Rare Circulating Tumor Cells By Multiphoton Intravital Flow Cytometry, Wei He, Haifeng Wang, Lynn C. Hartmann, Ji-Xin Cheng, Phillip S. Low Jul 2007

In Vivo Quantitation Of Rare Circulating Tumor Cells By Multiphoton Intravital Flow Cytometry, Wei He, Haifeng Wang, Lynn C. Hartmann, Ji-Xin Cheng, Phillip S. Low

Other Nanotechnology Publications

Quantitation of circulating tumor cells (CTCs) constitutes an emerging tool for the diagnosis and staging of cancer, assessment of response to therapy, and evaluation of residual disease after surgery. Unfortunately, no existing technology has the sensitivity to measure the low numbers of tumor cells (< 1 CTC per ml of whole blood) that characterize minimal levels of disease. We present a method, intravital flow cytometry, that noninvasively counts rare CTCs in vivo as they flow through the peripheral vasculature. The method involves i.v. injection of a tumor-specific fluorescent ligand followed by multiphoton fluorescence imaging of superficial blood vessels to quantitate the flowing CTCs. Studies in mice with metastatic tumors demonstrate that CTCs can be quantitated weeks before metastatic disease is detected by other means. Analysis of whole blood samples from cancer patients further establishes that human CTCs can be selectively labeled and quantitated when present at approximate to 2 CTCs per ml, opening opportunities for earlier assessment of metastatic disease.


Fabrication Of Ankle-Foot Orthoses Using Selective Laser Sintering Technology, Allison Kinney, M. C. Faustini, Richard R. Neptune, R. H. Crawford, S. J. Stanhope Jul 2007

Fabrication Of Ankle-Foot Orthoses Using Selective Laser Sintering Technology, Allison Kinney, M. C. Faustini, Richard R. Neptune, R. H. Crawford, S. J. Stanhope

Mechanical and Aerospace Engineering Faculty Publications

Passive dynamic ankle-foot orthoses (AFOs) are often prescribed to improve gait performance for those with various neuromuscular disorders. Designs and materials used for AFOs range from simple polypropylene braces to advanced custom carbon fiber dynamic AFOs that passively store and release mechanical energy during gait. AFO designs vary in the shape and length of the foot component as well as the stiffness and length of the tibial component, depending on the desired functional outcomes. However, the current fabrication technology is not ideally suited for refined customization of AFO characteristics to optimize performance, or for rapid lowcost, high volume manufacturing and …


Development And Analysis Of A Software Package To Quantify In Vivo Polyethylene Wear After Total Hip Arthroplasty, Allison Kinney, Catherine G. Ambrose Jul 2007

Development And Analysis Of A Software Package To Quantify In Vivo Polyethylene Wear After Total Hip Arthroplasty, Allison Kinney, Catherine G. Ambrose

Mechanical and Aerospace Engineering Faculty Publications

Since the first total hip arthroplasty (THA) in 1938, THA evolved and developed into one of the major concentrations of orthopaedic research. The typical hip implant device used today incorporates a femoral and an acetabular component that serve to replicate the anatomical and mechanical functions of the natural hip joint. However, several problems exist that can effect the function of the implant device. Wear in the polyethylene liner of the acetabular component of the total hip replacement device is known as one of the major factors that affects the longevity of total hip replacement devices. Both manual and computer-aided techniques …


Water Erosion Prediction Project (Wepp): Development History, Model Capabilities, And Future Enhancements, Dennis C. Flanagan, John E. Gilley, Thomas G. Franti Jul 2007

Water Erosion Prediction Project (Wepp): Development History, Model Capabilities, And Future Enhancements, Dennis C. Flanagan, John E. Gilley, Thomas G. Franti

Department of Agricultural and Biological Systems Engineering: Faculty Publications

The Water Erosion Prediction Project (WEPP) was initiated in August 1985 to develop new‐generation water erosion prediction technology for use by federal action agencies involved in soil and water conservation and environmental planning and assessment. Developed by the USDA‐ARS as a replacement for empirically based erosion prediction technologies, the WEPP model simulates many of the physical processes important in soil erosion, including infiltration, runoff, raindrop and flow detachment, sediment transport, deposition, plant growth, and residue decomposition. The WEPP project included an extensive field experimental program conducted on cropland, rangeland, and disturbed forest sites to obtain data required to parameterize and …


Simulations Of Intracellular Calcium Release In Response To High-Intensity, Ultrashort Electric Pulse, Anh Nguyen Jul 2007

Simulations Of Intracellular Calcium Release In Response To High-Intensity, Ultrashort Electric Pulse, Anh Nguyen

Electrical & Computer Engineering Theses & Dissertations

Calcium modulation is an important signaling process and could even contribute to cell apoptosis through ionic-induced perturbations in trans-membrane potential at the mitochondria. In this research, the numerical study constitutes a first step in quantitatively probing the time- and spatially-dependent modulation of calcium dynamics through the application of external electrical fields. The research uses both widely accepted deterministic continuum and discrete stochastic intracellular calcium models coupling with external electric field, with a focus on high-intensity ultrashort pulse electrical field.

For deterministic continuum intracellular calcium models with electric field assisted, numerical simulations for electrically induced, intra-cellular calcium-release from the endoplasmic reticulum …


Parallel Facilitatory Reflex Pathways From The Foot And Hip To Flexors And Extensors In The Injured Human Spinal Cord, Maria Knikou, Elizabeth Kay, Brian D. Schmit Jul 2007

Parallel Facilitatory Reflex Pathways From The Foot And Hip To Flexors And Extensors In The Injured Human Spinal Cord, Maria Knikou, Elizabeth Kay, Brian D. Schmit

Biomedical Engineering Faculty Research and Publications

Spinal integration of sensory signals associated with hip position, muscle loading, and cutaneous sensation of the foot contributes to movement regulation. The exact interactive effects of these sensory signals under controlled dynamic conditions are unknown. The purpose of the present study was to establish the effects of combined plantar cutaneous afferent excitation and hip movement on the Hoffmann (H) and flexion reflexes in people with a spinal cord injury (SCI). The flexion and H-reflexes were elicited through stimulation of the right sural (at non-nociceptive levels) and posterior tibial nerves respectively. Reflex responses were recorded from the ipsilateral tibialis anterior (TA) …


Elastic Modulus Of Bone Using Ultrasonic Testing, Lanny Griffin, Victor Yu Jun 2007

Elastic Modulus Of Bone Using Ultrasonic Testing, Lanny Griffin, Victor Yu

Biomedical Engineering

No abstract provided.


Biomedical Engineering Virtual Circuit Simulation Laboratories, Robert B. Szlavik Jun 2007

Biomedical Engineering Virtual Circuit Simulation Laboratories, Robert B. Szlavik

Biomedical Engineering

Circuit simulators, such as SPICE (Simulation Program with Integrated Circuit Emphasis) are useful tools that can enhance the educational experience of students in many subject areas within a biomedical engineering curriculum. Courses on biomedical instrumentation are venues for which virtual laboratory experiments, using circuit simulators, can be readily developed. The instructor can use the circuit simulation platform to illustrate relatively complex concepts, such as differential amplification, which have wide applicability to biomedical instrumentation. More advanced courses that focus on the physiology of excitable cells or neural modeling and simulation are also venues for which circuit simulators may be applied to …


Biomedical Engineering Simulation Using Visual Basic Macros In Micrsoft Excel, Lanny Griffin, Robert Crockett Jun 2007

Biomedical Engineering Simulation Using Visual Basic Macros In Micrsoft Excel, Lanny Griffin, Robert Crockett

Biomedical Engineering

No abstract provided.


Biomaterials Screening Experiment Using Sessile Drop Contact Angles, Lanny Griffin Jun 2007

Biomaterials Screening Experiment Using Sessile Drop Contact Angles, Lanny Griffin

Biomedical Engineering

No abstract provided.


Temporal Changes In Nutrient Transport Following Land Application Of Manure, John E. Gilley, Eghball Bahman, D. B. Marx Jun 2007

Temporal Changes In Nutrient Transport Following Land Application Of Manure, John E. Gilley, Eghball Bahman, D. B. Marx

Department of Agricultural and Biological Systems Engineering: Presentations and White Papers

Little information is currently available concerning temporal changes in nutrient transport following the addition of manure to cropland areas. This study was conducted to measure nutrient transport in runoff as affected by tillage and time following the application of beef cattle or swine manure to a site on which corn [Zea mays (L.)] was grown. Rainfall simulation tests were initiated 4, 32, 62, 123, and 354 days following land application. Three 30-min simulated rainfall events, separated by 24-hour intervals, were conducted at an intensity of approximately 70 mm hr-1. Dissolved phosphorus (DP), particulate phosphorus (PP), total phosphorus (TP), NO3-N, …


Effect Of Overland Flow Rate On Nutrient Transport From Land Application Areas, John E. Gilley, William F. Sabatka, Bahman Eghball, David B. Marx Jun 2007

Effect Of Overland Flow Rate On Nutrient Transport From Land Application Areas, John E. Gilley, William F. Sabatka, Bahman Eghball, David B. Marx

Department of Agricultural and Biological Systems Engineering: Presentations and White Papers

Little information is currently available concerning the effects of varying flow rate on nutrient transport by overland flow. The objective of this study was to measure the effects of overland flow rate on nutrient transport following the application of beef cattle or swine manure to plots containing 0, 2, 4, or 8 Mg ha-1 of corn residue. After addition of residue materials to 0.75 m wide x 2.0 m long plots, beef cattle or swine manure was added and the plots were then either disked or maintained in a no-till condition. Three 30-min simulated rainfall events, separated by 24-hour …


Moldboard Plowing Following Compost Application Significantly Reduces Nutrient Transport, John E. Gilley, Bahman Eghball, David B. Marx Jun 2007

Moldboard Plowing Following Compost Application Significantly Reduces Nutrient Transport, John E. Gilley, Bahman Eghball, David B. Marx

Department of Agricultural and Biological Systems Engineering: Presentations and White Papers

The excessive application of manure on cropland areas can cause nutrients to accumulate near the soil surface and increase nutrient transport by overland flow. Inverting soils with high surface nutrient content could reduce runoff nutrient transport. This study was conducted to measure the effects of moldboard plowing on the redistribution of nutrients within the soil profile and nutrient transport by overland flow. Composted beef cattle manure was applied at dry weights of 0, 68, 105, 142, and 178 Mg ha-1 to a silty clay loam soil and then incorporated by disking. Selected plots were moldboard plowed 244 days later …


Runoff Nutrient Concentrations Following Manure Application As Affected By Crop Residue, John E. Gilley, Jeffrey Nicolaisen, Eghball Bahman, David B. Marx Jun 2007

Runoff Nutrient Concentrations Following Manure Application As Affected By Crop Residue, John E. Gilley, Jeffrey Nicolaisen, Eghball Bahman, David B. Marx

Department of Agricultural and Biological Systems Engineering: Presentations and White Papers

Manure is applied to cropland areas managed under diverse conditions resulting in varying amounts of residue cover. The objective of this study was to measure the effects of crop residue on nutrient concentrations in runoff from areas where beef cattle or swine manure were recently applied but not incorporated. Plots 0.75 m wide by 2 m long were established at the study site. Existing residue materials were removed, and corn, soybean, or winter wheat residue was added at rates of 2, 4, or 8 Mg ha-1. Manure was applied at rates required to meet estimated annual nitrogen requirements for corn. …


Microwave Pretreatment Of Switchgrass To Enhance Enzymatic Hydrolysis, Deepak R. Keshwani, Jay J. Cheng, Joseph C. Burns, Laigeng Li, Vincent Chiang Jun 2007

Microwave Pretreatment Of Switchgrass To Enhance Enzymatic Hydrolysis, Deepak R. Keshwani, Jay J. Cheng, Joseph C. Burns, Laigeng Li, Vincent Chiang

Department of Agricultural and Biological Systems Engineering: Presentations and White Papers

Switchgrass is a promising lignocellulosic biomass for fuel-ethanol production. However, pretreatment of lignocellulosic materials is necessary to improve its susceptibility to enzymatic hydrolysis. The objectives of this study were to examine the feasibility of microwave pretreatment to enhance enzymatic hydrolysis of switchgrass and to determine the optimal pretreatment conditions. Switchgrass samples immersed in water, dilute sulfuric acid and dilute sodium hydroxide solutions were exposed to microwave radiation at varying levels of radiation power and residence time. Pretreated solids were enzymatically hydrolyzed and reducing sugars in the hydrolysate were analyzed. Microwave radiation of switchgrass at lower power levels resulted in more …


Department Of Biological Systems Engineering Newsletter, Volume 3, Issue 1, June 2007 Jun 2007

Department Of Biological Systems Engineering Newsletter, Volume 3, Issue 1, June 2007

BSE Department Magazine

Contents:
Award Winning Academic Advisor
Hall of Fame 2007 Leslie W. Jochens, P.E. Leader in the Irrigation Industry
From the Department Head
John Deere Dealership Management Banquet
Alumni Profiles: Mike Henry
The Incredible, Edible Vehicle Competition
Graduation
December 2006 Graduates
May 2007 Graduates
Undergraduate Creative Activities and Research Experiences—UCARE
Honors Convocation
In Memoriam
Alumni News
Faculty News
Comings and Goings


Simulated Effects Of Marathon Training On Bone Density, Remodeling, And Microdamage Accumulation Of The Femur, Scott J. Hazelwood, Alesha B. Castillo Jun 2007

Simulated Effects Of Marathon Training On Bone Density, Remodeling, And Microdamage Accumulation Of The Femur, Scott J. Hazelwood, Alesha B. Castillo

Biomedical Engineering

Stress fractures are mechanically induced injuries resulting from fatigue damage to bone due to repetitive loading and are common injuries occurring in runners. In this study, we used computer simulations of marathon training programs to examine the effects of endurance running on femoral density, remodeling, and microdamage accumulation. Simulated remodeling activity increased in the femoral neck and proximal cortex and predicted microdamage increased in all regions examined after 16 weeks for each program. Daily running for three years produced more microdamage than the advanced training schedule over the same time period. Areas of high remodeling and damage corresponded to clinically …


Co-Production Of Chemical And Energy Products From Distillers Grains Using Supercritical Fluid Extraction And Thermochemical Conversion Technologies, Lijun Wang, Ajay Kumar, Curtis L. Weller, David D. Jones, Milford A. Hanna Jun 2007

Co-Production Of Chemical And Energy Products From Distillers Grains Using Supercritical Fluid Extraction And Thermochemical Conversion Technologies, Lijun Wang, Ajay Kumar, Curtis L. Weller, David D. Jones, Milford A. Hanna

Department of Agricultural and Biological Systems Engineering: Presentations and White Papers

Dry-grind technology has become the dominant method for ethanol production. During drygrind ethanol production, roughly one-third of the dry grain mass resides in the dried distillers grains with solubles (DDGS) as by-products (i.e., ∼0.8 kg/L ethanol). The energy content residing in the 0.8 kg DDGS is about 20 MJ, compared to the consumption of 1 MJ electricity and 10 MJ thermal energy for production of each liter of ethanol. A sequential supercritical fluid process with solvents including carbon dioxide, water and ethanol was used to recover high-value chemicals from DDGS. Thermochemical conversion methods were used to convert the DDGS residue …


Early Investment In Soil Conservation Research Continues To Provide Dividends, John E. Gilley, D. C. Flanagan Jun 2007

Early Investment In Soil Conservation Research Continues To Provide Dividends, John E. Gilley, D. C. Flanagan

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Current soil conservation programs are built upon an established research legacy. Hugh H. Bennett, chief of the USDA Soil Conservation Service from 1935 to 1951, was instrumental in the establishment of a network of 35 soil conservation experiment stations (SCES). Research projects were initiated at the SCES in the 1930s to investigate the principal factors causing erosion and to identify the most effective and practical methods of controlling soil loss from agricultural areas. Information obtained from the SCES, and selected other locations, was assembled at the National Runoff and Soil Loss Data Center (NRSLDC) established on the campus of Purdue …


Preliminary Work On The Development Of A Novel Detection Method For Osteoporosis, P. Moran, Mark R. Towler, S. Chowdhury, J. Saunders, M. J. German, N. S. Lawson, H. M. Pollock, I. Pillay, D. Lyons Jun 2007

Preliminary Work On The Development Of A Novel Detection Method For Osteoporosis, P. Moran, Mark R. Towler, S. Chowdhury, J. Saunders, M. J. German, N. S. Lawson, H. M. Pollock, I. Pillay, D. Lyons

Chemical and Biochemical Engineering Faculty Research & Creative Works

Osteoporosis affects both the organic and mineral phases of bone resulting in a decrease in resistance to fracture. Dual x-ray absorptiometry (DEXA) scans are used for diagnosing osteoporosis, which is conventionally characterized by a decrease in mineral density. Unfortunately, some patients who suffer osteoporotic fractures have normal bone density, because both the organic and the mineral phase are affected. However, there are currently no methods of evaluating the health of the organic phase. Patients undergoing treatment for osteoporosis have reported hardening of their fingernails. As the properties of nail and bone may be linked in a comparable, measurable way, this …


Central And Peripheral Autonomic Influences : Analysis Of Cardio-Pulmonary Dynamics Using Novel Wavelet Statistical Methods, Anne Marie Petrock May 2007

Central And Peripheral Autonomic Influences : Analysis Of Cardio-Pulmonary Dynamics Using Novel Wavelet Statistical Methods, Anne Marie Petrock

Dissertations

The development and implementation of novel signal processing techniques, particularly with regard to applications in the clinical environment, is critical to bringing computer-aided diagnoses of disease to reality. One of the most confounding factors in the field of cardiac autonomic response (CAR) research is the influence of the coupling of respiratory oscillations with cardiac oscillations.

This research had three objectives. The first was the assessment of central autonomic influence over heart rate oscillations when the pulmonary system is damaged. The second was to assess the link between peripheral and central autonomic control schema by evaluating the heart rate variability (HRV) …


Automatic Registration And Segmentation Of Abdominal Images And Detection Of Pancreatic Cancer, Girish Kumar Maniprasad May 2007

Automatic Registration And Segmentation Of Abdominal Images And Detection Of Pancreatic Cancer, Girish Kumar Maniprasad

Theses

Localized and detailed analyses of 3D abdominal images obtained through different imaging modalities help greatly in determining the progression of a disease or for postoperative treatment / evaluation. However, such analyses become difficult and sometimes unfeasible due to the effects of patient motion and breathing. This is particularly evident during analysis of the pancreas for cancer, due to its proximity to other intra-abdominal organs. Within subject registration thus becomes imperative for pathological analysis of pancreatic cancer. An intensity-based, global image registration algorithm was developed in the present work, for registration of pancreatic abdominal images. The registration algorithm was automatic and …