Biomedical Engineering and Bioengineering Commons^™

Development Of New Methods For Calculating Pressure And Energy Losses For Pumping Station Water Intakes, Faxriddin Jaylovovich Nosirov, Oleg Yakovlevich Glovatsky, Jurabek Abdyrahmon O'G'Li Urolov, Abduqodirkhon Samatkhonovich Abdullakhaev, Anvar Mamur Ugli Uzokov

Technical science and innovation

The aim of this study is to improve the efficiency of water resource management methods. Improvements to the water intake of the Karshi Main Canal are considered using calculations of pressure losses at the entry and exit of liquid into the flow, which differ from pressure losses in a stationary medium. The article considers some of the methods for using renewable energy sources, where the change in gravitational potential energy does not depend on the way of using energy and the operating scheme is a gravitational energy pump. The implementation of control and monitoring systems is necessary to ensure optimal …

Refinement Of Wind Speed Estimation At Turbine Hub Height Using Satellite Data And Regression Analysis Under Complex Terrain Conditions, Isroil Abriyevich Yuldoshev, Tulqin Rustamovich Jamolov, Sa'dullo Sayfiddin Ugli Fazliddinov, Jumanazar Farhodjon OʻGʻL Abdurashidov

Technical science and innovation

Reliable assessment of wind energy potential in regions characterized by complex terrain is often constrained by the limited availability of ground-based meteorological measurements. This study proposes an improved regression-based approach for refining wind speed estimates at the wind turbine hub height of 65 m using satellite-derived data from the NASA POWER database combined with a logarithmic vertical wind profile. The proposed methodology is validated using real operational data from a 750 kW wind power plant located in the mountainous Bostanlyk district of Uzbekistan for the period 2018–2021. The regression analysis demonstrates a strong linear relationship between the extrapolated wind speed …

A Platform For Acquiring And Classifying Low-Noise Electrocardiogram Signals For Applications In Cardiovascular Monitoring, Begmamat Berdimurodovich Dushanov, Narzullo Mamatov Dr.

Technical science and innovation

The early screening and continuous monitoring of cardiovascular diseases need effective acquisition and smart processing of electrocardiogram (ECG) signals. In this article, we introduce a compact platform designed for the acquisition of low-noise ECG signals and classification of the signals using a one-dimensional convolutional neural network (1D-CNN). Our compact platform consists of a low-noise analog front-end (AFE), including an instrumentation amplifier and a chain of analog filters, along with a data acquisition component designed to ensure effective suppression of baseline wander and high frequencies. Our compact platform consumes a low amount of power and can therefore be used for continuous …

Using Ai To Predict Energy Expenditure In Lower Limb Prosthesis Users, Nelly Diaz, Siem Hadish

Posters - 2026

• Computer vision has evolved from simple image classification and object detection to analyzing human motion and biomechanics (1). • CNN’s are usually focused on image classification, but, in this case, we are not asking the model if a person is walking. • Many real-world problems require regression: Predicting a continuous number like energy expenditure of walking is a complex task. • It is essential for Prosthetists to understand energy expenditure of their prosthetic patients (2). • An amputee may use 20-30% more energy to walk. • In this project, we developed an AI model to analyze human motion and …

Polymer Microstructures For Advanced Biomanufacturing, Tongyao Wu

LSU Doctoral Dissertations

With the continued growth of the biopharmaceutical industry, the demand for scalable, robust, and resource-efficient platforms for large-scale mammalian cell culture is amplified. Recent developments in microfluidic technology, such as precise control of the microenvironment, showed the potential to improve the performance of cell culture systems. However, constrained by scalability and operational efficiency, applying such approaches to large-scale cell culture and biopharmaceutical production presents challenges. This dissertation addresses these challenges through three independent but conceptually related technological developments. First, a roll-to-roll (R2R) fabrication process was developed for the scalable production of hollow microcarriers (HMCs). HMCs provide three-dimensional microenvironments suitable for …

Sensing Negative-Cone Rotational Diffusion Of Dipole-Like Emitters, Yuanxin Qiu, Kaizhi A. Nie, Matthew D. Lew

Electrical & Systems Engineering Publications and Presentations

Fluorescence anisotropy and single-molecule orientation-localization microscopy (SMOLM) are powerful techniques that quantify the rotational diffusion of dipole-like emitters, which is important for sensing molecular interactions and chemical environments at the nanoscale. Numerous theoretical and experimental studies have thoroughly characterized single-molecule rotations even when those rotations are much faster than the detector integration time. Here, we extend the theory of measuring rotational diffusion to situations where a single dipole rotates uniformly everywhere outside of an isotropic cone of a certain size, termed a negative cone. This scenario corresponds to negative fluorescence anisotropy 𝑟 and has been observed in emitters exhibiting strong …

Pid Control For Lower Limb Exoskeletons: A Framework Evaluation, Javlonbek Rakhmatillaev, Vytautas Bučinskas

Chemical Technology, Control and Management

This research provides a detailed guideline for implementing and evaluating Proportional Integral Derivative (PID) control frameworks in lower limb rehabilitation exoskeleton robotics. It examines the role of control systems within rehabilitation robotics, outlines the principles of PID control, describes exoskeleton architecture, explores applications of PID control, reviews optimization strategies, presents experimental validations, and considers future developments in the field. The proposed control framework incorporates aspects of mechanical design, actuator and sensor selection, and PID-based control algorithms, thereby promoting safe, accurate, and individualized rehabilitation support. Recommendations and effective guidance for future work are also presented.

Strategic Research On Rebco High-Temperature Superconducting Tapes, Tianping Ying, Dongliang Wang, Pengtao Yang, Lin Zhao, Zhongtang Xu, Ziyi Liu, Chao Yao, Yanwei Ma, Xingjiang Zhou, Jinguang Cheng, Zhong Fang

Bulletin of Chinese Academy of Sciences (Chinese Version)

High-temperature superconducting materials, represented by REBCO (REBa2Cu3O7-δ, where RE denotes rare-earth elements), are of significant strategic importance in fields such as energy, healthcare, and large-scale scientific facilities due to their excellent performance in the liquid nitrogen temperature range. However, they still face severe challenges in long-tape uniformity, production cost, and engineering reliability. Future development must shift toward a “material-processing-application” collaborative innovation model, aiming at enhancing flux pinning, optimizing the interfaces and mechanical properties of the multilayer structure, and integrating scalable and intelligent fabrication technologies to promote the low-cost and stable production of high-performance tapes. This study analyzes the core application …

Determining The Electric Field In A 10 Ns Pulsed Plasma In Fuel-Air Mixtures Using Efish, Md Ziaur Rahman, Christopher J. Kliewer, Brian D. Patterson, Chunqi Jiang

Bioelectrics Publications

Transient plasma ignition (TPI) utilizes non-equilibrium plasmas, produced by nanosecond high-voltage pulses, to improve lean-fuel combustion performance and reduce emission. It is known that the relatively high reduced electric field (E/N) in TPI plays an important role in generating energetic electrons and facilitating energy-efficient radical productions, resulting in reliable ignition for lean combustion. Determining the reduced electric field in the discharge is hence important for the understanding of the TPI process and ultimately allowing for the control of the plasma chemistry. This study reports spatiotemporally resolved measurements of the electric field (E) in a 10 ns pulsed plasma that is …

Federated And Explainable Spiking Neural Networks For Fair And Privacy-Preserving Nail Disease Diagnostics, Ch Pavani Reddy, Krishnanaik Vankdoth

Mansoura Engineering Journal

Automated nail disease diagnostics provide a non-invasive pathway for identifying underlying systemic health conditions; however, conventional centralized deep learning approaches often raise concerns related to privacy, fairness, and interpretability. Although the original NeuroNail-SNN framework demonstrated an energy-efficient and edge-ready diagnostic solution, its broader clinical adoption remained limited by unresolved trust, transparency, and ethical considerations. In this study, we propose the Federated and Explainable NeuroNail-SNN, which extends the original spiking neural architecture by integrating federated learning (FL), explainable artificial intelligence (XAI), fairness evaluation, and uncertainty quantification within a unified framework. Federated learning enables decentralized model training across hospitals and mobile clinics …

Beyond The Square Pulse: Waveform Shape, Eeg Correlates, And The Pursuit Of Natural Sensation In Tens, Jason Whitson

Honors Undergraduate Theses

This study investigates the relationship between electrical stimulus characteristics of shape and charge on evoked sensations and electroencephalogram (EEG) data during multi-waveform transcutaneous electrical nerve stimulation (TENS) of the median nerve. Neuromodulation methods have traditionally had little control over the location and quality of their associated evoked sensation (e.g., electric, vibration, touch). This experiment utilized five unique stimulus waveforms during TENS stimulation. EEG data were collected concurrently to provide an introductory objective measure of the neural responses underlying these sensory changes. Eleven participants completed three tasks (thresholding, super-threshold stimulation, two-alternative forced choice) using a two-electrode TENS approach. Stimulus waveforms were …

Linker-Free Gold-Sputtered Tapered Optical Fiber Plasmonic Sensors For High-Sensitivity Refractive Index Detection In Microfluidic Platforms, Erem Ujah, Gymama Slaughter

Center for Bioelectronics Publications

Gold-sputtered tapered optical fiber (Au-TOF) sensors were developed for high-sensitivity refractive-index (RI) detection using aqueous glucose standards spanning 1.33–1.41 RIU (0–50% w/v). The sensors were fabricated using a reproducible workflow combining flame-brushing tapering, plasma surface preparation, and rotational magnetron sputtering, enabling azimuthally uniform gold coatings without the use of thiol or sulfur linker chemistries. Two sputtering durations (24 s and 30 s) were investigated to examine thickness-dependent plasmonic coupling and sensing performance. Optical measurements were conducted using a broadband supercontinuum source and compact spectrometer within a 20 µL microfluidic sensing chamber. Increasing glucose concentration produced a monotonic decrease in transmission …

Comprehensive Mechatronic Design Methodology For 6-Dof Stationary Lower Limb Rehabilitation Exoskeleton Robot With Safety-Integrated Control Architecture, Javlonbek Rakhmatillaev Mr., Nodirbek Kimsanboyev Mr., Umidjon Takabaev Mr., Zafar Juraev Dr.

Chemical Technology, Control and Management

This paper presents the mechatronic design of a proposed six-degree-of-freedom (6-DOF) stationary lower limb rehabilitation exoskeleton (SLLRE) robot, developed through a comprehensive mechatronic design methodology that includes mechanical design, actuator and sensor selection, and the development of a control structure based on a safety-oriented control approach. The proposed 6-DOF SLLRE mechanical design introduces a comprehensive mechanical structure comprising bilateral hip, knee, and ankle joints, degrees of freedom, joint ranges of motion, human parameters for rehabilitation training, as well as the frames and structural elements of the proposed system. Furthermore, the selection of appropriate sensors, actuators, and control architecture for the …

Design And Development Of Biomimetic Hydrogel Interfaces For Enhanced Bioelectrical Signal Acquisition, Daniela Nikoloska

UNLV Theses, Dissertations, Professional Papers, and Capstones

Every second, human skin processes over one million sensory signals while maintaining properties such as electrical conductivity, mechanical adaptability, and regenerative capability that surpass all synthetic materials. Contemporary bioelectronic devices prove inadequate when contacting skin surfaces due to poor adhesion and electrical contact issues that prevent effective sensing. Despite advancements in wearable and bioelectronic technologies, current devices face major drawbacks when interfacing with human skin, particularly in maintaining firm adhesion, conformability, and low-noise electrical signal acquisition.

This research focuses on the development of a biomimetic hydrogel-based interface for bioelectronic sensing. Specifically, a hybrid hydrogel system composed of polydopamine (PDA)- doped …

Exploring Interactive Robotic Music Therapy Systems For Rehabilitation: A Survey Paper, Hector A. Salinas Gordillo

Discovery Undergraduate Interdisciplinary Research Internship

Interactive robotic music therapy introduces an innovative opportunity, where human guided musical interaction with robotic systems can create adaptive and engaging therapeutic experiences. This survey explores the current state of research at the intersection of robotics, music, and rehabilitation, focusing on emerging technologies such as human robot interaction methods and system designs that help enable real time, interactive music therapy.

Potential patient groups include individuals undergoing motor or cognitive rehabilitation, such as those recovering from stroke, living with Parkinson’s disease, cerebral palsy, or other motor impairments, as well as individuals with developmental disorders or limited mobility.

Traditional rehabilitation exercises may …

Impulse, Fall 2025, Jill Fier, Sierra Brown, Jerome J. Lohr College Of Engineering

Impulse (Jerome J. Lohr College of Engineering Publication)

2 | Faculty News
3 | SDSU Vet Hua to Head Civil Engineering
6 | Ad Lunam — To the Moon
10 | Building A Safety Culture
11 | Department News
12 | Surface Mount Technology Kickoff
14 | Construction Management Student, Volleyball Player Building Success Piece by Piece
16 | Student Awards, Honors
18 | Student Competition Results
20 | NASA Win Opens Doors for New Product Development Order
22 | SDSU Engineering Student Tabbed as Noblereach Fellow
26 | Knabach Award Recipient from Apprentice Lineman to Company President
28 | Metzger Create Faculty Endowment for SDSU Engineering
30 …

Optimizing Beer Fermentation Through Intelligent Control, Azizbek Nodirbekovich Yusupbekov, Mirjalol Yusupov

Chemical Technology, Control and Management

This paper presents an intelligent control approach for optimizing the beer fermentation process using fuzzy logic and adaptive neuro-fuzzy inference systems. By incorporating multivariable inputs—temperature error and pH deviation—the proposed system effectively handles the nonlinear dynamics and biological variability inherent in fermentation. Simulation results demonstrate improved control accuracy, responsiveness, and robustness compared to conventional methods, making the approach suitable for integration in modern brewery automation systems.

A Pilot Study On Tissue Deformation Using An Integrated Sensor–Actuator Blood Collection Setup In Aquaculture (Salmo Salar), Ishrak Siddiquee, Md Ebne Al Ashad, Ahmed Hasnain Jalal

Electrical and Computer Engineering Faculty Publications

This pilot study presents a sensor–actuator setup designed to evaluate tissue deformation in Atlantic Salmon (Salmo salar) during needle insertion. The system integrates three types of low-cost, commercially available force sensors to capture force profiles and identify biomechanical events associated with tissue layer transitions. Controlled insertions were performed on a deceased specimen, and the resulting force data were analyzed to quantify insertion dynamics and estimate tissue deformation. A simulation model based on the recorded force values was developed to calculate stress distribution and deformation, which ranged from 0.001 µm to 8.4 µm and from 0.3 N/m2 to 4.9 N/m2, respectively. …

Single-Molecule Orientation And Localization Microscopy, Sophie Brasselet, Matthew D. Lew

Electrical & Systems Engineering Publications and Presentations

Single-molecule localization microscopy (SMLM) offers enhanced spatial resolution in optical microscopy, providing detailed insights into the spatial organization of proteins in cells at the nanoscale. Over the past decade, SMLM has progressively incorporated the capability to retrieve the orientations of single molecules using their polarized dipolar emission pattern. Here we explore recent advancements in single-molecule orientation and localization microscopy (SMOLM), which yields super-resolved images of molecular three-dimensional (3D) orientations, wobble and 3D positions. This advancement opens possibilities to explore the nanoscale organization and conformation of biological molecules as well as to monitor and design local 3D optical fields in nanophotonics. …

Predicting The Response Of Tendon-Driven Prosthetic Finger With Hyperelastic Joints, Lucas Gallup, Mohamed Trabia, Brendan O'Toole

Mechanical Engineering Faculty Research

Properly designed prosthetics hands can enhance the quality of life for those suffering from limb loss. Recently, 3D-printed prosthetic hands are becoming common. In these prostheses, fingers flex through the tendons that are activated by motion of the wrist. To provide spring action, thermoplastic polyurethane (TPU) hyperelastic joints are used to connect digits to each other as well as to the wrist. While these designs are common, no model for the relationship between tendon tension and joint flexion is available. This work has developed a quasi-static virtual work-based model to predict the relationship between tendon forces and the flexion of …

Sar Analog-To-Digital Converters For Point-Of-Care Biosensors: A Comparison, Eithar Alammari, Joud Alamro, Sara Alashwali, Ghadah S. Alyami, Aziza I. Hussein

Effat Undergraduate Research Journal

The SAR ADC, recognized for its low power consumption, moderate resolution, and satisfactory processing speed, stands as an ideal choice for ultra-low power biomedical applications. Recent efforts have been concentrated on enhancing the power efficiency of the SAR ADC sub-components through intricate refinements and innovative techniques. These efforts aim to minimize energy consumption without compromising the ADC's performance. Therefore, this paper aims to thoroughly examine various implementation approaches for the main components of the SAR ADC, highlighting their individual strengths, weaknesses, and limitations within wireless biomedical applications.

Developing Deep Learning Methods For Cognitive Impairment Detection Based On Non-Invasive Data, Muath Alsuhaibani

Electronic Theses and Dissertations

Cognitive impairment detection is on the rise to help reduce the burden of healthcare costs on institutions and individuals. Mild Cognitive Impairment (MCI) is an early stage of cognitive decline progressing to Alzheimer’s disease (AD) or AD-related Dementia (ADRD). Detecting the early stages of AD/ADRD is crucial for early interventions among older adults to mitigate cognitive decline over time. However, the current diagnostic methods are often costly and/or invasive, such as MRI and PET scans. Thus, the search for non-invasive and cost-effective screening tools for the early detection of cognitive impairment using speech, language, visual, and motor data is growing. …

Functional Biopolymers Applied To Sustainable Technologies In The Environment And Healthcare, Fengjie He

UNLV Theses, Dissertations, Professional Papers, and Capstones

Biodegradable polymeric materials (biopolymers) are naturally derived materials known for their excellent biocompatibility, biodegradability, sustainability, and versatile chemical functionality. They have attracted increasing attention in various applications as alternative to synthetic materials ranging from food packaging to tissue engineering. Meanwhile, with intrinsic advantages, biopolymers have also emerged as promising materials in addressing contemporary challenges in both biomedical and environmental fields. Motivated by the significant potential of biopolymers and the growing need for sustainable materials, my research focuses on the design and engineering of biodegradable polymers with novel modification methods and application directions. In this work, two representative biopolymers are selected: …

A Deep Learning Approach For Semantic Segmentation And Its Application On Ctc., Samir Farag Harb

Electronic Theses and Dissertations

This dissertation explores the modeling and analysis of medical images, focusing on the intricate task of colon segmentation and subsequent 3D reconstruction, which are critical steps in Computed Tomography Colonography (CTC) systems. The primary objective of this research is to develop precise segmentation approaches to enhance the accuracy of colon identification and reconstruction from abdominal CT scans. Three distinct segmentation approaches are proposed and evaluated: a Markov Random Field (MRF)-based approach, a convolutional neural network (CNN)-based deep learning (DL) approach, and a sequential episodic training with dual contrastive learning Approach (G-SET-DCL) that has a flavor of few-shot learning (FSL). To …

Ac Electric Fields Manipulate And Concentrate Dna Molecules On Electrodes, Akila Wijesinghe, Dharmakeerthi Nawarathna

Graduate Student Government Association Research Conference

Point-of-care (POC) electric field-based biosensors have emerged as a promising tool to detect early cancer biomarkers such as circulating tumor DNA (ctDNA), microRNA (miRNA), and proteins. To be effective in screening in clinical settings, these biosensors must be simple and easy to use. In this study, we have studied the manipulation of short DNA molecules suspended in a sessile drop to achieve this goal. Alternative current (AC) electric fields were used to polarize DNA molecules and produce dielectrophoretic (DEP) force on DNA molecules. DEP force is used to manipulate polarized DNA molecules towards the higher electric field gradients (toward the …

Advancements In Refreshable Braille Display Technology: A Comprehensive Survey, Maryam Etezad, Rajeev Joshi, Franceli L. Cibrian

Engineering Faculty Articles and Research

This paper provides a comprehensive mapping literature review of the advancements in refreshable Braille display (RBD) technology, which employs dynamically movable pins or dots to render Braille characters for individuals with blindness and visual impairment. This literature review, which includes 96 papers, aims to summarize the current evidence on six distinct types of RBDs: piezoelectric, electromagnetic, electroactive polymer (EAP), pneumatic, shape memory alloy (SMA), and microfluidic technologies. For each type, we discuss the underlying mechanisms, alongside the current trends and research opportunities. This comparative analysis aims to inform the selection of appropriate RBD technology based on specific user needs and …

A Smart System For Detecting Anatomic And Histological Symptoms Of Diseased Agricultural Plants, Rustam Baratov, Himola Sunnatillayeva, Alimardon Mamatovich Mustafoqulov

Chemical Technology, Control and Management

This study describes a novel agricultural plant disease detecting smart system, capable of handling measured plant body parameters and images received by high resolution camera at the same time. The proposed plant disease detection method is based on evaluation of the signals received by measured and controlled plant body physical parameters like resistance, temperature and capacitance of the plant stem and image processing. An analogue plant model based on an electrical circuit with distributed parameters was developed. In addition, in the article the block diagram of the smart system for the early detection of plant diseases, the circuit diagram, its …

The Interplay Of Accommodation And Oculomotor Vergence Within Young Adults With Binocularly Normal Vision And Typically-Occurring Convergence Insufficiency, Sebastian Fine

Dissertations

Concerted binocular coordination evoking oculomotor and refractive responses to visual stimuli are essential to daily function. Oculomotor dysfunctions can inhibit binocular responses to visually-near stimuli and have high comorbidities to accommodative dysfunctions. Three visual cues for inward (convergent) and outward (divergent) oculomotor movements, when presented concertedly create natural-viewing conditions: disparity- the binocular difference in light cast onto the fovea due to differing ocular perspectives, blur- the acuity of a visual target which stimulates accommodation, and proximal- the perceived distance of a visual stimuli based on size.

This study aims to quantitatively investigate oculomotor vergence and accommodation performances between individuals with …

Toward The Application Of Natural Language Processing In Electronic Health Record Analysis For Taxonomy Development, Latoya Mcdonald

All Dissertations

Electronic health records (EHRs) are pivotal resources for nurse practice because they increase the timeliness and reliability of patient information at the point of care and support access by multiple healthcare providers and the individual patients themselves. However, it is widely recognized that data extraction from EHRs is challenging due to the variability in the language used in clinical care notes and the lack of standardized terminology across healthcare systems. The broad objective of this dissertation is to develop taxonomy-based classification models for nursing care by applying feature engineering approaches to EHRs that include nursing care of ostomy patients following …

Deep Learning In Lung Cancer Pre- And Post-Radiation Therapy: Diagnosis Of Malignancy And Radiation-Induced Lung Injury From 3d X-Ray Ct., Benjamin Peter Veasey

Electronic Theses and Dissertations

Lung cancer remains the leading cause of cancer-related mortality worldwide, with early detection and accurate diagnosis being critical for improving patient outcomes. Additionally, the progression of Radiation-Induced Lung Injury (RILI) following Stereotactic Body Radiation Therapy (SBRT) for lung cancer presents a significant diagnostic challenge. This dissertation addresses these challenges by developing deep learning-based diagnostic tools for both pre-treatment lung nodule malignancy classification and post-treatment RILI identification using 3D X-ray CT imaging. The research is divided into two primary objectives. First, for lung nodule malignancy classification, we developed a biopsy-confirmed dataset, called NLSTx, to train and evaluate deep learning models while …