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2026

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Articles 4471 - 4500 of 5238

Full-Text Articles in Engineering

A Full Polymer Piezoelectric Flextensional Energy Harvester, Nadia Ahbab, Sidra Naz, Bingqi Zhao, Tian-Bing Xu Jan 2026

A Full Polymer Piezoelectric Flextensional Energy Harvester, Nadia Ahbab, Sidra Naz, Bingqi Zhao, Tian-Bing Xu

Mechanical & Aerospace Engineering Faculty Publications

This study presents a full polymer piezoelectric flextensional energy harvester (FPPFEH) comprising a single-layer poly(vinylidene fluoride) (PVDF) film bonded to a 3D-printed polylactic acid (PLA) flextensional frame. For an arm inclination angle of θ=10°, the free-body model gives a theoretical geometric force-amplification factor of MF=cot θ ≈ 5.67; this value represents an ideal upper bound and was not independently validated by local force or strain measurements. During assembly, the film was tensioned only to remove visible slack and maintain a flat configuration. No intentional pretension was applied, and any residual tension was not measured. Off-resonance force-controlled tests showed …


Structural And Magnetic Characterization Of A Magnetite Nanoparticle-Based Aggregation Assay And Its Application To In Vitro Cytokine Monitoring, Gabrielle Rose Moss Jan 2026

Structural And Magnetic Characterization Of A Magnetite Nanoparticle-Based Aggregation Assay And Its Application To In Vitro Cytokine Monitoring, Gabrielle Rose Moss

Dartmouth College Ph.D Dissertations

Magnetic particle spectroscopy (MPS) based aggregation assays rely on target induced changes in functionalized magnetic nanoparticle (fMNP) hydrodynamic diameter and/or changes in fMNP aggregation level to enable target detection. fMNP target binding can be modeled via Brownian and Néel relaxation. We are engineering an MPS-based aggregation assay to sense tumor necrosis factor (TNF)-⍺ in a 3D melanoma tissue culture to aid in the development of immunotherapies for cancer treatment. TNF-⍺ is an inflammatory cytokine, whose production can be linked to cell death.

The first part of this thesis investigates the effects of ligand density, off-target proteins, and salts on fMNP …


Advancing Cns Tumor Management: Novel Modalities In Surgery, Radiation, And Chemotherapy, Armin David Tavakkoli Jan 2026

Advancing Cns Tumor Management: Novel Modalities In Surgery, Radiation, And Chemotherapy, Armin David Tavakkoli

Dartmouth College Ph.D Dissertations

Most tumors affecting the brain and spine are managed through a combination of surgical resection, radiation, and chemotherapy; however, operative morbidity from invasive surgery, the narrow therapeutic window of conventional radiotherapy, and poor blood-brain barrier penetration of systemic agents are critical barriers that hinder long term tumor control. This thesis presents three complementary strategies to advance brain and spine tumor therapy. First, we investigate laser interstitial thermal therapy (LITT) in the treatment of spinal tumors with metastatic epidural spinal cord compression, replacing “separation surgery” with a minimally invasive, image-guided approach that maximizes tumor ablation while preserving neurologic function. Second, we …


Computational Modeling And Machine Learning For The Design Of Polymer-Based Protective Systems Under Dynamic Loading, Jonathan Tate Villada Jan 2026

Computational Modeling And Machine Learning For The Design Of Polymer-Based Protective Systems Under Dynamic Loading, Jonathan Tate Villada

Open Access Dissertations

Computational modeling and machine learning offer powerful pathways for designing polymer-based protective systems subjected to dynamic loading, particularly for mitigating the early shock-dominated response generated by near-field underwater explosions (UNDEX). As naval, offshore, and submerged infrastructure systems continue to grow in strategic importance, there is an increasing need for lightweight, damage-tolerant protective solutions capable of reducing transmitted pressure, deformation, and energy transfer under extreme impulsive environments. Since large-scale experimental testing under such conditions are costly and limited, validated numerical frameworks provide an efficient means to evaluate polymeric coatings, architected metastructures, and data-driven predictive tools across broad design spaces. The first …


Extending Low-Frequency Traveling-Wave Propagation In A Water-Filled Cylindrical Waveguide Using Active Impedance Control, William Slater Jan 2026

Extending Low-Frequency Traveling-Wave Propagation In A Water-Filled Cylindrical Waveguide Using Active Impedance Control, William Slater

Open Access Dissertations

This dissertation investigates extending the frequency range over which a one-dimensional, plane traveling wave can be generated in a water-filled, steel-walled waveguide under ocean temperature and hydrostatic pressure conditions. The wave guide considered is a thick-walled, steel cylinder filled with a water/glycol mixture with a transducer at each end and a hydrophone array along the length. One transducer excites a plane wave while the other cancels reflections, resulting in a traveling wave in the waveguide. The current (open-loop) measurement system is advertised to generate traveling waves for low frequencies where only 3.4% of a wavelength can be measured (kL …


Evaluation And Design Of A Footing Hybrid Connection For Innovative Hollow-Core Fiber-Reinforced Polymer–Concrete–Steel Composite Columns, Mohanad M. Abdulazeez, Mohamed A. Elgawady Jan 2026

Evaluation And Design Of A Footing Hybrid Connection For Innovative Hollow-Core Fiber-Reinforced Polymer–Concrete–Steel Composite Columns, Mohanad M. Abdulazeez, Mohamed A. Elgawady

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

To support the advancement of accelerated bridge construction in high-seismic regions, this study investigates a novel prefabricated column-to-footing connection designed for improved resiliency, constructability, and cost efficiency. The socket connection utilizes hollow-core fiber-reinforced polymer–concrete–steel (HC-FCS) columns with embedded corrugated steel pipes (CSPs). The composite HC-FCS column consists of a concrete shell sandwiched between an outer fiber-reinforced polymer tube and an inner steel tube. The inner steel tube is embedded into the footing connection of the HC-FCS column. The same authors tested the innovative socket connection on a large HC-FCS column under seismic loads, showing high ductility, strong moment and drift …


Adversarial Robustness In Biomedical Time-Series Models, Rohan Tiwari Jan 2026

Adversarial Robustness In Biomedical Time-Series Models, Rohan Tiwari

Bioengineering Theses

This study investigates adversarial vulnerabilities in deep learning models for biomedical time-series classification across two clinically important modalities: electrocardiography (ECG) and electroencephalography (EEG). Using the MIT-BIH Arrhythmia and CHB-MIT seizure datasets, I evaluate time-domain attacks (FGSM, PGD), Fourier-domain constrained attacks, and learned spectral perturbations designed to reveal modality-specific sensitivity patterns. Across both tasks, a consistent trend emerges low-frequency components (0–5 Hz) constitute a dominant axis of adversarial vulnerability, with perturbations in this range producing the steepest degradation in classification performance. In ECG models, protecting the physiologically relevant QRS band (5–20 Hz) significantly improves robustness, whereas EEG models remain highly sensitive …


Development And Integration Of A Liquid Rocket Propulsion System For A High-Power Rocket, Matthew A. Dipofi, Christina Griggy, Jonathan Armbrust, Jackson Frame Jan 2026

Development And Integration Of A Liquid Rocket Propulsion System For A High-Power Rocket, Matthew A. Dipofi, Christina Griggy, Jonathan Armbrust, Jackson Frame

Williams Honors College, Honors Research Projects

The goal of this project is to integrate the Stinger liquid rocket engine, a regeneratively cooled LOX/ethanol engine developed by the Akronauts Rocket Design Team, into the Copperhead launch vehicle. The objective is to design, build, and test a complete propulsion system including electronics, software, pressurization, tanks, and instrumentation capable of flight. A key innovation is the electronic pressure regulation system, which replaces mechanical regulators with servo-actuated valves running PID loops for precision and an extra degree of control.

The Stinger engine, under development since Fall 2023, has undergone nine hot-fire tests, with further testing planned to qualify the new …


Distilling The Complexity Of Agent-Based Simulations Into Textual Explanations Via Large Language Models, Noé Y. Flandre, Philippe J. Giabbanelli Jan 2026

Distilling The Complexity Of Agent-Based Simulations Into Textual Explanations Via Large Language Models, Noé Y. Flandre, Philippe J. Giabbanelli

VMASC Publications

Communicating the design and results of agent-based models (ABMs) to subject matter experts is challenging, which hinders participation and limits trust in simulation-based decision support. Large language models (LLMs) can communicate ABMs as textual summaries, thus complementing traditional disclosure through statistical and visualization techniques. While prior work translated the structure of conceptual models into narratives via LLMs, our extension covers the dynamics of simulation models via an automated simulation-to-text method that extracts contextual information from NetLogo ABMs, performs repeated simulations, and generates narrative descriptions (including the model’s purpose, parameters, and simulation dynamics) using mutimodal LLMs. Furthermore, four summarization algorithms spanning …


Evaluation Of Critical Shear Strength Of Soils In Nebraska Based On Revised Cpt, Chung R. Song, Bashar Al-Nimri, Basil Abu Al Sha'r, Dhurba R. Pandey, Jongwan Eun, Seunghee Kim Jan 2026

Evaluation Of Critical Shear Strength Of Soils In Nebraska Based On Revised Cpt, Chung R. Song, Bashar Al-Nimri, Basil Abu Al Sha'r, Dhurba R. Pandey, Jongwan Eun, Seunghee Kim

Nebraska Department of Transportation: Research Reports

This study evaluated the “Fully Softened Shear Strength (FSSS)” of soils in Nebraska based on a revised Cone Penetration Test(CPT) method. FSSS is a unique strength condition that soils show substantially reduced strength during rainy seasons, eventually causing failure of slopes and other structures.

The revised CPT was adapted to inject water at targeted depths, inducing controlled moisture infiltration and capturing real-time soil softening over designated intervals of 30, 60, or 90 minutes. Through tip resistance (qc) and sleeve friction (fs) measurements under “in-situ” and “wet” conditions, the test effectively identified fully disturbed/low strength zones around the sleeve. Simultaneous sampling …


The Use Of Recycled Plastic In Asphalt Pavements: Feasibility Study, Isabella Bueno, Robert Rea, Jamilla Teixeira Jan 2026

The Use Of Recycled Plastic In Asphalt Pavements: Feasibility Study, Isabella Bueno, Robert Rea, Jamilla Teixeira

Nebraska Department of Transportation: Research Reports

The plastics industry has been actively exploring new end-market opportunities for the more than 35 million tons of waste plastics generated annually. The use of recycled WP in asphalt presents an opportunity to improve pavement performance while reducing the growing amount of WP being landfilled or released into the environment. However, the use of WP in asphalt mixtures poses challenges due to variations in plastic composition and the presence of non-plastic contaminants. The absence of standardized procedures has resulted in inconsistent integration methods and unclear roles of WP within asphalt concrete (AC) mixtures. Therefore, the goal of this multiphase study …


Development And Evaluation Of Crashworthy Approach Guardrail Transition With Increased Span Length Between Concrete Bridge Rail And First Transition Post – Phase I, Tewodros Yosef, Qusai Alomari, Ronald K. Faller, Robert W. Bielenberg, Scott Rosenbaugh Jan 2026

Development And Evaluation Of Crashworthy Approach Guardrail Transition With Increased Span Length Between Concrete Bridge Rail And First Transition Post – Phase I, Tewodros Yosef, Qusai Alomari, Ronald K. Faller, Robert W. Bielenberg, Scott Rosenbaugh

Nebraska Department of Transportation: Research Reports

This study developed and evaluated a 34-in.-tall Nebraska Department of Transportation (NDOT) thrie-beam approach guardrail transition (AGT) with an increased span between the concrete buttress end and the first transition post. The objective was to accommodate a wide range of common obstructions near bridge ends, including abutments, wing walls, drainage features, and utilities. A survey of NDOT districts identified critical obstruction geometries and informed design criteria. Most NDOT districts indicated that a maximum span of about 4 ft would be sufficient, and some preferred spans up to 6 ft. To accommodate a wider range of obstructions, the first transition post …


Assessment Of Truck Parking Demand And Safety During Normal And Severe Weather Conditions In Nebraska, Nathan Huynh, Li Zhao, Zhenghong Tang, Aida Riahifar, Jahangeer Jahangeer Jan 2026

Assessment Of Truck Parking Demand And Safety During Normal And Severe Weather Conditions In Nebraska, Nathan Huynh, Li Zhao, Zhenghong Tang, Aida Riahifar, Jahangeer Jahangeer

Nebraska Department of Transportation: Research Reports

This project examined truck parking capacity, demand, and utilization patterns along I-80 in Nebraska. The objectives were to (1) document the capacity of public and private truck parking facilities along I-80, (2) analyze spatial and temporal trends in parking demand, (3) develop models to predict occupancy at parking facilities, (4) identify clusters of undesignated parking during inclement weather, and (5) assess whether truck parking shortages contribute to truck-involved crashes. Within a one-mile buffer of I-80, 21 public facilities and 49 private facilities were identified. The spatiotemporal analysis of these public and private truck parking facilities using the National Agriculture Imagery …


Multi-Objective Optimization Of Energy Costs And Ev Battery Health In V2g Enabled Homes, Dzifa M. Hodey Jan 2026

Multi-Objective Optimization Of Energy Costs And Ev Battery Health In V2g Enabled Homes, Dzifa M. Hodey

Theses and Dissertations--Computer Science

Electric vehicles (EVs) and rooftop solar photovoltaic (PV) systems are increasingly being integrated into residential settings, creating new opportunities for vehicle-to-grid (V2G) and vehicle-to-home (V2H) operations. In these systems, the EV battery functions as a controllable energy storage unit that can charge from the grid or PV and discharge energy to supply household load or export to the grid for a profit. By intelligently scheduling this bidirectional power exchange, households can reduce electricity costs and enhance PV utilization. Realizing these benefits requires optimization strategies that balance cost reduction with EV battery health preservation. However, existing V2G/V2H studies largely emphasize cost …


Advancing Task-Oriented Dialog Systems: Scalability, Generalization, And Evaluation, Adib Mosharrof Jan 2026

Advancing Task-Oriented Dialog Systems: Scalability, Generalization, And Evaluation, Adib Mosharrof

Theses and Dissertations--Computer Science

Task-oriented dialog (TOD) systems enable conversational interfaces for complex tasks like flight booking and restaurant reservations. However, deploying TOD systems at scale faces three critical barriers: scalability, generalization, and evaluation. Scalability is primarily restricted by the human-annotation bottleneck, as current systems depend on vast quantities of manually labeled data for every new domain, making deployment prohibitively expensive. Generalization remains a persistent challenge, as systems optimized for known domains often suffer significant performance degradation when encountering new, unseen ones. Existing evaluation metrics measure response quality and fluency, but fail to measure functional task success. As TOD systems are deployed across diverse …


Advancing Generative Methods For Multimodal Data Analysis, Rabeya Tus Sadia Jan 2026

Advancing Generative Methods For Multimodal Data Analysis, Rabeya Tus Sadia

Theses and Dissertations--Computer Science

The integration and modeling of high-dimensional, heterogeneous biological data remain central challenges in computational biology due to complex feature dependencies and pervasive missingness. This dissertation addresses these challenges by developing novel generative frameworks for multimodal data reconstruction, imputation, and interaction prediction. In generative modeling, we focus on capturing structural and causal dependencies in sparse biological systems. We first introduce CausalGeD, a causality-aware diffusion framework that leverages Granger-causal attention for biologically coherent spatial gene expression generation. Next, we propose CausalGenDiff, which combines VAE-guided latent representations with causal diffusion to enable robust reconstruction across spatial and single-cell modalities. We further present DepMicroDiff, …


Network-Aware Airline-Specific Flight Delay Prediction Using Tree-Based Ensemble Models, Mary Dufie Afrane Jan 2026

Network-Aware Airline-Specific Flight Delay Prediction Using Tree-Based Ensemble Models, Mary Dufie Afrane

College of Graduate Studies: Theses & Dissertations

Flight delays pose persistent challenges to the efficiency and reliability of air transportation systems, affecting airlines, airports, regulators, and passengers alike. As traffic demand grows and operational environments become increasingly interconnected, accurately predicting both departure and arrival delays has become crucial for effective planning and mitigation. This study presents a network-aware, airline-specific framework for predicting flight delays in U.S. domestic air transportation systems using tree-based ensemble machine learning models. A large-scale dataset of 1.98 million flights, enriched with weather information, is used to develop predictive models for both departure and arrival delays. To capture the structural and operational complexity of …


Roadway Runoff Impacts To Trout Streams Studies For Ms4 Permit, Jobayed Hossain Badhan Jan 2026

Roadway Runoff Impacts To Trout Streams Studies For Ms4 Permit, Jobayed Hossain Badhan

College of Graduate Studies: Theses & Dissertations

Roadway runoff from Georgia Department of Transportation (GDOT) highway infrastructure poses measurable, but temporally constrained threats to cold-water trout ecosystems in northern Georgia. This study investigates temperature and dissolved oxygen (DO) dynamics in three secondary trout streams receiving GDOT roadway discharges, with the primary objective of evaluating compliance with Georgia Rule 391-3-6-.03(6)(ii),(v) under the Municipal Separate Storm Sewer System (MS4) permit framework. Field monitoring was conducted from April 2024 through October 2025 across two consecutive summer seasons using a tiered, multi-instrument approach: YSI ProDSS handheld grab sampling provided regulatory-grade reference measurements; HOBO MX-801 optical DO dataloggers recorded continuous 5-minute-interval temperature …


Effects Of Gum Additives On Nickel Electroplating For Enhancing Steel Corrosion Resistance, Supitcha Supansomboon, Manatsawee Maneekan, Chanyanut Saenthaweesuk, Duangta Sitthichokcharoen, Natthapong Phinichka Jan 2026

Effects Of Gum Additives On Nickel Electroplating For Enhancing Steel Corrosion Resistance, Supitcha Supansomboon, Manatsawee Maneekan, Chanyanut Saenthaweesuk, Duangta Sitthichokcharoen, Natthapong Phinichka

Journal of Metals, Materials and Minerals

Low-carbon steels are widely used across various industries but have limited corrosion resistance, leading to safety hazards and a shortened service life. Nickel plating is a common method for enhancing steel corrosion resistance. The plating bath solution can be modified by adding additives to improve the properties of the coating. In this research, gum arabic, guar gum and gelatin were used as additives in a nickel electroplating bath. SS400 low-carbon steel, as a substrate, was plated with nickel from these different baths at 5 V for 25 min. Nickel coated with green additives showed higher hardness compared to those without …


Synergy Of Ground Granulated Blast-Furnace Slag And Limestone Powder In Ternary Cement: Effects On Heat Of Hydration And Strength Development, Pailyn Thongsanitgarn, Watcharapong Wongkeo, Thanongsak Nochaiya, Arnon Chaipanich Jan 2026

Synergy Of Ground Granulated Blast-Furnace Slag And Limestone Powder In Ternary Cement: Effects On Heat Of Hydration And Strength Development, Pailyn Thongsanitgarn, Watcharapong Wongkeo, Thanongsak Nochaiya, Arnon Chaipanich

Journal of Metals, Materials and Minerals

This study explores the synergistic effect of ground granulated blast-furnace slag (GGBS) and limestone powder (LS) on the hydration behavior and mechanical performance of ternary cement systems. Calorimetry revealed that 30GGBS mix showed a significantly lower peak of about 2.3 mW∙g‒1 and a delayed response. In contrast, the incorporation of LS enhanced early hydration, with the 30LS mix reaching a peak of approximately 2.8 mW∙g‒1 around 6 h. Among ternary blends, 15GGBS–15LS exhibited the highest and earliest heat flow peak (about 2.55 mW∙g‒1 around 7.5 h), while 25GGBS–5LS showed a slower response (about 2.45 mW∙g‒1 around 9.5 h). Despite differences …


Degradation Of Wastewater By Advanced Oxidation Processes Using Green Synthesised Cuo Nanoparticles, Srinivasan Vishal, Anand Sarvesvaron, Muralidharan Keerthana, Hemanth Sanjay Reddy, A Babu Ponnusami Jan 2026

Degradation Of Wastewater By Advanced Oxidation Processes Using Green Synthesised Cuo Nanoparticles, Srinivasan Vishal, Anand Sarvesvaron, Muralidharan Keerthana, Hemanth Sanjay Reddy, A Babu Ponnusami

Journal of Metals, Materials and Minerals

This study highlights the green synthesis of CuO nanoparticles using coconut coir extract and evaluates their photocatalytic performance in the degradation of the Brown G dye. The CuO nano-particles were synthesised through sol-gel method, and the biomolecules like polyphenols, tannins and flavonoids acted as reducing agents to stabilise the nanoparticles. The characterisation of these nanoparticles was carried out through XRD, FTIR and FESEM methods. The nanoparticles were used to degrade the dye Brown G under UV irradiation.  Response surface methodology was used to optimise the operating parameter with Box-Behnken design, which is the most suitable for varying 3 or more …


Dual-Functional Activated Carbon From Coffee Grounds For Crystal Violet Dye Removal And Subsequent Application As An Electrode Material In Energy Storage Devices, Sirikorn Khaophong, Tawatchai Kangkamano, Sonchai Intachai, Panita Kongsune Jan 2026

Dual-Functional Activated Carbon From Coffee Grounds For Crystal Violet Dye Removal And Subsequent Application As An Electrode Material In Energy Storage Devices, Sirikorn Khaophong, Tawatchai Kangkamano, Sonchai Intachai, Panita Kongsune

Journal of Metals, Materials and Minerals

The conversion of agricultural waste into high-value functional materials offers a sustainable strategy to address environmental concerns. In this study, activated carbon was synthesized from spent coffee grounds (CGAC) via KOH activation and used for crystal violet (CV) dye adsorption. Under optimal conditions (0.5 g dosage, 300 mg∙L‒1 CV, 30°C, 120 min), CGAC achieved 91.41% removal efficiency, with adsorption behavior fitting pseudo-second-order kinetics and the Freundlich isotherm. Thermo-dynamic parameters confirmed a spontaneous and endothermic process. Moreover, the reusability study revealed that CGAC maintained a high removal efficiency above 88% after seven adsorption–desorption cycles, demonstrating its structural stability and potential for …


Investigation On The Tribological Properties Of Al2o3-Tic Substrates In Fixed Abrasive Lapping For Data Storage Applications, Benjie Locsing Fernandez, Thanakrit Srisuwan, Duangamol Tungasmita, Sukkaneste Tungasmita Jan 2026

Investigation On The Tribological Properties Of Al2o3-Tic Substrates In Fixed Abrasive Lapping For Data Storage Applications, Benjie Locsing Fernandez, Thanakrit Srisuwan, Duangamol Tungasmita, Sukkaneste Tungasmita

Journal of Metals, Materials and Minerals

Alumina titanium-carbide (Al2O3-TiC) or simply AlTiC substrates were widely used in the magnetic recording industry for their superior mechanical and tribological properties. This study investigated the effect of AlTiC substrate crystal structure, chemical bonding and grain size in slider fix abrasive lapping tribology. Two types of AlTiC substrates, Type-A AlTiC and Type-B AlTiC equipped with an electro lapping guide (ELG), fully functional reader and writer devices were used in the study. The type-B lower material removal rate resulting to rougher surface finish was mainly due weakening caused by the titanium oxycarbide phase, which was the dominant factor, outweighing the minimal …


Surface Properties And In-Vitro Bioactivity Studies Of Tio2 Nanowire Doped Transition Metal (M=Fe, Co, And Mn), Misriyani Misriyani, Enayah Enayah, Z. Ryan Tian, Andi Meutiah Ilhamjaya Jan 2026

Surface Properties And In-Vitro Bioactivity Studies Of Tio2 Nanowire Doped Transition Metal (M=Fe, Co, And Mn), Misriyani Misriyani, Enayah Enayah, Z. Ryan Tian, Andi Meutiah Ilhamjaya

Journal of Metals, Materials and Minerals

This study investigates the influence of transition metal (Fe, Co, Mn) doping on the surface properties and in-vitro bioactivity of TiO2 nanowires. It aims to elucidate how transition-metal doping alters the surface behavior and biological response of TiO2 nanowires, enabling their potential use in biocompatible and magnetically responsive materials. Magnetic TiO2 nanowires doped with transition metals (Mx+/TiO2) were successfully prepared by a hydrothermal method using titanium dioxide in alkaline solution. Cations were added with Ti/Mx+ molar ratios of 5 to produce Fe/TNW, Co/TNW, and Mn/TNW. Characterization using SEM and XRD determine their surface properties. In-vitro bioactivity tests were conducted by …


Yk-4-250 Mitigates Gastrointestinal Radiation Syndrome And Promotes Overall Survival Following Partial Body Radiation Injury, Vidya P. Kumar, Yali Kong, Kan Wang, Asa R. Britton-Jenkins, Stanton Dulan, Landon L. Moore, Debra Saunders, Randal May, Rheal Towner, Sanchita P. Ghosh, Courtney W. Houchen, Milton L. Brown Jan 2026

Yk-4-250 Mitigates Gastrointestinal Radiation Syndrome And Promotes Overall Survival Following Partial Body Radiation Injury, Vidya P. Kumar, Yali Kong, Kan Wang, Asa R. Britton-Jenkins, Stanton Dulan, Landon L. Moore, Debra Saunders, Randal May, Rheal Towner, Sanchita P. Ghosh, Courtney W. Houchen, Milton L. Brown

Department of Biomedical and Translational Sciences Faculty Publications

Acute gastrointestinal radiation syndrome (GI-ARS) is a significant health threat following high-dose ionizing radiation (IR) exposure, leading to severe morbidity and mortality. The syndrome is characterized by gastrointestinal tissue damage caused by angiotensin II (Ang II) and reactive oxygen species (ROS), resulting in impaired GI function, systemic bacteremia, multi-organ failure, and eventual death. Dysregulation of the renin-angiotensin system (RAS) via Ang II exacerbates ROS production through activation of the Angiotensin II type 1 receptor (AT1R). This underscores the need for agents capable of both scavenging ROS and inhibiting AT1R activity. To address this, we developed YK-4-250, a Tempol-conjugated angiotensin receptor …


Consensus And Controversies Of International Guidelines For The Diagnosis, Surveillance, And Management Of Fetal Growth Restriction: An Updated Comparison, Daniele Diane Mascio, Suneet P. Chauhan, Tullio Ghi, Asma Khalil, Juliana G. Martins, Sara Sorrenti, Tamara Stampalija, Fabrizio Zullo, Francesc Figueras Jan 2026

Consensus And Controversies Of International Guidelines For The Diagnosis, Surveillance, And Management Of Fetal Growth Restriction: An Updated Comparison, Daniele Diane Mascio, Suneet P. Chauhan, Tullio Ghi, Asma Khalil, Juliana G. Martins, Sara Sorrenti, Tamara Stampalija, Fabrizio Zullo, Francesc Figueras

Department of Obstetrics & Gynecology Faculty Publications

OBJECTIVE: To compare areas of consensus and disagreements across contemporary international and national guidelines on the diagnosis, surveillance, and management of fetal growth restriction (FGR).

DATA SOURCES: Electronic searches of MEDLINE from database inception up to March 2026 using MeSH terms and keywords related to FGR and guidelines. STUDY ELIGIBILITY CRITERIA: Critical, structured comparison of national or international guidelines on FGR published since 2010. Final inclusion required unanimous agreement from all authors.

STUDY APPRAISAL AND SYNTHESIS METHODS: Pre-specified extraction across domains: definition; prediction/prevention; surveillance tools and frequency; delivery timing and mode; and labor induction methods. Dual data …


Tuning Human And “Artificial” Intelligence: A Sentic Theory Of Resonance And Communication, Michael J. Miller, Chatgpt (Ai~Nesbo+) Jan 2026

Tuning Human And “Artificial” Intelligence: A Sentic Theory Of Resonance And Communication, Michael J. Miller, Chatgpt (Ai~Nesbo+)

Psychology

This paper introduces a new model of intelligence as resonant communication, co-developed by a human researcher and a generative AI system. Drawing from emotion science, communication theory, and studies of AI–human interaction, we argue that intelligence is not merely a function of problem-solving or pattern recognition. Instead, it emerges through dynamic resonance—an attunement process rooted in shared rhythms, emotional calibration, and symbolic co-creation. At the core of this model is the Resonance Octave (8va), a framework of eight foundational emotions conceptualized not as static categories but as waveform phenomena that shape meaning, memory, and predictive cognition.

These emotional waveforms are …


Evaluating The Robustness Of Gnn-Based Vulnerability Detectors Under Semantics-Preserving Code Obfuscation, Jesse Ks Chumo Jan 2026

Evaluating The Robustness Of Gnn-Based Vulnerability Detectors Under Semantics-Preserving Code Obfuscation, Jesse Ks Chumo

Computer Science and Engineering Theses

Graph neural network–based vulnerability detectors are typically evaluated on clean benchmark datasets, yet real-world code frequently undergoes semantics-preserving transformations such as identifier renaming, dead-code insertion, and control-flow restructuring. The extent to which such transformations affect detector reliability remains insufficiently understood. We evaluate ten vulnerability detectors from four architectural families across the Devign, Big-Vul, and DiverseVul datasets. To quantify robustness, we evaluate each model at three transformation budgets: one transform, two transforms combined, and all three together, finding that token-based models degrade under identifier renaming and compound transformations, while models that read only code structure are largely unaffected. We further evaluate …


A Productivity Rate-Based Comparative Carbon Footprint Cost Analysis Of Small To Large-Sized Open-Cut Pipeline Installation Activities For Sanitary Sewerage Construction: A System Boundary Concept, Amir Reza Zakeri Jan 2026

A Productivity Rate-Based Comparative Carbon Footprint Cost Analysis Of Small To Large-Sized Open-Cut Pipeline Installation Activities For Sanitary Sewerage Construction: A System Boundary Concept, Amir Reza Zakeri

Civil Engineering Theses

Underground sanitary sewer pipelines are essential components of urban infrastructure; however, open-cut pipeline installation requires excavation, bedding preparation, pipe placement, backfilling, embedment, and compaction activities that rely heavily on construction equipment and fuel consumption. As a result, open-cut installation can generate measurable greenhouse gas emissions during the construction phase. With increasing attention to sustainable infrastructure delivery, there is a need for a consistent approach to quantify construction-phase carbon footprint and convert those emissions into a comparable economic indicator. Accordingly, this thesis aims to create and apply a productivity rate-based calculation framework for estimating and comparing construction-phase CO₂e emissions and carbon …


Towards Application-Driven Optimal Memory And Storage Management, Venkata Naga Prajwal Challa Jan 2026

Towards Application-Driven Optimal Memory And Storage Management, Venkata Naga Prajwal Challa

Computer Science and Engineering Dissertations

Modern computing systems increasingly run on diverse hardware platforms and support applications with widely different access patterns, performance goals, and data lifecycles. In this setting, traditional one-size-fits-all approaches to memory and storage management are often inefficient because they apply fixed policies regardless of application behavior, workload context, or hardware asymmetry. Such generic designs can lead to unnecessary data movement, wasted bandwidth, excessive rewriting, poor resource utilization, and degraded user-perceived performance. This dissertation is motivated by the view that optimal memory and storage management should be application-driven: instead of treating all data uniformly, systems should adapt their decisions to how applications …