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Articles 31 - 32 of 32
Full-Text Articles in Engineering
Evaluating Outer Segment Length As A Surrogate Measure Of Peak Foveal Cone Density, Melissa A. Wilk, Brandon M. Wilk, Christopher S. Langlo, Robert F. Cooper, Joseph Carroll
Evaluating Outer Segment Length As A Surrogate Measure Of Peak Foveal Cone Density, Melissa A. Wilk, Brandon M. Wilk, Christopher S. Langlo, Robert F. Cooper, Joseph Carroll
Biomedical Engineering Faculty Research and Publications
Adaptive optics (AO) imaging tools enable direct visualization of the cone photoreceptor mosaic, which facilitates quantitative measurements such as cone density. However, in many individuals, low image quality or excessive eye movements precludes making such measures. As foveal cone specialization is associated with both increased density and outer segment (OS) elongation, we sought to examine whether OS length could be used as a surrogate measure of foveal cone density. The retinas of 43 subjects (23 normal and 20 albinism; aged 6–67 years) were examined. Peak foveal cone density was measured using confocal adaptive optics scanning light ophthalmoscopy (AOSLO), and OS …
Lung Injury Pathways: Adenosine Receptor 2b Signaling Limits Development Of Ischemic Bronchiolitis Obliterans Organizing Pneumonia, John C. Densmore, Terry R. Schaid, Paul M. Jeziorczak, Meetha Medhora, Said H. Audi, Shraddha Nayak, John Auchampach, Melinda R. Dwinell, Aron M. Geurts, Elizabeth R. Jacobs
Lung Injury Pathways: Adenosine Receptor 2b Signaling Limits Development Of Ischemic Bronchiolitis Obliterans Organizing Pneumonia, John C. Densmore, Terry R. Schaid, Paul M. Jeziorczak, Meetha Medhora, Said H. Audi, Shraddha Nayak, John Auchampach, Melinda R. Dwinell, Aron M. Geurts, Elizabeth R. Jacobs
Biomedical Engineering Faculty Research and Publications
Purpose/Aim of the Study: Adenosine signaling was studied in bronchiolitis obliterans organizing pneumonia (BOOP) resulting from unilateral lung ischemia. Materials and Methods: Ischemia was achieved by either left main pulmonary artery or complete hilar ligation. Sprague–Dawley (SD) rats, Dahl salt sensitive (SS) rats and SS mutant rat strains containing a mutation in the A2B adenosine receptor gene (Adora2b) were studied. Adenosine concentrations were measured in bronchoalveolar lavage (BAL) by HPLC. A2A (A2AAR) and A2B adenosine receptor (A2BAR) mRNA and protein were quantified. Results: Twenty-four hours after unilateral PA …