Engineering Commons^™

Countercurrent Flowthrough Pretreatment Of Cellulosic Biomass, Véronique Archambault-Léger

Link Foundation Energy Fellowship Reports

The aim of my work as a Link Fellow was to develop an analytical framework incorporating fluid mechanical, thermodynamics and kinetic factors to determine the feasible domains of hot water FT pretreatment. I addressed the mechanical complexities of arranging a bed of biomass for FT configuration and analyzed the energy requirements, capital costs and sugar dilution in order to realize the advantages of FT pretreatment at scale.

Design And Synthesis Of Low-Bandgap Polymers For Organic Photovoltaic Applications, Letian Dou

Link Foundation Energy Fellowship Reports

This research at UCLA focused on the design and synthesis of novel conjugated polymers as the electron-donor material for photovoltaic devices. By careful molecular design both on the polymer backbone and the side chains, a series of low-bandgap conjugated polymers were synthesized for a variety of photovoltaic applications, including single junction and tandem polymer solar cells. In addition, the author designed and synthesized a novel higly perfect polymer single crystal material via a visible light triggered topochemical reaction. This kind of materials shows high potential for application in solar cells and transistors, which, the author believe, is a huge breakthrough …

Thorough Exploration Of Complex Environments With A Space-Based Potential Field, Kenealy Alina, Nicholas Primiano, Alex Keyes, Lyons Damian

Faculty Publications

Robotic exploration, for the purposes of search and rescue or explosive device detection, can be improved by using a team of multiple robots. Potential field navigation methods offer natural and efficient distributed exploration algorithms in which team members are mutually repelled to spread out and cover the area efficiently. However, they also suffer from field minima issues. Liu and Lyons proposed a Space-Based Potential Field (SBPF) algorithm that disperses robots efficiently and also ensures they are driven in a distributed fashion to cover complex geometry. In this paper, the approach is modified to handle two problems with the original SBPF …

Homing With Stereovision, Paramesh Nirmal, Damian Lyons

Faculty Publications

Visual Homing is a navigation method based on comparing a stored image of a goal location to the current image to determine how to navigate to the goal location. It is theorized that insects such as ants and bees employ visual homing techniques to return to their nest or hive, and inspired by this, several researchers have developed elegant robot visual homing algorithms. Depth information, from visual scale, or other modality such as laser ranging, can improve the quality of homing. While insects are not well equipped for stereovision, stereovision is an effective robot sensor. We describe the challenges involved …

Evaluation Of Parallel Reduction Strategies For Fusion Of Sensory Information From A Robot Team., Damian M. Lyons, Joseph Leroy

Faculty Publications

The advantage of using a team of robots to search or to map an area is that by navigating the robots to different parts of the area, searching or mapping can be completed more quickly. A crucial aspect of the problem is the combination, or fusion, of data from team members to generate an integrated model of the search/mapping area. In prior work we looked at the issue of removing mutual robots views from an integrated point cloud model built from laser and stereo sensors, leading to a cleaner and more accurate model. This paper addresses a further challenge: Even …

Leveraging Area Bounds Information For Autonomous Decentralized Multi-Robot Exploration, Tsungming Liu, Damian Lyons

Faculty Publications

This paper proposes a simple and uniform, decentralized approach to the problem of dispersing a team of robots to explore an area quickly. The Decentralized Space-Based Potential Field (D-SBPF) algorithm is a potential field approach that leverages knowledge of the overall bounds of the area to be explored. It includes a monotonic coverage factor in the potential field to avoid minima, realistic sensor bounds, and a distributed map exchange protocol. The D-SBPF approach yields a simple potential field control strategy for all robots but nonetheless has good dispersion and overlap performance in exploring areas with convex geometry while avoiding potential …

Performance Verification For Behavior-Based Robot Missions, Damian M. Lyons, Ron Arkin, Shu Jiang, Tsungming Liu, Paramesh Nirmal

Faculty Publications

Certain robot missions need to perform predictably in a physical environment that may have significant uncertainty. One approach is to leverage automatic software verification techniques to establish a performance guarantee. The addition of an environment model and uncertainty in both program and environment, however, means the state-space of a model-checking solution to the problem can be prohibitively large. An approach based on behavior-based controllers in a process-algebra framework that avoids state-space combinatorics is presented here. In this approach, verification of the robot program in the uncertain environment is reduced to a filtering problem for a Bayesian Network. Validation results are …

Bio-Oil And Biodiesel As Biofuels Derived From Microalgal Oil And Their Characterization By Using Instrumental Techniques, Dipesh Kumar, Bhaskar Singh, Kuldeep Bauddh, John Korstad

College of Science and Engineering Faculty Research and Scholarship

Microalgal oil has been a source for production of biofuels such as bio-oil and biodiesel. These two biofuels can be characterized quantitatively using advanced instrumentation techniques. Nile red fluorescence method, PAM fluorometry, NMR, GC/GC-MS, and FTIR are among the major techniques available for characterization and quantification of algal oil. NMR is a rapid and nondestructive analytical technique as it requires minimal sample preparation, and even one intact algal cell can be analyzed. It can also be used for continuous monitoring of cellular composition of algal culture. NMR can be used to monitor transesterification reaction and oxidation of lipids and biodiesel …

Online Auction-Based Relay Selection For Cooperative Communication In Cr Networks, Tao Jing, Fan Zhang, Wei Cheng, Yan Huo, Xiuzhen Cheng

Computer Science Publications

Cognitive radio and cooperative communication are two new network technologies. So, the combination of these two new technologies is a novel solution to solve the problem of spectrum scarcity. Two main challenges exist in the integration of cognitive radio and cooperative communication. First, there is a lack of incentives for the participating wireless devices to serve as relay nodes. Second, there is not an effective relay selection policy. In this paper, we propose an online auction-based relay selection scheme for cooperative communication in cognitive radio (CR) networks. Specifically, we design an auction scheme through adopting stopping theory. The proposed scheme …

Nanocuration Workflows: Establishing Best Practices For Identifying, Inputting, And Sharing Data To Inform Decisions On Nanomaterials, Christina M. Powers, Karmann A. Mills, Stephanie A. Morris, Fred Klaessig, Sharon Gaheen, Nastassja Lewinski, Christine Ogilvie Hendren

Chemical and Life Science Engineering Publications

There is a critical opportunity in the field of nanoscience to compare and integrate information across diverse fields of study through informatics (i.e., nanoinformatics). This paper is one in a series of articles on the data curation process in nanoinformatics (nanocuration). Other articles in this series discuss key aspects of nanocuration (temporal metadata, data completeness, database integration), while the focus of this article is on the nanocuration workflow, or the process of identifying, inputting, and reviewing nanomaterial data in a data repository. In particular, the article discusses: 1) the rationale and importance of a defined workflow in nanocuration, 2) the …

Generation Of Multicellular Tumor Spheroids With Microwell-Based Agarose Scaffolds For Drug Testing, Xue Gong, Chao Lin, Jian Cheng, Jiansheng Su, Hang Zhao, Tianlin Liu, Xuejun Wen, Peng Zhao

Chemical and Life Science Engineering Publications

Three dimensional multicellular aggregate, also referred to as cell spheroid or microtissue, is an indispensable tool for in vitro evaluating antitumor activity and drug efficacy. Compared with classical cellular monolayer, multicellular tumor spheroid (MCTS) offers a more rational platform to predict in vivo drug efficacy and toxicity. Nevertheless, traditional processing methods such as plastic dish culture with nonadhesive surfaces are regularly time-consuming, laborious and difficult to provide uniform-sized spheroids, thus causing poor reproducibility of experimental data and impeding high-throughput drug screening. In order to provide a robust and effective platform for in vitro drug evaluation, we present an agarose scaffold …

Transplantation Of Induced Pluripotent Stem Cells Alleviates Cerebral Inflammation And Neural Damage In Hemorrhagic Stroke, Jie Qin, Xun Ma, Haiyun Qi, Bo Song, Yanlin Wang, Xuejun Wen, Qing Mei Wang, Shilei Sun, Yusheng Li, Rui Zhang, Xinjing Liu, Haiman Hou, Guangming Gong, Yuming Xu

Chemical and Life Science Engineering Publications

Background

Little is known about the effects of induced pluripotent stem cell (iPSC) treatment on acute cerebral inflammation and injuries after intracerebral hemorrhage (ICH), though they have shown promising therapeutic potentials in ischemic stoke.

Methods

An ICH model was established by stereotactic injection of collagenase VII into the left striatum of male Sprague-Dawley (SD) rats. Six hours later, ICH rats were randomly divided into two groups and received intracerebrally 10 μl of PBS with or without 1×10⁶ of iPSCs. Subsequently, neural function of all ICH rats was assessed at days 1, 3, 7, 14, 28 and 42 after ICH. …

Genome-Scale Resources For Thermoanaerobacterium Saccharolyticum, Devin H. Currie, Babu Raman, Christopher M. Gowen, Timothy J. Tschaplinski, Miriam L. Land, Steven D. Brown, Sean F. Covalla, Dawn M. Klingeman, Zamin K. Yang, Nancy L. Engle, Courtney M. Johnson, Miguel Rodriguez, A Joe Shaw, William R. Kenealy, Lee R. Lynd, Stephen S. Fong, Jonathan R. Mielenz, Brian H. Davison, David A. Hogsett, Christopher D. Herring

Chemical and Life Science Engineering Publications

Background

Thermoanaerobacterium saccharolyticum is a hemicellulose-degrading thermophilic anaerobe that was previously engineered to produce ethanol at high yield. A major project was undertaken to develop this organism into an industrial biocatalyst, but the lack of genome information and resources were recognized early on as a key limitation.

Results

Here we present a set of genome-scale resources to enable the systems level investigation and development of this potentially important industrial organism. Resources include a complete genome sequence for strain JW/SL-YS485, a genome-scale reconstruction of metabolism, tiled microarray data showing transcription units, mRNA expression data from 71 different growth conditions or timepoints …

Grid Game: Developing A Java/Android Version For Increased Accessibility And Usability, Sean Amos, Patrick Sivils, Aidan Collins

Capstone Design Expo Posters

Objective: Idaho University has implemented a power grid simulator game as a teaching aid for students enrolled in their Resilient Control Systems course. The game was created in LabView and requires the user to download the LabView client, as well as install the Grid Game on their machine in order to play. Our goal is to recreate the Grid Game in a Java based web-browser format so that the game is more accessible and easy to use. By recreating the Grid Game in a format that can be played in browser, other universities, companies, and individuals will easily be able …

Smart Grid Network Simulation, Morgan Waser, Brandon Perkins, Benjamin Koppier

Capstone Design Expo Posters

Problem: In the coming years the United States is working to move towards a smarter electric grid. One that is more versatile and can adjust to different situations. To move forward with these from our current electric grid to the Smart Grid, simulations are needed to understand how the new grid is likely to behave in different situations.

Rationale: The importance of creating these simulations is to try and predict which topological set-ups are best for different kinds of scenarios as well as how the grid might behave under different circumstances. Once different situations are simulated, Smart Grid developers can …

Scientifically Defensible And Measurable Anti-Phishing Training, Josh Rymer, Chris Neville, Robert Hodges

Capstone Design Expo Posters

Problem: How can the effectiveness of a phishing attack be quantified and/or measured?

Applications: This project will provide a resource for Idaho National Labs to quantitavely evaluate the effectiveness of their security awareness program in regards to phishing attacks. In turn, it will aid them in hardening the human element of security at the research facility.

Approach: Our approach is to construct a fully functional phishing system where we can craft phishing emails, send emails, and place links that point to our web application. We hope to use this system to conduct an anonymous and non-malicious experiment. This data will …

Cybersecurity Vulnerabilities In The Smart Grid & Thermodynamical Properties Database Software, Abderrahmen Chouat, Shiyoon Joo, Jacob Holcombe

Capstone Design Expo Posters

Project Scope: Smart grid stability and issues/ challenges associated with coupling nuclear and renewable energy source will be researched. The changes we can expect in grid technology so the robustness and resilience could be further improved will be addressed. This projects will entail literature surveys and may involve running some simulation software and comparisons. Another aspect of the project will be focus on nuclear plant as part of the future smart grid stability challenge. Specifically, this part of the project will entail CFD modeling of zig-zag Printed Circuit compact heat exchanger and modeling it in MATLAB and seeing the difference …

Clover Care: Website And E-Marketing Development, Parker Bryant, Amber Elliott, Weston Kingery, Ervin Ramos

Capstone Design Expo Posters

Clover Care is a geographically diverse company with both caregivers and clients spread across multiple counties. Efficient resource management and communication is critical for such a broadly distributed company. Clover Care also expects to continue expanding its geographical service area, making a solution even more critical. Clover Care was interested in updating and expanding their existing website to address this need. The centralization provided by using a website allows caregivers, clients and their families, and managers a way to quickly and effectively communicate.

The primary Clover Care forms that were to be centralized included the caregiver timesheet, client case management …

Predator-Prey Game To Maintain Stable Fish Population For Ecotoxicological Studies, Jason Blondin, Catherine Halpern, Tyler Malkus

Capstone Design Expo Posters

With the state of the environment on the forefront of many minds today, it’s important for our society to be able to understand how we interact with our local ecosystems and the potential impacts we can cause. Creating computational simulations of these environments can help to predict the possible effects of different situations. The purpose of our project was to create a predator-prey simulation of different species of fish that could take into account different population management strategies and accurately reflect the waves that could be caused by the introduction of various chemicals into the fish’s environment.

In order to …

Church Hill Activities & Tutoring, Dhundi Acharya, Dhruvil Shah, Michael Mcalexander

Capstone Design Expo Posters

Problem Statement: Church Hill Activities and Tutoring ( CHAT ), a non-profit organization which invests in the lives of Richmond’s most at-risk children by establishing strong connections through one-on one tutoring, mentorship, and enrichment activities , is facing difficulty in managing consistent communication with parents and volunteers. Each of these audiences requires different channels and information, and currently, sending paper to the home through students has become the primary channel for communicating with parents. The reliability of this practice is limited but continues because parents’ contact information, such as phone number or email, changes frequently.

Rationale: Since CHAT is facing …

Tatami: An Open Source Enterprise Social Network, Kenny Hegeland, Jeremy Narron, Kameron Spruill

Capstone Design Expo Posters

Tatami is an open source enterprise social network created by Ippon, a consulting and software design company with offices in France and the USA. Any company can install Tatami, allowing its employees to communicate in a Twitter-like fashion. Self-hosting Tatami also lets a company retain ownership of its data, keeping it out of the hands of third parties.

Tatami’s front end was originally coded using the Backbone.js library, which can make it challenging to add and modify features. Ippon decided to have it rewritten using the AngularJS web application framework, which will fix the previously mentioned problems. This rewrite will …

The Optimization And Comparison Of A Cerium Salt-Based Phosphate Filtration System To Industry Standard Phosphate Removal Water Filtration Systems, Nicholas Seymour, Snehi Shrestha, Laura Viktoria Pretzman

Capstone Design Expo Posters

Phosphorous, being one of the fundamental building blocks of life, has been linked with the increase of cyanobacteria and algae growth. One of the main ways that phosphorous enters the marine ecosystem is through the form of runoff phosphates from fertilizers and industrial processes. In addition to disrupting the biology of ecosystems another drawback of excess of phosphates is the tendency for these chemical groups to form scale buildup on metal through the form of calcium phosphate.

The goal of our project is to investigate a novel way of removing phosphate groups from wastewater with the use of the rare …

Rapid Diagnostics With Nanoparticles, Lance Johnson, Sai Katikala, Maaz Nawaz

Capstone Design Expo Posters

More than 500,000 open-heart surgeries are performed in the United States every year. The anticoagulant Heparin is used to decrease the likelihood of thrombosis or hemorrhaging in each surgery by bonding to the enzyme inhibitor antithrombin III (AT-III). However, anesthesiologists currently lack the ability to measure antithrombin levels in a patient quickly, making appropriate Heparin dosages difficult to determine and possibly resulting in thrombosis or hemorrhaging if thrombin levels move outside the allowable range. This could be prevented with a simple bedside test. Current tests use gold, but we believe Iron (III) Oxide (commonly known as rust) can be used …

A Treatment For Menorrhagia And Irregular Menstruation: Free Flowing Cryo-Fluid Endometrial Ablation, Julia Biddle, Hubertina Rose Tolpa, Krystal Zentgraf

Capstone Design Expo Posters

Menorrhagia (abnormally heavy and prolonged menstrual period) is a condition suffered by many women; these women have menstrual flow greater than 80 mL per cycle compared to the average 30 mL for normal cycles. The area of the uterus responsible for menorrhagia is the regenerative basal layer of the endometrium (inner uterine layer). In order to relieve menorrhagia, the endometrium needs to be destroyed through the basal layer. This project looks to address issues which patients face with current standard menorrhagia treatments, such as invasiveness, intense pain, or incomplete treatment of the uterine wall, by developing a superior remedy.

The …

Separation Technologies Of Base Oils: The Optimization Of An Anaerobic Thermal Desorption Unit, Kelsey Mangham, Nicholas Montesdeoca, Michael "Ngyuon" Lay

Capstone Design Expo Posters

There has been a recent increase in the amount of oil and natural gas exploration due to fuel reserves that were once inaccessible in North America becoming available through methods such as hydraulic fracturing and horizontal drilling. However, these methods of exploration generate substantial amounts of oil contaminated waste which pose significant pollution risks of which current methods of treatment are slow and ineffective. This project aims to design a better operating process for use with Anaerobic Thermal Desorption Units (ATDU) that are currently manufactured by RLC Technologies which offer more environmentally safe and quick processing of such wastes.

Current …

A Device For The Objective Assessment Of Adhd Using Eye Movements, Ankita Dosaj, Jefferson Overlin, Cassie Turnage

Capstone Design Expo Posters

Attention deficit hyperactivity disorder (ADHD) is a commonly diagnosed psychiatric disorder characterized by lack of focus, self-control,and hyperactivity. ADHD is difficult to diagnose without extensive observation by an expert, and even then is often misdiagnosed. Current methods of pediatric diagnosis rely on subjective measures of activity and behavior relative to other children [3]. Proper diagnosis is critical in preventing unnecessary prescription of the powerful, habit-forming nature of the drugs used to manage ADHD, such as Adderall and Ritalin [1][5]. Research has shown that patients with ADHD show abnormalities in reading tests and antisaccade tests, as these tests gauge ability to …

Non-Invasive Blood Glucose Monitoring System, Brittany Martinez, Brittany Noah, David Decker

Capstone Design Expo Posters

The objective of this project is to create a non-invasive hypoglycemic alert system that will detect a drop in blood sugar in type 1 diabetics during sleep. This will be achieved by creating an algorithm that couples heart rate variability with skin conductance to increase the accuracy of hypoglycemia detection. The device will be housed in a torso strap that will include: electrodes located over the user’s rib cage, a skin conductance sensor placed in the user’s armpit, a microcontroller to collect and process the data, and vibrating motors that will awaken the patient if hypoglycemia is detected. Integrating the …

A Non-Contact System For Measuring Wrist And Carpal Kinematics, Shruthi Muralidharan, Kristina Hendel, Joseph Newton, Vivek Patel

Capstone Design Expo Posters

Ligamentous and bone injuries in the wrist affect tens of thousands of adults per year and leads to abnormal function. Surgical procedures as well as physical therapy intended to restorefunction have room for improvement. Measuring wrist kinematics of the small carpal bones is necessary to understand the effect of ligamentous injury during normal motion.Currently there are motion analysis systems that are used to track large scale movementfor total body kinematics such as gait analysis. The accuracy of these systems is catered toward capturing gross movement and cannot precisely measure on the order of millimeters necessary for carpal kinematics. There are …

Improved Lower-Arm Prosthesis, Trent Ernst, Eric Henderson, Patrick Borges, Taylor Powell

Capstone Design Expo Posters

Over the past few decades, innovations in myoelectric sensing in upper limb prostheses have given systems the ability to read, detect, and emulate fine motor control in an increasingly realistic manner. However, the practical impact that these scientific accomplishments yield is significantly limited by the lack of adoption witnessed by patients who are given such prosthetics. Some people see the device as a burden rather than an improvement. To address this issue, we propose the development of an improved lower arm prosthesis. This prosthesis is intended to encourage patient adoption and retention by emphasizing simplicity and comfort over technical precision. …

Inertial Electrostatic Confinement Fusor, Cody Boyd, Brian Hortelano, Yonathan Kassaye, Dimitris Killinger, Adam Stanfield, Jordan Stark, Thomas Veilleux, Nick Reuter

Capstone Design Expo Posters

The VCU Inertial Electrostatic Confinement (IEC) Fusor design project is a multi-year and multi-disciplinary venture. It was started as a means to build a neutron generator for the Mechanical and Nuclear Engineering department at VCU. The IEC fusor is a device based on the designs of Philo T. Farnsworth, inventor of the cathode ray tube. Our design utilizes a high voltage cathode located in a vacuum chamber that is filled with deuterium gas. This high voltage accelerates the deuterium particles towards the center of the chamber, resulting in deuterium-deuterium (D-D) fusion. This reaction creates a bright purple glow that can …