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2015

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Articles 4141 - 4170 of 7527

Full-Text Articles in Engineering

Wireless Chemical Sensing Schemes Using Environmentally Sensitive Hydrogels, Jun Hyeong Park Apr 2015

Wireless Chemical Sensing Schemes Using Environmentally Sensitive Hydrogels, Jun Hyeong Park

Open Access Dissertations

In situ sensing of chemical parameters such as pH, glucose, enzymes, and other analytes is of immense importance in health care and environmental monitoring. There has been considerable research in this area using hydrogels as a chemo-mechanical transducer. Hydrogels are water-swollen polymers containing chemical groups that are sensitive to environmental stimuli. When there is a chemical change, e.g. alkali to acidic pH, hydrogel swells or shrinks. This reversible volume change can be coupled to capacitive, inductive or other sensing mechanisms. Despite many years of research, hydrogel-based sensors have not been of practical utility. This has been due to several reasons …

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Distributed Real-Time Hybrid Simulation: Modeling, Development And Experimental Validation, Ali Irmak Ozdagli Apr 2015

Distributed Real-Time Hybrid Simulation: Modeling, Development And Experimental Validation, Ali Irmak Ozdagli

Open Access Dissertations

Real-time hybrid simulation (RTHS) has become a recognized methodology for isolating and evaluating performance of critical structural components under potentially catastrophic events such as earthquakes. Although RTHS is efficient in its utilization of equipment and space compared to traditional testing methods such as shake table testing, laboratory resources may not always be available in one location to conduct appropriate large-scale experiments. Consequently, distributed systems, capable of connecting multiple RTHS setups located at numerous geographically distributed facilities through information exchange, become essential. This dissertation focuses on the development, evaluation and validation of a new distributed RTHS (dRTHS) platform enabling integration of …

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Optimizing The Neural Response To Electrical Stimulation And Exploring New Applications Of Neurostimulation, Kurt Yuqin Qing Apr 2015

Optimizing The Neural Response To Electrical Stimulation And Exploring New Applications Of Neurostimulation, Kurt Yuqin Qing

Open Access Dissertations

Electrical stimulation has been successful in treating patients who suffer from neurologic and neuropsychiatric disorders that are resistant to standard treatments. For deep brain stimulation (DBS), its official approved use has been limited to mainly motor disorders, such as Parkinson's disease and essential tremor. Alcohol use disorder, and addictive disorders in general, is a prevalent condition that is difficult to treat long-term. To determine whether DBS can reduce alcohol drinking in animals, voluntary alcohol consumption of alcohol-preferring rats before, during, and after stimulation of the nucleus accumbens shell were compared. Intake levels in the low stimulus intensity group (n=3, 100&mgr;A …

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The Role Of Death-Associated Protein Kinase In Endothelial Apoptosis Under Fluid Shear Stress, Keith R. Rennier Apr 2015

The Role Of Death-Associated Protein Kinase In Endothelial Apoptosis Under Fluid Shear Stress, Keith R. Rennier

Open Access Dissertations

Endothelial cells are the interface between hemodynamic fluid flow and vascular tissue contact. They actively translate physical and chemical stimuli into intracellular signaling cascades which in turn regulate cell function, and endothelial dysfunction leads to inflammation and diseased conditions. For example, atherosclerosis, a chronic vascular disease, favorably develops in regions of disturbed fluid flow and low shear stress. Apoptosis, or programmed cell death, must be properly regulated to maintain homeostasis in the vascular wall. The loss of apoptosis control, as seen in low shear stress regions, is implicated in various diseases such as atherosclerosis and cancer. Death-associated protein kinase, DAPK …

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Sintering Techniques For Microstructure Control In Ceramics, Andrew T. Rosenberger Apr 2015

Sintering Techniques For Microstructure Control In Ceramics, Andrew T. Rosenberger

Open Access Dissertations

Sintering techniques can be manipulated to enhance densification in difficult to sinter materials and to produce property enhancing microstructures. However, the interplay between materials, sintering techniques, and end properties is not fully understood in many material systems, and some fundamental aspects of sintering such as the nature of the effects of electric fields remains unknown. The processing property relationships were examined in two classes of materials; zirconium diboride ultra high temperature ceramic composites, and all solid lithium-ion battery phosphate materials. ^ Investigation of zirconium diboride ceramics focused on the effects of zirconium carbide as a secondary or tertiary phase in …

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Automated Segmentation, Detection And Fitting Of Piping Elements From Terrestrial Lidar Data, Yun-Ting Su Apr 2015

Automated Segmentation, Detection And Fitting Of Piping Elements From Terrestrial Lidar Data, Yun-Ting Su

Open Access Dissertations

Since the invention of light detection and ranging (LIDAR) in the early 1960s, it has been adopted for use in numerous applications, from topographical mapping with airborne LIDAR platforms to surveying of urban sites with terrestrial LIDAR systems. Static terrestrial LIDAR has become an especially effective tool for surveying, in some cases replacing traditional techniques such as electronic total stations and GPS methods. Current state-of-the-art LIDAR scanners have very fine spatial resolution, generating precise 3D point cloud data with millimeter accuracy. Therefore, LIDAR data can provide 3D details of a scene with an unprecedented level of details. However, automated exploitation …

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Understanding How Adults Approach Technological Challenges: A Sequential Mixed Methods Research, Mariana Tafur Arciniegas Apr 2015

Understanding How Adults Approach Technological Challenges: A Sequential Mixed Methods Research, Mariana Tafur Arciniegas

Open Access Dissertations

People from all backgrounds engage with technology in their everyday lives. There is, however, a gap in the public's understanding of technology and limited research on how engineers and non-engineers approach technological challenges. Prior studies have focused on the public's understanding of technology but limited research has been conducted on how people deal with technological challenges as part of their everyday lives. Studying how individuals with non-STEM backgrounds engage with technology will contribute a more comprehensive understanding of strategies for closing the technological literacy gap. Taking into account that technology developments rapidly occur, lifelong learning skills are another critical dimension …

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The Pathological Role Of Acrolein In Experimental Autoimmune Encephalomyelitis And Multiple Sclerosis, Melissa A. Tully Apr 2015

The Pathological Role Of Acrolein In Experimental Autoimmune Encephalomyelitis And Multiple Sclerosis, Melissa A. Tully

Open Access Dissertations

Multiple sclerosis (MS) is an autoimmune demyelinating neuropathy that affects nearly 2.5 million people worldwide. Despite substantial efforts, few treatments are currently available largely due to limited knowledge of pathogenic mechanisms underlying the disease. The immune-inflammatory nature of the pathology has prompted investigation of the role of oxidative stress in disease development and progression; however targeting reactive oxygen species for neutralization has had marginal success therapeutically, suggesting that an alternate oxidative stress-related target would prove beneficial. Recently, our lab has implicated acrolein, a highly reactive aldehyde that is both a byproduct and catalyst of lipid peroxidation, as a potential therapeutic …

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Well-Posedness And Convergence Of Cfd Two-Fluid Model For Bubbly Flows, Avinash Vaidheeswaran Apr 2015

Well-Posedness And Convergence Of Cfd Two-Fluid Model For Bubbly Flows, Avinash Vaidheeswaran

Open Access Dissertations

The current research is focused on developing a well-posed multidimensional CFD two-fluid model (TFM) for bubbly flows. Two-phase flows exhibit a wide range of local flow instabilities such as Kelvin-Helmholtz, Rayleigh-Taylor, plume and jet instabilities. They arise due to the density difference and/or the relative velocity between the two phases. A physically correct TFM is essential to model these instabilities. However, this is not the case with the TFMs in numerical codes, which can be shown to have complex eigenvalues due to incompleteness and hence are ill-posed as initial value problems. A common approach to regularize an incomplete TFM is …

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System Importance Measures: A New Approach To Resilient Systems-Of-Systems, Payuna Uday Apr 2015

System Importance Measures: A New Approach To Resilient Systems-Of-Systems, Payuna Uday

Open Access Dissertations

Resilience is the ability to withstand and recover rapidly from disruptions. While this attribute has been the focus of research in several fields, in the case of system-of-systems (SoSs), addressing resilience is particularly interesting and challenging. As infrastructure SoSs, such as power, transportation, and communication networks, grow in complexity and interconnectivity, measuring and improving the resilience of these SoSs is vital in terms of safety and providing uninterrupted services. ^ The characteristics of systems-of-systems make analysis and design of resilience challenging. However, these features also offer opportunities to make SoSs resilient using unconventional methods. In this research, we present a …

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Improving Capacity-Performance Tradeoffs In The Storage Tier, Eric P. Villasenor Apr 2015

Improving Capacity-Performance Tradeoffs In The Storage Tier, Eric P. Villasenor

Open Access Dissertations

Data-set sizes are growing. New techniques are emerging to organize and analyze these data-sets. There is a key access pattern emerging with these new techniques, large sequential file accesses. The trend toward bigger files exists to help amortize the cost of data accesses from the storage layer, as many workloads are recognized to be I/O bound. The storage layer is widely recognized as the slowest layer in the system. This work focuses on the tradeoff one can make with that storage capacity to improve system performance. ^ Capacity can be leveraged for improved availability or improved performance. This tradeoff is …

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Surface Modification Of Traditional And Bioresorbable Metallic Implant Materials For Improved Biocompatibility, Emily Kristine Walker Apr 2015

Surface Modification Of Traditional And Bioresorbable Metallic Implant Materials For Improved Biocompatibility, Emily Kristine Walker

Open Access Dissertations

Due to their strength, elasticity, and durability, a variety of metal alloys are commonly used in medical implants. Traditionally, corrosion-resistant metals have been preferred. These permanent materials can cause negative systemic and local tissue effects in the long-term. Permanent stenting can lead to late-stent thrombosis and in-stent restenosis. Metallic pins and screws for fracture fixation can corrode and fail, cause loss of bone mass, and contribute to inflammation and pain at the implant site, requiring reintervention. Corrodible metallic implants have the potential to prevent many of these complications by providing transient support to the affected tissue, dissolving at a rate …

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Assessment Of High-Fidelity Collision Models In The Direct Simulation Monte Carlo Method, Andrew Brian Weaver Apr 2015

Assessment Of High-Fidelity Collision Models In The Direct Simulation Monte Carlo Method, Andrew Brian Weaver

Open Access Dissertations

Advances in computer technology over the decades has allowed for more complex physics to be modeled in the DSMC method. Beginning with the first paper on DSMC in 1963, 30,000 collision events per hour were simulated using a simple hard sphere model. Today, more than 10 billion collision events can be simulated per hour for the same problem. Many new and more physically realistic collision models such as the Lennard-Jones potential and the forced harmonic oscillator model have been introduced into DSMC. However, the fact that computer resources are more readily available and higher-fidelity models have been developed does not …

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Growth Of Low Disorder Gaas/Algaas Heterostructures By Molecular Beam Epitaxy For The Study Of Correlated Electron Phases In Two Dimensions, John D. Watson Apr 2015

Growth Of Low Disorder Gaas/Algaas Heterostructures By Molecular Beam Epitaxy For The Study Of Correlated Electron Phases In Two Dimensions, John D. Watson

Open Access Dissertations

The unparalleled quality of GaAs/AlGaAs heterostructures grown by molecular beam epitaxy has enabled a wide range of experiments probing interaction effects in two-dimensional electron and hole gases. This dissertation presents work aimed at further understanding the key material-related issues currently limiting the quality of these 2D systems, particularly in relation to the fractional quantum Hall effect in the 2nd Landau level and spin-based implementations of quantum computation.^ The manuscript begins with a theoretical introduction to the quantum Hall effect which outlines the experimental conditions necessary to study the physics of interest and motivates the use of the semiconductor growth …

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Encapsulation Of Chemical Catalyst And Structural Epoxy In Microcapsules Generated Via Microcapillary Devices, Congwang Ye Apr 2015

Encapsulation Of Chemical Catalyst And Structural Epoxy In Microcapsules Generated Via Microcapillary Devices, Congwang Ye

Open Access Dissertations

Protection and controlled release of chemicals through encapsulation have been extensively used in daily applications such as drug delivery, food processing, enzyme stabilization, and chemical storage. A significant need for further development in this area is to reduce the capsule size and to obtain more predictable performance by narrowing the capsule geometry distribution. For the past decade, microfluidics have been rapidly developed to become a popular technique for the generation of monodisperse single/double/multiple emulsion drops in the micrometer to millimeter size range. With this technique, polymeric microcapsules with a narrow size distribution can be fabricated by adding different polymer blends …

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A Three Constituent Mixture Theory Model Of Cutaneous And Subcutaneous Tissue In The Context Of Neonatal Pressure Ulcer Etiology And Prevention, Anne Dye Zakrajsek Apr 2015

A Three Constituent Mixture Theory Model Of Cutaneous And Subcutaneous Tissue In The Context Of Neonatal Pressure Ulcer Etiology And Prevention, Anne Dye Zakrajsek

Open Access Dissertations

Localized ischemia, impaired interstitial fluid flow, and sustained mechanical loading of cells have all been hypothesized as mechanisms of pressure ulcer (PrU) etiology. Time-varying loading has experimentally been shown to increase fluid flow in human skin in vivo. Towards the design of prophylactic protocols and treatment modalities for PrU management there is a need for an analytical model to investigate the local fluid flow characteristics of skin tissue under time-varying loading. In this study, a triphasic mixture theory model with constituents of extracellular matrix, interstitial fluid, and blood was calibrated and validated and used to investigate stress and fluid velocity …

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Effect Of Maleic Acid On The Selectivity Of Glucose And Fructose Dehydration And Degradation, Ximing Zhang Apr 2015

Effect Of Maleic Acid On The Selectivity Of Glucose And Fructose Dehydration And Degradation, Ximing Zhang

Open Access Dissertations

5-Hydroxymethyfurfural (HMF), a platform chemical can upgrade to a variety of fuels and polymers, can be manufactured from lignocellulose. This study focuses on the Lewis and Brønsted acid effect on hexose dehydration for HMF production. We report the positive effect of maleic acid, a dicarboxylic acid used as Brønsted acid, on the selectivity of hexose dehydration to 5-hydroxymethyfurfural (HMF), and subsequent hydrolysis to levulinic and formic acids. We also describe the kinetic analysis of a Lewis acid (AlCl 3) alone and in combination with HCl or maleic acid to catalyze the isomerization of glucose to fructose, dehydration of fructose …

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Semcache: Semantics-Aware Caching For Efficient Gpu Offloading, Nabeel Al-Saber Apr 2015

Semcache: Semantics-Aware Caching For Efficient Gpu Offloading, Nabeel Al-Saber

Open Access Dissertations

Graphical Processing Units (GPUs) offer massive, highly-efficient parallelism, making them an attractive target for computation-intensive applications. However, GPUs have a separate memory space which introduces the complexity of manually handling explicit data movements between GPU and CPU memory spaces. Although GPU kernels/libraries have made it easy to improve application performance by offloading computation to GPUs, unfortunately it is very difficult to manually optimize CPU-GPU communication between multiple kernel invocations to avoid redundant communication when using these kernels with complex applications. ^ In this thesis, we introduce SemCache, a semantics-aware GPU cache that automatically manages CPU-GPU communication in addition to optimizing …

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Photochemistry Of Single-Walled Carbon Nanotubes In The Aquatic Environment, And Their Extraction From Soils, Somayeh Beigzadehmilani Apr 2015

Photochemistry Of Single-Walled Carbon Nanotubes In The Aquatic Environment, And Their Extraction From Soils, Somayeh Beigzadehmilani

Open Access Dissertations

Carbon nanotubes (CNTs) are a class of engineered nanoparticles, composed of an array of sp2 carbon atoms arranged as fused benzene rings. Due to their exceptional electrical, mechanical, and physical properties, CNTs find applications in construction, aerospace, and medical industries. In the United States, CNTs already had an annual production of 2,000 tons in 2011. This rate of annual production indicates that CNTs will find their way into the environment, which will result in certain environmental exposure. Yet, there have not been sufficient and definitive studies on the health and environment effects of CNTs. For example, additional information regarding environmental …

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Modular Approach To Spintronics, Kerem Yunus Camsari Apr 2015

Modular Approach To Spintronics, Kerem Yunus Camsari

Open Access Dissertations

There has been enormous progress in the last two decades, effectively combining spintronics and magnetics into a powerful force that is shaping the field of memory devices. New materials and phenomena continue to be discovered at an impressive rate, providing an ever-increasing set of building blocks that could be exploited in designing transistor-like functional devices of the future. The objective of this thesis is to provide a quantitative foundation for this building block approach, so that new discoveries can be integrated into functional device concepts, quickly analyzed and critically evaluated. Through careful benchmarking against available theory and experiments we establish …

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Behavior And Design Of Steel-Plate Composite (Sc) Walls For Blast Loads, Jakob C Bruhl Apr 2015

Behavior And Design Of Steel-Plate Composite (Sc) Walls For Blast Loads, Jakob C Bruhl

Open Access Dissertations

Reinforced concrete (RC) structures have historically been the preferred choice for blast resistant structures because of their mass and the ductility provided by steel reinforcement. Steel-plate composite (SC) walls are a viable alternative to RC for protecting the infrastructure against explosive threats. SC structures consist of two steel faceplates with plain concrete core between them. The steel faceplates are anchored to the concrete using stud anchors and connected to each other using tie bars. SC structures provide mass from the concrete infill and ductility from the continuous external steel faceplates. This dissertation presents findings and recommendations from experimental and analytical …

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Circular Bessel Field Statistics And The Pursuit Of Far-Subwavelength Resolution, Yulu Chen Apr 2015

Circular Bessel Field Statistics And The Pursuit Of Far-Subwavelength Resolution, Yulu Chen

Open Access Dissertations

The statistical description of wave propagation in random media is important for many applications. While polarized light in systems with weakly interacting scatterers and sufficient overall scatter has zero-mean circular Gaussian statistics, the underlying assumptions break down in the Anderson localization and weakly scattering regimes. Although probability density functions for wave intensity and amplitude exist beyond Gaussian statistics, suitable statistical descriptions for the field with strong and weak random scatter were unknown. The first analytical probability density function for the field that is effective in both the Anderson localization regime and the weakly scattering regime is derived by modeling the …

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Experimental And Modeling Investigation Of Cellulose Nanocrystals Polymer Composite Fibers, Si Chen Apr 2015

Experimental And Modeling Investigation Of Cellulose Nanocrystals Polymer Composite Fibers, Si Chen

Open Access Dissertations

Cellulose nanocrystals (CNCs) are a class of newly developed and sustainable nanomaterial derived from cellulose-based materials such as wood. There have been substantial research efforts to utilize these materials as reinforcing agents. However, in order to develop CNC nanocomposites with industrial applications, it is necessary to understand how addition of CNCs affect the properties of the polymer nanocomposite. In the present work, several approaches, experimental and theoretical, are presented in an effort to characterize and understand the effect of CNCs on the properties of polymer CNC fibers. ^ Two experimental methods were used to develop cellulose acetate (CA) and CNC …

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Near-Inertial Internal Poincare Waves In Lake Michigan: Seasonal Variability And Effects On Lateral Dispersion And Turbulent Mixing, Jun M Choi Apr 2015

Near-Inertial Internal Poincare Waves In Lake Michigan: Seasonal Variability And Effects On Lateral Dispersion And Turbulent Mixing, Jun M Choi

Open Access Dissertations

A dominant physical process in stratified Lake Michigan is near-inertial internal Poincaré waves. The near-inertial internal Poincaré waves is described as locally quasi-uniform currents in the lateral direction, with vertically-sheared structures rotating clockwise at a near-inertial period. The goal of this dissertation is to investigate their seasonal variation and the potential roles on lateral dispersion and vertical mixing. ^ At this mid-lake location, the Poincaré wave is seen to describe more than 80% of the observed surface current variability for much of the year, with characteristic near-inertial frequency and clockwise-rotating velocities. The wave persists during the stratified period, and is …

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Modeling Person-To-Person Contaminant Transport In Enclosed Environments, Chun Chen Apr 2015

Modeling Person-To-Person Contaminant Transport In Enclosed Environments, Chun Chen

Open Access Dissertations

It is essential to predict person-to-person contaminant transport in enclosed environments to improve air distribution design and reduce the infection risk from airborne infectious diseases. This study aims to improve and accelerate the simulation of person-to-person contaminant transport in enclosed environments. ^ This investigation first conducted experimental measurements of person-to-person contaminant transport in an office mockup and the first-class cabin of a functional MD-82 aircraft. The experimental data of steady-state airflow, temperature, and gas contaminant concentration fields obtained in the office were used to validate the steady-state computational fluid dynamics (CFD) models. In the aircraft cabin, the transient particle concentrations …

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Difficulty As A Concept Inventory Design Consideration: An Exploratory Study Of The Concept Assessment Tool For Statics (Cats), Dana L. Denick Apr 2015

Difficulty As A Concept Inventory Design Consideration: An Exploratory Study Of The Concept Assessment Tool For Statics (Cats), Dana L. Denick

Open Access Dissertations

The ability for engineering students to apply mathematic, scientific and engineering knowledge to real-life problems depends greatly on developing deep conceptual knowledge that structures and relates the meaning of underlying principles. Concept inventories have emerged as a class of tests typically developed for use in higher education science and engineering courses. Concept Inventories (CIs) are multiple-choice tests that are designed to assess students' conceptual understanding within a specific content domain. For example, the CI explored within this study, the Concept Assessment Tool for Statics (CATS) is intended to measure students' understanding of the concepts underlying the domain of engineering statics. …

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Tunable Organization Of Cellulose Nanocrystals For Controlled Thermal And Optical Response, Jairo A. Diaz Amaya Apr 2015

Tunable Organization Of Cellulose Nanocrystals For Controlled Thermal And Optical Response, Jairo A. Diaz Amaya

Open Access Dissertations

The biorenewable nature of cellulose nanocrystals (CNCs) has opened up new opportunities for cost-effective, sustainable materials design. By taking advantage of their distinctive structural properties and self-assembly, promising applications have started to nurture the fields of flexible electronics, biomaterials, and nanocomposites. CNCs exhibit two fundamental characteristics: rod-like morphology (5-20 nm wide, 50-500 nm long), and lyotropic behavior (i.e., liquid crystalline mesophases formed in solvents), which offer unique opportunities for structural control and fine tuning of thermal and optical properties based on a proper understanding of their individual behavior and interactions at different length scales. In the present work, we attempt …

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Unveiling The Mechanical Behavior Of The Rod-Like Microstructure In The Radular Teeth Of Cryptochiton Stelleri, Enrique Escobar De Obaldia Apr 2015

Unveiling The Mechanical Behavior Of The Rod-Like Microstructure In The Radular Teeth Of Cryptochiton Stelleri, Enrique Escobar De Obaldia

Open Access Dissertations

Natural ceramics provided with high volume fractions of mineralized materials that are surrounded by a weak organic interface combine the stiff mechanical behavior of building blocks, like hydroxyapatite or aragonite, and the compliance of the organic surroundings. Unique mechanical properties (e.g. light density and toughness) distinguish bio-composites from common engineering materials. A key example is the highly mineralized shell of the radular teeth of the Crypochiton stelleri. Nature has provided the radular teeth with a highly oriented rod-like microstructure of nano-scale dimensions embedded in a matrix of chitin sheaths. Compared to other biological materials, the external iron oxide layer of …

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International Water And Food Security Development: Performance Evaluation And Assessment Of Research Needs At Multiple Scales, Caitlin Anne Grady Apr 2015

International Water And Food Security Development: Performance Evaluation And Assessment Of Research Needs At Multiple Scales, Caitlin Anne Grady

Open Access Dissertations

Water and food security remain the top development challenges of the decade, and perhaps the century. Since the Millennium Development Goals were established in 2000, billions of people have obtained access to more food, better nutrition, improved water, and basic sanitation facilities worldwide. This progress has been accomplished through the dedication of international organizations, non-governmental organizations, country-level governments, private corporations, and individuals at international, regional, and local scales. Truly tremendous strides have been made in water and food provisioning for humans worldwide. These past two decades have also seen the largest population growth on record, the highest rates of childhood …

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Control Of Modular Multilevel Converters For Grid Integration Of Full-Scale Wind Energy Conversion Systems, Suman Debnath Apr 2015

Control Of Modular Multilevel Converters For Grid Integration Of Full-Scale Wind Energy Conversion Systems, Suman Debnath

Open Access Dissertations

The growing demand for wind power generation has pushed the capacity of wind turbines towards MW power levels. Higher capacity of the wind turbines necessitates operation of the generators and power electronic conversion systems at higher voltage/power levels. The power electronic conversion system of a wind energy conversion system (WECS) needs to meet the stringent requirements in terms of reliability, efficiency, scalability and ease of maintenance, power quality, and dv/dt stress on the generator/transformer. Although the multilevel converters including the neutral point clamped (NPC) converter and the active NPC converter meet most of the requirements, they fall short in reliability …

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