Engineering Commons^™

Assessing Corrosion Damage In Post -Tensioned Concrete Structures Using Acoustic Emission & A Preliminary Investigation Of Biopolymer Doped Cement Mortar For Use In Structural Restoration, Aditya Appalla

Theses and Dissertations

A sizeable portion of the civil infrastructure is made from concrete. An estimate shows that about 7 billion cubic meters of concrete is made annually worldwide. With the deterioration of the infrastructure due to aging or external factors, significant monetary and technological investment is needed for condition evaluation, maintenance and repair. Two areas that account for a considerable portion of this investment are condition evaluation for maintenance of corroded concrete structures and mortar patching for repair and rehabilitation.

The primary method of evaluation of a structure is by visual inspection. But this method is limited as some crucial areas in …

Iii-V Nitride Micro- And Nano-Scale Cantilevers For Multimodal Sensing Applications, Ehtesham Bin Quddus

Theses and Dissertations

Recent research trends in chemical and biological sensing have been geared toward developing molecular sensor devices that are fast, label free, miniaturized and portable. The performance of these devices can be dramatically improved by utilizing multimodal detection techniques, new materials and micro-/nanofabrication technologies. This is especially true for micro-/nanoscale cantilever sensors, which undergo changes in mechanical or electrical properties upon the specific binding of molecules. To develop the sensor devices with the above attributes, we utilized III-V nitride materials: InN nanowires for realizing nanoscale cantilevers and AlGaN/GaN heterostuctures with or without embedded HFETs, for developing microcantilevers. There are mainly two …

Wireless Pressure Sensor System For Medical Applications, Xuehe Wang

Theses and Dissertations

Telemedicine in the modern era is a rapidly developing industry. In a telemedicine system, sensor is the key elements and play important role in any telemedicine applications, especially implantable sensors. Unlike traditional in vitro sensors, there are some special requirements for them like battery-less, compact, and bio-friendly. Therefore, many researchers in institutes as well as in industry are continually developing implantable sensor and sensor system to fulfill the requirements of medical applications.Nine in one thousand people in the United States are born with congenital heart defects and sixty percent die before one year old. As a result, it will be …

Numerical Study Of Stable Tearing Crack Growth Events Using The Cohesive Zone Model Approach, Xin Chen

Theses and Dissertations

Numerical analysis of stable tearing crack growth events plays an important role in assessing the structural integrity and residual strength of critical engineering structures. The cohesive zone model (CZM) has been widely applied to simulate fracture processes in a variety of material systems. However, its application to the study of elastic-plastic stable tearing crack growth events in ductile materials, especially under mixed-mode loading conditions, has been limited. The current study is aimed at investigating the applicability of the CZM based approach in simulating mixed-mode stable tearing crack growth events in aluminum alloys. In the simulations, which are carried out using …

Automated Detection Of Incomplete Exhalation As An Indirect Detection Of Auto-Peep On Mechanically Ventilated Adults, Nyimas Arief

Theses and Dissertations

Auto-PEEP is auto positive end-expiratory pressure due to excessive amounts of alveolar gas produced by sustained recurrent incomplete exhalation. Incomplete exhalation occurs when the exhaled breath never reaches a flow rate of 0 L/min. The objective of this dissertation is to develop an automated detection system of auto-PEEP through incomplete exhalation as revealed by ventilator graphics for mechanically ventilated adults. Auto-PEEP can cause adverse effects if allowed to linger and if not quickly identified. An automated detection system will be instrumental in helping to quickly identify auto-PEEP. A computerized algorithm was developed to detect incomplete exhalation based on the following …

Mechanical Characterization Of Composite Repairs For Fiber-Glass Wind Turbine Blades, Tanveer Singh Chawla

Theses and Dissertations

While in service, wind turbine blades experience various modes of loading. An example is impact loading in the form of hail or bird strikes, which might lead to localized damage or formation of cracks a few plies deep on the blade surface. One of the methods to conduct repairs on wind turbine blades that are damaged while in service is hand lay-up of the repair part after grinding out the damaged portion and some of its surrounding area. The resin used for such repairs usually differs from the parent plate resin in composition and properties such as gel time, viscosity, …

Osteon-Mimetic Nanocomposite Materials For Bone Regeneration, Ozan Karaman

Theses and Dissertations

The limitations of large bone defect regeneration has brought the focus of Bone Tissue Engineering research on fabricating three-dimensional bone-mimetic grafts that could enhance osteogenesis and vascularization. Osteons composed of apatite-deposited aligned collagen nanofiber layers are the fundamental building blocks of cortical bone. In natural cortical bone, mineralization is mediated by extracellular matrix (ECM) proteins with amino acid sequences rich in glutamic acid. This dissertation is focused on the establishment of a novel biomimetic approach to engineer scaffolds for healing large bone defects.

In the first part, we investigated the effect of calcium phosphate (CaP) deposition on aligned surface-modified nanofibers …

Effect Of Physiological Oxygen Levels On Osteogenic Differentiation Of Adipose-Derived Stem Cells, Suchit Sahai

Theses and Dissertations

Regenerative medicine presents exciting strategies for healing critical-size bone defects through the implantation of cells and biocompatible scaffolds. Most in vitro studies are performed in atmospheric oxygen conditions (~20%), which do not accurately mimic the CSD microenvironment. Due to damage to the vasculature at CSDs, oxygen levels fall into the hypoxic range (<5%), which can impact viability, proliferation and differentiation of the cells employed for bone regeneration. Understanding the cellular responses to hypoxia has grown primarily from study of individual molecular factors. The master regulator of adaptive responses to low oxygen availability is the nuclear factor, hypoxia-inducible factor-1. HIF-1 is a heterodimeric protein, stable below 6% O2 condition in the nucleus and has been shown to play a role in angiogenic-osteogenic coupling. We have developed a responsive, fluorescent, hypoxia detection system and determined whether HIF activity can be tracked in both 2-D and 3-D cultures. Adipose-derived stem cells (ASCs) were selected due to their broad utilization in tissue engineering strategies and characterized the influence of HIF signaling on its phenotype. The work done identified that of hypoxia impaired osteogenic differentiation of ASCs in both 2-D and 3-D cultures and HIF-1 did not mediate this effect. Ischemic preconditioning (IPC) strategy and varied protocols used represents a clinically feasible manipulation of cell preparation to help the survival of implanted ASCs and accelerate osteogenic differentiation at physiological oxygen levels.

Characterizing Hypoxia And Its Behavioral Effects In 3-Dimensional Cell Aggregates, Matthew Lorincz Skiles

Theses and Dissertations

Cell transplantation can be considered a regenerative therapy, an intervention which attempts to replace or restore the function of compromised tissue by harnessing innate properties of cells that cannot be replicated artificially. For such therapies to succeed, it will be necessary to understand and closely match the physiological conditions that govern cell behaviors in vivo. One important factor is low oxygen tension, termed hypoxia, which is often overlooked in vitro. Because oxygen insufficiency can lead to cell death, hypoxia has traditionally been viewed as a negative condition. However, hypoxia can also serve as a potent regulator of crucial cell behaviors …

Investigation Of Three-Way (Twc), Lean Nox Trap (Lnt) And Selective Catalytic Reduction (Scr) Catalysts For Control Of Nox Emissions From Lean-Burn Engines, Christopher Dominic Digiulio

Theses and Dissertations

Lean-burn gasoline engines are approximately 10% more fuel efficient than conventional, stoichiometric-burn ones. Although relatively modest, if implemented across the entire U.S. automotive fleet, this improvement in fuel economy could have far-reaching implications on the amount of gasoline imported in the country on an annual basis. However, the development of a cost-effective catalytic converter catalyst capable of meeting emission regulations for lean-burn vehicles still represents a major technical challenge. Currently, lean NOX trap (LNT) and selective catalytic reduction (SCR) catalysts are used for this purpose, but both systems suffer from significant drawbacks. For example, LNT catalysts generally require high platinum …

Radar Based Navigation In Unknown Terrain, Kyle J. Kauffman

Theses and Dissertations

There is a great need to develop non-GPS based methods for positioning and navigation in situations where GPS is not available. This research focuses on the development of an Ultra-Wideband Orthogonal Frequency Division Multiplexed (UWB-OFDM) radar as a navigation sensor in GPS-denied environments. A side-looking vehicle-fixed UWB-OFDM radar is mounted to a ground or aerial vehicle continuously collecting data. A set of signal processing algorithms and methods are developed which use the raw radar data to aide in calculating the vehicle position and velocity via a simultaneous localization and mapping (SLAM) approach. The radar processing algorithms detect strong, persistent, and …

A Nonparametric Approach To Segmentation Of Ladar Images, Eric A. Buschelman

Theses and Dissertations

The advent of advanced laser radar (ladar) systems that record full-waveform signal data has inspired numerous inquisitions which aspire to extract additional, previously unavailable, information about the illuminated scene from the collected data. The quality of the information, however, is often related to the limitations of the ladar camera used to collect the data. This research project uses full-waveform analysis of ladar signals, and basic principles of optics, to propose a new formulation for an accepted signal model. A new waveform model taking into account backscatter reflectance is the key to overcoming specific deficiencies of the ladar camera at hand, …

Modeling The Effects Of The Local Environment On A Received Gnss Signal, Marshall E. Haker

Theses and Dissertations

There is an ongoing need in the GNSS community for the development of high-fidelity simulators which generate data that replicates what can truly be expected from a challenging environment such as an urban canyon or an indoor environment. The algorithm developed for use in the research in this dissertation, the Signal Decomposition and Parameterization Algorithm (SDPA), is presented in order to respond to this need. This algorithm is designed to decompose a signal received using a GNSS recording and playback system and output parameters that can be used to reconstruct the effects on the signal of the environment local to …

Structural Design Of Flexible Etfe Atrium Enclosures Using A Cable-Spring Support System, Ryan Paul Bessey

Theses and Dissertations

This research designed and analyzed an innovative structural support system for ETFE (ethylene tetrafluoroethylene) atrium roofs between buildings. A cable-spring system was conceived, which is much lighter and more flexible than arches, frames, trusses, and beams which usually support ETFE roofs. Flexibility was a desirable property because the displacements may vary significantly among the buildings supporting the ETFE atrium roof during wind and seismic loading. The springs in the cable-spring system allow large differential displacements without exerting large support reactions on the buildings. The flexibility of the cable-spring system was compared to the cable-strut system which is used to support …

The Effects Of Observations And Maneuvers On Orbit Solutions, Christine M. Schudrowitz

Theses and Dissertations

The purpose of this research is to characterize the performance of the optimal sequential filter used in ODTK with a maneuvering satellite. Specifically, this thesis sought to characterize the performance using two scenarios: performance with a maneuver in between passes and performance with a limited number of measurements. The performance of the filter is evaluated by analyzing the covariance values generated during the orbit estimation process. Larger covariance values signify reduced performance of the filter. Several variables for the maneuvering satellite are used, including the maneuver direction and the maneuver magnitude. The time of the maneuver is also varied, which …

Plantar Measurements To Determine Success Of Surgical Correction Of Stage Iib Adult Acquired Flatfoot Deformity, Erika Matheis

Theses and Dissertations

Adult Acquired Flatfoot Deformity (AAFD) is a progressive disease characterized by mechanical degeneration of the soft tissue structure in the arch of the foot that leads to changes in joint alignment. Surgical intervention commonly via tendon transfer and bony osteotomy is used to restore arch architecture, however there is a lack of quantitative assessments that measure the success of the surgical correction in vivo. Using plantar pressures via Tekscan® HR Mat and surveys (SF-36, FAOS), pre-operative and post-operative measures for six participants were defined, analyzed and compared. A paired t-test showed significant lateral shift for percent body weight during walking …

Complexity Of Bed-Load Transport In Gravel Bed Streams: Data Collection, Prediction, And Analysis, Darren D. Hinton

Theses and Dissertations

Bedload transport has long been known for its complexity. Despite decades of research, significant gaps of understanding exist in the ability to assess and predict bedload movement. This work introduces a comprehensive bedload database that is a compilation of field samples collected over the past 40 years; compares prediction formulae using a subset of the database; evaluates the influence of the armor layer on stream response to sediment input based on a hypothesis linked to one of the tested formulae, presents a mathematically manipulation of the empirical Pagosa Good/Fair formula for bedload transport into a format similar to the semi-empirical …

Information Theoretic Approaches Towards Regulatory Network Inference, Vijender Chaitankar

Theses and Dissertations

In spite of many efforts in the past, inference or reverse engineering of regulatory networks from microarray data remains an unsolved problem in the area of systems biology. Such regulatory networks play a critical role in cellular function and organization and are of interest in the study of a variety of disease areas and ecotoxicology to name a few. This dissertation proposes information theoretic methods/algorithms for inferring regulatory networks from microarray data. Most of the algorithms proposed in this dissertation can be implemented both on time series and multifactorial microarray data sets. The work proposed here infers regulatory networks considering …

Methods For Identifying Acoustic Emissions From The Front Face Of A Small Piezoelectric Blower, Brad K. Solomon

Theses and Dissertations

This thesis focuses on identifying acoustic noise generating components in piezoelectric blowers through transverse velocity measurements and the development of a numerical fluid model. Piezoelectric ceramics have proven useful for many industries and areas of research involving: high precision actuators, noise control, ultrasonic devices, and many other areas. As of late, a unique adaptation of piezoelectric ceramics is surfacing in the area of pumping and cooling. Air pumps that use these ceramics replace the traditional electric motor, resulting in lower power consumption, less moving parts, constant pressure gradients, lower overall weight, and a low profile. The current drawback of this …

Reliability Techniques For Data Communication And Storage In Fpga-Based Circuits, Yubo Li

Theses and Dissertations

This dissertation studies the effects of radiation-induced single-event upsets (SEUs) on field-programmable gate array(FPGA)-based circuits. It analyzes and quantifies a special case in data communication, that is, the synchronization issue of signals when they are sent across clock domains in triple modular redundancy (TMR) circuits with the presence of SEUs. After demonstrating that synchronizing errors cannot be eliminated in such case, this dissertation continues to present novel synchronizer designs that can guarantee reliable synchronization of triplicated signals. Fault injection tests then show that the proposed synchronizers provide between 6 and 10 orders of magnitude longer mean time to failure (MTTF) …

The Effects Of Freestream Turbulence On Serpentine Diffuser Distortion Patterns, Jesse Scott Johnson

Theses and Dissertations

Serpentine diffusers have become a common feature in modern aircraft as they allow for certain benefits that are impossible with a traditional linear configuration. With the benefits, however, come certain disadvantages, namely flow distortions that reduce engine efficiency and decrease engine surge stability margins. These distortions are now being researched comprehensively to determine solutions for mitigating the adverse effects associated with them. This study investigates how varying the freestream turbulence intensity of the flow entering a serpentine diffuser affects the distortion patterns that are produced by the diffuser. Experiments were performed with a model serpentine diffuser on the Annular Cascade …

Liquid-Liquid Equilibrium Of Biodiesel Components, Joseph C. Bell

Theses and Dissertations

Biodiesel is produced from vegetable oils through transesterification. Triglyceride mixtures extracted from oilseed feedstocks are upgraded by reaction with an alcohol in the presence of a catalyst to produce fatty acid esters. This reaction produces a mixture of esters, glycerin, alcohol, and catalyst. Separation of the fatty acid esters (biodiesel) and glycerin can be accomplished through liquid-liquid extraction by water addition. Designing liquid-liquid extraction with water as the solvent requires ternary liquid-liquid equilibrium data for mixtures of water, glycerin, and fatty acid esters. Ternary mixture LLE data have been experimentally measured for several of these systems. Those measured include mixtures …

Best Practices Using Building Information Modeling In Commercial Construction, Simon Beveridge

Theses and Dissertations

There has been an increase in adoption of building information modeling (BIM) by commercial contractors over the past few years but there is not a clear indication of current application or the frequency of each use. This research was undertaken to determine the frequency and best practices of using BIM in commercial construction. Leading commercial contracting firms were contacted and employees were selected to complete a telephone survey that was designed to determine how they are using BIM. It was found that BIM is being used with more frequency on projects, with plans to continue to implement it even further …

Efficient Estimation For Small Multi-Rotor Air Vehicles Operating In Unknown, Indoor Environments, John Charles Macdonald

Theses and Dissertations

In this dissertation we present advances in developing an autonomous air vehicle capable of navigating through unknown, indoor environments. The problem imposes stringent limits on the computational power available onboard the vehicle, but the environment necessitates using 3D sensors such as stereo or RGB-D cameras whose data requires significant processing. We address the problem by proposing and developing key elements of a relative navigation scheme that moves as many processing tasks as possible out of the time-critical functions needed to maintain flight. We present in Chapter 2 analysis and results for an improved multirotor helicopter state estimator. The filter generates …

Investigation Of Possible Novel Peptide Inhibitors To Bag-1 Based On Peptidyl-Biomimetics, Jonathan Brunn

Theses and Dissertations

In this Master’s Thesis Research the results can be summarized from two major tasks: (1) In our first task, we utilized our two protein system (BAG-1 and HSP 70) as part of beta testing of a computational software 1 that can take three dimensional x-ray crystallography information about protein complexes and predict the strength of atom –atom interactions between amino-acid residues Open Contact predicts binding hotspots that can be used to identify short amino acid chains or peptides that mimic that particular binding segment of the larger protein. These peptides are called pepidyl-biomimetics. The peptide can potentially act as an …

Vibrotactile Feedback Generation Using Envelope Waveforms And Eccentric-Mass Motors, Michael G. Plooster

Theses and Dissertations

The usefulness of vibrotactile feedback as a channel to communicate information has been widely recognized. However, most of the recent work on this subject uses actuators that are either too expensive or too large for many practical applications. This thesis explores the generation of vibrotacatile feedback patterns using a simple, inexpensive eccentric-mass motor that is constrained to use a constant voltage and a low on/off switching frequency. In particular, it explores the pulse timing method, which utilizes the slow transient response of the eccentric-mass motor to calculate pulse and rest times for an arbitrary envelope waveform shape. Several hardware tests …

Streamlined Extract Preparation For E. Coli-Based Cell-Free Protein Synthesis And Rapid Site-Specific Incorporation Of Unnatural Amino Acids In Proteins, Prashanta Shrestha

Theses and Dissertations

This thesis reports the viability of E. coli cell extracts prepared using equipment that is both common to biotechnology laboratories and able to process small volume samples and expression of proteins containing unnatural amino acids (UAAs) at higher level using PCR amplified linear DNA templates (LETs) in cell-free protein synthesis (CFPS) system. E. coli-based cell extracts are a vital component of inexpensive and high-yielding CFPS reactions. However, effective preparation of E. coli cell extract is limited to high-pressure homogenizers (French press style or impinge-style) or bead mill homogenizers, which all require a significant capital investment. This work specifically assessed the …

Internal Wave Generation Over Rough, Sloped Topography: An Experimental Study, Lauren Elizabeth Eberly

Theses and Dissertations

Internal waves exist everywhere in stratified fluids - fluids whose density changes with depth. The two largest bodies of stratified fluid are the atmosphere and ocean. Internal waves are generated from a variety of mechanisms. One common mechanism is wind forcing over repeated sinusoidal topography, like a series of hills. When modeling these waves, linear theory has been employed due to its ease and low computational cost. However, recent research has shown that non-linear effects, such as boundary layer separation, may have a dramatic impact on wave generation. This research has consisted of experimentation on sloped, sinusoidal hills. As of …

Comparison Of 3-D Friction Stir Welding Viscoplastic Finite Element Model With Weld Data And Physically-Simulated Data, Maria Posada

Theses and Dissertations

Models (both physical and numerical) of the friction stir (FS) welding process are used to develop a greater understanding of the influence of independent process parameters on dependent process output variables, such as torque, power, specific weld energy, peak temperature, cooling rates and various metallurgical factors (e.g., grain size and precipitates). An understanding of how the independent process parameters influence output variables and ultimately their effect on resultant properties (e.g., strength, hardness, etc..) is desirable. Most models developed have been validated primarily for aluminum alloys with relatively small amounts of experimental data. Fewer models have been validated for steels or …

Two-Refinement By Pillowing For Structured Hexahedral Meshes, J. Bruce Malone

Theses and Dissertations

A number of methods for adaptation of existing all-hexahedral grids by localized refinement have been developed; however, none ideally fit all refinement needs. This thesis presents the structure to a method of two-refinement developed for conformal, structured, all-hexahedral grids that offers flexibility beyond what has been offered to date. The method is fundamentally based on pillowing pairs of sheets of hexes. This thesis also suggests an implementation of the method, shows the results of examples refined using it and compares these results to results from implementing three-refinement on the same examples.