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Articles 991 - 1020 of 11222

Full-Text Articles in Engineering

The Brazilian Soil Spectral Service (Braspecs): A User-Friendly System For Global Soil Spectra Communication, José A. M. Demattê, Ariane Francine Da Silveira Paiva, Raul Roberto Poppiel, Nícolas Augusto Rosin, Luis Fernando Chimelo Ruiz, Fellipe Alcantara De Oliveira Mello, Budiman Minasny, Sabine Grunwald, Yufeng Ge, Eyal Ben Dor, Asa Gholizadeh, Cecile Gomez, Sabine Chabrillat, Nicolas Francos, Shamsollah Ayoubi, Dian Fiantis, James Kobina Mensah Biney, Changkun Wang, Abdelaziz Belal, Salman Naimi, Najmeh Asgari Hafshejani, Henrique Bellinaso, Jean Michel Moura-Bueno, Nélida E. Q. Silvero Jan 2022

The Brazilian Soil Spectral Service (Braspecs): A User-Friendly System For Global Soil Spectra Communication, José A. M. Demattê, Ariane Francine Da Silveira Paiva, Raul Roberto Poppiel, Nícolas Augusto Rosin, Luis Fernando Chimelo Ruiz, Fellipe Alcantara De Oliveira Mello, Budiman Minasny, Sabine Grunwald, Yufeng Ge, Eyal Ben Dor, Asa Gholizadeh, Cecile Gomez, Sabine Chabrillat, Nicolas Francos, Shamsollah Ayoubi, Dian Fiantis, James Kobina Mensah Biney, Changkun Wang, Abdelaziz Belal, Salman Naimi, Najmeh Asgari Hafshejani, Henrique Bellinaso, Jean Michel Moura-Bueno, Nélida E. Q. Silvero

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Although many Soil Spectral Libraries (SSLs) have been created globally, these libraries still have not been operationalized for end-users. To address this limitation, this study created an online Brazilian Soil Spectral Service (BraSpecS). The system was based on the Brazilian Soil Spectral Library (BSSL) with samples collected in the Visible–Near–Short-wave infrared (vis–NIR–SWIR) and Midinfrared (MIR) ranges. The interactive platform allows users to find spectra, act as custodians of the data, and estimate several soil properties and classification. The system was tested by 500 Brazilian and 65 international users. Users accessed the platform (besbbr.com.br), uploaded their spectra, and received soil organic …


Unmanned Aerial System-Based Data Ferrying Over A Sensor Node Station Network In Maize, Jasreman Singh, Yufeng Ge, Derek M. Heeren, Elizabeth Walter-Shea, Christopher M. U. Neale, Suat Irmak, Mitchell S. Maguire Jan 2022

Unmanned Aerial System-Based Data Ferrying Over A Sensor Node Station Network In Maize, Jasreman Singh, Yufeng Ge, Derek M. Heeren, Elizabeth Walter-Shea, Christopher M. U. Neale, Suat Irmak, Mitchell S. Maguire

Department of Agricultural and Biological Systems Engineering: Faculty Publications

© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).


High Throughput Analysis Of Leaf Chlorophyll Content In Sorghum Using Rgb, Hyperspectral, And Fluorescence Imaging And Sensor Fusion, Huichun Zhang, Yufeng Ge, Xinyan Xie, Abbas Atefi, Nuwan Wijewardane,, Suresh Thapa Jan 2022

High Throughput Analysis Of Leaf Chlorophyll Content In Sorghum Using Rgb, Hyperspectral, And Fluorescence Imaging And Sensor Fusion, Huichun Zhang, Yufeng Ge, Xinyan Xie, Abbas Atefi, Nuwan Wijewardane,, Suresh Thapa

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Background: Leaf chlorophyll content plays an important role in indicating plant stresses and nutrient status. Traditional approaches for the quantification of chlorophyll content mainly include acetone ethanol extraction, spectrophotometry and high-performance liquid chromatography. Such destructive methods based on laboratory procedures are time consuming, expensive, and not suitable for high-throughput analysis. High throughput imaging techniques are now widely used for non-destructive analysis of plant phenotypic traits. In this study three imaging modules (RGB, hyperspectral, and fluorescence imaging) were, separately and in combination, used to estimate chlorophyll content of sorghum plants in a greenhouse environment. Color features, spectral indices, and chlorophyll fluorescence …


Maize Response To Irrigation And Nitrogen Under Center Pivot, Subsurface Drip And Furrow Irrigation: Water Productivity, Basal Evapotranspiration And Yield Response Factors, Ali T. Mohammed, Suat Irmak Jan 2022

Maize Response To Irrigation And Nitrogen Under Center Pivot, Subsurface Drip And Furrow Irrigation: Water Productivity, Basal Evapotranspiration And Yield Response Factors, Ali T. Mohammed, Suat Irmak

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Information and data about quantification and comparison of crop water productivity indices for various irrigation levels and methods and nitrogen (N) application timings “simultaneously” under the same conditions do not exist. Unprecedented and extensive field experiments were conducted for maize (Zea mays L.) in 2016 and 2017 under center pivot (CP), subsurface drip irrigation (SDI) and furrow irrigation (FI) methods with full irrigation treatment (FIT), 80% FIT, 60% FIT and rainfed treatment (RFT) with three N application timings. N treatments were: (i) traditional (TN), (ii) non-traditional-1 (NT-1) and (iii) non-traditional-2 (NT-2). Irrigation yield production functions (IYPF); evapotranspiration-yield production functions …


Sources Of Variability And Uncertainty In Food-Energy-Water Nexus Systems, Heydi Calderon-Ambelis, Deepak R. Keshwani Jan 2022

Sources Of Variability And Uncertainty In Food-Energy-Water Nexus Systems, Heydi Calderon-Ambelis, Deepak R. Keshwani

Department of Agricultural and Biological Systems Engineering: Faculty Publications

A nexus approach contributes to the strategic allocation of resources to secure food, energy, and water for the world population. Integrated models considering the complex interactions across food, energy, and water (FEW) enhance decision-making and strategic planning towards resilience. However, a significant number of the existing integrated models leave unaddressed the inherent variability and uncertainty present in the FEW sectors. Here, we review the importance of characterizing variability over spatial and temporal scales and the importance of decreasing the uncertainty present within a FEW nexus systems. The review also discusses existing modeling tools that address variability and uncertainty on single …


Modeling Water Quantity And Quality Nonlinearities For Watershed Adaptability To Hydroclimate Extremes In Agricultural Landscapes, Juan Carlos Jaimes-Correa, Francisco Muñoz-Arriola, Shannon Bartelt-Hunt Jan 2022

Modeling Water Quantity And Quality Nonlinearities For Watershed Adaptability To Hydroclimate Extremes In Agricultural Landscapes, Juan Carlos Jaimes-Correa, Francisco Muñoz-Arriola, Shannon Bartelt-Hunt

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Changing water supplies and demands, inherent to climate fluctuations and human activities, are pushing for a paradigm shift in water management worldwide. The occurrence of extreme hydrometeorological and climate events such as extended wet periods and droughts, compounded with contaminants, impair the access to water resources, demanding novel designs, construction, and management across multiple hydrologic scales and biogeochemical processes. A constraint to studying hydrologic and biogeochemical disturbances and improving best management practices for water quantity and quality at the watershed scale resides in the suitable monitoring, data availability, and the creation of frameworks. We hypothesize that streamflow and contaminants, simulated …


Comparison Effect On Biogas Production From Vegetable And Fruit Waste With Rumen Digesta Through Co-Digestion Process, Anika Tasnim, Muhammad Rashed Al Mamun, Md Anwar Hossen, Md Towfiqur Rahman, Md Janibul Alam Soeb Jan 2022

Comparison Effect On Biogas Production From Vegetable And Fruit Waste With Rumen Digesta Through Co-Digestion Process, Anika Tasnim, Muhammad Rashed Al Mamun, Md Anwar Hossen, Md Towfiqur Rahman, Md Janibul Alam Soeb

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Biogas is the best renewable energy as it can be produced from any biomass for example any plant or living organism. The purpose of this research was to produce biomethane from co-digestion of vegetable and fruit waste with rumen digesta through anaerobic digestion process. In this research, two trials of experiment were conducted. Each trial has three different sample with different mixing ratios. Raw materials used in the experiment was rumen digesta of goat and cow, potato, capsicum, cucumbers, onions, radish, cauliflower, carrot, leafy vegetables, apple, banana, and papaya. In each sample, 1200 gram of raw materials were used. Hydraulic …


Influences Of Artificial Light On Mating Of Black Soldier Fly (Hermetia Illucens): A Review, Md Rabiul Awal, Md Masudur Rahman, Md Abdur Razzak Choudhury, Md Mehedi Hasan, Md Towfiqur Rahman, Md Fuad Mondal Jan 2022

Influences Of Artificial Light On Mating Of Black Soldier Fly (Hermetia Illucens): A Review, Md Rabiul Awal, Md Masudur Rahman, Md Abdur Razzak Choudhury, Md Mehedi Hasan, Md Towfiqur Rahman, Md Fuad Mondal

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Black soldier fly (Hermetia illucens) is a potential insect species which can convert biodegradable materials and some indigestible organic waste into valuable biomass. Because of having good quality of fat and protein, its production and use in animal feed are being extended day by day. To fulfill the future demand re-searchers are trying to find out the successful mass rearing techniques of H. illucens in laboratory or indoor condition. However, the most critical part of H. illucens mass production is obtaining successful mating. This insect is very sensitive to light. It prefers direct sunlight for its …


Geospatial Distribution Of Age-Adjusted Incidence Of The Three Major Types Of Pediatric Cancers And Waterborne Agrichemicals In Nebraska, Balkissa S. Ouattara, Jagadeesh Puvvula, Azar Abadi, Siddhi Munde, Alan S. Kolok, Shannon Bartelt-Hunt, Jesse E. Bell, Christopher S. Wichman, Eleanor Rogan Jan 2022

Geospatial Distribution Of Age-Adjusted Incidence Of The Three Major Types Of Pediatric Cancers And Waterborne Agrichemicals In Nebraska, Balkissa S. Ouattara, Jagadeesh Puvvula, Azar Abadi, Siddhi Munde, Alan S. Kolok, Shannon Bartelt-Hunt, Jesse E. Bell, Christopher S. Wichman, Eleanor Rogan

Department of Civil and Environmental Engineering: Faculty Publications

This study was conducted to examine, at the county level, the relationship between pediatric cancer incidence rate and atrazine and nitrate mean concentrations in surface and groundwater. A negative binomial regression analysis was performed to investigate the association between central nervous system (CNS) tumors, leukemia, lymphoma, and atrazine and nitrate mean concentrations in groundwater. The age-adjusted brain and other CNS cancer incidence was higher than the national average in 63% of the Nebraska counties. After controlling for the counties socio-economic status and nitrate concentrations in groundwater, counties with groundwater atrazine concentrations above 0.0002 μg/L had a higher incidence rate for …


Probability-Based Crack Width Estimation Model For Flexural Members Of Underground Rc Box Culverts, Sang-Hyo Kim, Syed Haider Ali Shah, Sang-Kyun Woo, Inyeop Chu, Chungwook Sim Jan 2022

Probability-Based Crack Width Estimation Model For Flexural Members Of Underground Rc Box Culverts, Sang-Hyo Kim, Syed Haider Ali Shah, Sang-Kyun Woo, Inyeop Chu, Chungwook Sim

Department of Civil and Environmental Engineering: Faculty Publications

Crack control for slabs and beams in current design practices in Korea are based on the Frosch’s model, which is adapted in ACI 318. It is more difficult to have consistent quality control in underground construction sites, such as the RC box culverts used for electric power distribution built below the ground level. There are more discrepancies between the as-built dimensions and the design dimensions provided in drawings in these structures. Due to this variability in construction error, the crack widths measured in such structures have higher potential to have more differences than the calculated values. Although crack control is …


Recent Advances In Biosensors For Detection Of Covid-19 And Other Viruses, Shobhit K. Patel, Jaymit Surve, Juveriya Parmar, Kawsar Ahmed, Francis M. Bui, Fahad Ahmed Al-Zahrani Jan 2022

Recent Advances In Biosensors For Detection Of Covid-19 And Other Viruses, Shobhit K. Patel, Jaymit Surve, Juveriya Parmar, Kawsar Ahmed, Francis M. Bui, Fahad Ahmed Al-Zahrani

Department of Mechanical and Materials Engineering: Faculty Publications

This century has introduced very deadly, dangerous, and infectious diseases to humankind such as the influenza virus, Ebola virus, Zika virus, and the most infectious SARS-CoV-2 commonly known as COVID-19 and have caused epidemics and pandemics across the globe. For some of these diseases, proper medications, and vaccinations are missing and the early detection of these viruses will be critical to saving the patients. And even the vaccines are available for COVID-19, the new variants of COVID-19 such as Delta, and Omicron are spreading at large. The available virus detection techniques take a long time, are costly, and complex and …


A Robot-Assisted Acoustofluidic End Effector, Jan Durrer, Prajwal Agrawal, Ali Ozgul, Stephen C.F. Neuhauss, Nitesh Nama, Daniel Ahmed Jan 2022

A Robot-Assisted Acoustofluidic End Effector, Jan Durrer, Prajwal Agrawal, Ali Ozgul, Stephen C.F. Neuhauss, Nitesh Nama, Daniel Ahmed

Department of Mechanical and Materials Engineering: Faculty Publications

Liquid manipulation is the foundation of most laboratory processes. For macroscale liquid handling, both do-it-yourself and commercial robotic systems are available; however, for microscale, reagents are expensive and sample preparation is difficult. Over the last decade, lab-on-a-chip (LOC) systems have come to serve for microscale liquid manipulation; however, lacking automation andmulti-functionality. Despite their potential synergies, each has grown separately and no suitable interface yet exists to link macro-level robotics with micro-level LOC or microfluidic devices. Here, we present a robot-assisted acoustofluidic end effector (RAEE) system, comprising a robotic arm and an acoustofluidic end effector, that combines robotics and microfluidic functionalities.We …


The Third International Hackathon For Applying Insights Into Large-Scale Genomic Composition To Use Cases In A Wide Range Of Organisms, Kimberly Walker, Divya Kalra, Rebecca Lowdon, Guangyi Chen, Fritz J. Sedlazeck, Ben Busby, Chia-Sin Liew, Et Al. Jan 2022

The Third International Hackathon For Applying Insights Into Large-Scale Genomic Composition To Use Cases In A Wide Range Of Organisms, Kimberly Walker, Divya Kalra, Rebecca Lowdon, Guangyi Chen, Fritz J. Sedlazeck, Ben Busby, Chia-Sin Liew, Et Al.

Nebraska Center for Biotechnology: Faculty and Staff Publications

In October 2021, 59 scientists from 14 countries and 13 U.S. states collaborated virtually in the Third Annual Baylor College of Medicine & DNANexus Structural Variation hackathon. The goal of the hackathon was to advance research on structural variants (SVs) by prototyping and iterating on open-source software. This led to nine hackathon projects focused on diverse genomics research interests, including various SV discovery and genotyping methods, SV sequence reconstruction, and clinically relevant structural variation, including SARS-CoV-2 variants. Repositories for the projects that participated in the hackathon are available at https://github.com/collaborativebioinformatics.


Comparison Of Stationary And Mobile Canopy Sensing Systems For Irrigation Management Of Maize And Soybean In Nebraska, Sandeep Bhatti, Derek M. Heeren, Susan A. O’Shaughnessy, Steven R. Evett, Mitchell S Maguire, Suresh Pradhyun Kashyap, Christopher M. U. Neale Jan 2022

Comparison Of Stationary And Mobile Canopy Sensing Systems For Irrigation Management Of Maize And Soybean In Nebraska, Sandeep Bhatti, Derek M. Heeren, Susan A. O’Shaughnessy, Steven R. Evett, Mitchell S Maguire, Suresh Pradhyun Kashyap, Christopher M. U. Neale

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Accurate knowledge of plant and field characteristics is crucial for irrigation management. Irrigation can potentially be better managed by utilizing data collected from various sensors installed on different platforms. The accuracy and repeatability of each data source are important considerations when selecting a sensing system suitable for irrigation management. The objective of this study was to compare data from multispectral (red and near-infrared bands) and thermal (long wave thermal infrared band) sensors mounted on different platforms to investigate their comparative usability and accuracy. The different sensor platforms included stationary posts fixed on the ground, the lateral of a center pivot …


Inspiring Young Students To Pursue Engineering, Tami M. Brown-Brandl, Brian Steward Jan 2022

Inspiring Young Students To Pursue Engineering, Tami M. Brown-Brandl, Brian Steward

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Imagine elementary school students understanding inputs and outputs, choosing appropriate sensors, and programming an autonomous robot. Imagine middle school students learning about PID control and creating advanced programs for sensor-based decision making. Imagine high school students using CAD to design drive trains, manufacturing parts with CNC machine tools, using finite element analysis to adjust the design, ordering custom components from a machine shop, using image processing for target recognition, and applying path planning and motion control. We have witnessed all of these skills. They happened outside of traditional classrooms, and they were all student-driven.

Yes, it’s true, and it’s amazing. …


Cive 440: Reinforced Concrete Design I: Faculty-Led Inquiry Into Reflective And Scholarly Teaching (First) Course Portfolio, Chungwook Sim Jan 2022

Cive 440: Reinforced Concrete Design I: Faculty-Led Inquiry Into Reflective And Scholarly Teaching (First) Course Portfolio, Chungwook Sim

UNL Faculty Course Portfolios

This Faculty-led Inquiry into Reflective and Scholarly Teaching (FIRST) Course Portfolio documents the instructor’s teaching practices and student learning for Reinforced Concrete Design I (CIVE 440) course. The contents of this course portfolio captures the CIVE 440 course that was taught on the Lincoln campus during the semester of Fall 2022. CIVE 440 is a structural engineering design elective offered every year in the Department of Civil and Environmental Engineering on both Lincoln and Omaha campus at University of Nebraska-Lincoln (UNL). The course objective is to help students to be able to use theory and experience to proportion and detail …


Research On High-Rap Mixtures With Rejuvenator - Field Implementation, Nitish R. Bastola, Mahdieh Khedmati, Hamzeh Haghshenas Dec 2021

Research On High-Rap Mixtures With Rejuvenator - Field Implementation, Nitish R. Bastola, Mahdieh Khedmati, Hamzeh Haghshenas

Nebraska Department of Transportation: Research Reports

The use of Rejuvenating Agents (RAs), as Recycled Asphalt Pavement (RAP) modifiers, has been increasing over the past years. However, the field performance of asphalt mixtures containing high-RAP materials and modified with RAs has raised some concerns regarding the long-term performance of RAs. This study evaluated the laboratory and field performance of high-RAP mixtures with and without bio-oil RA. Three sets of plant-produced specimens were collected: 1) laboratory-compacted; 2) field-compacted and cored after paving; and 3) field-compacted and cored after one and two years. The Hamburg Wheel Tracking (HWT) test was used to evaluate the specimens' resistance to rutting and …


Substrate Delivery Of Embedded Liposomes, Srivatsan Kidambi, Stephen L. Hayward Dec 2021

Substrate Delivery Of Embedded Liposomes, Srivatsan Kidambi, Stephen L. Hayward

Department of Chemical and Biomolecular Engineering: Faculty Publications

This invention relates to compositions useful for localized and sustained release of therapeutic agents, and more particularly to functionalized liposomes embedded in a poly electrolyte multilayer. Methods of preparing the compositions, methods of treating diseases, devices, and pharmaceutical compositions comprising the compositions are also provided.


Low-Level Groundwater Atrazine In High Atrazine Usage Nebraska Counties: Likely Effects Of Excessive Groundwater Abstraction, Moses New-Aaron, Olufemi P. Abimbola, Raheleh Mohammadi, Oluwaseun Famojuro, Zaeema Naveed, Azar M Abadi, Jesse E. Bell, Shannon Bartelt-Hunt, Eleanor G. Rogan Dec 2021

Low-Level Groundwater Atrazine In High Atrazine Usage Nebraska Counties: Likely Effects Of Excessive Groundwater Abstraction, Moses New-Aaron, Olufemi P. Abimbola, Raheleh Mohammadi, Oluwaseun Famojuro, Zaeema Naveed, Azar M Abadi, Jesse E. Bell, Shannon Bartelt-Hunt, Eleanor G. Rogan

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Recent studies observed a correlation between estrogen-related cancers and groundwater atrazine in eastern Nebraska counties. However, the mechanisms of human exposure to atrazine are unclear because low groundwater atrazine concentration was observed in counties with high cancer incidence despite having the highest atrazine usage. We studied groundwater atrazine fate in high atrazine usage Nebraska counties. Data were collected from Quality Assessed Agrichemical Contaminant Nebraska Groundwater, Parameter–Elevation Regressions on Independent Slopes Model (PRISM), and water use databases. Descriptive statistics and cluster analysis were performed. Domestic wells (59%) were the predominant well type. Groundwater atrazine was affected by well depth. Clusters consisting …


Gis-Based Volunteer Cotton Habitat Prediction And Plant-Level Detection With Uav Remote Sensing, Tianyi Wang, Xiaohan Mei, J. Alex Thomasson, Chenghai Yang, Xiongzhe Han, Pappu Kumar Yadav, Yeyin Shi Dec 2021

Gis-Based Volunteer Cotton Habitat Prediction And Plant-Level Detection With Uav Remote Sensing, Tianyi Wang, Xiaohan Mei, J. Alex Thomasson, Chenghai Yang, Xiongzhe Han, Pappu Kumar Yadav, Yeyin Shi

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Volunteer cotton plants germinate and grow at unwanted locations like transport routes and can serve as hosts for a harmful cotton pests called cotton boll weevils. The main objective of this study was to develop a geographic information system (GIS) framework to efficiently locate volunteer cotton plants in the cotton production regions in southern Texas, thus reducing time and economic cost for their removal. A GIS network analysis tool was applied to estimate the most likely routes for cotton transportation, and a GIS model was created to identify and visualize potential areas of volunteer cotton growth. The GIS model indicated …


Source Apportionment And Health Risk Assessment Of Nitrate In Foothill Aquifers Of Western Ghats, South India, Banajarani Panda, S. Chidambaram, Daniel D. Snow, Arindam Malakar, Dhiraj Kr Singh, L. Ramanathan Dec 2021

Source Apportionment And Health Risk Assessment Of Nitrate In Foothill Aquifers Of Western Ghats, South India, Banajarani Panda, S. Chidambaram, Daniel D. Snow, Arindam Malakar, Dhiraj Kr Singh, L. Ramanathan

Nebraska Water Center: Faculty Publications

The present research reports the level of nitrate (NO3-), associated health risks and possible sources of contamination in groundwater from south India. Many samples (32%) are above or approaching the recommended level of NO3- for safe drinking water. The correlation analysis indicates different sources of NO3- contamination in different regions rather than a common origin. The isotopic measurements provide information about potential nitrogen sources contributing NO3- to the groundwater. Based on isotope analysis, the sources of NO3- in the groundwater of this region are likely to be from (a) …


Smooth Muscle Cells Affect Differential Nanoparticle Accumulation In Disturbed Blood Flow-Induced Murine Atherosclerosis, Hunter Miller, Morgan A. Schake, Badrul Alam Bony, Evan T. Curtis, Conner C. Gee, Ian Mccue, Thomas J. Ripperda Jr., Yiannis S. Chatzizisis, Forrest Kievit, Ryan M. Pedrigi Dec 2021

Smooth Muscle Cells Affect Differential Nanoparticle Accumulation In Disturbed Blood Flow-Induced Murine Atherosclerosis, Hunter Miller, Morgan A. Schake, Badrul Alam Bony, Evan T. Curtis, Conner C. Gee, Ian Mccue, Thomas J. Ripperda Jr., Yiannis S. Chatzizisis, Forrest Kievit, Ryan M. Pedrigi

Department of Mechanical and Materials Engineering: Faculty Publications

Atherosclerosis is a lipid-driven chronic inflammatory disease that leads to the formation of plaques in the inner lining of arteries. Plaques form over a range of phenotypes, the most severe of which is vulnerable to rupture and causes most of the clinically significant events. In this study, we evaluated the efficacy of nanoparticles (NPs) to differentiate between two plaque phenotypes based on accumulation kinetics in a mouse model of atherosclerosis. This model uses a perivascular cuff to induce two regions of disturbed wall shear stress (WSS) on the inner lining of the instrumented artery, low (upstream) and multidirectional (downstream), which, …


Microfabricated Platforms To Investigate Cell Mechanical Properties, Amir M. Esfahani, Grayson Minnick, Jordan Rosenbohm, Haiwei Zhai, Xiaowei Jin, Bahareh Tajvidi Safa, Justin Brooks, Ruiguo Yang Dec 2021

Microfabricated Platforms To Investigate Cell Mechanical Properties, Amir M. Esfahani, Grayson Minnick, Jordan Rosenbohm, Haiwei Zhai, Xiaowei Jin, Bahareh Tajvidi Safa, Justin Brooks, Ruiguo Yang

Department of Mechanical and Materials Engineering: Faculty Publications

Mechanical stimulation has been imposed on living cells using several approaches. Most early investigations were conducted on groups of cells, utilizing techniques such as substrate deformation and flow-induced shear. To investigate the properties of cells individually, many conventional techniques were utilized, such as AFM, optical traps/optical tweezers, magnetic beads, and micropipette aspiration. In specific mechanical interrogations, microelectro- mechanical systems (MEMS) have been designed to probe single cells in different interrogation modes. To exert loads on the cells, these devices often comprise piezo-electric driven actuators that attach directly to the cell or move a structure on which cells are attached. Uniaxial …


Injectable Decellularized Nucleus Pulposus Tissue Exhibits Neuroinhibitory Properties, Logan M. Piening, David J. Lillyman, Fei San Lee, Alvaro Moreno Lozano, Jeremy R. Miles, Rebecca A. Wachs Dec 2021

Injectable Decellularized Nucleus Pulposus Tissue Exhibits Neuroinhibitory Properties, Logan M. Piening, David J. Lillyman, Fei San Lee, Alvaro Moreno Lozano, Jeremy R. Miles, Rebecca A. Wachs

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Background: Chronic low back pain (LBP) is a leading cause of disability, but treatments for LBP are limited. Degeneration of the intervertebral disc due to loss of neuroinhibitory sulfated glycosaminoglycans (sGAGs) allows nerves from dorsal root ganglia to grow into the core of the disc. Treatment with a decellularized tissue hydrogel that contains sGAGs may inhibit nerve growth and prevent discassociated LBP.

Methods: A protocol to decellularize porcine nucleus pulposus (NP) was adapted from previous methods. DNA, sGAG, α-gal antigen, and collagen content were analyzed before and after decellularization. The decellularized tissue was then enzymatically modified to be …


Global Analysis Of Differential Gene Expression Within The Porcine Conceptus Transcriptome As It Transitions Through Spherical, Ovoid, And Tubular Morphologies During The Initiation Of Elongation, Sophie C. Walsh, Jeremy R. Miles, Brittney N. Keel, Lea A. Rempel, Elane C. Wright‐Johnson, Amanda K. Lindholm‐Perry, William T. Oliver, Angela K. Pannier Dec 2021

Global Analysis Of Differential Gene Expression Within The Porcine Conceptus Transcriptome As It Transitions Through Spherical, Ovoid, And Tubular Morphologies During The Initiation Of Elongation, Sophie C. Walsh, Jeremy R. Miles, Brittney N. Keel, Lea A. Rempel, Elane C. Wright‐Johnson, Amanda K. Lindholm‐Perry, William T. Oliver, Angela K. Pannier

Department of Agricultural and Biological Systems Engineering: Faculty Publications

This study aimed to identify transcriptome differences between distinct or transitional stage spherical, ovoid, and tubular porcine blastocysts throughout the initiation of elongation. We performed a global transcriptome analysis of differential gene expression using RNA‐Seq with high temporal resolution between spherical, ovoid, and tubular stage blastocysts at specific sequential stages of development from litters containing conceptus populations of distinct or transitional blastocysts. After RNA‐Seq analysis, significant differentially expressed genes (DEGs) and pathways were identified between distinct morphologies or sequential development stages. Overall, 1898 significant DEGs were identified between distinct spherical and ovoid morphologies, with 311 total DEGs between developmental stages …


Irrigation Systems Management, Dean Eisenhauer, Derrel L. Martin, Derek M. Heeren, Glenn J. Hoffman Dec 2021

Irrigation Systems Management, Dean Eisenhauer, Derrel L. Martin, Derek M. Heeren, Glenn J. Hoffman

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Management of irrigation systems should be based on the desired objectives or outcomes consistent with economic, energy, environmental, labor, water, and resource constraints. Goals can vary from maximizing profit, producing a contracted yield, optimizing water resource use, maintaining the quality of produce, or assuring an attractive landscape. Managers cannot achieve these goals without considering the performance of the irrigation system. This chapter discusses the basic characteristics of various irrigation systems, defines terms that quantify performance, describes basic requirements all systems must provide, gives a range of attributes for systems, and discusses how water supply requirements are governed by ET and …


Irrigation Systems Management, Dean E. Eisenhauer, Derrel L. Martin, Derek M. Heeren, Glenn J. Hoffman Dec 2021

Irrigation Systems Management, Dean E. Eisenhauer, Derrel L. Martin, Derek M. Heeren, Glenn J. Hoffman

Open Educational Resources: Textbooks

Like most textbooks, this book grew out of our desire to have written material that matches the educational needs of both the students and the instructor of a college course, in this case a course entitled Irrigation Systems Management. The book is the culmination of course notes which have been in development and use for nearly 30 years.

The emphasis of this book is on the management of irrigation systems that are used for agricultural crop production. There are two distinct components of the book, starting with the soil-water-plant-atmosphere system and how soil water should be managed to achieve the …


Novel Approaches For Enhancing Cell Survival And Function In Vivo, Ou Wang Dec 2021

Novel Approaches For Enhancing Cell Survival And Function In Vivo, Ou Wang

Department of Chemical and Biomolecular Engineering: Dissertations, Theses, and Student Research

FDA has approved several cell-based therapeutics and hundreds of cell therapy clinical trials are ongoing. Cells will be a significant type of medicine after small molecule and protein drugs. However, several obstacles need to be addressed to achieve the widespread use of cellular therapeutics. The first challenge is the low efficacy of cell transplantation due to low retention, survival, integration, and function of cells in vivo. The second challenge is producing a massive number of cells for clinical treatment with cost-effectively and reproducibly technologies.

In this thesis, we proposed and investigated two approaches to address these challenges. To begin …


Computational Solutions To Exosomal Microrna Biomarker Detection In Pancreatic Cancer, Thuy T. An Dec 2021

Computational Solutions To Exosomal Microrna Biomarker Detection In Pancreatic Cancer, Thuy T. An

School of Computing: Dissertations, Theses, and Student Research

Pancreatic cancer is the fourth leading cause of cancer death in the United States and the 5-year survival rate is only 5% to 10%. There are only a few non-specific symptoms associated with the early-stage cancer, therefore most patients are diagnosed in a late stage. Due to the lack of effective treatments and the fact that the early stage has a 39% 5-year survival rate, the biggest hope to control this disease is early detection. Therefore, discovery of effective and reliable non-invasive biomarkers for early detection of pancreatic cancer has been a major topic. Very recently, exosomal microRNAs have become …


The Application Of Mathematical Optimization And Flavor-Detection Technologies For Modeling Aroma Of Hops, Yutong Liu Dec 2021

The Application Of Mathematical Optimization And Flavor-Detection Technologies For Modeling Aroma Of Hops, Yutong Liu

Department of Food Science and Technology: Dissertations, Theses, and Student Research

In recent years, proprietary hops (Citra, Simcoe, and Mosaic) become the most sought-after hops among brewers due to their excellent aroma. However, they are restricted to the owners unless other growers purchase the costly licensing agreements. Many public hops are available to the growers without any additional costs, but their aroma is difficult to match to the proprietary hops. Although proprietary and public hop varieties are unique in their aroma profiles, all hops varieties contain similar volatile compounds, merely differ in the quantity of different individual compounds. The main objective of this thesis was to investigate the feasibility of matching …