Engineering Commons^™

Design Of Drug Delivery Strategies Based On Well-Stirred Experiments, Kumud Kanneganti

Theses

Drugs are generally administered to the human body via injections (IV) or through other paths such as the buccal, nasal routes. The main consideration when designing a medication schedule is to maintain a therapeutic level of the drug in the body during the course of treatment. To achieve this goal, when IV drug therapy is selected, particular importance has to given to the dose to be injected and how to maintain the concentration of the pharmaceutical active ingredient (API) in the body between a Minimum Toxic Concentration (MTC) and a Minimum Effective Concentration (MEC). This therapeutic range varies with the …

A Study Of Probability Distributions Of Dct Coefficients In Jpeg Compression, Gopal Thirumalai Narayanan

Theses

The Discrete Cosine Transform (DCT) used in JPEG compression has shown excellent energy compaction properties that rival that of the ideal Karhunen-Loève Transform. Lossy compression in JPEG is achieved by distorting 8x8 block DCT coefficients through quantization. It has been shown in literature that DC block DCT coefficients are Gaussian probability distributed and AC block DCT coefficients are Generalized Normal probability distributed.

In this investigation, three probability density models for individual modes of non- quantized AC block DCT coefficients are evaluated and are used as basis for the derivation of probability distributions for quantized block DCT coefficients. The suitability of …

Exploiting The Concept Of Hysteresis In Ankle Dysfunction And Ankle Strengthening, Akshay Narendra Pujara

Theses

The ankle joint is an important part of the body which is responsible for normal gait cycle. Dorsiflexion, plantar flexion, inversion and eversion are four types of movements controlled by the ankle joint. All these movements are controlled by the ligaments and the muscles associated with the ankle. Disorders of these ligaments and muscles leads to ankle dysfunction.

The hysteresis concept was employed to determine if there is any ankle dysfunction. A recently developed device, the Ankle Torsion Monitor (AnTm) was employed to evaluate the viscoelasticity and stiffness of the ankle joint. The greater the hysteresis loop area (HLA) the …

Automation Of Anatomic Torsion Monitor For Evaluation And Improvement Of Low Back Dysfunction, Vishal Kumar Singh

Theses

The existing Anatomical Torsion Monitor (ATM) to evaluate mechanical stiffness and viscoelasticity of the low back suffers from various inherent defects. This has to be replaced by an improved device. Also the existing ATM cannot provide oscillations to the low back.

The main objective is to automate the existing ATM for evaluating the low back immediately using objective methods. The specific objective is to provide oscillations for improving the low back dysfunction.

The laser platform and the target chart for recording the readings are dispensed with the existing ATM. Instead, the ultrasound transducers are attached to the pads to record …

A Comparison Of Software Engines For Simulation Of Closed-Loop Control Systems, Sanket D. Nikam

Theses

A wide array of control system design and simulation software engines is available in market. It includes MATLAB-Simulink, LabVIEW, Maple-MapleSim, Scilab-Scicos, VisSim and Mathematica-Control Professional Suite (CPS). Among all of them MATLAB-Simulink is dominant and widely used software engine. The main aim of this study is to implement different state space control methods for non-linear Furuta pendulum system in each one of them and to compare performance against MATLAB-Simulink.

Different parameters like learning curve, interoperability, flexibility, control design tools, documentation and tech support are considered for efficiency comparison. It is shown that MapleSim has multi-body intuitive physical modeling (acausal) approach …

Axon Guided Axon Growth In Drg Neurons From The Spinal Cord Of Rat Embryos, Neha Jain

Theses

Early studies in the area of neuronal physiology and injury have shown that axons are guided by a number of physical as well as chemical cues. Although the guidance effect of initial axons and their processes on later axons has been shown from a development point of view, little light has been thrown on the subject from the injury point of view. This important ability of axons which plays a key role during development and formation of neuronal networks could become crucial in repairing damaged nerves and disrupted neuronal tracts.

In the following study, the guidance effect of an older …

Power Flow In Railway Electrification Power System, Sisi Li

Theses

This thesis discusses aspects of the design of the railway electrification system (RES) and in particular the electric distribution system for a 2x25 kV railway power system.

The analysis of Railway Power Supplies (RPS) presents a unique type of load flow problem which is characterized by its constant moving loads, dynamically changing load types (constant current/constant power), and its specialized network structure. The autotransformer power supply system with double track was the system studied in this thesis.

The details of the system studied were provided by Caltrain (California Commuter Rail) for a planned high speed extension to Caltrain system. A …

Study Of Methods To Predict Voltage Collapse, Niki Patel

Theses

One of the problems that must be addressed for a secure power system operation is the voltage collapse problem. The ever increasing size and connectivity of the power grid have lead to making the problem more multifarious. Widespread blackouts, similar to the one that occurred in the northeast in August 2003, could result from failure to address the problem.

This thesis presents an overview of the voltage collapse problem and reviews some existing methods to calculate voltage collapse indicators.

Thevenin and Maximum Power Transfer Theorems are used to provide indicators of the proximity of the system to voltage collapse. The …

Air Piston Approach To Wave Power Generation, Arun Ramadass

Theses

Scientists have calculated that, by tapping just 0.2% of the energy produced by the world's oceans we can provide for all the worlds current energy needs. It is generally accepted that a combination of traditional energy production methods, (oil, coal, gas, nuclear) mixed with a combination of renewable energy production approaches is the future in providing for an increasingly energy hungry world. Wind, solar and biomass have moved into the public arena only in the last few years.

The proposed patented device (US Patent No.: 7,468,563) Ocean Wave Energy Converter harnesses the energy of ocean waves by continually raising and …

Minimum Agitation Speed For Solid Suspension And Mixing Time In A Torispherical -Bottomed Pharmaceutical Stirred Tank Under Different Baffling Conditions, Dilanji Bhagya Wijayasekara

Theses

The minimum agitation speed, NS, required to just suspend solid particles dispersed in water was experimentally determined in this work for a glass-lined type of mixing tank provided with a torispherical bottom and agitated with a retreat-blade impeller under different baffling configurations. Ns for the same tank but equipped with a different agitation system, namely an axial impeller, was also experimentally determined for the purpose of comparing of performances of the two systems. The effect of impeller off- bottom clearance and the vessel's liquid level on the minimum agitation speed were also experimentally studied. Njs, was experimentally determined …

Papr Reduction In Ofdm Communications With Generalized Discrete Fourier Transform, Sertac Sayin

Theses

The main advantage of Generalized Discrete Fourier Transform (GDFT) is its ability to design a wide selection of constant modulus orthogonal code sets, based on the desired performance metrics mimicking the engineering specs of interest. One of the main drawbacks of Orthogonal Frequency Division Multiplexing (OFDM) systems is the high Peak to Average Power Ratio (PAPR) value which is directly related to power consumption of the system. Discrete Fourier Transform (DFT) spread OFDM technology, also known as Single Carrier Frequency Division Multiple Access (SCFDMA), which has a lower PAPR value, is used for uplink channel.

In this thesis, the PAPR …

Stochastic And Deterministic Dynamics Investigation Of The Microstructure Of Granular Materials, Vishagan Ratnaswamy

Theses

Granular materials are ubiquitous in one's daily life. They can be found in the cereal you eat, the sugar you put in your coffee or the sand you walk on in the beach. The study of granular materials has a rich history dating back to the 17th century where Kepler studied the packing of particles. The compaction of granular materials is a problem that is studied by using theory, experiments and simulations. While these studies have yielded some important results, there still are many details about the mechanisms of granular compaction that are unknown.

In this thesis, the density relaxation …

A Fpga/Dsp Based Ultrasound System For Tumor Detection, Ashish Ravindra Ratnakar

Theses

This work presents a method of detection of size and location of tumor using ultrasound transmission. The system utilizes Quantitative Ultrasound (QUS) which means sending an ultrasound signal from a transmitter and receiving it at multiple receivers. This received signal is analyzed for echogenic as well as echolucent tumors to differentiate between the two along with non-tumorous sample and also for delay, signal distortion to determine the size/location of the tumor.

This analysis is further implemented using Field Programmable Gate Array (FPGA) and Digital Signal Processor (DSP) technologies. The proposed detection system utilizes Low Transient Pulse (LTP) technique. In this …

Comparison Between Different Techniques Of Preprocessing For Resting State Fmri Analysis, Megha Girdhar

Theses

Resting state functional connectivity as the name suggests is defined as significant temporal correlation between spatially distinct regions of the brain during rest. In this thesis, fMRI resting state dataset was analyzed using different available processing techniques with the same fMRI data to study differences between the various methods. All the imaging data from each of the subjects was processed in an identical fashion. The same method was used for detecting connectivity. The number of independent components in the data was used as the base to differentiate the effect of each of these methods. Independent component analysis was performed on …

Interfacially Polymerized Thin Film Composite Membranes On Microporous Polypropylene Supports For Reverse Osmosis Desalination, Chao Li

Theses

The important technique of interfacial polymerization (IP) is used to fabricate thin film composite (TFC) membranes. In experiments here, microporous polypropylene (PP) flat film membranes were used as a support for fabricating TFC membranes for reverse osmosis by the IP technique. Substantial chemical, pH, and solvent resistance is provided by porous polypropylene membranes. Therefore, it is reasonable to choose porous polypropylene membranes as supports to fabricate TFC membranes for reverse osmosis.

The external and the pore surfaces of polypropylene flat film membrane were hydrophilized first by pre-wetting with acetone, then oxidized with chromic acid solution kept at 65°C. Next, the …

Target Localization In Mimo Radar Systems, Hana Godrich

Dissertations

MIMO (Multiple-Input Multiple-Output) radar systems employ multiple antennas to transmit multiple waveforms and engage in joint processing of the received echoes from the target. MIMO radar has been receiving increasing attention in recent years from researchers, practitioners, and funding agencies. Elements of MIMO radar have the ability to transmit diverse waveforms ranging from independent to fully correlated. MIMO radar offers a new paradigm for signal processing research. In this dissertation, target localization accuracy performance, attainable by the use of MIMO radar systems, configured with multiple transmit and receive sensors, widely distributed over an area, are studied. The Cramer-Rao lower bound …

Operating Characteristics Of Passenger Screening Processes And The Development Of A Paced Inspection System, Geraldine Kelly Leone

Dissertations

The airport checkpoint security screening (ACSS) system is an important line of defense against the introduction of dangerous objects into the U.S. aviation system. Recently, there has been much interest in modeling these systems and to derive operating parameters which optimize performance. In general there are two performance measures of interest (i) the waiting time of the arriving entities, and (ii) the allocated screening resources and its utilization. Clearly, the traveling public would like a zero waiting time, while airports are limited both in terms of space and resource capital. The arrival and exit entity in the ACSS system are …

Service Oriented Networking For Multimedia Applications In Broadband Wireless Networks, Ehsan Haghani Dogaheh

Dissertations

Extensive efforts have been focused on deploying broadband wireless networks. Providing mobile users with high speed network connectivity will let them run various multimedia applications on their wireless devices. In order to successfully deploy and operate broadband wireless networks, it is crucial to design efficient methods for supporting various services and applications in broadband wireless networks. Moreover, the existing "access-oriented" networking solutions are not able to fully address all the issues of supporting various applications with different quality of service requirements. Thus, "service-oriented" networking has been recently proposed and has gained much attention.

This dissertation discusses the challenges and possible …

Optimal Train Control On Various Track Alignments Considering Speed And Schedule Adherence Constraints, Kitae Kim

Dissertations

The methodology discussed in this dissertation contributes to the field of transit operational control to reduce energy consumption. Due to the recent increase in gasoline cost, a significant number of travelers are shifting from highway modes to public transit, which also induces higher transit energy consumption expenses.

This study presents an approach to optimize train motion regimes for various track alignments, which minimizes total energy consumption subject to allowable travel time, maximum operating speed, and maximum acceleration/deceleration rates. The research problem is structured into four cases which consist of the combinations of track alignments (e.g., single vertical alignment and mixed …

Resource Assignment In Short Life Technology Intensive (Slti) New Product Development (Npd), Randy A. Reagan

Dissertations

Enterprises managing multiple concurrent New Product Development (NPD) projects face significant challenges assigning staff to projects in order to achieve launch schedules that maximize financial returns. The challenge is increased with the class of Short Life Technology Intensive (SLTI) products characterized by technical complexity, short development cycles and short revenue life cycles. Technical complexity drives the need to assign staffing resources of various technical disciplines and skill levels. SLTI products are rapidly developed and launched into stationary market windows where the revenue life cycle is short and decreasing with any time-to-market delay. The SLTI-NPD project management decision is to assign …

Inter-Relationship Of Mechanical And Bio-Chemical Processes Governing The Settlement Of Municipal Solid Waste (Msw) Using The (C +H)/L Ratio, Joseph John Lifrieri

Dissertations

This research discusses the results of experimentation that determines the rates and magnitudes of consolidation and settlement of solid waste materials dependent upon their actual state of biodegradation decomposition and time in place. The state of decomposition of waste is determined by measuring its cellulose plus hemicellulose to lignin ratio ((C + H)/L). The samples were collected from bioreactors, at consecutive time intervals, to simulate states of decomposition.

Each sample was tested in consolidation to determine the value of the primary compression index C' _c, the secondary compression index "the inorganic creep rate" coefficient, C' _α, and the …

End-Of-Life Analysis Of Nanotechnology Products, Sun Olapiriyakul

Dissertations

Previous research has shown that thermodynamic properties including melting point and specific heat capacity of nanomaterials may be higher than that of their corresponding bulk materials. The melting point elevation and specific heat capacity enhancement of nanomaterials may result in increased energy consumption and waste gases emission at the end-of-life (EOL) stage where the products containing nanomaterials are recycled by high temperature metal recovery (HTMR) process.

In this dissertation, the effect of physical characteristics of nanomaterials, referred to as physicochemical parameters, on their melting temperature and specific heat capacity was investigated. In addition, physical, chemical, and thermodynamic properties of nanomaterials …

Cooperative Retransmission Protocols In Fading Channels : Issues, Solutions And Applications, Igor Stanojev

Dissertations

Future wireless systems are expected to extensively rely on cooperation between terminals, mimicking MIMO scenarios when terminal dimensions limit implementation of multiple antenna technology. On this line, cooperative retransmission protocols are considered as particularly promising technology due to their opportunistic and flexible exploitation of both spatial and time diversity. In this dissertation, some of the major issues that hinder the practical implementation of this technology are identified and pertaining solutions are proposed and analyzed. Potentials of cooperative and cooperative retransmission protocols for a practical implementation of dynamic spectrum access paradigm are also recognized and investigated. Detailed contributions follow.

While conventionally …

Optimal Synthesis Of Planar Adjustable Mechanisms, Chong Peng

Dissertations

Adjustable mechanisms provide degrees of flexibility while retaining desirable features of one degree of freedom close-loop mechanisms, such as simplicity, stability, and high speed capabilities. By adjusting linkage parameters, additional phases of motions can be achieved using the same hardware. However, an adjustment to the mechanism adds only one or two additional design positions and divides desired positions into "phases", each of which contains only a few positions usually insufficient for industrial applications.

In order to extend the design position limitation of adjustable mechanisms, an optimal synthesis method based on link length structural error is developed and applied to kinematic …

Soft-Error Resilient On-Chip Memory Structures, Shuai Wang

Dissertations

Soft errors induced by energetic particle strikes in on-chip memory structures, such as L1 data/instruction caches and register files, have become an increasing challenge in designing new generation reliable microprocessors. Due to their transient/random nature, soft errors cannot be captured by traditional verification and testing process due to the irrelevancy to the correctness of the logic. This dissertation is thus focusing on the reliability characterization and cost-effective reliable design of on-chip memories against soft errors.

Due to various performance, area/size, and energy constraints in various target systems, many existing unoptimized protection schemes on cache memories may eventually prove significantly inadequate …

Adaptive Trust And Reputation System As A Security Service In Group Communications, Pitipatana Sakarindr

Dissertations

Group communications has been facilitating many emerging applications which require packet delivery from one or more sender(s) to multiple receivers. Owing to the multicasting and broadcasting nature, group communications are susceptible to various kinds of attacks. Though a number of proposals have been reported to secure group communications, provisioning security in group communications remains a critical and challenging issue.

This work first presents a survey on recent advances in security requirements and services in group communications in wireless and wired networks, and discusses challenges in designing secure group communications in these networks. Effective security services to secure group communications are …

Synthesis And Characterization Of Metal Oxide Semiconductors For Photoelectrochemical Hydrogen Production, Sudhakar Shet

Dissertations

The goal of this thesis is to investigate the properties of metal-oxide thin films on fluorine-doped tin oxide (FTO)-coated glass substrates, prepared by using radio- frequency (RF) reactive magnetron sputtering for photoelectrochemical (PEC) applications. Metal-oxide thin films as a photoelectrode are of special interest for PEC systems to produce hydrogen in an aqueous solution by solar energy due to their low cost and potential stability.

The following list represents some of the accomplishments and results of this work:

• Narrowing of N-incorporated ZnO (ZnO:N) was achieved by reactive sputtering in a O₂/N₂ mixture ambient, and ZnO:N films with …

Generalized Discrete Fourier Transform With Non-Linear Phase : Theory And Design, Handan Agirman-Tosun

Dissertations

Constant modulus transforms like discrete Fourier transform (DFT), Walsh transform, and Gold codes have been successfully used over several decades in various engineering applications, including discrete multi-tone (DMT), orthogonal frequency division multiplexing (OFDM) and code division multiple access (CDMA) communications systems. Among these popular transforms, DFT is a linear phase transform and widely used in multicarrier communications due to its performance and fast algorithms. In this thesis, a theoretical framework for Generalized DFT (GDFT) with nonlinear phase exploiting the phase space is developed. It is shown that GDFT offers sizable correlation improvements over DFT, Walsh, and Gold codes. Brute force …

Motion Coordination And Control In The Development Of A Gait Rehabilitation System, Yazan Ahmad Manna

Dissertations

While most take their ability to walk for granted, some are unable to walk due to any number of pathologies, such as traumatic brain injury (TBI), spinal cord injury (SCI), and Parkinson's disease. Decreased activity has been shown to be associated with rapidly deconditioning. Rehabilitation techniques that afford patients the ability to begin reconditioning through walking sooner may ultimately enhance their return to a better quality of life. To assist the functional recovery of such patients, an appropriate afferent input to the spinal cord will help in the therapy of the patient. Manual training is labor intensive, costly, and ergonomically …

Advanced Classification Of Ofdm And Mimo Signals With Enhanced Second Order Cyclostationarity Detection, Miao Shi

Dissertations

With the emergence of cognitive radio and the introduction of new modulation techniques such as OFDM and MIMO, the problem of Modulation Classification (MC) becomes more challenging and complicated. In the first part of the thesis, we explore the automatic modulation classification to blindly distinguish OFDM from single carrier signals. We use the fourth order cumulants; an approach which in the past has been also applied to classify single carrier signals. A blind OFDM parameter estimation scheme was then followed, which includes the estimation of number of subcarriers, CP length, timing and frequency offset and the oversampling factor for the …