Engineering Commons^™

Trust Management Schemes For Peer-To-Peer Networks, Lin Cai

Dissertations

Peer-to-peer (P2P) networking enables users with similar interests to exchange, or obtain files. This network model has been proven popular to exchange music, pictures, or software applications. These files are saved, and most likely executed, at the downloading host. At the expense of this mechanism, worms, viruses, and malware find an open front door to the downloading host and gives them a convenient environment for successful proliferation throughout the network. Although virus detection software is currently available, this countermeasure works in a reactive fashion, and in most times, in an isolated manner. A trust management scheme is considered to contain …

Hot-Melt Mixing Of Partially Miscible Active Pharmaceutical Ingredient-Polymer Mixtures, Min Yang

Dissertations

Solid dispersion/solution processes for producing pharmaceutical oral dosages such as hot-met extrusion (HME) have received increasing attention by industry and academe because they can enhance drugs’ solubility and even bioavailability to a great extent by converting drugs from crystalline to amorphous form. HME can be carried out at two process temperature regimes: one where T_process > T_m of the drug and the T_g of the polymer (or the T_m for the case of semi-crystalline polymers); the other at T_m > T_process > T_g (T_m for the case of semi-crystalline polymer). Processing below the drug’s …

Micromechanical Study Of Two-Phase Flow During Air Sparging, Shengyan Gao

Dissertations

Air sparging (AS) is an in-situ soil/groundwater remediation technology, which involves the injection of pressurized air/oxygen through an air sparging well below the region of contamination. The efficiency of the in-situ sparging system is mainly controlled by the extent of contact between injected air and contaminated soil and pore fluid. Hence, characterizing the mechanisms governing movement of air through saturated porous media is therefore critical to the design of an effective cleanup treatment. However, in spite of the success of air sparging as a remediation technique for the clean-up of contaminated soils, to date, the fundamental mechanisms or the physics …

Development Of X-Ray Holography Methods For Structure Determination : Application Of High Speed Detectors And Novel Numerical Methods, Yuhao Wang

Dissertations

Holographic methods show much promise to enable direct determination of atomic structure with minimal assumptions and approximations. The approach can, in principle, provide three dimensional information on atomic positions. However, significant developments in experimental techniques, instrumentation and in data collection and analysis are needed. A review of the holography method is given with a focus on X-ray fluorescence holography. Methods for analysis of X-ray holographic data are also reviewed. An overview of the detectors relevant to X-ray measurements is also presented. An experimental apparatus for rapid acquisition of X-ray holographs using novel X-ray detectors has been developed. The integration of …

Distributed Spectrum Leasing Via Cooperation, Tariq Elkourdi

Dissertations

“Cognitive radio” networks enable the coexistence of primary (licensed) and secondary (unlicensed) terminals. Conventional frameworks, namely commons and property-rights models, while being promising in certain aspects, appear to have significant drawbacks for implementation of large-scale distributed cognitive radio networks, due to the technological and theoretical limits on the ability of secondary activity to perform effective spectrum sensing and on the stringent constraints on protocols and architectures.

To address the problems highlighted above, the framework of distributed spectrum leasing via cross-layer cooperation (DiSC) has been recently proposed as a basic mechanism to guide the design of decentralized cognitive radio networks. According …

Hydrogen Storage In Pt/Carbon Nanotube Sheets, An-Yu Ma

Theses

Three types of self-assembled carbon nanotube (CNT) sheets, for example, carboxylic functionalized multi-walled CNTs (MWNTs-COOH), pure multi-walled CNTs (MWNTs), and pure single-walled CNTs (SWNTs), were prepared as substrates by ambient environment vacuum filtration of suspensions of the nanotubes. To enhance hydrogen storage on the CNTs, platinum particles were deposited on the three types of CNT sheets using two processes: electrodeposition (ED) using a DC power source and electrochemical deposition under cyclic voltammetry (CV). To verify platinum deposition on the surface of the CNT sheets, a Scanning Electron Microscope (SEM) was used to obtain images, and Energy Dispersive X-ray (EDX) spectroscopy …

Preparation Of Different Polyamide Nanofiltration Membranes By Interfacial Polymerization And The Effect Of Post-Polymerization Treatment On Separation Performance, Yu Qin

Theses

Interfacial polymerization (IP) is a powerful technique for fabrication of thin film composite (TFC) membranes. In this study, polyamide nanofiltration (NF) composite membranes ware prepared by interfacial polymerization of polyethylenimine (PEI) or m-phenylene diamine (MPD) with isophthaloyl dichloride (IPD) on the surface of a porous polyethersulfone (PES) support. Concentrations of monomer reactants for this reaction were decided by equivalent weight ratio. A standard IP procedure was applied to successfully coat PES flat films. After preparation, three different post-polymerization treatments were employed and one optimal treatment was proven after membrane testing.

The TFC flat film membranes were characterized by nanofiltration of …

Neuralsta: A Software Tool For Neural Stimulation And Recording Applications With A Laser Control, Rimi Sahu

Theses

The subject of this thesis is a software tool created in Matlab ® for neural stimulation and recording of the evoked potentials. The stimulation output can be delivered in electrical units for immediate use for neural stimulation or as a power control signal to a laser. NeuralSTA is designed to generate arbitrary waveforms of stimulation and simultaneously record the neural response while implementing the spike triggered averaging (STA) method, hence the name NeuralSTA. The output (stimulation) signal can be created in monophasic, biphasic or inverted monophasic forms (for laser control applications). Controls for pulse modulation allow shaping of the pulse …

The Mechanical Testing Of Single Nanofiber, Pratik Manohar Dahule

Theses

Polymer nanofibers exhibit properties that make them a favorable material for the development of tissue engineering scaffolds, filtration devices, sensors, and high strength lightweight materials. Perfectly aligned PLLA Nanofibers were fabricated by an electrospinning technique under optimum conditions and the diameter of the electrospun fibers can easily be tailored by adjusting the concentration of the polymer solution. To align the nanofibers, special arrangement was made in terms of two aluminum plates. Good alignment of polymer nanofibers on specimen was confirmed by SEM observation. The effect of different electro-spinning parameters on maximum fiber length, average fiber diameter, diameter uniformity, and fiber …

Combustion Dynamics Of Individual Reactive Material Particles, Carlo Francisco Badiola

Theses

Metallic reactive powders are widely used as solid fuels, pyrotechnic materials, and components of enhanced blast explosives. Metals are attractive because of their high combustion enthalpies and temperatures. Quantitative descriptions of the combustion processes and mechanisms for both pure metal and composite particles are also desired for their proper implementation in specific applications. Among reactive metals, Al is used most widely and its combustion has been studied extensively. A recently developed experimental setup using laser-ignited metal powders enabled one to record optical signatures for time-resolved combustion instances for 2-25 µm diameter aluminum particles burning in different atmospheres. Individual particle diameters …

Neural Differentiation Of Pluripotent Stem Cells And Applications To Micropatterned Agarose Hydrogel For Nerve Guidance, Jamila S. Gittens

Theses

Many central nervous system (CNS) disorders are attributable to damaged oligodendrocytes, the cells that form the myelin sheath of axons. An effective source of human oligodendrocytes is crucial, making pluripotent stem cells, such as embryonic stem (ES) cells, an attractive source for nerve tissue repair and regeneration due to their unlimited capacity for self-renewal and their ability to differentiate into all major cell lineages. Bioengineered 3-D hydrogel culture systems have the potential to elucidate mechanisms required for regeneration of CNS cells. The goals of this study are: (1) to investigate the effects of retinoic acid (RA), sonic hedgehog (shh) agonist, …

Development Of 3-D Liver Model For Drug Screening Applications, Divya Rajendran

Theses

The need for a an in vitro drug screening system that mimics the structural organization of natural liver for multi-functionality and maintenance of hepatocytes has become vital in the drug development process. The objective of this study was to engineer a three-dimensional (3-D) liver model using chitosan-based nanofiber scaffolds and co-culture system (adult rat hepatocytes and 3T3-J2 fibroblasts) to mimic the natural liver and to justify its application for in vitro drug screening. Chitosan nanofiber scaffolds were fabricated by electrospinning technique. In order to promote cell adhesion on the chitosan scaffolds, the scaffolds were coated with a cell adhesion molecule, …

Development Of Gis Database For Hayward Fault, Olugbope Maku

Theses

Earthquake activity and its attendant effects on the earth surface have been a major concern for some time now, especially considering their negative effects in loss of human life, property damage including the emotional impact on witnesses. This study focuses on the Hayward Fault, located in the heart of population center in Contra Costa County of the San Francisco Bay Area, California.

Geographical Information System (GIS) has proved to be a valuable tool in recent years in the study and analysis of earthquakes to complement emergency response efforts. GIS has been adapted to estimate the impact of the geologic hazards …

Temperature Elevations Due To Nir Exposure In The Brain Tissue, Ali Ersen

Theses

Near infrared (NIR) lasers have been used in medical applications both for diagnostic and therapeutic purposes. Temperature elevation profile inside the tissue is a critical factor that needs to be better understood in these applications. The purpose of this study is to determine the temperature distribution due to a low power N I R laser irradiation in living neural tissue. Temperature measurements were made directly using a thermocouple probe inside the rat brain cortex within the sagittal plane. The spatial map indicates that N I R light penetrates more readily in the vertical directions than the spreading in the horizontal …

Single-Carrier Frequency Domain Equalization Using Subband Decomposition For Optical Wireless Communications, Di Mu

Theses

Optical wireless communication is intended to be applied into indoor and visual distance high-rate data transmission, which is complementary to radio frequency communications. There are specific problems and requirements in optical wireless communications compared with radio frequency communications. Single-carrier frequency domain equalization (SCFDE) is a transmission scheme which has been considered as an alternative of orthogonal frequency-division multiplexing (OFDM), because it has most of the advantages of OFDM and avoids the problems of OFDM. Subband decomposition is a multi-resolution signal analysis and synthesis method, using quadrature mirror filter (QMF) bank to convert time-domain signal to frequency-domain subbands. As a time-to-frequency …

Analysis And Mitigation Of Carrier Frequency Offset For Uplink Of Ofdma, Abhishek R. Panchal

Theses

Orthogonal Frequency Division Multiplexing (OFDM) is being used in many wireless standards because of its immunity to multipath fading, high spectral efficiency and simple implementation, making it suitable for high data rate multimedia wireless applications. One of the significant drawbacks of the OFDM is its sensitivity to Carrier Frequency Offset (CFO). CFO causes Inter Carrier Interference (ICI) between subcarriers and Multiple User Interference (MUI) at Uplink between different users. ICI and MUI at uplink cause significant degradation in the performance of the receiver, therefore, to improve the receiver performance up to acceptable level, compensation of the CFO becomes necessary.

In …

Soy Protein-Poly (L-Lactic Acid) Blend Nanofibers For Drug Delivery Of Nardostachys Jatamansi, Swetha Tiwari

Theses

Electrospun nanofibers when nanofi bers are impregnated with drugs play a significant role in drug delivery. Nanomedical approaches to drug delivery focus on developing nanoscale particles or molecules to improve the bioavailab ility of a drug.

Biodegradable nanofibers were developed using Poly (L – lactic acid) and Soy protein for the delivery of an ayurvedic drug, Nardostachys jatamansi. A weighed quantity of powdered drug – Nardostachys Jatamansi was subjected to Soxhlet extraction using water and ethanol in equal quantities. Various blends of the drug extract and soy protein solution are prepared and mixed in Poly (L-lactic acid). Nanofibers of …

Dynamic Friction: Measurement And Results, Yanal Jij

Theses

Friction has been known as a phenomenon since Leonardo da Vinci era. From that time and through the last four centuries, scientists tried to understand this phenomenon in an effort to overcome its undesired side effects which include energy loss, parts wearing, and errors in control systems. Much has been achieved in studying friction and many experiments have been conducted in this field. These experiments resulted in a mounting evidence that friction is a dynamic phenomenon.

This thesis presents an apparatus that measures dynamic friction in linear motion and the results obtained using this apparatus. The apparatus consists of a …

Alendronate Treatment Elicits A Reduction In Fatigue-Life Of Canine Cortical Bone, Joseph Ryan Geissler

Theses

Bone serves contradictory needs; bone must be strong yet light, and stiff yet flexible. At the tissue level bone material withstands cyclic loading without failing by dissipating energy via the formation and accumulation of microdamage. Proper removal of this damage in exchange for fresh tissue is vital to bone maintenance, and is achieved through a remodeling process. Imbalanced remodeling leads to osteoporotic fractures. Bisphosphonate drugs are proven to reduce fracture risk. However, the long-term effects of bisphosphonates on tissue-level properties are unknown. This study characterized the fatigue-life of cortical bone tissue after bisphosphonate treatment with alendronate (Aln). 1 1th ribs …

A New Method For Node Ranking For Voltage Stability In Power Systems, Hongxiang Li

Theses

The voltage collapse in power system is a major concern for reliable operation of these systems. In this thesis, a method is proposed to determine the load margins at load nodes (loadability limits). A good portion of the computation to obtain those margins is routinely done when solving the power flow problem, thus the computational effort is greatly reduced. The proposed method is based on the fact that when voltage collapse occurs the Jacobian matrix, that is calculated when performing power flow analysis, is singular. The relationships between the elements of the Jacobian matrix and the nodal powers are exploited …

Theoretical Prediction Of Joint Reaction Force In A Dynamic General 3-D Pendulum Tree Model For Human Or Animal Motion, Sucheta Goyal

Theses

Lagrangian dynamics and the method of superfluous coordinates are applied to predict dynamic joint reaction forces in an idealized flexible model of a branched 3-D pendulum tree system. The number of segments and joints on the tree are adjustable as is the branching tree pattern. The segments that comprise the tree are assumed to be one- dimensional rigid rods containing a discrete set of mass points that is both flexible in number and distribution on the tree. The idealized 3-D pendulum tree system is intended to provide a flexible theoretical framework to model and better understand the dynamics of human …

Theoretical Prediction Of Drug Release In Gi Tract From Spherical Matrix Systems, Naga Lakshmi Ramana Susarla

Dissertations

The significance of controlled release drug delivery systems (CRDDS) lies in their ability to deliver the drug at a steady rate thus reducing the dosage interval and providing a prolonged pharmacodynamic effect. But despite the steadily increasing practical importance of these devices, little is known regarding their underlying drug release mechanisms. Mathematical modeling of these drug delivery systems could help us understand the underlying mass transport mechanisms involved in the control of drug release. Mathematical modeling also plays an important role in providing us with valuable information such as the amount of drug released during a certain period of time …

Dispersion Of Particles On Liquid Surfaces, Sathishkumar Gurupatham

Dissertations

When small particles (e.g., flour, pollen, etc.) come in contact with a liquid surface, they immediately disperse. The dispersion can occur so quickly that it appears explosive, especially for small particles on the surface of mobile liquids like water. This explosive dispersion is the consequence of capillary force pulling particles into the interface causing them to accelerate to a relatively large velocity. The maximum velocity increases with decreasing particle size; for nanometer-sized particles (e.g., viruses and proteins), the velocity on an air-water interface can be as large as 47 m/s. They also oscillate at a relatively high frequency about their …

The Impact Of Dynamic And Passive Standing On Bone Mineral Density And Appositional Growth In Immobilized Children, Megan Diane Damcott

Dissertations

The first discovery of the potential role that mechanical loading has on determining the strength of bone occurred in 1892. However, for almost a century after this discovery, the specific mechanisms influenced by mechanical loading remained locked in a mysterious 'black box'. Then in the 1960s, the 'black box' was opened and continued work has now unlocked the basic mechanisms involved in mechanical loading and whole-bone strength. This increased knowledge has spurred clinicians and researchers to investigate the impact of weight-bearing interventions on individuals with an increased risk of osteoporosis. The most common weight-bearing clinical intervention used in non-ambulant populations …

Effects Of Operating And Geometric Variables On Hydrodynamics And Tablet Dissolution In Standard And Modified Dissolution Testing Apparatuses 2, Yimin Wang

Dissertations

Dissolution testing is routinely conducted in the pharmaceutical industry to provide critical in vitro drug release information for quality control purposes, and especially to assess batch-to-batch consistency of solid oral dosage forms such as tablets. Among the different types of apparatuses listed in the United States Pharmacopoeia (USP), the most commonly used dissolution system for solid dosage forms is the USP Dissolution Testing Apparatus 2, consisting of an unbaffled, hemispherical-bottomed vessel equipped with a 2-blade radial impeller.

Despite its extensive use in industry and a large body of work, some key aspects of the hydrodynamics of Apparatus 2 have received …

Synthesis And Development Of Boron Nanotubes And Metal/Ceramic-Carbon Nanotube Composites, Jinwen Liu

Dissertations

The first part of this thesis will be focused on developing a facile and scalable solid — solid chemical vapor deposition (CVD) process using a solid boron precursor to synthesize crystalline boron nanotubes (BNTs) mixed with small amounts of boron nanofibers (BNFs). The synthesis involves the use of solid boron precursors - magnesium boride and magnesium borohydride, magnesium and nickel boride as co-catalysts, and porous MCM-41 zeolite as the growth template. Experimental parameters, such as temperature, grinding of constituents and starting precursor-catalyst-template compositions, were studied and optimized. Detailed characterization have been carried out using field-emission scanning electron microscopy (FE-SEM), transmission …

Multifunctional Reactive Nanocomposite Materials, Demitrios Stamatis

Dissertations

Many multifunctional nanocomposite materials have been developed for use in propellants, explosives, pyrotechnics, and reactive structures. These materials exhibit high reaction rates due to their developed reaction interfacial area. Two applications addressed in this work include nanocomposite powders prepared by arrested reactive milling (ARM) for burn rate modifiers and reactive structures. In burn rate modifiers, addition of reactive nanocomposite powders to aluminized propellants increases the burn rate of aluminum and thus the overall reaction rate of an energetic formulation. Replacing only a small fraction of aluminum by 8Al•MoO₃ and 2B•Ti nanocomposite powders enhances the reaction rate with little change …

Development Of A Vibration-Powered Impact Recorder, William Contreras

Theses

Currently, the U.S. Army stores a great deal of equipment for long periods of time. Often, this equipment is subjected to damaging vibrations. Given this, the army wants to be able to monitor the vibrations that are undergone by this equipment. Here, a battery-powered monitoring device would be undesirable because its batteries would need to be replaced. To solve this problem, an energy harvesting, vibration monitoring device has been developed. The device, which is known as a vibration-powered impact recorder (VPIR for short), uses a piezoelectric transducer to power a microcontroller, which uses the power to count the number of …

Influence Of Rear Wheel Tire Type On Wheelchair Propulsion Biomechanics, Mathew Yarossi

Theses

The objective of this study was to determine how rear wheel tire type affects wheelchair propulsion mechanics. Four persons with paraplegia and four persons with tetraplegia propelled their own wheelchairs on a roller system at self-selected speed using five different pairs of tires. Upper limb and trunk kinematics, perceived exertion, stroke pattern and the temporal characteristics of propulsion were measured. When using pneumatic (air filled) tires, with lower rolling resistance, participants had lower push frequency (p < .05), higher self selected speed (p < .05), less perceived exertion, less shoulder internal rotation, and a longer push stroke than when using solid, high rolling resistance tires. As rolling resistance increased, participants experienced negative changes in propulsion characteristic that contradicted current clinical practice guidelines for upper limb preservation following spinal cord injury. In addition, kinematics with solid, high rolling resistance tires were similar to those described during uphill or over carpet propulsion. In order to avoid unnecessary strain on the upper limbs and unwanted changes in propulsion biomechanics, wheelchair users, clinicians, and researchers should consider the use of lower rolling resistance, pneumatic rear tires.

Orthogonal Space Time Coding For Im/Dd Optical Wireless Communication With Single Carrier Frequency Domain Equalization, Nan Wu

Theses

Recently the development of optical wireless communication has received growing attention because of its unlimited bandwidth and simple implementation as compared to radio frequency communication application for indoor wireless data transmission. The objective of this thesis is to improve the performance of intensity-modulated direct- detection (IM/DD) optical wireless communications with single carrier frequency domain equalization (SCFDE) by using Orthogonal Space Time Code (OSTC). More attention has been paid to three SCFDE schemes due to their outstanding performances in practical cases. It is demonstrated that OSTC can be modified to be suitable to optical systems and provide an excellent enhancement to …