Engineering Commons^™

Optimization Of Ion-Exchange Chromotography With Multiple Gradient Inputs For Protein Separations, Tariq Mahmood

Theses

Gradient elution chromatography is an efficient technique for adjusting the retention of sample components during liquid chromatographic separations. However, the optimization of gradient elution is usually done by trial and error. Thus, for large scale processes this results in expensive and time consuming design and operations. Peak resolution that describes the degree of separation is a commonly used parameter for chromatographic processes. However, in processes where operating time and product dilution are of great importance, resolution alone is not adequate for describing the separation efficiency.

A new parameter "resolution optimization factor" is used for the optimization of gradient elution processes. …

Synthesis And Characterization Of Silicon Dioxide Thin Films By Low Pressure Chemical Vapor Deposition, Sutham Niyomwas

Theses

Ditertiarybutylsilane ( DTBS ) and oxygen have been used as precursors to produce silicon dioxide films by low pressure chemical vapor deposition. These films were synthesized in the temperature range of 600°C to 800°C at constant pressure, and at different gas flow composition. The films were found to be uniform with a composition that varied with deposition temperature and gas flow ratio. The growth rate was found to follow an Arrhenius behavior with an apparent activation energy of 2.62 kcal/mol. The growth rate was seen to increase with higher distance between wafers and to vary as a function of square …

Modeling Of Objects Using Planar Facets In Noisy Range Images, Girish Phansalkar

Theses

Products designed and manufactured before the advent of Computer Aided Design (CAD) and Computer Aided Manufacturing (CAM) technology have not been documented electronically. To avoid the laborious procedure of redesigning the parts, a reverse engineering approach can be adopted. This approach involves, taking a picture of the object and constructing a solid model from the image data.

Range image is a three dimensional image of an object or a scene. This image can be obtained from special cameras, called range image cameras, or can be constructed from the Coordinate Measuring Machine's (CMM) output data. Adaptive Fuzzy c-Elliptotype (AFC) clustering algorithm …

Experimental Study Of The Rise Of A Large Sphere In A Vibrated Bed Of Monodisperse Spheres, Loic Vanel

Theses

As a simplified way to study size segregation mechanisms, the rise of a single large sphere in a vibrated bed of smaller monodisperse spheres is investigated. The time it takes for the ball to rise from the bottom of the bed to the surface is measured in a very wide range of vibration amplitude, frequency and acceleration. Rise regimes are identified and are classified according to the macroscopic behaviors displayed by the granular bed: heaping, convection without heaping and crystallization. The influence of the large sphere's size on the rise velocity is described. The scaling features of the vibration amplitude …

Tcp/Ip Traffic Over Atm Network With Abr Flow And Congestion Control, Liping An

Theses

Most traffics over the existing ATM network are generated by applications running over TCP/IP protocol stack. In the near future, the success of ATM technology will depend largely on how well it supports the huge legacy of existing TCP/IP applications.

In this thesis, we study and compare the performance of TCP/IP traffic running on different rate based ABR flow control algorithms such as EFCI, ERICA and FMMRA by extensive simulations. Infinite source-end traffic behavior is chosen to represent, FTP application running on TCP/IP. Background VBR traffic with different ON-OFF frequency is introduced to produce transient network states as well as …

A Student Training Manual For Running The Hysim Computer Simulation Program, Roberta Rosty

Theses

Hyprotech's HYSIM computer simulation program is used in the chemical processing industry (CPI) to simulate unit operations, which aid in the design of various different kinds of processing plants. It is important then that chemical engineering students should gain early exposure to a simulation program such as HYSIM, in order to facilitate their comprehension of process engineering design work using this type of program, and to bridge the gap between the textbook knowledge they gain of unit operations in the classroom with some of the actual process engineering work-a-day methods available for solving problems.

The objective of this work was …

Microporous Silicon Dioxide/Vycor Membranes For Gas Separation, Justin R. Barone

Theses

This study focused on producing membranes for molecular sieving of gases by reducing the pore size of an already existing membrane structure. To do this, SiO₂ was deposited inside the pores of a Vycor tube with initial pore diameter of 4 nm. The film deposition took place by a low pressure chemical vapor deposition (LPCVD) process where diethylsilane (DES) and nitrous oxide (N₂O) were used as precursor gases. A counterflow reactant geometry was used where the precursor gases were flowed on both sides of the porous membrane. This deposition geometry gave higher selectivities and better mechanical stability. …

Trifluoroiodomethane As An Environmentally Friendly Gas For Water Patterning By Plasma Etching Process, Krit Aryusook

Theses

Trifluoroiodomethane (CF₃I), a non-global warming gas, has been investigated with study as a substitute for typical CFC etchants, such as CF₄ and C₂F₆, used in wafer pattering technology. This investigation was carried out by exposing dielectric films of silicon oxide (SiO₂) and silicon nitride (Si₃N₄) in CF₃I and C₂F₆/O₂ (used as a reference) plasma environments. The etch rate of these films was ascertained as function of applied rf power, etchant gas flow rate, reaction chamber operating pressure, and O_{2 …}

Design Of A Mode Of Delivery For Macrobead Transplantation, Jagdip Desai

Theses

The macrobead is a form of a biohybrid artificial pancreas (BAP), which is being developed to treat type 1 diabetes. A hypothetical human transplant would require 125 rat equivalent macrobeads. For intraperitoneal transplantation a mode of delivery that allows the placement of several hundred macrobeads into a basket or pouch type device is required.

In this study, four commercially available materials were studied as possible candidates for creating a pouch. These materials are polyvinyl chloride acrylic copolymer (PVC), polyethersulfone (PES), polyvinylidenedifluoride (PVDF), and polytetrafluorethylene (PTFE). Tubular pouches of each material were designed. They then underwent in vivo biocompatibility and in-vitro …

Vibration Control Of Robotic Modules Using Input Shaping Algorithm, Murat Eren

Theses

In this thesis, vibration control using input shaping algorithm is studied. Vibration Control of flexible structures is an important problem and has been an active research area. Different approaches have been developed for vibration control which can be divided roughly into feedback and feedforward methods. Feedback methods need measurements and on-line calculation of the controller outputs. Although feedback methods are generally more robust and have a number of well known performance advantages, proper use of feedforward control can also significantly improve the speed of response of the system.

Input shaping is one of these feedforward methods. It has been successfully …

Design, Simulation And Fabrication Of A Mems In-Situ Contactless Sensor To Detect Plasma Induced Damage During Reactive Ion Etching, Subramanian Ganesh

Theses

The present trend in the semiconductor industry is towards submicron devices. An inevitable process technique in achieving this is by reactive ion etching of the polysilicon gate. During RIE, the gate oxide may get damaged due to several causes. One of the main causes of the damage is the non-uniformity of the plasma. It is reported that these plasma inconsistencies are mainly due to electrode design and that they create spatial plasma potential fluctuation. These fluctuations are reported to be in the range of 10-20 Volts. By providing an in-situ monitoring of the wafers, the reliability of the device could …

Experimental Investigation Of Collisional Properties Of Spheres, Laurent Labous

Theses

We present experimental results on the collisional properties of spheres obtained through high-speed video analysis. An apparatus is built that produces collisions of spheres of various sizes with a wide range of impact, velocities and incidence angles.

Edge detection techniques are implemented to track the position of the spheres from frame to frame whereby the translational velocities may be computed. In order to determine the rotational velocities, small markers are imprinted on the surfaces of the spheres and also tracked and matched from one frame to the next.. From the pre and post collision kinematic data, three collisional properties are …

Synthesis And Characterization Of Hafnium Carbide Thin Films, Wiriya Thongruang

Theses

Hafnium carbide thin films of various characteristics were deposited on silicon substrates using dc magnetron sputtering. A HfC target was used as a sputtering source and Ar was used as a sputtering gas during deposition. The variables investigated were total sputtering gas pressure and power. Optimum characteristics were achieved with a total sputtering gas pressure of 5 mTorr and power of 200 W. No evidence for oxidation of the film was found at a depth below 400A for deposited and annealed films. Binding characteristics were obtained from ESCA data. The compressive film stress increased when sputtering gas pressure decreased. The …

Relaxation And The Nature Of Electrical Stress Related Defects In Ultra-Thin Dioxide On Silicon, Lihui Xie

Theses

The instability of defects created in ultra-thin insulator, metal-oxide-silicon devices biased in the direct tunnel regime is investigated. For the case of electron injection from the silicon substrate, nearly complete defect relaxation is observed after the bias is removed, allowing the possibility of re-generating the defects. Modeling the defect generation process and examining differences between initial and subsequent degradation periods lead to an improved picture of both the relaxation process and the nature of the involved defects.

Performance Evaluation Of Cebus Power Line Communication In The Presence Of X-10 Module Signaling, Nashwa F. Kamel

Theses

A power line of CEBus has great potential towards inexpensive home automation. Both PLBus and X-10 uses [sic] burst of 120KHz signals to transmit bits of information on the power line. However, these two systems are completely incompatible and can conflict with each other. This thesis presents the first performance evaluation of Power Line CEBus communication in the presence of X-10 module signaling. The evaluation included simulation experiments measuring packet delays, message delays, message throughput, channel throughput and the percentage of messages received in error verses [sic] different loads. Network performance has been confirmed to function well in terms of …

Measuring The Need For Manufacturing Flexibility And Evaluating Its Economic Benefits, Navin Karwande

Theses

Flexible systems are known of enabling organizations to take advantage of diversified products, low volume production items with short life-cycles. They also improve the ability to respond to market changes. Flexibility has thus become a strategic manufacturing need in recent years.

Because of the high initial capital outlay involved, the selection of the appropriate flexible solution has become a critical issue. This thesis proposes a methodology to determine the most cost effective and feasible flexibility strategy. A flexibility audit is developed to analyze and evaluate the changes taking place in a facility's environment. These changes and a measurement scheme is …

A Methodology For The Design Of An Integrated Air Stripping/Biofiltration Process To Clean Contaminated Aquifers, Pothitos Ioannis Stamatiadis

Theses

This thesis deals with the conceptual design of an integrated air stripping/biofiltration process for cleaning aquifers contaminated with volatile organic pollutants. In this technology, the pollutant is transferred from the aquifer to an air stream which is subsequently treated in a biofilter. The work presented here is an effort to develop a design methodology for the integrated process and suggests a general, quantitative approach which can be used in preliminary technology evaluation. This methodology involves relatively simple equations for the stripping process and detailed (oftentimes complex) models for biofiltration under conditions of continuous variation of the properties of the polluted …

Fracture Mechanics Of High Strength Concrete Members, Rajendra K. Navalurkar

Dissertations

This study investigates the behavior of High Strength Concrete (HSC) under uniaxial state of stresses. Emphasis is placed on experimental evaluation of important mechanical and fracture properties. Owing to high brittleness of HSC, experimental results especially on tensile behavior have been largely limited and scarce. In this research, direct uniaxial tension tests are employed for determination of the post-peak tensile softening characteristics of HSC. The softening characteristics of high strength concrete is found to be considerably different than that of normal strength concrete (NSC). Fracture energies evaluated form the descending branch of the stress softening reveal significant drop in the …

A Controlled Release Technique Using Microporous Membranes, Stephanie Farrell

Dissertations

A novel controlled release device based on aqueous-organic partitioning is described. The device comprises a reservoir, bounded by a microporous or porous membrane in the form of a hollow fiber or flat film. The reservoir liquid phase and the pore liquid phase are immiscible. The agent partitions between the phases at the aqueous-organic interface of the reservoir and the pore mouth, and then diffuses through the membrane pore liquid into a surrounding aqueous solution. The partition coefficient significantly influences the rate of release of the agent by reducing the driving force for diffusion across the fluid-filled membrane pore. The performance …

Vapor-Liquid Phase Equilibria Of Nonideal Fluids With A Ge-Eos Model, Socrates Ioannidis

Dissertations

This study dealt with the prediction and correlation of vapor-liquid equilibria behavior of nonideal fluids. The thermodynamic formalism of the G^E-EoS models, which combines the two traditional methods γ-Φ and Φ-Φ used so far for low and high pressure phase equilibria correlations respectively, has been combined with the 1FG^E model, based on one-fluid theory, to produce a more consistent approach to the phase equilibrium problem.

In the first part of our study we examine the predictive abilities of our model for vapor-liquid equilibria of highly nonideal fluids. The results establish the fact that the Huron-Vidal mixing rule …

Local Stresses On Lateral Pipe-Nozzle With 45 Degree Angle Intersection, James Jin Xu

Dissertations

This dissertation presents a comprehensive study of local stresses, due to internal pressure around a pipe-nozzle with 45 degree angle intersection_ The resulting circumferential and longitudinal stresses on the pipe around the pipe-nozzle region are normalized as local stress factors and plotted as function of beta, β, (the radius of the nozzle/the radius of the pipe) and gamma, y, (the radius of the pipe/the thickness of the pipe) through the finite element method. The range of beta, [3, is from 0.1, to 1.0, and gamma, y, from 10 to 300. Comprehensive studies were made for the boundary parameters, such as …

Motion Estimation And Video Coding, Xiaochun Xia

Dissertations

Over the last ten years. research on the analysis of visual motion has come to play a key role in the fields of data compression for visual communication as well as computer vision. Enormous efforts have been made on the design of various motion estimation algorithms.

One of the fundamental tasks in motion estimation is the accurate measurement of 2-D dense motion fields. For this purpose. we devise and present in this dissertation a multiattribute feedback computational framework. In this framework for each pixel in an image. instead of a single image intensity. multiple image attributes are computed as conservation …

Scheduling And Discrete Event Control Of Flexible Manufacturing Systems Based On Petri Nets, Huanxin Henry Xiong

Dissertations

A flexible manufacturing system (FMS) is a computerized production system that can simultaneously manufacture multiple types of products using various resources such as robots and multi-purpose machines. The central problems associated with design of flexible manufacturing systems are related to process planning, scheduling, coordination control, and monitoring. Many methods exist for scheduling and control of flexible manufacturing systems, although very few methods have addressed the complexity of whole FMS operations. This thesis presents a Petri net based method for deadlock-free scheduling and discrete event control of flexible manufacturing systems. A significant advantage of Petri net based methods is their powerful …

Removal Of Volatile Organic Compounds From Contaminated Groundwater By Pervaporation, Sukla Chandra

Theses

Effective removal of non-aqueous phase liquid pools in groundwater and volatile organic compounds (VOCs) from contaminated soils can be achieved by surfactant flushing. This surfactant-rich ground water contains VOCs like trichloroethylene (TCE), dichloroethylene (DCE), etc. Membrane pervaporation technique is employed here to remove TCE from these micellar systems where a very high percentage of the VOC is trapped inside the micellar core. The micellar solution flows through the bore of microporous hydrophobic hollow fibers wherein the micelles break down and release the surfactants and the TCE. The TCE is then removed through the pores and a nonporous thin silicone skin …

Biodegradation And Landfill Settlement, Shailesh Pisolkar

Theses

The most widely used method for the final disposal of solid waste is landfilling, which is also economical and simpler than most other disposal systems. Long term settlement in a landfill occurs mainly due to biodegradation of the refuse which is a very slow microbiological process. However, if the rate of biodegradation is enhanced, it may be possible to achieve early stabilization, faster settlement, consequently more capacity of the landfill to handle waste.

The objective of this research is to study the effects of enhanced biodegradation on settlement and to compare these results to other models used for predicting landfill …

Solids Suspension And Power Dissipation In Stirred Tanks Agitated By An Impeller Near The Tank Bottom, Ernesto Uehara-Nagamine

Theses

In this work, the effect of very small impeller clearances off the tank bottom, C, on complete solid off-bottom suspension, Njs, was investigated. Four types of impellers were used six-blade flat-disk turbine, six-blade flat-blade turbine, six-blade flat (45 degreees) pitched-blade turbine, and the high efficiency impeller Chemineer HE-3. The effects of the impeller diameter, D, tank diameter, T, and solids loading, X, were quantified. The presence of two impellers was analyzed using impellers of the same type and size.

Typically, Njs and the power consumption were found to decrease with the impeller clearance. However, for lower C/T values, a slight …

Modeling Of Cardiovascular System To Simulate Ventricular Septal Defect, Adarsh Kumar Gupta

Theses

The hemodynamics of the ventricular septa] defect is studied using a mathematical modeling technique. A twelve-compartment windkessel model of cardiovascular system is used to study the hemodynamics of the ventricular septal defect. The VSD is incorporated into the model via a parallel flow from the left to right ventricles (left-to-right shunt). The resistance to flow through the shunt is used to characterize the severity of the defect. Changes in the severity of the shunt flow produces changes in the ratio of pulmonary to systemic flow in the circulation. When the pulmonary to systemic flow ratio is more than 2:1, the …

The In Vitro Evaluation Of Various Biodegradable Composites Used In Internal Fixation Devices, Hui-Chen Hsieh

Theses

In vitro degradation kinetics and mechanical properties of various composites, comprising a polycarbonate (DTE polymer) reinforced with CaP glass fiber, synthetic ceramic and non-ceramic hydroxyapatite (HA-500,OsteoGen HA) were investigated.

They were soaked in the SBF solution with a constant pH of 7.4 at 37°C for 5 days. The DTE/CaP composite degraded in an acid manner such that a large amount of NaOH was required but with a small decrease in calcium ion concentration. By contrast, the DTE/OsteoGen HA composite required comparable amounts of NaOH, but with a concomitantly large decrease in calcium ion concentration. This showed that the OsteoGen HA …

Effect Of Lamellar Microstructure On The Permeability Of Polyethylene Films, Yufu Li

Theses

Lamellar microstructures can decrease the permeability to gases and vapors by increasing the diffusive path in plastic films, or the so-called "tortuosity" which depends on the aspect ratio, orientation, and the volume fraction of the dispersed material. In this research, different types and percentages of mica with relatively high aspect ratio are used as oxygen barrier materials in blown films. Both high and low density polyethylenes (HDPE and LDPE), as well as their blends are used as the matrix materials.

A decrease in permeability of both LDPE and HDPE films to oxygen is achieved with increasing volume fraction of the …

Fabrication Of Integrated Optic Sensor To Monitor Pollutant Concentration In Effluents, Kiran Chatty

Theses

An attempt has been made to fabricate an integrated optic sensor to monitor pollutant concentration in effluents. Optic fiber has to be coupled to the waveguide in order to send light through the waveguide. In order to facilitate the easy coupling of the fiber to the waveguide, V-grooves were formed in the silicon substrate. In order to achieve this Silicon nitride was deposited to serve as an etch mask. An attempt was made to obtain low stress silicon nitride films.

This work also attempted to synthesize the materials required to fabricate the waveguide. LPCVD processes were developed to produce undoped …