Engineering Commons^™

Pre- And Post-Alpha Motoneuronal Control Of The Soleus H-Reflex During Sinusoidal Hip Movements In Human Spinal Cord Injury, Maria Knikou, Debjani Chaudhuri, Elizabeth Kay, Brian D. Schmit

Biomedical Engineering Faculty Research and Publications

The aim of this study was to establish the contribution of hip-mediated sensory feedback to spinal interneuronal circuits during dynamic conditions in people with incomplete spinal cord injury (SCI). Specifically, we investigated the effects of synergistic and antagonistic group I afferents on the soleus H-reflex during imposed sinusoidal hip movements. The soleus H-reflex was conditioned by stimulating the common peroneal nerve (CPN) at short (2, 3, and 4 ms) and long (80, 100, and 120 ms) conditioning test (C-T) intervals to assess the reciprocal and pre-synaptic inhibition of the soleus H-reflex, respectively. The soleus H-reflex was also conditioned by medial …

99mTc-Labeled C2a Domain Of Synaptotagmin I As A Target-Specific Molecular Probe For Noninvasive Imaging Of Acute Myocardial Infarction, Ming Zhao, Xiaoguang Zhu, Shundong Ji, Jundong Zhou, Kutlan S. Ozker, Wei Fang, Robert C. Molthen, Robert S. Hellman

Biomedical Engineering Faculty Research and Publications

Abstract: The exposure of phosphatidylserine (PtdS) is a common molecular marker for both apoptosis and necrosis and enables the simultaneous detection of these distinct modes of cell death. Our aim was to develop a radiotracer based on the PtdS-binding activity of the C2A domain of synaptotagmin I and assess ^99mTc-C2A-GST (GST is glutathione S-transferase) using a reperfused acute myocardial infarction (AMI) rat model. Methods: The binding of C2A-GST toward apoptosis and necrosis was validated in vitro. After labeling with ^99mTc via 2-iminothiolane thiolation, radiochemical purity and radiostability were tested. Pharmacokinetics and biodistribution were studied in healthy rats. …

Generalized Perceptual Linear Prediction (Gplp) Features For Animal Vocalization Analysis, Patrick J. Clemins, Michael T. Johnson

Dr. Dolittle Project: A Framework for Classification and Understanding of Animal Vocalizations

A new feature extraction model, generalized perceptual linear prediction (gPLP), is developed to calculate a set of perceptually relevant features for digital signal analysis of animalvocalizations. The gPLP model is a generalized adaptation of the perceptual linear prediction model, popular in human speech processing, which incorporates perceptual information such as frequency warping and equal loudness normalization into the feature extraction process. Since such perceptual information is available for a number of animal species, this new approach integrates that information into a generalized model to extract perceptually relevant features for a particular species. To illustrate, qualitative and quantitative comparisons are made …

Soft-Started Induction Motor Modeling And Heating Issues For Different Starting Profiles Using A Flux Linkage Abc Frame Of Reference, M. G. Solveson, Behrooz Mirafzal, Nabeel Demerdash

Electrical and Computer Engineering Faculty Research and Publications

In order to mitigate the adverse effects of starting torque transients and high inrush currents in induction motors, a popular method is to use electronically controlled soft-starting voltages utilizing series-connected silicon-controlled rectifiers (SCRs). Investigation of semioptimum soft-starting voltage profiles was implemented using a flux linkage ABC frame of reference model of a soft-started three-phase induction motor. A state-space model of the soft-starter thyristor switching sequence for the motor and load was developed and implemented in a time-domain simulation to examine winding heating and shaft stress issues for different starting profiles. Simulation results of line starts and soft starts were compared …

Sub-Banded Reconstructed Phase Spaces For Speech Recognition, Kevin M Indrebo, Richard J. Povinelli, Michael T. Johnson

Electrical and Computer Engineering Faculty Research and Publications

A novel method combining filter banks and reconstructed phase spaces is proposed for the modeling and classification of speech. Reconstructed phase spaces, which are based on dynamical systems theory, have advantages over spectral-based analysis methods in that they can capture nonlinear or higher-order statistics. Recent work has shown that the natural measure of a reconstructed phase space can be used for modeling and classification of phonemes. In this work, sub-banding of speech, which has been examined for recognition of noise-corrupted speech, is studied in combination with phase space reconstruction. This sub-banding, which is motivated by empirical psychoacoustical studies, is shown …

Alterations In Regional Vascular Geometry Produced By Theoretical Stent Implantation Influence Distributions Of Wall Shear Stress: Analysis Of A Curved Coronary Artery Using 3d Computational Fluid Dynamics Modeling, John F. Ladisa, Lars E. Olson, Douglas Anthony Hettrick, David C. Warltier, Judy R. Kersten, Paul S. Pagel

Biomedical Engineering Faculty Research and Publications

Background

The success of stent implantation in the restoration of blood flow through areas of vascular narrowing is limited by restenosis. Several recent studies have suggested that the local geometric environment created by a deployed stent may influence regional blood flow characteristics and alter distributions of wall shear stress (WSS) after implantation, thereby rendering specific areas of the vessel wall more susceptible to neointimal hyperplasia and restenosis. Stents are most frequently implanted in curved vessels such as the coronary arteries, but most computational studies examining blood flow patterns through stented vessels conducted to date use linear, cylindrical geometric models. It …

Cost Effective Concrete Pavement Cross Sections - Final Report, James Crovetti

Transportation Reports with the Wisconsin Department of Transportation

This report presents the findings of a study of alternate pavement designs targeted at reducing the initial construction costs of concrete pavements without compromising pavement performance. Test sections were constructed with alternate dowel materials, reduced dowel placements, variable thickness concrete slabs and alternate surface and subsurface drainage details. Performance data was collected out to 5 and 7 years after construction.

The study results indicate that FRP composite dowels may not be a practical alternative to conventional epoxy coated steel dowels due to their reduced rigidity, which results in lower deflection load transfer capacities at transverse joints. Ride quality measures also …

Statistical Models Of Reconstructed Phase Spaces For Signal Classification, Richard J. Povinelli, Michael T. Johnson, Andrew C. Lindgren, Felice M. Roberts, Jinjin Ye

Electrical and Computer Engineering Faculty Research and Publications

This paper introduces a novel approach to the analysis and classification of time series signals using statistical models of reconstructed phase spaces. With sufficient dimension, such reconstructed phase spaces are, with probability one, guaranteed to be topologically equivalent to the state dynamics of the generating system, and, therefore, may contain information that is absent in analysis and classification methods rooted in linear assumptions. Parametric and nonparametric distributions are introduced as statistical representations over the multidimensional reconstructed phase space, with classification accomplished through methods such as Bayes maximum likelihood and artificial neural networks (ANNs). The technique is demonstrated on heart arrhythmia …

Explant Analysis Of Total Disc Replacement, Paul A. Anderson, Steven M. Kurtz, Jeffrey M. Toth

Biomedical Engineering Faculty Research and Publications

Explant analysis of human disc prostheses allow early evaluation of the host response to the prosthesis and the response of the prosthesis from the host. Furthermore, early predictions of failure and wear can be obtained. Thus far, about 2-3% of disc prostheses have been removed. Observed wear patterns are similar to that of appendicular prostheses including abrasions/scratching, burnishing, surface deformation, fatigue, and embedded debris. Chemically the polymeric components have shown little degradation in short-term implantation. In metal on metal prostheses the histologic responses consist of large numbers of metallic particles with occasional macrophages and giant cells. Only rare cases of …

A Prototype Table-Top Inverse-Geometry Volumetric Ct System, Taly Gilat Schmidt, Josh Star-Lack, N. Robert Bennett, Samuel R. Mazin, Edward G. Solomon, Rebecca Fahrig, Norbert J. Pelc

Biomedical Engineering Faculty Research and Publications

A table-top volumetric CT system has been implemented that is able to image a 5-cm-thick volume in one circular scan with no cone-beam artifacts. The prototype inverse-geometry CT (IGCT) scanner consists of a large-area, scanned x-ray source and a detector array that is smaller in the transverse direction. The IGCT geometry provides sufficient volumetric sampling because the source and detector have the same axial, or slice direction, extent. This paper describes the implementation of the table-top IGCT scanner, which is based on the NexRay Scanning-Beam Digital X-ray system (NexRay, Inc., Los Gatos, CA) and an investigation of the system performance. …

Microswitches With Sputtered Au, Aupd,Au-On-Aupt, And Auptcu Alloy Electric Contacts, Ronald A. Coutu Jr., J. R. Reid, R. Cortez, R. E. Strawser, P. E. Kladitis

Electrical and Computer Engineering Faculty Research and Publications

This paper is the first to report on a new analytic model for predicting microcontact resistance and the design, fabrication, and testing of microelectromechanical systems (MEMS) metal contact switches with sputtered bimetallic (i.e., gold (Au)-on-Au-platinum (Pt), (Au-on-Au-(6.3at%)Pt)), binary alloy (i.e., Au-palladium (Pd), (Au-(3.7at%)Pd)), and ternary alloy (i.e., Au-Pt-copper (Cu), (Au-(5.0at%)Pt-(0.5at%)Cu)) electric contacts. The microswitches with bimetallic and binary alloy contacts resulted in contact resistance values between 1-2Omega. Preliminary reliability testing indicates a 3times increase in switching lifetime when compared to microswitches with sputtered Au electric contacts. The ternary alloy exhibited approximately a 6times increase in switch lifetime with contact resistance …

Rapid Bridge Replacement Under Emergency Situation: Case Study, Yong Bai, William R. Burkett, Phillip T. Nash

Civil and Environmental Engineering Faculty Research and Publications

The terrorist attack on September 11, 2001, and subsequent potential threats to the United States transportation systems have presented an urgent need to elevate the security of the transportation infrastructure and to develop emergency response plans to quickly react to the possible consequences of an extreme event. Highway bridges, as critical components of the nation’s transportation network, have been brought to closer attention by government agencies. A research project was conducted to identify strategies and technologies to restore the use of a damaged bridge quickly. One of the tasks associated with the research was to perform several case studies of …

Vascular Tortuosity Is Culprit To Abnormal Perfusion In 9l Gliosarcoma Tumor, M. M. Darpolar, Robert C. Molthen, F. C. Wu, Kathleen M. Schmainda

Biomedical Engineering Faculty Research and Publications

No abstract provided.

An Lmi Approach To Discrete-Time Observer Design With Stochastic Resilience, Edwin E. Yaz, Chung Seop Jeong, Yvonne I. Yaz

Electrical and Computer Engineering Faculty Research and Publications

Much of the recent work on robust control or observer design has focused on preservation of stability of the controlled system or the convergence of the observer in the presence of parameter perturbations in the plant or the measurement model. The present work addresses the important problem of stochastic resilience or non-fragility of a discrete-time Luenberger observer which is the maintenance of convergence and/or performance when the observer is erroneously implemented possibly due to computational errors i.e. round off errors in digital implementation or sensor errors, etc. A common linear matrix inequality framework is presented to address the stochastic resilient …

Spatial Admittance Selection Conditions For Frictionless Force-Guided Assembly Of Polyhedral Parts In Single Principal Contact, Shuguang Huang, Joseph M. Schimmels

Mechanical Engineering Faculty Research and Publications

By judiciously selecting the admittance of a manipulator, the forces of contact that occur during assembly can be used to guide the parts to proper positioning. This paper identifies conditions for selecting the appropriate spatial admittance to achieve reliable force-guided assembly of polyhedral parts for cases in which a single feature (vertex, edge, or face) of one part contacts a single feature of the other, i.e., all single principal contact cases. These conditions ensure that the motion that results from frictionless contact always instantaneously reduces part misalignment. We show that, for bounded misalignments, if an admittance satisfies the misalignment-reducing conditions …

Lessons Learned From An Emergency Bridge Replacement Project, Yong Bai, William R. Burkett, Phillip T. Nash

Civil and Environmental Engineering Faculty Research and Publications

The terrorist attack on September 11, 2001, and subsequent potential threats to U.S. transportation systems have presented an urgent need to develop emergency response plans to quickly react to the possible consequences of extreme events. Extreme events include terrorist attack as well as man-made and natural disasters such as explosions, fires, floods, and earthquakes. The objective of this research was to identify strategies and technologies to quickly restore the use of highway bridges, a critical component of the nation’s transportation network, in case they are damaged or destroyed by extreme events. One of the tasks associated with this research was …

Lung Circulation Modeling: Status And Prospect, Anne V. Clough, Said H. Audi, Robert C. Molthen, Gary S. Krenz

Biomedical Engineering Faculty Research and Publications

Mathematical modeling has been used to interpret anatomical and physiological data obtained from metabolic and hemodynamic studies aimed at investigating structure-function relationships in the vasculature of the lung, and how these relationships are affected by lung injury and disease. The indicator dilution method was used to study the activity of redox processes within the lung. A steady-state model of the data was constructed and used to show that pulmonary endothelial cells may play an important role in reducing redox active compounds and that those reduction rates can be altered with oxidative stress induced by exposure to high oxygen environments. In …

Fast Thermal Profiling Of Power Semiconductor Devices Using Fourier Techniques, J. J. Nelson, G. Venkataramanan, Ayman M. El-Refaie

Electrical and Computer Engineering Faculty Research and Publications

Accurate prediction of temperature variation of power semiconductor devices in power electronic circuits is important to obtain optimum designs and estimate reliability levels. Temperature estimation of power electronic devices has generally been performed using transient thermal equivalent circuits. In the presence of varying load cycles, it has been typical to resort to a time-domain electrical simulation tool such as P-Spice or SABER to obtain a time series of the temperature profiles. However, for complex and periodic load cycles, time-series simulation is time consuming. In this paper, a fast Fourier analysis-based approach is presented for obtaining temperature profiles for power semiconductors. …

Analysis Of Surface Permanent Magnet Machines With Fractional-Slot Concentrated Windings, Ayman M. El-Refaie, Thomas M. Jahns, Donald W. Novotny

Electrical and Computer Engineering Faculty Research and Publications

This paper presents a closed-form analytical technique for analyzing surface PM machines equipped with fractional-slot concentrated windings. Since this class of winding configuration deviates significantly from conventional sinusoidal distributions, classical steady-state phasor or analytical techniques cannot be used to provide accurate results. The presented analytical model provides a fast and reliable method to analyze and compare candidate machine designs. Stator slotting effects are taken into consideration and a wide range of concentrated winding configurations can be analyzed. This technique is capable of analyzing the machine both below (constant-torque) and above (flux-weakening) base speed. Average torque, cogging torque, and ripple torque …

Influence Of Pulmonary Arterial Endothelial Cells On Quinone Redox Status: Effect Of Hyperoxia-Induced Nad(P)H:Quinone Oxidoreductase 1, Marilyn P. Merker, Said H. Audi, Robert D. Bongard, Brian J. Lindemer, Gary S. Krenz

Biomedical Engineering Faculty Research and Publications

The objective of this study was to examine the impact of chronic hyperoxic exposure (95% O₂ for 48 h) on intact bovine pulmonary arterial endothelial cell redox metabolism of 2,3,5,6-tetramethyl-1,4-benzoquinone (duroquinone, DQ). DQ or durohydroquinone (DQH₂) was added to normoxic or hyperoxia-exposed cells in air-saturated medium, and the medium DQ concentrations were measured over 30 min. DQ disappeared from the medium when DQ was added and appeared in the medium when DQH₂ was added, such that after ∼15 min, a steady-state DQ concentration was approached that was ∼4.5 times lower for the hyperoxia-exposed than the normoxic …

Ischemia Reperfusion Dysfunction Changes Model-Estimated Kinetics Of Myofilament Interaction Due To Inotropic Drugs In Isolated Hearts, Samhita S. Rhodes, Amadou Ks Camara, Kristina M. Ropella, Said H. Audi, Matthias L. Riess, Paul S. Pagel, David F. Stowe

Biomedical Engineering Faculty Research and Publications

Background

The phase-space relationship between simultaneously measured myoplasmic [Ca²⁺] and isovolumetric left ventricular pressure (LVP) in guinea pig intact hearts is altered by ischemic and inotropic interventions. Our objective was to mathematically model this phase-space relationship between [Ca²⁺] and LVP with a focus on the changes in cross-bridge kinetics and myofilament Ca²⁺ sensitivity responsible for alterations in Ca²⁺-contraction coupling due to inotropic drugs in the presence and absence of ischemia reperfusion (IR) injury.

Methods

We used a four state computational model to predict LVP using experimentally measured, averaged myoplasmic [Ca²⁺] transients …

On Innovative Methods Of Induction Motor Interturn And Broken-Bar Fault Diagnostics, Behrooz Mirafzal, Nabeel Demerdash

Electrical and Computer Engineering Faculty Research and Publications

A fault indicator, the so-called swing angle, for broken-bar and interturn faults is investigated in this paper. This fault indicator is based on the rotating magnetic-field pendulous-oscillation concept in faulty squirrel-cage induction motors. Using the "swing-angle indicator," it will be demonstrated here that an interturn fault can be detected even in the presence of machine manufacturing imperfections. Meanwhile, a broken-bar fault can be detected under both direct-line and PWM excitations, even under the more difficult condition of partial-load levels. These two conditions of partial load and motor manufacturing imperfections, which are considered as difficult situations for fault detection, are investigated …

Statistical Correlation Of Gain And Buildup Time In Apds And Its Effects On Receiver Performance, Peng Sun, Majeed M. Hayat, Bahaa E.A. Saleh, Malvin Carl Teich

Electrical and Computer Engineering Faculty Research and Publications

This paper reports a novel recurrence theory that enables us to calculate the exact joint probability density function (pdf) of the random gain and the random avalanche buildup time in avalanche photodiodes (APDs) including the effect of dead space. Such calculations reveal a strong statistical correlation between the gain and the buildup time for all widths of the multiplication region. To facilitate the calculation of the photocurrent statistics in the presence of this correlation, the impulse-response function of the APD is approximately modeled by a function of time whose prespecified shape is appropriately parameterized by two random variables: the gain …

Characterization Of Metal And Metal Alloy Films As Contact Materials In Mems Switches, Hyukjae Lee, Ronald A. Coutu Jr., Shankar Mall, Kevin D. Leedy

Electrical and Computer Engineering Faculty Research and Publications

This study presents a basic step toward the selection methodology of electric contact materials for microelectromechanical systems (MEMS) metal contact switches. This involves the interrelationship between two important parameters, resistivity and hardness, since they provide the guidelines and assessment of contact resistance, wear, deformation and adhesion characteristics of MEMS switches. For this purpose, thin film alloys of three noble metals, platinum (Pt), rhodium (Rh) and ruthenium (Ru) with gold (Au), were investigated. The interrelationship between resistivity and hardness was established for three levels of alloying of these metals with gold. Thin films of gold (Au), platinum (Pt), ruthenium (Rh) and …

Detection Efficiencies And Generalized Breakdown Probabilities For Nanosecond-Gated Near Infrared Single-Photon Avalanche Photodiodes, David A. Ramirez, Majeed M. Hayat, Gauri Karve, Joe C. Campbell, Sergio N. Torres, Bahaa E.A. Saleh, Malvin Carl Teich

Electrical and Computer Engineering Faculty Research and Publications

A rigorous model is developed for determining single-photon quantum efficiency (SPQE) of single-photon avalanche photodiodes (SPADs) with simple or heterojunction multiplication regions. The analysis assumes nanosecond gated-mode operation of the SPADs and that band-to-band tunneling of carriers is the dominant source of dark current in the multiplication region. The model is then utilized to optimize the SPQE as a function of the applied voltage, for a given operating temperature and multiplication-region structure and material. The model can be applied to SPADs with In/sub 0.52/Al/sub 0.48/As or InP multiplication regions as well as In/sub 0.52/Al/sub 0.48/As--InP heterojunction multiplication regions for wavelengths …

Motivating Rehabilitation By Distorting Reality, James L. Patton, Yejun Wei, Chris Scharver, Robert V. Kenyon, Robert A. Scheidt

Biomedical Engineering Faculty Research and Publications

We have found, through a series of recent experiments, encouraging evidence that the neuro-motor system is motivated to change motor patterns when exposed to visuo-motor tasks. We have also shown that the learning of these tasks can be heightened with forces and/or visual distortions that appropriately manipulate the error. This process does not require intense concentration and it is often considered a game. We describe the next generation of robotic large-workspace, three dimensional haptics/graphics systems for rehabilitation

Resistance To Fracture Of Two All-Ceramic Crown Materials Following Endodontic Access, Kelly Copps Wood, David W. Berzins, Qing Luo, Geoffrey A. Thompson, Jeffrey M. Toth, William W. Nagy

Biomedical Engineering Faculty Research and Publications

Statement of problem

There is currently no protocol for managing endodontic access openings for all-ceramic crowns. A direct restorative material is generally used to repair the access opening, rendering a repaired crown as the definitive restoration. This endodontic procedure, however, may weaken the restoration or initiate microcracks that may propagate, resulting in premature failure of the restoration.

Purpose

The purpose of this in vitro study was to evaluate how an endodontic access opening prepared through an all-ceramic crown altered the structural integrity of the ceramic, and the effect of a repair of this access on the load to failure of …

Expanding Extracurricular Learning Opportunities Through International Engineering Student And Faculty Exchange, Mark Polczynski

Electrical and Computer Engineering Faculty Research and Publications

No abstract provided.

A Mass-Spring-Damper Model Of A Bouncing Ball, Mark L. Nagurka, Shuguang Huang

Mechanical Engineering Faculty Research and Publications

The mechanical properties of a vertically dropped ball, represented by an equivalent mass-spring-damper model, are shown to be related to impact parameters. In particular, the paper develops relationships connecting the mass, stiffness and damping of a linear ball model to the coefficient of restitution and the contact time of the ball with the surface during one bounce. The paper also shows that the ball model parameters are functions of quantities readily determined in an experiment: (i) the height from which the ball is dropped from rest, (ii) the number of bounces, and (iii) the time elapsing between dropping the ball …

Effect Of Keyswitch Design Of Desktop And Notebook Keyboards Related To Key Stiffness And Typing Force, Marcia J. Bufton, Richard W. Marklin, Mark L. Nagurka, Guy G. Simoneau

Mechanical Engineering Faculty Research and Publications

This study aimed to compare and analyse rubber-dome desktop, spring column desktop and notebook keyboards in terms of key stiffness and fingertip typing force. The spring-column keyboard resulted in the highest mean peak contact force (0.86N), followed by the rubber dome desktop (0.68N) and the notebook (0.59N). All these differences were statistically significant. Likewise, the spring-column keyboard registered the highest fingertip typing force and the notebook keyboard the lowest. A comparison of forces showed the notebook (rubber dome) keyboard had the highest fingertip-to-peak contact force ratio (overstrike force), and the spring-column generated the least excess force (as a ratio of …