Engineering Commons^™

Hand Movement Analysis For Surgical Suturing Skill Assessment, Amir Mehdi Shayan

All Theses

To enhance patient safety, surgical education is increasingly incorporating simulation for formative skills assessment and training. However, many standardized assessment tools rely on human raters for performance assessment, which is resource-intensive and subjective. Simulators that provide automated and objective metrics from sensor data can address this limitation. This thesis presents an instrumented bench suturing simulator, patterned after the Clock Face (CF) radial suturing model from the Fundamentals of Vascular Surgery (FVS), for automated and objective assessment of open suturing skills by particularly focusing on biomechanical analysis of hand movements. For this research, 97 participants (35 attending surgeons and fellows, 32 …

A Transdisicplinary, Survivor-Centered Approach For Creating A System Dynamics Model Of Closed-Buyer Sex Trafficking Networks, Kemonte Yow

All Theses

One of the largest drivers of sex trafficking operations is the demand for commercial sex. To date, research from a quantitative side typically focuses on understanding how to best identify and remove victims from their trafficking situation and then support their healing and recovery. This may be because this is where data exists (in limited forms) to support quantitative modeling. This thesis broadens that scope to understand how demand for commercial sex impacts trafficking operations. In particular, this research implemented a transdisciplinary, survivor-centered approach to build a system dynamics model of a closed-buyer sex trafficking network, which is a network …

Improved Ballistic Impact Resistance Of Nanofibrillar Cellulose Films With Discontinuous Fibrous Bouligand Architecture, Colby Caviness

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Natural protective materials offer unparalleled solutions for impact-resistant material designs that are simultaneously lightweight, strong, and tough. Particularly, the dactyl club of mantis shrimp features chitin nanofibrils organized in a Bouligand structure, which has been shown to effectively dissipate high-impact energy during powerful strikes. The mollusk shells also achieve excellent mechanical strength, toughness, and impact resistance with a staggered, layer-by-layer structure. Previous studies have shown that hybrid designs, by combining different bioinspired microstructures, can lead to enhanced mechanical strength and energy dissipation capabilities. Nevertheless, it remains unknown whether combining Bouligand and staggered structures in nanofibrillar cellulose (NFC) films, forming a …

Development Of A Cost-Affordable Thin-Layer Chromatography Testing Kit For Falsified And Substandard Pharmaceuticals In Tanzania, Eleanor Hatcher

All Theses

A significant number of pharmaceuticals supplied to Tanzania are falsified or substandard. A majority of these inadequate pharmaceuticals are medications to treat life-threatening conditions. This problem not only causes mistrust in the healthcare system but also prolonged illness and potentially death for the patients. This calls for the need for the development of a cost-affordable testing kit for falsified and substandard pharmaceuticals in Tanzania. Thin-layer chromatography (TLC) was used as the testing method since it is inexpensive and requires a low skill level to complete. Malaria, human immunodeficiency virus, hypertension, tuberculosis, and diabetes are five of the most prevalent diseases …

Evaluating Company Culture Of Roofing Contracting Companies To Attract And Retain Women In The Industry, Gopika Viswanathan

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The US construction industry, similar to many other industries, has a low representation of women. This difference is even more pronounced in construction trades, such as the roofing industry. The admission of more women into the industry is important to address workforce shortage issues that the industry is facing. Company culture has been cited as one of the primary reasons why women choose not to enter the industry or face barriers during their careers. The main objective of this study was to evaluate the company culture of roofing companies through factors identified by literature and by women and companies in …

Depression And Anxiety: Investigating The Impacts Of Scheduling On The Mental Health Of Healthcare Workers During The Covid-19 Pandemic, Christofer Gonzaga

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Depression is a growing problem in the United States and has ballooned into a globally recognized mental health issue that affects shift workers in various fields (Lee et al., 2017). Rates of depression and anxiety have been shown to be substantially increasing and the COVID-19 pandemic amplified this prevalence of depression and anxiety. In the United States, the prevalence of depression symptoms was more than 3- fold higher during COVID-19 compared to before the pandemic (Ettman et al., 2020). The delivery of healthcare services is an ongoing and dynamic process, requiring clinicians to work in various shifts to ensure the …

Phasor-Domain Short-Circuit Analysis Of Power Transmission Systems In The Presence Of Inverter-Based Resources, Dol Kunwar

All Theses

Although a power system is nonlinear during healthy operation because of constant power loads and controlled power injections from the sources, a conventional power system fed by synchronous generators is linear during fault, and can be represented by bus impedance matrix (Z-bus), which is useful in power system analyses such as short circuit (SC) analysis. However, With increasing penetration of inverter-based resources (IBRs) in the system, the assumption of linearity of the faulted network does not hold. This impacts the analyses relying on Z-bus and Thevenin’s equivalent impedance (TEI), such as certain protection schemes set using short circuit analysis. Therefore, …

The Effect Of Football Facemask Design Variability On Dynamic Impact Performance And Quasi-Static Stiffness, Adam W. Smith

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This research addresses the role of facemasks in helmet systems, focusing on their dynamic impact performance and material properties. A total of 150 facemasks from 30 types and five helmets were tested both quasi-statically and dynamically. The facemasks were grouped by style and helmet type for comparison. Dynamic testing involved three different locations and two speeds, with data collected for maximum angular velocity and linear acceleration. Quasi-static stiffness, performed at two locations, was compared with collected dynamic results to determine the strength of relationship. A concussion metric, HARM, was calculated from collected data and compared across style groups.

Significant differences …

Multi-Domain Secure Dds Networks For Aerial And Ground Vehicle Communications, Daniel Pendleton

All Theses

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A Reinforcement Learning Framework For Powertrain Control Including Shared Learning Among A Fleet Of Vehicles, Lindsey Kerbel

All Dissertations

The transportation sector provides a significant opportunity to reduce global emissions, both through technological advancements and vehicular control strategies. Model-based control systems are popular methods for increasing the operating efficiency of vehicles. However, these systems often rely on models that require costly calibrations that still fail to capture the complexity of modern powertrain systems and the variations found in real-world driving. The recent availability of operational data through connected vehicle technology and/or edge devices has led to the emergence of data-driven control strategies that can learn optimal control policies through the interactions of the vehicle’s control system with the environment. …

An In Vitro Investigation Of Urothelial Cell Function In Response To Hypoxia And Pressure In Relation To Bladder Outlet Obstruction, Britney Hudson

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Bladder outlet obstruction (BOO) is a prevalent urological condition and can be characterized by the presence of lower urinary tract symptoms (LUTS), such as hesitancy, weak stream, and nocturia. The main cause of BOO is a partial blockage of the urethra, which results in elevated voiding pressure, high storage pressure, and tissue ischemia, which are thought to be the triggers of bladder inflammation and subsequent fibrosis. Often patients do not seek treatment until the conditions get severe. Thus, it would be ideal to have an early diagnostic tool to detect changes in the bladder due to BOO. Extracellular vesicles (EVs) …

Locally Injectable Peptide Hydrogel For Conversion Of Temozolomide And Codelivery Of Sirna In Glioblastoma Multiforme Treatment, Megan Pitz

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Traditional treatment methods for glioblastoma multiforme (GBM) are largely unsuccessful, with a 5-year survival rate of 5.6%. Temozolomide (TMZ), the only chemotherapy FDA-approved for GBM treatment, is a hydrophobic prodrug that is stable in an acidic pH and begins converting to its active form at a physiological pH of 7.4. However, complete conversion of TMZ is observed only at a higher pH, and only about 30% of administered TMZ reaches the central nervous system. Therefore, there is a need for new treatment methods that maximize TMZ delivery to and efficacy at the tumor site. Self-assembling peptides are a unique class …

Optical Wavelength Measurement Based On Microwave-Photonics And Fiber Dispersion, Yongji Wu

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In modern photonics, combining microwave techniques with optical measurements has introduced a novel research direction. This study introduces a novel Microwave Photonics Wavelength Measurement System (MP-WMS), integrating microwave photonics with fiber chromatic dispersion to achieve direct wavelength measurement. Utilizing cost effective single mode optical fibers as dispersion devices, this system employs chromatic dispersion to convert optical frequency domain measurements into microwave time domain measurements. We established a mathematical model to describe how different wavelengths are detected, enhancing the system's effectiveness. The MP-WMS system offers an affordable solution with high resolution. In the experiment, we used a 35km long SM-28 single-mode …

Reinforcement Learning-Based Energy Management For Electric Vehicle Application, Yiming Ye

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The increasing concerns about transportation pollution and fossil fuel depletion motivate many studies on vehicle electrification and advanced energy-saving propulsion systems. When Comparing with traditional internal combustion engine vehicles, electrified vehicles, such as battery and supercapacitor electric vehicles, are equipped with more than one power source in the hybrid propulsion system, which can save more energy through efficient power combinations. Lithium-ion batteries are the preferred choice for energy storage in electric vehicles due to their superior energy density and cost-effectiveness. Nevertheless, matching the required power input and output leads to in an unwanted growth in the size of the battery, …

Mesenchymal Stromal Cell Response To Degenerated Intervertebral Disc-Like Ph, Kyle Cannon

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Intervertebral disc degeneration (IVDD) has become increasingly prevalent and is a common contributing factor to low back pain. There are currently no clinical treatment options for IVDD that alleviate the symptoms of IVDD while simultaneously promoting repair of IVD tissue. One treatment option being explored is intradiscal administration of mesenchymal stromal cells (MSCs). However, the microenvironment of the degenerating IVD places significant stress on both native IVD cells and implanted cells. There are several questions that need to be addressed which may help further inform the development of efficacious intradiscal MSC therapies for IVDD. These questions include: 1) Do MSCs …

Development Of Advanced Simulator-Based Metrics For Suturing Skills Assessment And Feedback, Simar Singh

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Vascular surgery demands highly skilled suturing to manipulate and connect delicate vasculature. However, inadequate methods for open suturing skills training necessitate efficient and objective methods to develop skills. To address this need, medical training simulators for objective surgical skills training are gaining popularity for their formative assessment.

This research details the development of a system to classify suturing performance and provide feedback on a suturing skills measurement and feedback platform (called the SutureCoach). The SutureCoach simulator offers a comprehensive assessment of skill through sensors measuring needle driver motions, membrane forces and torques, subcutaneous suture needle movement, and hand motions. We …

Sulfonated Ionomer Composite Membranes For Use In Vanadium Redox Flow Batteries, Xueting Wang

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While vanadium redox flow batteries (VRFBs) have garnered significant attention as a promising scalable energy storage technology, the current membrane material used in this technology, Nafion™, suffers from high cross mixing of vanadium ions in the liquid electrolytes, directly impacting battery performance properties such as the voltage and coulombic efficiencies, as well as resulting in a reduction in the overall battery lifetime. The use of ionomer nancomposites has proven to be one promising route of directly addressing the issue of high ion crossover, though the mechanism by which the nanoparticles act to reduce crossover remains in open question. Herein, the …

Development Of Earthquake Hazard Prediction Software For South Carolina And Its Applications, Vishnu Saketh Jella

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This dissertation presents the development of earthquake hazard generation software, CarolinaShake and CarolinaADRS, for the state of South Carolina and its applications in the field of earthquake engineering. South Carolina is a seismically active state in the eastern United States, and there is a need to accurately quantify the earthquake hazard and incorporate it into the design of infrastructure systems. To achieve this objective, the South Carolina Department of Transportation (SCDOT) is actively supporting the initiatives to update its seismic design policies and procedures of civil infrastructure systems. As part of those initiatives, first, CarolinaShake, a Windows-based graphical user interface …

Study Of Electrospun Nanocomposite Nanofiber Nonwoven Mats With Precursor Solutions Prepared By Ultrasonic Processing, Stephanie Tussey

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Understanding the complexity of changes in a polymer solution through the addition of nanoparticles and the process used to prepare the solutions is vitally important to obtain desirable characteristics of electrospun nanofibers such as degree of crystallinity, morphological, thermal and mechanical properties. Although there have been significant efforts in this research area, a more in-depth understanding on how nanoparticles can affect the formation of polymeric structures during electrospinning is still needed to ensure overall quality and performance of the nonwoven material. The present study aimed to specifically explore the relationship between solution processing method, nanoparticle volume fraction, and solution properties …

Investigating Bimanual Haptic Exploration With Arm-Support Exoskeletons, Balagopal Raveendranath

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The ability to judge properties like weight and length of hand-held objects is essential in industrial work. Sometimes workers use devices like exoskeletons, which can augment their ability to lift and move heavy objects. Previous studies have investigated the perceptual information available for one-handed weight and length judgments. The current study investigated how blindfolded participants bimanually heft and wield objects to explore haptic information, to perceive object heaviness or length. The study also investigated the effects of using an arm-support exoskeleton (ASE) on the perceived weight of hand-held objects. We empirically tested whether people wield and manipulate objects differently, depending …

Toxicokinetics And Toxicodynamics Of Radium-226 In An Estuarine Sentinel Species Geukensia Demissa, Sarah Donaher

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The historical use of radioluminescent objects, most notably those containing radium-226 (²²⁶Ra)-based paint, has contributed to contemporary environmental contamination of radioactive material, often near naval installations or other military-associated coastal sites. The risk to both human and environmental health from this small-scale, discrete radioactive material is challenging to predict due to large uncertainties in the source terms, bioavailability, and toxicity of these objects. The objective of this study was to provide information on the accumulation and toxicity of acute ²²⁶Ra exposure in a sentinel species to improve risk assessments for small-scale, coastal radiological contamination. The sentinel species …

Novel Nucleus Pulposus Biomaterial Development And Low Field Mri Assessment For Intervertebral Disc Degeneration, Mario Krussig

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Intervertebral disc degeneration (IVDD) is a prominent pathology in the modern world that causes debilitating pain for many patients. The onset of IVDD occurs in the nucleus pulposus (NP). NP biomaterials will play a vital role in mitigating the progression of IVDD. Within this work, we sought to synthesize a solubilized extracellular matrix (ECM)-based NP biomaterial. Utilizing pepsin or urea extraction, bovine NP ECM was successfully solubilized (SBNPs). SBNP formulations were characterized biochemically, evaluated for cytotoxicity, and down-selected for front-running formulations. Leading candidate SBNPs were incorporated into an alginate bead biomaterial model to determine the potential bioactivity with human adipose-derived …

Design, Fabrication, And Characterization Of Advanced High-Power Single-Mode 9xxnm Semiconductor Lasers, Xiaolei Zhao

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This thesis presents the comprehensive design, fabrication, and demonstration of advanced high-power, high-efficiency single-mode semiconductor lasers operating at a wavelength of 9xxnm. We begin with the design of the laser epitaxial structure, serving as the cornerstone for achieving high-power high-efficiency lasers. Our methodology integrates a semi-analytical calculation model, which accounts for Longitudinal Spatial Hole Burning (LSHB) and Two-Photon Absorption (TPA) effects, facilitating a thorough exploration of how design parameters influence output power and conversion efficiency. This approach offers an effective and time-efficient epitaxial structure optimization strategy compared to conventional full 3D simulation models.

Subsequently, we demonstrate high-power, high-efficiency ridge waveguide …

Engineering Multifunctional Silicon Nanostructures From Biorenewable Cellulose Nanocrystals, Nancy Chen

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The imperative search for alternative materials to address the pressing demand for advance energy storage is underscored by the escalating environmental predicaments. Lithium-ion batteries (LIBs) with graphite anodes have become the benchmark in energy storage; however, they are approaching a saturation point in terms of energy density. Silicon emerges as a promising contender to supplant graphite, owing to its profuse availability, cost-effectiveness, and impressive specific capacity of 4200 mAh g^-1. By integrating silicon anodes, LIBs stand to undergo a radical transformation, markedly diminishing in weight and size, thus heralding a novel wave of compact, lightweight energy storage systems. …

Development And Application Of Discrete Element Models For Granular Materials - From Rigid Spheres To Complex-Shaped Flexible Particles With Breakage, Zakia Tasnim

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Granular materials, which can range from nanometers to centimeters, are widely encountered as particles or powders in nature and in engineered systems. Some examples of granular materials include sands, gravels, biomass feedstocks, rice grains, pharmaceutical pills, glass beads, and lunar or martian regolith simulants. The attributes of and the interactions between constituent particles dictate the bulk mechanical properties and behavior of granular materials. The discrete element method (DEM), a particle-based modeling technique, has become a useful numerical tool for modeling the bulk behavior (such as mechanical, flow, and breakage behavior) of granular materials, where interactions between the granular materials' individual …

Process-Structure-Property-Performance Modeling For Semicrystalline Thermoplastics And Composites, Tatiana Stepanova

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With a growing focus on reducing the adverse effects of transportation on the environment, industries are seeking fuel-efficient and sustainable solutions. Fuel efficiency can be improved in several ways, but structural lightweighting has demonstrated overall effectiveness. In this regard, thermoplastic composites and additive manufacturing (AM) thermoplastics have become viable candidates for use in the automotive industry, given the need for weight reduction and efficiency improvement.

The advantages of AM include simplifying supply chains, simplifying part geometry, and enabling mass customization. In order to design high-performance AM structures, extensive modeling and simulation are required. AM thermoplastics are similar to conventional manufacturing …

A Manufacturing-To-Response Pathway For Manufacturing Optimization Of Carbon Fiber Reinforced Polymer Composite Structures, Madhura Limaye

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Over the past decade, there has been an increased adoption of thermoplastic and thermoset based continuous carbon fiber reinforced polymer (CFRP) composites for structural applications in several industries. Among the different manufacturing methods, thermoforming process for thermoplastic based continuous CFRP’s offer a major advantage in reducing cycle times for large scale productions. Similarly, out-of-autoclave curing process for thermoset based continuous CFRP’s using heated tooling enables production of large composite structures. However, these manufacturing processes can have a significant impact on the structural performance of parts by inducing undesirable effects. These effects include inhomogeneous fiber orientations, thickness variations, and residual stresses …

Additive Manufacturing With Bioresorbable Polymers: Process-Structure-Property Relationships For Biomimetic Tissue Scaffolds, Clayton Joseph Culbreath

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Tissue engineering has a base requirement of scaffold structures to support cell growth, proliferation, and regeneration. However, attempts to use artificial scaffold structures have often fallen short of clinical needs to justify the change away from the established, biologic-based current standard of care. Based on the limited number of successful tissue scaffolds produced by material extrusion modes of additive manufacturing, fused filament 3d printing and electrospinning, critical design specifications for a tissue scaffold are six minimum requirements: 1) biocompatibility, 2) porosity, 3) mechanical properties, 4) bioresorbable medical grade materials, 5) bioactivity, and 6) appropriately scaled production methods compliant with medical …

Machine Learning Assisted Discovery Of High-Performance Perovskites For Hydrogen Production, Ximei Zhai

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Hydrogen has significantly contributed to the global energy transition as a clean energy carrier. However, traditional hydrogen production involves energy-intensive processes with heavy carbon emissions. High-temperature water splitting to generate hydrogen has become a promising route for clean hydrogen production. Directly utilizing concentrated solar heat to perform solar thermochemical hydrogen (STCH) production is considered one of the most eco-friendly hydrogen production options. At the same time, high-temperature electrolysis in protonic ceramic electrolysis cells (PCECs) can efficiently utilize intermittent and cost-effective renewable electricity to produce hydrogen. Perovskite oxides with good redox capability and tolerance for oxygen deficiency are considered the most …

Multi-Scale Modeling Of Selective Laser Sintering: From Manufacturing Process And Microstructure To Mechanical Performance In Semi-Crystalline Thermoplastics, Cameron Zadeh

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Selective laser sintering is an additive manufacturing process that opens many design possibilities but is limited in its reliability and reproducibility. Numerical simulations validated by experimental data yield insights into the process and resulting part properties, allowing users to make more informed decisions. In this dissertation, a model for the process and microstructure is developed and validated, followed by a coupling to mechanical models to predict part performance. Further developments include a new addition of a reaction kinetics model to the process model to describe the interplay between thermal degradation and melt pool properties, and an exploration of the parameter …