Engineering Commons^™

In Vitro Simulation Of Pathological Bone Conditions To Predict Clinical Outcome Of Bone Tissue Engineered Materials, Duong Nguyen

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According to the Centers for Disease Control, the geriatric population of ≥65 years of age will increase to 51.5 million in 2020; 40% of white women and 13% of white men will be at risk for fragility fractures or fractures sustained under normal stress and loading conditions due to bone disease, leading to hospitalization and surgical treatment. Fracture management strategies can be divided into pharmaceutical therapy, surgical intervention, and tissue regeneration for fracture prevention, fracture stabilization, and fracture site regeneration, respectively. However, these strategies fail to accommodate the pathological nature of fragility fractures, leading to unwanted side effects, implant failures, …

Predictive Maturity Of Inexact And Uncertain Strongly Coupled Numerical Models, Ismail Farajpour

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The Computer simulations are commonly used to predict the response of complex systems in many branches of engineering and science. These computer simulations involve the theoretical foundation, numerical modeling and supporting experimental data, all of which contain their associated errors. Furthermore, real-world problems are generally complex in nature, in which each phenomenon is described by the respective constituent models representing different physics and/or scales. The interactions between such constituents are typically complex in nature, such that the outputs of a particular constituent may be the inputs for one or more constituents. Thus, the natural question then arises concerning the validity …

Knowledge Extraction From Work Instructions Through Text Processing And Analysis, Abhiram Koneru

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The objective of this thesis is to design, develop and implement an automated approach to support processing of historical assembly data to extract useful knowledge about assembly instructions and time studies to facilitate the development of decision support systems, for a large automotive original equipment manufacturer (OEM). At a conceptual level, this research establishes a framework for sustainable and scalable approach to extract knowledge from big data using techniques from Natural Language Processing (NLP) and Machine Learning (ML). Process sheets are text documents that contain detailed instructions to assemble a portion of the vehicle, specification of parts and tools to …

Optimal Retrofit Strategy Design For Highway Bridges Under Seismic Hazards: A Case Study Of Charleston, Sc, Shawn Parmelee

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A significant number of US highway bridges are inadequate for seismic loads and could be seriously damaged or collapse during a relatively small earthquake. On the most recent infrastructure report card from the American Society of Civil Engineers (ASCE), one-third of the bridges in the United States are deemed to be structurally deficient. To improve this situation, at-risk bridges must be identified, evaluated, and effective retrofitting programs implemented to reduce their seismic vulnerabilities. In practice, the Federal Highway Administration uses the expected damage method and indices method to assess the condition of bridges. These methods compare the severity of expected …

Effects Of Iteration On Concept Development, Shivraj Ranganathan

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Iteration in the conceptual design stage is defined as repetition of design tasks to incorporate new information. A more concise definition of iteration relevant to this research would be the progression of design through different abstraction levels or design stages, defining and refining design solutions while progressing from initial concepts to a more detailed design. Although it is believed that iteration has a positive effect on the quality of ideas in the design process, this experimental study presents an opportunity to determine the effects of iteration on quality of concepts and the factors that lead to increased quality of concepts. …

Knowledge Base Representation With Axiomatic Design Rules For Concept Level Up Implement In Ontological Framework, Zhuochen Shi

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Axiomatic Design has been applied and developed as a tool, offering a scientific basis for design and improving design activities. Axiomatic Design has been used in various fields such as software system design, structure design, and product design. However, several challenges and limitations exist in Axiomatic Design including: the inconsistency in identifying design parameters, existence of coupled design, and multiple groups of functional requirements and design parameters. Aimed at using Axiomatic Design to generate conceptual solutions in engineering design while overcoming its limitations, a formal ontology is developed. The ontology defines functional requirements, design parameters, concepts, components and variables and …

Twelve Mile Creek Channel Morphology, Substrate Composition, And The Macroinvertebrate Community Changes Resulting From Multiple Dam Removals, Patricia Whitener

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Dam removal is gaining global attention as a potential restoration tool for impacted rivers. As the practice of dam removal increases, physical, chemical and biological monitoring before and after dam removal is essential to our understanding of the ecological consequences of this type of disturbance. Under the Lake Hartwell Restoration and Compensation Determination Plan, two dams (>9 m height) were removed from the Twelve Mile Creek watershed (170 km2) in Pickens county, South Carolina. To assess the short term impacts of dam removal on the Twelve Mile Creek ecosystem we conducted biomonitoring of macroinvertebrate species and surveys of river …

Scratch Damage Evolution On Metals In Total Joint Replacements, Caleb Eljach

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The goal of total joint replacement (TJR) is to replace nonfunctioning joint components and relieve pain, improve quality of life, and to improve joint function. Although TJR is a successful procedure, more than 54,000 knee revisions occur each year due to factors, such as wear, loosening, infection, fracture, instability, and patient related factors (Ranawat, 2010). TJRs consist of components typically composed of polyethylene and a metallic counterface (Navarro, 2008). The sliding contact that occurs between the metal and polyethylene components has been well studied and is shown to produce both surface damage and wear of the implant components (Barbour, 1997; …

Dissolved Carbon Dioxide For Scale Removal In Reverse Osmosis, Erin Partlan

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Membrane fouling is a major operational issue in reverse osmosis (RO) desalination plants. In particular, plants treating brackish groundwater can encounter troublesome inorganic scales, including carbonates, sulfates, and silicates. A novel cleaning method is proposed to remove inorganic scales from fouled RO membranes usinag dissolved CO ₂ . As CO₂ molecules encounter membrane foulants, the surfaces serve as nucleation sites for small bubbles to form and shear off foulants. Dissolved CO₂ solutions were prepared by bubbling CO₂ gas into water held in a pressure vessel. Gas dissolution was confirmed by enhanced exit velocities for water containing CO …

Adaptive Transmission For Ofdm, Michael Juang

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To respond to dynamic channel conditions caused by fading, shadowing, and other time-varying disturbances, orthogonal frequency division multiplexing (OFDM) packet radio systems should adapt transmission parameters on a packet-by-packet basis to maintain or improve performance over the channel. For this to be possible, there are three key ideas that must be addressed: first, how to determine the subchannel conditions; second, which transmission parameters should be adapted; and third, how to adapt those parameters intelligently. In this thesis, we propose a procedure for determining relative subchannel quality without using any traditional channel measurements. Instead, statistics derived solely from subcarrier error counts …

Improvements In The Process Of Biohydrogen Production By Thermotoga Neapolitana, Louis Hill

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The production of biological hydrogen is an important process for the future of sustainability and alternative energies. Thermotoga neapolitana is a hyperthermophilic bacterium that produces H ₂ , CO₂ and acetate via fermentation. The goal of the research was to investigate the sustainable production of H₂ gas using waste agricultural feedstocks, recycled water and a simplified N₂ sparging method technique. A limited sparging method was developed which includes 1 minute of N₂ gas sparging of the reactor headspace and 90 minutes of idle reaction time for cysteine-HCl to react with dissolved oxygen prior to inoculation. This …

Evaluating The Predictive Capability Of Numerical Models Considering Robustness To Non-Probabilistic Uncertianty In The Input Parameters, Parker Shields

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The paradigm of model evaluation is challenged by compensations between various forms of errors and uncertainties that are inherent to the model development process due to, for instance, imprecise model input parameters, scarcity of experimental data and lack of knowledge regarding an accurate mathematical representation of the system. When calibrating model input parameters based on fidelity to experiments, such compensations lead to non-unique solutions. In turn, the existence of non-unique solutions makes the selection and use of one `best' numerical model risky. Therefore, it becomes necessary to evaluate model performance based not only on the fidelity of the predictions to …

Functional Stroke Recovery Through Tissue Engineered Niche Neural Constructs, Natasha Topoluk

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According to the Centers for Disease Control and Prevention, stroke is statistically responsible for 1 in every 19 deaths of American citizens.5 Stroke is the leading cause of permanent disability due to the fact that it compromises both cellular and tissue components of the brain, leading to the formation of a physical void within the tissue. Current research approaches address the cellular component by injecting stem cells into this void; however, extremely low cell engraftment, high injected cell death, and overall no matrix regeneration are observed. Additionally, these stem cells do not remain committed to a neural lineage. We propose …

Analyzing Requirement Type Influence On Generated Solutions, Emily Worinkeng

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Several ideation methods are available and used by engineering designers to enable the generation of alternative designs [1]. However, there has been little work done to understand the role that the design problem given to participants plays in the ideation process. The contribution of this research is found through the proposed guidelines with respect to the type of requirements to include as part of the design problem in order to achieve the desired quantity, quality, novelty, and variety of solutions during the early stages of the design process. This work is the first attempt at analyzing the effect of requirement …

A Study Of Gallery Method To Increase Idea Quality In Conceptual Design, Liz Mathew

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The objective of this research is to evaluate whether gallery method increases idea quality in conceptual design for engineering design problems. The gallery method is a group ideation process which allows individuals to first generate ideas individually, followed by pooling of ideas to conduct group ideation. Design engineers are often encouraged to work in groups to generate concepts and solutions for design problems. However, past research argues that individual ideation results in higher quality design concepts compared to the group ideation methods. The limitations of group ideation such as free riding, production blocking, evaluation apprehension, and goal incongruity are identified …

Bite Detection And Differentiation Using Templates Of Wrist Motion, Soheila Eskandari

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We introduce a new algorithm of bite detection during an eating activity based on template matching. The algorithm uses a template to model the motion of the wrist over a 6-second window centered on the time when a person takes a bite. We also determine if different types of bites (for example food vs. drink, or using different types of utensils) have different wrist motion templates. This method is implemented on 22,383 bites and 5 different types of templates are built. We then describe a method to recognize different types of bites using the set of templates. The obtained accuracy …

An Exploratory Study On The Effects Of Goal Alignment, Interventions, And Motivational Factors On Innovative Engineering Design Projects, Blake Linnerud

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Innovation has become an important facet of engineering design, both in industry and the academy. Many senior-level engineering design courses encourage students to develop innovative solutions to open design projects from industry sponsors. Like industry, these academic problems are tackled by teams of students. Student teams that function at the highest level are more likely to reach the innovative solutions for which they are searching. The research presented in this work focuses on two main areas: (1) understanding what motivates engineers when working on innovative design projects and (2) determining the effects of goal alignment interventions on design teams working …

The Effects Of Different Size Gold Nanoparticles On Mechanical Properties Of Vascular Smooth Muscle Cells Under Mechanical Stretching, Tri Kieu

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The field of nanotechnology research has seen a large growth in the past few decades due to the great potential of novel nano-size material for useful applications such as drug delivery and medical imaging. Also, they are a promising platform for the detection of terrible diseases such as cancer and atherosclerosis. Although these materials hold great promise, there is very limited understanding about the biological effects of these nanoparticles on normal healthy cells, such as vascular smooth muscle cells (VSMCs). The VSMCs are unique cells due to the two distinct phenotype characteristics it can express: a contractile and a synthetic …

Evaporation And Modeling Water Availability In The Savannah River Basin, Ryne Phillips

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Four methods for estimating lake evaporation are presented and compared. Three are mass transfer methods that incorporated high resolution satellite imagery obtained from the MODIS sensor on the Terra and Aqua satellites. The fourth is the traditional pan method, which used monthly derived pan coefficients and pan evaporation measurements from a Class A evaporation pan located in Clemson, SC.

The four evaporation methods were used to estimate lake evaporation from the five major lakes in the Savannah River Basin for a period of more than one decade. Analysis of the evaporation rates clearly illustrated the uncertainty in daily, monthly, and …

Safety And Operational Characteristics Of Lane Widths On Urban And Rural Roadways A Simulator Study, Meredith Ladue

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The primary goal for this study was to further evaluate and assess the effect of lane width on the safety and operation of roadways in South Carolina. Due to various site conditions that affect the safety and operations of roadways, highway design engineers often face many challenges when developing appropriate road design standards. To investigate specific site conditions for the South Carolina Department of Transportation (SCDOT) a research study took place. In 2011, Part 1 of this research included field studies conducted by Kevin Baumann and Trey Jordan. Due to the various limitations of the field studies it was evident …

Rapid Riparian Buffer Width And Quality Analysis Using Lidar In South Carolina, Emre Akturk

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The importance of protecting water quality and aquatic resources are increasing because of harmful human impacts within and around waterways. Establishing or restoring functional riparian areas protect water quality and are a good mechanism to conserve aquatic systems, plants, and wildlife. Laser-based remote sensing technology offers a high resolution approach to both characterize and document changes in riparian buffer zones (RBZs). The objectives of this study were to build a model to calculate riparian buffer width on both sides of a stream using a LiDAR-derived slope variable, to classify riparian buffers and determine their quality, and to evaluate the appropriateness …

Uv-Assisted Stabilization Of Polyacrylonitrile-Based Carbon Fiber Precursors, Marlon Salvador Morales Sandoval

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Due to their high strength and stiffness coupled with low density, carbon fibers are the preferred reinforcing fibers used in high-performance polymer matrix composites. Consequently, the demand for carbon fibers is expected to grow from 40,000 metric tons to about 150,000 metric tons over the next decade. A large fraction of the increase is anticipated in the industrial sector that is cost-sensitive. Therefore, there is a need for the development of novel processes and precursors to reduce the carbon fiber production cost and expand the use of carbon fibers. This research focuses on the development of an alternative, rapid stabilization …

Enhancing Energy Efficiency In Connected Vehicles Via Access To Traffic Signal Information, Grant Mahler

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This dissertation expounds on algorithms that can deterministically or proba-bilistically predict the future Signal Phase and Timing (SPAT) of a traffic signal by relying on real-time information from numerous vehicles and traffic infrastructure, historical data, and the computational power of a back-end computing cluster. When made available on an open server, predictive information about traffic signals’ states can be extremely valuable in enabling new fuel efficiency and safety functionalities in connected vehicles: Predictive Cruise Control (PCC) can use the predicted timing plan to calculate globally optimal velocity trajectories that reduce idling time at red signals and therefore improve fuel efficiency …

Pyrene Oligomers: Their Isolation, Molecular Characterization, And Phase Behavior, David Esguerra Taborda

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Carbonaceous pitches can serve as attractive precursors for advanced carbon materials such as high thermal conductivity fibers or carbon-carbon composites. Yet the effects of composition and molecular structure on the bulk properties (e.g., mesophase content and melting point) of these precursors remain only partly known, mainly because of the difficulties associated with the isolation, identification, and quantification of the large (i.e., molecular weight (mol wt) > 350-400 Da) polycyclic aromatic hydrocarbon (PAH) oligomers comprising these pitches. In this study, oligomeric fractions were isolated via supercritical extraction (SCE) from two representative pitches: a petroleum pitch (M-50) produced by the thermal polymerization of …

Optimization Of Porous Pavement Mixtures Based On Aggregate Structure, Andrew Neptune

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Porous pavements are sustainable features that are used to help manage the quantity and quality of stormwater runoff. These pavements may include porous asphalt, permeable interlocking concrete pavers and pervious concrete. Since pavements that are purposefully designed to drain water through their matrix are relatively new, contractors and engineers are faced with various challenges such as improper design and installation, poor workability, and excessive finishing which may lead to clogged pores. Therefore, this study on porous pavements examined pervious concrete mixtures to evaluate an optimization process for the preparation of porous pavement mixtures based on aggregate structure to meet desired …

Synthesis And Characterization Of Polymer Layers For Control Of Fluid Transport, Fehime Vatansever

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The level of wetting of fiber surface with liquids is an important characteristic of fibrous materials. It is related to fiber surface energy and the structure of the material. Surface energy can be changed by surface modification via the grafting methodologies that have been reported for introducing new and stable functionality to fibrous substrates without changing bulk properties.

Present work is dedicated to synthesis and characterization of macromolecular layers grafted to fiber surface in order to achieve directional liquid transport for the modified fabric. Modification technique used here is based on formation of stable polymer layer on fabric surface using …

Vascular Nanomedicine: Site Specific Delivery Of Elastin Stabilizing Therapeutics To Damaged Arteries, Aditi Sinha

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Elastin, a structural protein in the extra-cellular matrix, plays a critical role in the normal functioning of blood vessels. Apart from performing its primary function of providing resilience to arteries, it also plays major role in regulating cell-cell and cell-matrix interactions, response to injury, and morphogenesis. Medial arterial calcification (MAC) and abdominal aortic aneurysm (AAA) are two diseases where the structural and functional integrity of elastin is severely compromised. Although the clinical presentation of MAC and AAA differ, they have one common underlying causative mechanism--pathological degradation of elastin. Hence prevention of elastin degradation in the early stages of MAC and …

Assessing Potential Environmental Impacts According To Probable Patterns Of Switchgrass Adoption In The Southeastern Us, Benjamin Sharp

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To assess the overall net impact of an emerging technology, life cycle assessment (LCA) must be accompanied by projections of adoption. Diffusion of innovation research provides tools that incorporate economic and social variables to explain and forecast integration of technologies. A switchgrass-to-ethanol case study for the southeastern U.S. is used to demonstrate methods for gauging aggregate environmental effects of an emerging energy technology. Before applying diffusion concepts, breakeven capacities are calculated for land in row crops, hay, pasture and marginal land. Breakeven curves are generated to provide upper bounds to switchgrass adoption over a range of farm-gate prices. The amount …

Study On Electromagnetic Scattering Of Cylinders Buried In A Half Space With Random Rough Surfaces Of Finite/Infinite Length, Yueyang Dai

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Analysis of electromagnetic scattering of buried objects is a subject of great interest due to its practical importance in both military and civil applications, such as subsurface investigation and target detection. In reality, the earth is of layered structure of random rough interfaces, which leads to a greatly increased complexity of the analysis. However, it is necessary to incorporate the nature of random rough surface and the layered structure because they both have substantial impact on the scattered signature and hence affect the study of inverse scattering and detection of buried objects. In this dissertation, a Monte-Carlo multidomain pseudospectral time …

Biological Scaffolds For Peripheral Vascular Surgery, George Fercana

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The gold standards for small diameter peripheral vascular graft replacement are autologous arteries or veins; however, one-third of patients lack such vessels due to previous vessel harvesting or advanced vascular disease. A promising approach for patients in this category is tissue engineering with off-the-shelf biological vascular grafts. Three small diameter acellular scaffolds were developed and evaluated as vascular grafts. Porcine renal arteries (2-3 mm diameter, 20 mm length) were decellularized by immersion and stabilized with penta-galloyl glucose (PGG) with and without subsequent heparinization via carbodiimide chemistry. Bovine mammary (4-6 mm ID, 250 mm length) and femoral arteries (6-8 mm ID, …