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Articles 5281 - 5310 of 193505

Full-Text Articles in Engineering

Unsupervised Transfer Learning And Its Applications In Human Pose Estimation, Qucheng Peng Jan 2026

Unsupervised Transfer Learning And Its Applications In Human Pose Estimation, Qucheng Peng

Graduate Studies Theses and Dissertations 2026

This dissertation advances unsupervised transfer learning by addressing critical constraints in data privacy, intellectual property protection, and deployment in unseen environments. We propose novel frameworks for three progressively restrictive settings: Black-Box Domain Adaptation (BBDA), Source-Free Domain Adaptation (SFDA), Domain Generalization (DG), and Lifelong Domain Adaptation (LLDA) for 3D human pose estimation (HPE). To address BBDA, where only model outputs are accessible, we introduce RAIN (Regularization on Input and Network). This framework utilizes Phase MixUp for frequency-domain input regularization and Subnetwork Distillation to combat source overfitting.

Extending these privacy-preserving paradigms to spatial tasks, we present the first SFDA framework for HPE. …


Computational Regolith Mechanics And Instrumentation Development For Lunar Exploration And Resource Utilization, Jared M. Long-Fox Jan 2026

Computational Regolith Mechanics And Instrumentation Development For Lunar Exploration And Resource Utilization, Jared M. Long-Fox

Graduate Studies Theses and Dissertations 2026

Sustained exploration of the Moon requires quantitative understanding of lunar regolith properties to support scientific investigation, in situ resource utilization, excavation, and infrastructure development. This dissertation examines the mechanical interaction between robotic excavation systems and lunar regolith, emphasizing how regolith behavior both enables and constrains exploration-focused and exploration-enabled science. Computational excavation models were compared to laboratory data to evaluate prediction of excavation forces and to develop metrics of excavation efficiency. Laboratory experiments using high-fidelity lunar regolith simulants were conducted to characterize pressure-sinkage behavior, shear strength, and angle of repose across a range of material states. Common analytical excavation and terramechanics …


From Recommender To Actor: The Normative Boundary When Rag Tools Become Tool-Calling Agents, Md Tahmid Rashid Jan 2026

From Recommender To Actor: The Normative Boundary When Rag Tools Become Tool-Calling Agents, Md Tahmid Rashid

Faculty Publications - Information Technology

Retrieval-Augmented Generation (RAG) systems increasingly operate not only as tools for retrieving and synthesizing information, but also as agents that can invoke external functions, modify digital environments, and execute tasks across software systems. This development raises a specific normative problem: the point at which a model’s output ceases to be merely informational and becomes an executable intervention in the world. Building on existing work in Responsible AI, accountability, and human oversight, this paper argues that tool-calling architectures place particular pressure on these frameworks because they can fuse retrieval, reasoning, and action within a single operational pipeline. To clarify this transition, …


Watch Your Step, Mind The Crowd: Socially Compliant Navigation In Unstructured Environments, Jack Vice Jan 2026

Watch Your Step, Mind The Crowd: Socially Compliant Navigation In Unstructured Environments, Jack Vice

Graduate Studies Theses and Dissertations 2026

Autonomous mobile robots increasingly operate in complex real-world environments characterized by uneven terrain, dynamic obstacles, and human presence. This dissertation addresses the fundamental challenge of developing adaptive navigation strategies that enable robots to safely and effectively traverse unstructured outdoor environments including construction sites, agricultural fields, and disaster areas while maintaining social compliance around people. We advance this capability through five complementary contributions that collectively target dynamic, unstructured, human-occupied environments. First, we demonstrate evolutionary optimization of legged mobility for uneven terrain. Second, we propose using a spatiotemporal autoencoder to learn the temporal dynamics of moving people and objects. Third, we introduce …


Circulating Biomarker Results From A Phase 2 Study Of Seralutinib In Pulmonary Arterial Hypertension, Robin Osterhout, Athénaïs Boucly, Raymond L. Benza, Richard N. Channick, Kelly M. Chin, Robert P. Frantz, Anna R. Hemnes, Luke S. Howard, Vallerie V. Mclaughlin, Olivier Sitbon, Jean-Luc Vachiéry, Rotham T. Zamanian, Richard Aranda, Matt Cravets, Zhaoqing Ding, Thao Duong-Verlé, David Mattola, Robert F. Roscigno, Ravikumar Sitapara, Lawrence S. Zisman, Jean-Marie Bruey, Hossein-Ardeschir Ghofrani Jan 2026

Circulating Biomarker Results From A Phase 2 Study Of Seralutinib In Pulmonary Arterial Hypertension, Robin Osterhout, Athénaïs Boucly, Raymond L. Benza, Richard N. Channick, Kelly M. Chin, Robert P. Frantz, Anna R. Hemnes, Luke S. Howard, Vallerie V. Mclaughlin, Olivier Sitbon, Jean-Luc Vachiéry, Rotham T. Zamanian, Richard Aranda, Matt Cravets, Zhaoqing Ding, Thao Duong-Verlé, David Mattola, Robert F. Roscigno, Ravikumar Sitapara, Lawrence S. Zisman, Jean-Marie Bruey, Hossein-Ardeschir Ghofrani

Department of Medicine Faculty Publications

[Introduction] To the Editor: Pulmonary arterial hypertension (PAH) is a progressive disease characterized by obstructive pulmonary arterial remodeling (1). Seralutinib, an investigational inhaled tyrosine kinase inhibitor, potently and selectively targets kinases relevant to PAH pathobiology including platelet-derived growth factor receptors (PDGFR) α and β, colony stimulating factor 1 receptor (CSF1R), and mast/stem cell growth factor receptor kit (c-KIT) (2). In preclinical models, seralutinib improved cardiopulmonary hemodynamics, reversed pulmonary vascular pathology and decreased right ventricular hypertrophy (3). In TORREY, a phase 2, multicenter, double-blind, randomized, placebo-controlled trial in PAH, seralutinib significantly reduced pulmonary vascular resistance (PVR) after 24 weeks with good …


Super-Resolution Learning Inspired Spectral-Spatial Correlation Network For Hyperspectral Target Detection, Jiaping Zhong, Yunsong Li, Jianxin Li, Yanzi Shi, Weiying Xie, Paolo Gamba Jan 2026

Super-Resolution Learning Inspired Spectral-Spatial Correlation Network For Hyperspectral Target Detection, Jiaping Zhong, Yunsong Li, Jianxin Li, Yanzi Shi, Weiying Xie, Paolo Gamba

Research outputs 2022 to 2026

Hyperspectral target detection (HTD) aims at extracting targets from complex backgrounds while overcoming noise interference. Existing deep learning models for HTD usually suffer from low spatial resolution and unitary representation, especially in space-borne platforms. Super-resolution, as a critical technology to enhance the spatial details, could effectively address the aforementioned issue. To make super-resolution absolutely pose positive effects on target detection, this paper proposes an end-to-end novel super-resolution learning inspired spectral-spatial correlation network for hyperspectral target detection (SR-HTD) from the perspective of spatial and spectral regularization to achieve high-precision detection. Specifically, we designed a Spatial Correlation Aggregation (SCA) module inspired by …


Multi-Scale Sensor-Aware Variational Autoencoders For Adaptive Iot Security: Integrating Drift Calibration And Cyberattack Detection, Md Kamal Hossain, Iftekhar Ahmad, Daryoush Habibi Jan 2026

Multi-Scale Sensor-Aware Variational Autoencoders For Adaptive Iot Security: Integrating Drift Calibration And Cyberattack Detection, Md Kamal Hossain, Iftekhar Ahmad, Daryoush Habibi

Research outputs 2022 to 2026

Existing approaches to Industrial Internet of Things (IoT) anomaly detection treat sensor drift calibration and cyberattack detection as separate problems, overlooking their strong interdependence and the compound failure modes that arise when drift dynamics are exploited by stealthy adversaries. Industrial Internet of IoT sensor networks therefore require a unified framework that jointly models both phenomena. This paper proposes the first unified multi-scale sensor-aware variational autoencoder (MS-VAE) framework that jointly models sensor drift and malicious activity within shared latent representations, enabling integrated calibration and security monitoring. The framework introduces three key components: (i) a multi-scale latent architecture that captures short-term anomalies …


Covert Performance Of Star-Ris Aided Thz Communication System With Rsma And Phase Errors, Xiangbin Yu, Yue Zhou, Shihao Yan, Yun Rui, Xiaoyu Dang, Chau Yuen, Mohsen Guizani Jan 2026

Covert Performance Of Star-Ris Aided Thz Communication System With Rsma And Phase Errors, Xiangbin Yu, Yue Zhou, Shihao Yan, Yun Rui, Xiaoyu Dang, Chau Yuen, Mohsen Guizani

Research outputs 2022 to 2026

In this paper, the covert performance of the simultaneous transmitting and reflecting reconfigurable intelligent surface (STAR-RIS) aided Terahertz (THz) communication systems with rate-splitting multiple access (RSMA) over the generalized α-μ fading channel is studied, where the discrete phase error and noise power uncertainty are considered. By means of the Gaussian approximation and Gamma distribution, the closed-form outage probability (OP) of the legitimate users is firstly derived. Then, the covert performance of the system is analyzed, and average detection error probability (ADEP) is deduced for the warden, and resultant closed-form ADEP is obtained. By minimizing the ADEP, the optimal detection threshold …


Sensing-Then-Beamforming: Robust Transmission Design For Ris-Empowered Integrated Sensing And Covert Communication, Xingyu Zhao, Min Li, Ming Min Zhao, Shihao Yan, Min Jian Zhao Jan 2026

Sensing-Then-Beamforming: Robust Transmission Design For Ris-Empowered Integrated Sensing And Covert Communication, Xingyu Zhao, Min Li, Ming Min Zhao, Shihao Yan, Min Jian Zhao

Research outputs 2022 to 2026

Traditional covert communication often relies on the knowledge of the warden's channel state information, which is inherently challenging to obtain due to the non-cooperative nature and potential mobility of the warden. The integration of sensing and communication technology provides a promising solution by enabling the legitimate transmitter to sense and track the warden, thereby enhancing transmission covertness. In this paper, we develop a framework for sensing-then-beamforming in reconfigurable intelligent surface (RIS)-empowered integrated sensing and covert communication (ISACC) systems, where the transmitter (Alice) estimates and tracks the mobile aerial warden's channel using sensing echo signals while simultaneously sending covert information to …


Ai-Enhanced Smart Sensors For Heavy Metal Detection In Water Treatment, Fatemeh Noorisafa, Amir Razmjou, Asghar Taheri-Kafrani, Fatemeh Ejeian, Mohsen Asadnia, Hamidreza Akbari Ghavamabadi Jan 2026

Ai-Enhanced Smart Sensors For Heavy Metal Detection In Water Treatment, Fatemeh Noorisafa, Amir Razmjou, Asghar Taheri-Kafrani, Fatemeh Ejeian, Mohsen Asadnia, Hamidreza Akbari Ghavamabadi

Research outputs 2022 to 2026

Artificial intelligence (AI) enhances biosensor design by efficiently processing and modeling environmental data. This study employs machine learning algorithms to optimize biosensor parameters for the detection of trace-level heavy metals in aquatic environments, utilizing enzymes, DNAzymes, and aptamers as recognition elements. Machine learning models, including decision trees, random forests, gradient boosting, ensemble neural networks, and GLMM,were trained on extensive laboratory datasets. Among these, the random forest model exhibited the highest predictive accuracy, achieving 71 % for the limit of detection (LOD), 75 % for the minimum concentration of linearity, and 62 % for the maximum concentration of linearity. The AI-driven …


Experimental Investigation And Performance Optimization Of A Double Slope Solar Still Integrated With Nanoparticles In Phase Change Materials, Pronob Das, Md Shahriar Mohtasim, Utpol K. Paul, Md Sanowar Hossain, Barun K. Das, Anik Saha, Md Golam Kibria Jan 2026

Experimental Investigation And Performance Optimization Of A Double Slope Solar Still Integrated With Nanoparticles In Phase Change Materials, Pronob Das, Md Shahriar Mohtasim, Utpol K. Paul, Md Sanowar Hossain, Barun K. Das, Anik Saha, Md Golam Kibria

Research outputs 2022 to 2026

By utilizing solar energy for desalination, solar stills offer a sustainable and cost-effective means of providing fresh drinking water in remote and arid regions. Existing studies have primarily focused on improving freshwater productivity while considering economic and environmental feasibility. The present work offers an in-depth assessment of solar still (SS) systems by analyzing energy and exergy performance, exergoeconomic factors (energy-economic factor, exergoeconomic factor, and cost of water), environmental impacts (CO2 emissions, exergo-environmental factor, and carbon credit gained), and sustainability indicators (energy payback time and sustainability index). Five different cases were examined: (I) a conventional solar still (CSS), (II) CSS with …


Drone Endurance In Hydrogen Fuel Cell Hybrid Technologies: Power Architectures And Design Strategies, Yaw Chong Tak, Tarek Abedin, Johnny Koh Siaw Paw, Jagadeesh Pasupuleti, Tan Jian Ding, Tiong Sieh Kiong, K. Kadirgama, F. Benedict, Mohammad Nur-E-Alam Jan 2026

Drone Endurance In Hydrogen Fuel Cell Hybrid Technologies: Power Architectures And Design Strategies, Yaw Chong Tak, Tarek Abedin, Johnny Koh Siaw Paw, Jagadeesh Pasupuleti, Tan Jian Ding, Tiong Sieh Kiong, K. Kadirgama, F. Benedict, Mohammad Nur-E-Alam

Research outputs 2022 to 2026

This study delivers an exhaustive exploration of novel and hybrid power systems for Unmanned Aerial Vehicles (UAVs) aimed at improving endurance, efficiency, and mission performance. In the wake of increasing requirements for long-endurance and high-performance UAVs, traditional battery systems are limited by their energy density and lifetime. To overcome this, the research compares four primary power sources: hydrogen fuel cells, lithium-based batteries, photovoltaic cells, and supercapacitors, with a focus on their hybrid architecture integration. The originality of this research is in the relative comparison of these power sources in multi-mode UAV operations, with an emphasis on their performance, energy management …


A Novel Hybrid Robust Transfer Learning-Based Adaptive Fractional-Order Super-Twisting Sliding Mode Controller Enhanced For Speed Regulation Of Brushless Dc Motor, Seyyed Morteza Ghamari, Asma Aziz, Daryoush Habibi Jan 2026

A Novel Hybrid Robust Transfer Learning-Based Adaptive Fractional-Order Super-Twisting Sliding Mode Controller Enhanced For Speed Regulation Of Brushless Dc Motor, Seyyed Morteza Ghamari, Asma Aziz, Daryoush Habibi

Research outputs 2022 to 2026

Brushless DC (BLDC) motors are widely used in applications that are highly-efficient, reliable, and compact, such as electric vehicles, robotics, and medical devices. However, the inherent nonlinearities and load sensitivity of BLDC motors require a robust and adaptive control strategy to ensure satisfactory performance under various operating conditions. Sliding mode control (SMC) has been widely used for the BLDC drives. However, because of its simplicity and robustness, the control effectiveness of the control is limited by the sensitivity to the disturbances and the chattering phenomenon. To remedy this, super-twisting (ST) technique has been proposed to achieve smoother response and better …


Age-Related Hearing Loss Involves Mitochondrial Dna Instability And Copy Number Depletion In The Cochlea: Insights From In Vivo And In Vitro Models, Akil Turner, Bo Ding, Xiaoxia Zhu, Tam Nguyen, Parveen Bazard, Robert D. Frisina Jan 2026

Age-Related Hearing Loss Involves Mitochondrial Dna Instability And Copy Number Depletion In The Cochlea: Insights From In Vivo And In Vitro Models, Akil Turner, Bo Ding, Xiaoxia Zhu, Tam Nguyen, Parveen Bazard, Robert D. Frisina

Chemical and Biochemical Engineering Faculty Research & Creative Works

Age-related hearing loss (ARHL) is a highly prevalent sensory neurodegenerative disorder that involves various molecular mechanisms. The present study investigated if age-related oxidative stress (OS) induces alterations in mitochondrial DNA (mtDNA) copy number and heteroplasmy, using complementary in vivo and in vitro models. Aged (30-month) CBA/CaJ mice have elevated auditory brainstem response (ABR) thresholds amplitudes vs. young (3-month) CBA/CaJ mice, a key physiological characteristic of ARHL The in vitro experiments employed the strial SV-K1 cochlear cell line treated with hydrogen peroxide (H2O2). Both the aged cochleae and H2O2-treated cells exhibited a significant …


Orchestrating Bone Healing: Biomaterial-Driven Immunoengineering Of The Bone Microenvironment For Advanced Regenerative Therapies, Ah Joung Rachel Yu, Mohammad Reza Zare, Edikan Ogunnaike, Mostafa Yazdi Jan 2026

Orchestrating Bone Healing: Biomaterial-Driven Immunoengineering Of The Bone Microenvironment For Advanced Regenerative Therapies, Ah Joung Rachel Yu, Mohammad Reza Zare, Edikan Ogunnaike, Mostafa Yazdi

Chemical and Biochemical Engineering Faculty Research & Creative Works

Bone regeneration is a multistage and tightly regulated process driven by coordinated interactions between the immune and skeletal systems. While inflammation is essential for initiating repair, its dysregulation contributes to delayed union, nonunion, and impaired healing commonly seen in trauma, chronic disease, and aging. Traditional interventions, including autografts and inert biomaterials, provide structural support but fail to engage or modulate the immune microenvironment that governs successful regeneration. Emerging research in osteoimmunology has revealed the centrality of immune cell populations such as macrophages, T regulatory cells, dendritic cells, and myeloid-derived suppressor cells in directing osteogenesis, angiogenesis, and the resolution of inflammation. …


Fracture Energy Of Ambient-Cured Fly Ash-Based Geopolymer Concrete, Alireza Mohyeddin, Trijon Karmokar, Mohammad Fardipour Jan 2026

Fracture Energy Of Ambient-Cured Fly Ash-Based Geopolymer Concrete, Alireza Mohyeddin, Trijon Karmokar, Mohammad Fardipour

Research outputs 2022 to 2026

Fracture energy is a key parameter in current prediction models for capacity of structural anchors. During broader research on behaviour of structural anchors in ambient-cured fly ash-based geopolymer concrete, it was realised that despite extensive literature on Ordinary Portland Cement (OPC) and other types of geopolymer concrete, there is a lack of literature on fracture energy of such geopolymer concretes. The purpose of the current research is to measure this property for this specific type of concrete using Wedge Splitting Test (WST) method. This method was selected due to its stable crack propagation and suitability for small-sized specimens. The influence …


Fill The Void - An Introductory Guide For Learning Medical Imaging, Reid Faith, Peter Gahan, Adam Trusty, Aleksandr Zyskin, Chukwuka Ukekwe, Denise Nchinda, Amanda K. Burbage, Alberto E. Musto Jan 2026

Fill The Void - An Introductory Guide For Learning Medical Imaging, Reid Faith, Peter Gahan, Adam Trusty, Aleksandr Zyskin, Chukwuka Ukekwe, Denise Nchinda, Amanda K. Burbage, Alberto E. Musto

EVMS School of Health Professions Faculty Publications

No standardized, comprehensive approach for radiological image interpretation exists among medical schools in the United States of America. In order to rectify this, we outline a model aimed to help improve how medical imaging can be taught in medical schools. The VOID (Visualization, Orientation/Observation, Identification, Description) guide is a proposed universal, stepwise approach to medical image identification, interpretation, and communication. This structured guideline is aimed at building a foundation for students in early medical education. The VOID was applied to CT (Computed Tomography), MRI (Magnetic Resonance Imaging), and x-ray modalities as integrated sessions for medical students during human anatomy laboratory. …


Implementation And Clinical Utility Of Ultra-Low-Field Portable Magnetic Resonance Imaging For Postprocedural Neurological Evaluation In Ambulatory Neurosurgery: Illustrative Cases, Devan Patel, Vinay Jaikumar, Taysia P. T. Morioka, Laz Rifkin, Kenneth S. Jacoby, Jaims Lim, Anais Andrade, Aimee C. Degaetano, Pui Man Rosalind Lai, Elad I. Levy Jan 2026

Implementation And Clinical Utility Of Ultra-Low-Field Portable Magnetic Resonance Imaging For Postprocedural Neurological Evaluation In Ambulatory Neurosurgery: Illustrative Cases, Devan Patel, Vinay Jaikumar, Taysia P. T. Morioka, Laz Rifkin, Kenneth S. Jacoby, Jaims Lim, Anais Andrade, Aimee C. Degaetano, Pui Man Rosalind Lai, Elad I. Levy

EVMS School of Health Professions Faculty Publications

BACKGROUND

Elective endovascular neurosurgical procedures are increasingly performed in ambulatory neurosurgery centers, enabled by advances in catheter technology, safety of conscious sedation, and refined patient selection. Although complication rates are low, rapid evaluation of postprocedural neurological deficits remains critical. Conventional MRI is often impractical in outpatient or procedural settings, whereas ultra-low-field portable MRI (ULF-pMRI) systems (such as Swoop) allow bedside imaging with favorable diagnostic performance.

OBSERVATIONS

Two women in their 60s developed acute neurological deficits at an ambulatory neurosurgery center (ANSC) after diagnostic cerebral angiography in one case and elective internal carotid artery flow diversion in the other. In both …


Automation And Autonomy In The Ivf Laboratory: Concepts And Implications For Embryologists, Jacques Cohen, Gerardo Mendizabal-Ruiz, Giles Anthony Palmer, Giuseppe Silvestri, Mina Alikani Jan 2026

Automation And Autonomy In The Ivf Laboratory: Concepts And Implications For Embryologists, Jacques Cohen, Gerardo Mendizabal-Ruiz, Giles Anthony Palmer, Giuseppe Silvestri, Mina Alikani

EVMS School of Health Professions Faculty Publications

Automation is regarded as the next phase in the evolution of laboratory IVF. Despite technological advances, most laboratory procedures remain operator-dependent, contributing to variability in performance and outcomes. While automation has improved reproducibility and efficiency in many areas of medicine, its adoption in IVF has been slow. This review examines how automation may be integrated into IVF laboratories through a set of conceptual distinctions. Automation refers to the execution of procedural steps by machine-controlled systems, whereas autonomy describes the degree to which such systems can operate without human intervention. This review distinguishes between static automation, which maintains or monitors the …


Additive Manufacturing And Heat Treatment Of Zero Poisson’S Ratio Self-Expanding Nitinol Stents, Farhana Yasmin, Vafadar, Majid Tolouei-Rad Jan 2026

Additive Manufacturing And Heat Treatment Of Zero Poisson’S Ratio Self-Expanding Nitinol Stents, Farhana Yasmin, Vafadar, Majid Tolouei-Rad

Research outputs 2022 to 2026

Additive manufacturing (AM) has recently gained attention as an effective approach for printing patient-specific, self-expanding Nitinol (NiTi alloy) stents with complex structural designs for the treatment of peripheral arterial disease (PAD). However, achieving the desired phase transformation temperature and superelastic performance remains challenging due to compositional variations, phase imbalance and microstructural inhomogeneities introduced during the printing process. In this study, self-expanding Nitinol stents with a zero Poisson’s ratio (ZPR) structural design were fabricated via laser powder bed fusion (PBF-LB). The printed stents showed no evidence of cracks or structural defects, confirming PBF-LB’s capability to produce mechanically sound stent geometries. However, …


Photocatalytic Degradation Of Cephalexin, Amoxicillin, And Phenol Red Using A Green-Synthesized Folic Acid–Zno–Bi2o3 Nanoporous System, M. Sarani, Haghighi, P. Tamaddon, A. Najafidoust, P. Faghani-Eskandarkolaei, N. Sattarahmady Jan 2026

Photocatalytic Degradation Of Cephalexin, Amoxicillin, And Phenol Red Using A Green-Synthesized Folic Acid–Zno–Bi2o3 Nanoporous System, M. Sarani, Haghighi, P. Tamaddon, A. Najafidoust, P. Faghani-Eskandarkolaei, N. Sattarahmady

Research outputs 2022 to 2026

The persistent presence of pharmaceutical pollutants like amoxicillin (AMX) and cephalexin (CPX), and industrial dyes such as phenol red (PR) in wastewater poses serious ecological and public health risks, including antibiotic resistance. It necessitates efficient and low-cost remediation technologies. Photocatalysts employing innovative and engineered nanomaterials such as bismuth oxide (Bi2O3) and zinc oxide (ZnO) nanostructures exhibit considerable potential for eliminating pollutants. This study focused on the photodegradation of AMX, CPX, and PR utilizing green-synthesized folic acid–ZnO–Bi2O3 nanoparticles (F-Zn-Bi NPs) under visible light irradiation. Characterization of the synthesized photocatalyst was conducted using various techniques of powder x-ray diffraction (PXRD), field emission …


Linker-Free Gold-Sputtered Tapered Optical Fiber Plasmonic Sensors For High-Sensitivity Refractive Index Detection In Microfluidic Platforms, Erem Ujah, Gymama Slaughter Jan 2026

Linker-Free Gold-Sputtered Tapered Optical Fiber Plasmonic Sensors For High-Sensitivity Refractive Index Detection In Microfluidic Platforms, Erem Ujah, Gymama Slaughter

Center for Bioelectronics Publications

Gold-sputtered tapered optical fiber (Au-TOF) sensors were developed for high-sensitivity refractive-index (RI) detection using aqueous glucose standards spanning 1.33–1.41 RIU (0–50% w/v). The sensors were fabricated using a reproducible workflow combining flame-brushing tapering, plasma surface preparation, and rotational magnetron sputtering, enabling azimuthally uniform gold coatings without the use of thiol or sulfur linker chemistries. Two sputtering durations (24 s and 30 s) were investigated to examine thickness-dependent plasmonic coupling and sensing performance. Optical measurements were conducted using a broadband supercontinuum source and compact spectrometer within a 20 µL microfluidic sensing chamber. Increasing glucose concentration produced a monotonic decrease in transmission …


Roadway Runoff Impacts To Trout Streams Studies For Ms4 Permit, Jobayed Hossain Badhan Jan 2026

Roadway Runoff Impacts To Trout Streams Studies For Ms4 Permit, Jobayed Hossain Badhan

College of Graduate Studies: Theses & Dissertations

Roadway runoff from Georgia Department of Transportation (GDOT) highway infrastructure poses measurable, but temporally constrained threats to cold-water trout ecosystems in northern Georgia. This study investigates temperature and dissolved oxygen (DO) dynamics in three secondary trout streams receiving GDOT roadway discharges, with the primary objective of evaluating compliance with Georgia Rule 391-3-6-.03(6)(ii),(v) under the Municipal Separate Storm Sewer System (MS4) permit framework. Field monitoring was conducted from April 2024 through October 2025 across two consecutive summer seasons using a tiered, multi-instrument approach: YSI ProDSS handheld grab sampling provided regulatory-grade reference measurements; HOBO MX-801 optical DO dataloggers recorded continuous 5-minute-interval temperature …


Solar Charging Chair, Joseph Austrian , ‘26, Jude Hemmins , ‘26, Neghemi Micah , ‘26 Jan 2026

Solar Charging Chair, Joseph Austrian , ‘26, Jude Hemmins , ‘26, Neghemi Micah , ‘26

Senior Theses, Projects, and Awards

For our E90 project, we constructed an outdoor Adirondack-style chair with a built-in battery and solar panel, so users can charge their devices while sitting outside. Through data collection and analysis, we were able to verify that our solar energy system, consisting of a 30W panel, 96Whr battery, MPPT charge controller, and DC-AC inverter, performs better than theoretically expected. The chair was built using pressure-treated lumber with the electrical components in a weatherproof box and solar panel attached to the back rest. The total cost was $667.15.


Yk-4-250, A Synthetic Telmisartan-Tempol Conjugate: Crystal Structure Of A Stabilized Free Radical Containing An Angiotensin At₁ Receptor Inhibitor, Simon Friedrich, Yali Kong, Faik N. Musayev, Milton L. Brown, B. Frank Gupton Jan 2026

Yk-4-250, A Synthetic Telmisartan-Tempol Conjugate: Crystal Structure Of A Stabilized Free Radical Containing An Angiotensin At₁ Receptor Inhibitor, Simon Friedrich, Yali Kong, Faik N. Musayev, Milton L. Brown, B. Frank Gupton

Department of Biomedical and Translational Sciences Faculty Publications

We report the first crystal structure of the telmisartan-tempol conjugate 2,2,6,6-tetramethyl-1-(λ'-oxidaneyl)piperidin-4-yl 4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl]-[1,1'-biphenyl]-2-carboxylate free radical (YK-4-250, C₄₂H₄₆N₅O₃), a dual-function inhibitor designed to target both the angiotensin II type 1 receptor (AT₁R) and reactive oxygen species (ROS). Structural analysis reveals a unique crystal architecture in which the nitroxide radical is stabilized within a sterically protected environment while preserving the telmisartan pharmacophore essential for high-affinity receptor antagonism. YK-4-250 is a novel small-molecule conjugate of telmisartan and tempol that incorporates a catalytic stabilized nitroxide radical and was rationally designed to mitigate gastrointestinal acute radiation syndrome (GI-ARS).


Process Optimization And Quality Control In Manufacturing Of Frp Composites By Vartm, Mohamed Emadeldin Omar Abdelhadi Jan 2026

Process Optimization And Quality Control In Manufacturing Of Frp Composites By Vartm, Mohamed Emadeldin Omar Abdelhadi

Graduate Theses, Dissertations, and Problem Reports (ETD)

Railroad tank cars, being one of the most used means of transportation of hazardous material across the country, have not been structurally upgraded for a long time. Thus, the Pipeline and Hazardous Materials Safety Administration (PHMSA), a United States Department of Transportation (USDOT) agency, released a rule for safer transportation of highly hazardous and flammable liquids by railroad to enhance the design specifications of both the new and existing tank cars in May 2015. A multifunctional composite jacket is proposed as a new material to structurally enhance the railroad tank cars to withstand any accidents that could happen en route. …


Bioprinted Scaffolds For Investigating Fibroblast Alignment, Lillian Thro, Daeha Joung Ph.D. Jan 2026

Bioprinted Scaffolds For Investigating Fibroblast Alignment, Lillian Thro, Daeha Joung Ph.D.

UROP Posters

Fibroblasts play a vital role in tissue repair, ECM remodeling, and maintaining structural integrity in human tissues. However, their behavior in engineered 3D microenvironments remains poorly understood. Traditional 2D cultures fail to capture the complex cell-cell and cell-matrix interactions that govern fibroblast alignment, migration, and proliferation in vivo. To address this gap, this project uses bioprinted scaffolds that mimic native ECM structures and provide a platform for studying fibroblast behavior in controlled microenvironments. The project focuses on varying scaffold channel properties—such as width, depth, and geometry—to investigate how physical cues influence fibroblast organization and collective migration. A biodegradable gelatin-based ECM …


Infrared Simulation, Sophia Zhou, Ashton Hoo, Tyler Ricks, Sebastian Fox, Kathy Phu Jan 2026

Infrared Simulation, Sophia Zhou, Ashton Hoo, Tyler Ricks, Sebastian Fox, Kathy Phu

UROP Posters

Infrared image recognition is more difficult than visible-spectrum recognition due to limited high-quality training data. This project addresses that challenge by generating simulated infrared images using temperature-driven rendering in Unreal Engine and other 3D software. These simulations can support applications such as health monitoring, heat detection in mechanical and structural systems, thermal regulation, and engineering process control.


Mapping Leo Satellite Internet Performance Using Mobile Starlink Deployment, Annika Govil, Jacob Gray Jan 2026

Mapping Leo Satellite Internet Performance Using Mobile Starlink Deployment, Annika Govil, Jacob Gray

UROP Posters

High-speed, low-latency internet connectivity on the move is a critical challenge for applications in connected vehicles, disaster response, and remote education. While terrestrial networks such as 4G or 5G are widespread, they lack coverage in remote or rural geographic areas.

Low Earth Orbit (LEO) satellite constellations, such as SpaceX's Starlink, promise global high-bandwidth, low-latency internet. However, their performance is well-documented in stationary scenarios, while data for *mobile* applications is scarce. This project explores the feasibility and real-world performance of LEO satellite internet while in motion.

Current research documents the performance of LEO satellite constellations in stationary settings. However, data concerning …


Using Nature-Inspired Sustainable Design Via Biomimicry Of The Peregrine Falcon To Improve The Development Of Japan’S F-X Fighter Jet, Tvisha Datta Jan 2026

Using Nature-Inspired Sustainable Design Via Biomimicry Of The Peregrine Falcon To Improve The Development Of Japan’S F-X Fighter Jet, Tvisha Datta

UROP Posters

Modern fighter jets face a persistent challenge when it comes to improving aerodynamic efficiency without having to sacrifice high-speed performance or long-term sustainability. These aircraft rely heavily on high thrust and agility, and in doing so, they consume substantial amounts of fuel due to aerodynamic drag and limited energy efficiency. As a result of these constraints, advanced military defense development projects, such as Japan’s Mitsubishi F-X fighter jet program, have been delayed. This highlights the need for more sustainable solutions. Biologically inspired design, or biomimicry, has emerged as a potential and promising alternative. The peregrine falcon, notably the fastest bird …