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Full-Text Articles in Engineering

Characterization, Performance, And Toxicological Assessment Of Polysulfone-Sulfonated Polyether Ether Ketone Membranes For Water Separation Applications, Muhammad Usman Yousaf, Lucca Madeo Cortarelli, Nerissa I. Jebet, Jason M. Unrine, Nirupam Aich, Olga V. Tsyusko, Isabel C. Escobar Mar 2025

Characterization, Performance, And Toxicological Assessment Of Polysulfone-Sulfonated Polyether Ether Ketone Membranes For Water Separation Applications, Muhammad Usman Yousaf, Lucca Madeo Cortarelli, Nerissa I. Jebet, Jason M. Unrine, Nirupam Aich, Olga V. Tsyusko, Isabel C. Escobar

Markey Cancer Center Faculty Publications

The removal of small molecular weight charged compounds from aqueous solutions using membrane remains a challenge. In this study, polysulfone (PSf)- and sulfonated polyether ether ketone (SPEEK)-based membranes were fabricated via non- solvent induced phase separation process (NIPS) using N-Methyl-2-Pyrrolidone (NMP) as solvent and water as non-solvent. Membranes were characterized structurally and morphologically, followed by toxicity assessment conducted before and after filtration, both with and without annealing at various pH values to evaluate potential leaching of trapped solvent from the membrane pores. Additionally, membrane performance was characterized using binary mixtures of cationic and anionic dyes. The results demonstrated selective filtration …


Overexpression And Biophysical And Functional Characterization Of A Recombinant Fgf21, Phuc Phan, Jason Hoang, Thallapuranam Krishnaswamy Suresh Kumar Mar 2025

Overexpression And Biophysical And Functional Characterization Of A Recombinant Fgf21, Phuc Phan, Jason Hoang, Thallapuranam Krishnaswamy Suresh Kumar

Chemistry & Biochemistry Faculty Publications and Presentations

Fibroblast growth factor 21 (FGF21) is an endocrine FGF that plays a vital role in regulating essential metabolic pathways. FGF21 increases glucose uptake by cells, promotes fatty acid oxidation, reduces blood glucose levels, and alleviates metabolic diseases. However, detailed studies on its stability and biophysical characteristics have not been reported. Herein, we present the overexpression, biophysical characterization, and metabolic activity of a soluble recombinant FGF21 (rFGF21). The far-UV circular dichroism spectra of rFGF21 show a negative trough at 215 nm, indicating that the protein’s backbone predominantly adopts a β sheet conformation. rFGF21 shows intrinsic tyrosine fluorescence at 305 nm. Thermal …


Unified Adaptive Cross-Attention Multimodal Network, Mahesh Sunuwar Mar 2025

Unified Adaptive Cross-Attention Multimodal Network, Mahesh Sunuwar

Shelby Hall Graduate Research Forum Posters

Accurately diagnosing appendicitis remains a significant challenge in emergency medicine due to its varied clinical presentation and overlap with other abdominal conditions. Existing diagnostic models often rely on unimodal data, such as computed tomography (CT) images or clinical notes, limiting their ability to capture the full complexity of patient information. This study proposes a novel multimodal framework, a Unified Adaptive Cross-Attention Multimodal Framework (u-ACM), that integrates CT images and clinical notes using hybrid fusion strategies to improve diagnostic accuracy for appendicitis. The u-ACM leverages adaptive contextual filtering to dynamically remove irrelevant features, crossattention mechanisms to align features between modalities, and …


02.24.2025 Ored Connect, Liz Williamson Feb 2025

02.24.2025 Ored Connect, Liz Williamson

ORED Newsletter

Collaborate Opportunity

SEC Faculty Travel Grants

Participant Support Cost Resources


02.17.2025 Ored Connect, Liz Williamson Feb 2025

02.17.2025 Ored Connect, Liz Williamson

ORED Newsletter

SOP Research Day


Anxiety Reduction In Autism Spectrum Disorder Using Novel Deep-Pressure Cutaneous Stimulation Therapy, Aaron Andrews, Jordyn Huecker, Kennedy Madrid, Lorissa Thorpe, James Fini, Josilyn Zamora, Victoria Oyeniyi, Maura Hart, Amanda Page, James Barber, Chase Taylor, Halah Khan, Spencer Willardson, Kyle Bills Phd, Christina Small Feb 2025

Anxiety Reduction In Autism Spectrum Disorder Using Novel Deep-Pressure Cutaneous Stimulation Therapy, Aaron Andrews, Jordyn Huecker, Kennedy Madrid, Lorissa Thorpe, James Fini, Josilyn Zamora, Victoria Oyeniyi, Maura Hart, Amanda Page, James Barber, Chase Taylor, Halah Khan, Spencer Willardson, Kyle Bills Phd, Christina Small

Annual Research Symposium

No abstract provided.


Identifying Breathing, Swallowing, And Speech Biosignatures In Parkinson’S Disease Patients With Wearable Devices, Amanda Brandaris, Katherine Shishido, Rohaan Manzoor, Ethan Hampton, Karthik Jasty, Kelvin Guo, Anna Fish, Spencer Peterson, Ulrike H. Mitchell Phd, Phillip Sechtem Phd, Ccc-Slp, Paula Johnson Phd, Anton E. Bowden Phd, Miriam Cortez-Cooper Pt, Phd, Pamela I. Barney Msrt, Rrt, Ae-C, Nps, John A. Kriak Pharmd Feb 2025

Identifying Breathing, Swallowing, And Speech Biosignatures In Parkinson’S Disease Patients With Wearable Devices, Amanda Brandaris, Katherine Shishido, Rohaan Manzoor, Ethan Hampton, Karthik Jasty, Kelvin Guo, Anna Fish, Spencer Peterson, Ulrike H. Mitchell Phd, Phillip Sechtem Phd, Ccc-Slp, Paula Johnson Phd, Anton E. Bowden Phd, Miriam Cortez-Cooper Pt, Phd, Pamela I. Barney Msrt, Rrt, Ae-C, Nps, John A. Kriak Pharmd

Annual Research Symposium

No abstract provided.


02.10.2025 Ored Connect, Liz Williamson Feb 2025

02.10.2025 Ored Connect, Liz Williamson

ORED Newsletter

Community Engagement Recognition


Machine Learning And Shap Interpretability For Chronic Disease Understanding, Nnaemeka Charles Igwe, Khandaker Mamun Ahmed Feb 2025

Machine Learning And Shap Interpretability For Chronic Disease Understanding, Nnaemeka Charles Igwe, Khandaker Mamun Ahmed

SDSU Data Science Symposium

Non-communicable diseases (NCDs), such as diabetes, are major global health concerns influenced by various health parameters and lifestyle choices. Traditional methods struggle to efficiently predict and manage these conditions due to the complexity and diversity of medical data. There is a need to leverage machine learning algorithms and modern computational tools to accurately predict diabetes, improve diagnosis, and provide actionable insights for better healthcare outcomes. In this project we study the application of machine learning methods for predicting NCDs such as diabetes. Moreover, we leverage hyperparameter tuning techniques for model development and SHapley Additive exPlanation (SHAP) for results interpretations and …


Inclusive Space For Everyone Door Sign (Printable 8.5 X 11 Inch), Joan H. Robinson Feb 2025

Inclusive Space For Everyone Door Sign (Printable 8.5 X 11 Inch), Joan H. Robinson

Open Educational Resources

This is a printable 8.5 x 11 inch door sign for faculty, staff, and administrators to let people know it is an inclusive space for everyone. For improved visibility, print with a color printer and cut along the dotted line.

See also: 11 x 17 inch door sign.


01.27.2025 Ored Connect, Liz Williamson Jan 2025

01.27.2025 Ored Connect, Liz Williamson

ORED Newsletter

Data Science for Addiction Research

UM research and related activities as a new presidential administration transition occurs


01.21.2025 Ored Connect, Liz Williamson Jan 2025

01.21.2025 Ored Connect, Liz Williamson

ORED Newsletter

SmartTech MS Advanced Manufacturing Prize

Mileage Rate Increases

Meth Mortality Rate Increases


Feasibility And Acceptability Of The Mazi Umntanakho Digital Tool In South African Settings: A Qualitative Evaluation, Catherine E. Draper, Caylee J. Cook, Elizabeth A. Ankrah, Jesus A. Beltran, Franceli L. Cibrian, Kimberley D. Lakes, Hanna Mofid, Lucretia Williams, Gillian R. Hayes Jan 2025

Feasibility And Acceptability Of The Mazi Umntanakho Digital Tool In South African Settings: A Qualitative Evaluation, Catherine E. Draper, Caylee J. Cook, Elizabeth A. Ankrah, Jesus A. Beltran, Franceli L. Cibrian, Kimberley D. Lakes, Hanna Mofid, Lucretia Williams, Gillian R. Hayes

Engineering Faculty Articles and Research

To address the need for interventions targeting social emotional development and mental health of young children in South Africa, the Mazi Umntanakho (‘know your child’) digital tool was co-designed, and piloted with caregivers and 3–5-year-old children involved in home visiting programmes promoting early childhood development. The aim of this study was to qualitatively evaluate the feasibility and acceptability of this tool in four urban and four rural low-income communities, from the perspective of home visitors and caregivers. Focus groups were conducted with home visitors (n = 117) and caregivers (n = 72). Issues relating to the feasibility of …


One Heart, One Vessel: Unraveling The Mystery Of Truncus Arteriosus, Claudette C. Artiles Jan 2025

One Heart, One Vessel: Unraveling The Mystery Of Truncus Arteriosus, Claudette C. Artiles

Mako: NSU Undergraduate Student Journal

No abstract provided.


What’S New In Esophageal Atresia Treatment?, Alexandra N. Jimenez Gonzalez Jan 2025

What’S New In Esophageal Atresia Treatment?, Alexandra N. Jimenez Gonzalez

Mako: NSU Undergraduate Student Journal

No abstract provided.


Associations Between Social Determinants Of Health And Mental Health Disorders Among U.S. Population: A Cross-Sectional Study, S. Tanarsuwongkul Jan 2025

Associations Between Social Determinants Of Health And Mental Health Disorders Among U.S. Population: A Cross-Sectional Study, S. Tanarsuwongkul

Faculty Publications

Aims

The impact of social determinants of health (SDOH) on mental health is increasingly realized. A comprehensive study examining the associations of SDOH with mental health disorders has yet to be accomplished. This study evaluated the associations between five domains of SDOH and the SDOH summary score and mental health disorders in the United States.

Methods

We analyzed data from a diverse group of participants enrolled in the All of Us research programme, a research programme to gather data from one million people living in the United States, in a cross-sectional design. The primary exposure was SDOH based on Healthy …


Advancing Prosthetic Technology: 3d-Printed Robotic Arm With Micro Linear Actuators, Vu Tran, Nathan Reed, Mahdi Yazdanpour Jan 2025

Advancing Prosthetic Technology: 3d-Printed Robotic Arm With Micro Linear Actuators, Vu Tran, Nathan Reed, Mahdi Yazdanpour

Posters-at-the-Capitol

The increasing demand for affordable and accessible prosthetic solutions has driven innovation in the field of robotics. In this project, we present the design and development of a 3D-printed robotic prosthetic arm aimed at addressing the challenges faced by individuals with upper limb amputations. Our prosthetic arm utilizes five micro linear actuators to achieve precise and naturalistic movement. The design of the prosthetic arm prioritizes affordability and accessibility, with a focus on leveraging 3D printing technology to reduce manufacturing costs and enable customization. The use of micro linear actuators offers advantages in terms of compactness, lightweight construction, and efficient power …


01.13.2025 Ored Connect, Liz Williamson Jan 2025

01.13.2025 Ored Connect, Liz Williamson

ORED Newsletter

NIH Public Access Policy Update

Procurement Information for Award Spending online course announcement

National Sea Grant Law Center funding


Evaluating Lidar Technology In Iphone Mobiles For 2d Mapping Applications, Nasr Mohammady Saba, Salem Salama Saleh Jan 2025

Evaluating Lidar Technology In Iphone Mobiles For 2d Mapping Applications, Nasr Mohammady Saba, Salem Salama Saleh

Journal of Engineering Research

Abstract- LiDAR (Light Detection and Ranging) technology has revolutionized mapping applications, offering enhanced precision and accuracy in spatial data collection. The integration of LiDAR technology in the latest iPhone models, beginning with the iPhone 12 Pro, has introduced new capabilities for 2D data measurement and plan creation directly on the mobile device. The iPhone 12 Pro and 12 Pro Max models support LiDAR techniques within their mobile phone cameras, enhancing the performance of various applications such as Measurements and Photos. LiDAR operates by emitting pulsed light waves into the surrounding space, which bounce off nearby objects and return to the …


Experimental And Numerical Investigation For Optimum Design Of Hydraulic Steel Gates, Basma Hassan Mohamed Eng, Ahmed Mohamed Anwer Dr, Hanan Eltobgy Prof., Gamal Helmy El-Saeed Prof Jan 2025

Experimental And Numerical Investigation For Optimum Design Of Hydraulic Steel Gates, Basma Hassan Mohamed Eng, Ahmed Mohamed Anwer Dr, Hanan Eltobgy Prof., Gamal Helmy El-Saeed Prof

Journal of Engineering Research

Conventionally, steel gates are widely used in hydraulic structures for their superior mechanical properties in sustaining hydrostatic pressure. Maintenance and operational costs should be considered while studying the feasibility of these gates. In the current research, three prototype steel gates with different configurations were prepared and examined experimentally. The three gates have the same surface dimensions of (width x height) equal to (1.0 x 1.25 m). The first steel gate represents a typical traditional gate made of skin plate and stiffened laterally using standard steel channels and will be kept for comparison. The second gate represents a standard thicker plate …


Performance And Emissions Characteristics Of Multi-Cylinder Direct Injection Diesel Engine Fuelled With Diesel/Biodiesel And Toluene Additives, Hagar Alm-Eldin Bastawissi, Medhat Elkelawy Prof. Dr. Eng., Mohammed Osama Elsamadony Dr. Eng., Moustafa Ghazaly Eng. Jan 2025

Performance And Emissions Characteristics Of Multi-Cylinder Direct Injection Diesel Engine Fuelled With Diesel/Biodiesel And Toluene Additives, Hagar Alm-Eldin Bastawissi, Medhat Elkelawy Prof. Dr. Eng., Mohammed Osama Elsamadony Dr. Eng., Moustafa Ghazaly Eng.

Journal of Engineering Research

This study explores the impact of using a diesel, biodiesel, and toluene additive fuel blend in a multi-cylinder direct injection diesel engine, focusing on both performance and emissions characteristics. Biodiesel, made from renewable sources like vegetable oils, is often added to diesel to reduce reliance on fossil fuels and improve combustion due to its higher oxygen content. In this work, a 45% biodiesel blend (B45) led to significant reductions in particulate matter (PM) emissions by up to 40% compared to conventional diesel. Additionally, carbon monoxide (CO) and hydrocarbon (HC) emissions decreased by up to 30% and 25%, respectively, due to …


Effect Of Dual-Fuelled Cng And Gasoline On Spark Ignition Engine Performance And Emissions Behaviors At Different Loads, Medhat Elkelawy Prof. Dr, Eng., M.M. Bassuoni Prof. Dr., Hagar Alm-Eldin Bastawissi, Saied I. Haiba Eng. Jan 2025

Effect Of Dual-Fuelled Cng And Gasoline On Spark Ignition Engine Performance And Emissions Behaviors At Different Loads, Medhat Elkelawy Prof. Dr, Eng., M.M. Bassuoni Prof. Dr., Hagar Alm-Eldin Bastawissi, Saied I. Haiba Eng.

Journal of Engineering Research

Engine emissions are one of numerous factors that have detrimentally affected the environment, such as global warming, which is the result of growing exhaust gases, practically carbon dioxide (CO2). These emissions have substantially influenced researchers to develop strategic initiatives to minimize the carbon contents of fuels. The purpose of this research is to investigate the characteristics of internal combustion (SI) engines fueled by gasoline and compressed natural gas (CNG) blends. The experiments are performed using a HONDA 4-stroke, single-cylinder, and air-cooled SI engine. Five CNG concentrations are evaluated, the concentrations range from 0.5 to 2.5 L/min with a 0.5 L/min …


A Quantitative Analysis Of The Commercial-Additive Effects On Diesel Engine Combustion And Emissions Characteristics, Medhat Elkelawy Prof. Dr. Eng., Hagar Alm-Eldin Bastawissi Prof. Dr. Eng., E. A. El Shenawy Prof. Dr., Mahmoud Mohamed Soliman Mahmoud Mohamed Mahmoud Soliman Jan 2025

A Quantitative Analysis Of The Commercial-Additive Effects On Diesel Engine Combustion And Emissions Characteristics, Medhat Elkelawy Prof. Dr. Eng., Hagar Alm-Eldin Bastawissi Prof. Dr. Eng., E. A. El Shenawy Prof. Dr., Mahmoud Mohamed Soliman Mahmoud Mohamed Mahmoud Soliman

Journal of Engineering Research

Petroleum fuel prices fluctuate in response to global political and economic issues. Government regulations should be followed when it comes to engine emissions, as these dangerous pollutants have a negative impact on the environment. One such effect is global warming, which raises global temperatures. The purpose of this study is to develop the additives for use as a fuel mix with diesel fuel, which will be used to feed the diesel engine of a single cylinder, four strokes. The engine will be tested experimentally with varying loads at fixed speed of 1500 rpm, using blends of [(5% PRETSONE additive + …


Design And Implementation Of A Low-Cost Educa-Tional Robot For Engineering Curriculums, Diana Refaat Henry Jacob, Ashraf Mohamed Hafez, Mohamed Tarek Elawa Jan 2025

Design And Implementation Of A Low-Cost Educa-Tional Robot For Engineering Curriculums, Diana Refaat Henry Jacob, Ashraf Mohamed Hafez, Mohamed Tarek Elawa

Journal of Engineering Research

The role of educational robots is becoming increasingly important. Many commercial educational robots differ in their abilities and price. In general, the cost of these robots presents the main cause of their limited use in the teaching process, especially in countries with limited financial resources. This work attempts to solve this problem by designing and implementing an educational robot with a limited budget. The robot was initially intended to serve higher education students' needs, especially in engineering curriculums but can be extended to other application areas. This work presents robot hardware functional blocks, mechanical struc-ture design, and 3D printing implementation. …


A Greening The Diesel: Vegetable Oil Biodiesel Blends For Cleaner Emissions And Improved Direct Injection Diesel Engine Performance, Medhat Elkelawy Prof. Dr, Eng., Hagar Alm-Eldin Bastawissi, E. A. El Shenawy Prof. Dr., Mustafa Mohamed Ouda Jan 2025

A Greening The Diesel: Vegetable Oil Biodiesel Blends For Cleaner Emissions And Improved Direct Injection Diesel Engine Performance, Medhat Elkelawy Prof. Dr, Eng., Hagar Alm-Eldin Bastawissi, E. A. El Shenawy Prof. Dr., Mustafa Mohamed Ouda

Journal of Engineering Research

In this study, we conducted comprehensive experiments to assess and compare the performance of pure diesel fuel against biodiesel produced from corn oil in various blend ratios (15/85, 30/70, 45/55, and 60/40) in a conventional four-stroke, direct-injection diesel engine, fuel is injected directly into the combustion chamber at the end of the compression stroke, allowing for efficient combustion and power generation over four distinct phases: intake, compression, power, and exhaust. Each fuel blend was tested at an engine speed of 16,000 rpm across different load conditions (low, medium, and high). Key performance metrics, including volumetric fuel consumption, exhaust smoke, and …


A Survey On Food Ingredient Substitutions, Hyunwook Kim, Revathy Venkataramanan, Amit P. Sheth Jan 2025

A Survey On Food Ingredient Substitutions, Hyunwook Kim, Revathy Venkataramanan, Amit P. Sheth

Publications

Diet plays a crucial role in managing chronic conditions and overall well-being. As people become more selective about their food choices, finding recipes that meet dietary needs is important. Ingredient substitution is key to adapting recipes for dietary restrictions, allergies, and availability constraints. However, identifying suitable substitutions is challenging as it requires analyzing the flavor, functionality, and health suitability of ingredients. With the advancement of AI, researchers have explored computational approaches to address ingredient substitution. This survey paper provides a comprehensive overview of the research in this area, focusing on five key aspects: (i) datasets and data sources used to …


Reduced Set-Shifting Processing Speed In Male Rats Following Low Dose (10 Cgy) Proton Exposure, Hui Ho Vanessa Chang, Gyutae Kim, Kyu-Sung Kim, Richard A. Britten Jan 2025

Reduced Set-Shifting Processing Speed In Male Rats Following Low Dose (10 Cgy) Proton Exposure, Hui Ho Vanessa Chang, Gyutae Kim, Kyu-Sung Kim, Richard A. Britten

Center for Integrative Neuroscience and Inflammatory Diseases (CINID) Faculty Publications

Space radiation (SR) exposure poses significant biomedical risks, including effects on the central nervous system (CNS). These risks are particularly relevant to cognitive function during long-duration space missions. One critical cognitive skill is decision-making, which requires attentional set-shifting (ATSET)—the ability to quickly assess problems, evaluate options, and select the best actions. Previous studies have shown that exposure to However, the impact of low LET (< 1 keV/μm) protons, which significantly contribute to the total radiation flux astronauts encounter within spacecraft, on ATSET performance is unknown. To address this gap, we evaluated the effects of cranial irradiation with 10 cGy of 100 MeV/n protons (LET = 0.732 keV/μm) on ATSET performance in male Sprague-Dawley rats. We also investigated whether concurrent exposure to variable gravity (hypergravity step-up, step down, purported to have the same effect as exposure to microgravity (another major spaceflight stressor) exacerbated SR-induced cognitive deficits. Our findings indicate that proton exposure alone significantly impaired ATSET performance, as evidenced by decreased processing speed while performing compound discrimination reversal and extra-dimensional shifting. Notably, no additive or synergistic effects were observed when hypergravity was combined with proton exposure. The impact that low-dose proton exposure has on CNS functionality, particularly in reducing processing speed during complex tasks, warrant further investigation. If similar cognitive deficits were to occur in astronauts exposed to galactic cosmic rays, mission success and safety could be significantly compromised.


Novel Electrophysiological Biomarkers In Pediatric Drug Resistant Epilepsy And Genetic Epilepsy Syndromes, Sakar Rijal Jan 2025

Novel Electrophysiological Biomarkers In Pediatric Drug Resistant Epilepsy And Genetic Epilepsy Syndromes, Sakar Rijal

Bioengineering Dissertations - Archive

Pediatric epilepsies, particularly those that are drug-resistant or genetically driven, represent some of the most complex neurological disorders encountered in childhood. Central to their pathophysiology is a disruption in the delicate balance between cortical excitation and inhibition (E/I), often resulting from impaired GABAergic interneuron function. This imbalance manifests as aberrant network dynamics and altered neural oscillations, giving rise to seizures and long-term cognitive impairments. In this thesis, we developed a translational framework to identify electrophysiological biomarkers that (i) assess cortical E/I imbalance and (ii) map epileptogenic zones, with the aim of enhancing diagnosis, guiding surgical planning, and informing therapeutic monitoring …


Exploring Large Language Models For Summarizing And Interpreting An Online Brain Tumor Support Forum, Christy Muasher-Kerwin, M. Courtney Hughes, Michelle L. Foster, Ibrahiim Al Azher, Hamed Alhoori Jan 2025

Exploring Large Language Models For Summarizing And Interpreting An Online Brain Tumor Support Forum, Christy Muasher-Kerwin, M. Courtney Hughes, Michelle L. Foster, Ibrahiim Al Azher, Hamed Alhoori

Faculty Articles, Papers, and Other Scholarship

Objective

This study explored the capabilities of large language models (LLMs) GPT-3.5, GPT-4, and Llama 3 to summarize qualitative data from an online brain tumor support forum, assessing the differences between these methods and traditional thematic analysis.

Methods

Eight posts and responses were collected in September 2024 from the American Brain Tumor Association Brain Tumor Support Group, using the passive/unobtrusive method. The data were analyzed using two methods: (1) traditional thematic coding with Dedoose software and (2) summarization and interpretation using LLMs. Prompts guided the LLMs in generating summaries and identifying key challenges, with results evaluated using the metrics BLEU, …


Quantifying Multidimensional Effects Of Physicochemical Parameters On Pfas Adsorption Using A Hybrid Response Surface Methodology-Machine Learning Approach, Harsh V. Patel, Jazmin Green, John Park, Stephanie Luster-Teasley Pass, Renzun Zhao Jan 2025

Quantifying Multidimensional Effects Of Physicochemical Parameters On Pfas Adsorption Using A Hybrid Response Surface Methodology-Machine Learning Approach, Harsh V. Patel, Jazmin Green, John Park, Stephanie Luster-Teasley Pass, Renzun Zhao

Engineering Management & Systems Engineering Faculty Publications

Per- and polyfluoroalkyl substances (PFAS) contamination has posed a significant environmental and public health challenge due to their ubiquitous nature. Adsorption has emerged as a promising remediation technique, yet optimizing adsorption efficiency remains complex due to the diverse physicochemical properties of PFAS and the wide range of adsorbent materials. Traditional modeling approaches, such as response surface methodology (RSM), struggled to capture nonlinear interactions, while standalone machine learning (ML) models required extensive datasets. This study addressed these limitations by developing hybrid RSM-ML models to improve the prediction and optimization of PFAS adsorption. A comprehensive dataset was constructed using experimental adsorption data, …