Engineering Commons^™

The Migrant Crisis At The U.S. Southern Border, Matthew Ingber, Conner Muth, Nathanael Hall

Immigration Scholarship: History, Trends and Development in Global Immigration

The immigration policy of The United States of America is a divisive topic within American society. There is no doubt that this policy needs reform. This paper will investigate the ways in which The U.S. immigration policy at the Southern border negatively impacts those seeking asylum and will conclude with suggested policy changes that would potentially have the greatest positive impact on these individuals. Ever since 2016 media outlets have declared war on people crossing the southern border illegally. Media giants such as Fox News have repeatedly grouped those individuals within the same constructs as rapists, gang members, drug smugglers, …

Development Of A Decellularized Hydrogel Composite And Its Application In A Novel Model Of Disc-Associated Low Back Pain In Female Sprague Dawley Rats, David Lillyman

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

Chronic low back pain is a global socioeconomic crisis compounded by an absence of reliable, curative treatments. The predominant pathology associated with chronic low back pain is degeneration of intervertebral discs in the lumbar spine. During degeneration, nerves can sprout into the intervertebral disc tissue and be chronically subjected to inflammatory and mechanical stimuli, resulting in pain. Pain arising from the intervertebral disc, or disc-associated pain, is a complex, multi-faceted disorder which necessitates valid animal models to screen therapeutics and study pathomechanisms of pain.

While many research teams have created animal models of disc degeneration, the translation of these platforms …

Stratospheric Effects On Uv, Speed Of Sound, Pressure, And Temperature, Joshua V. Chis, Joana Diaz, Brianna E. Ortiz, Imani G. Robertson, Jelani A. Shadd

DePaul Discoveries

The atmosphere is composed of several layers, each with its own distinct environment varying in temperature, pressure, and levels of UV radiation. Quantifying these varying parameters proves to be useful in understanding atmospheric composition in greater detail. Variance in the composition of the atmosphere allows for the study of the evolution of physical phenomena at different altitudes. Our group quantified this variance using a high-altitude weather balloon and designed an experimental method to observe the nature of sound propagation through varying altitudes. The goal was to develop an altitude-dependent model of the speed of sound by using an open-air, microcontroller-based …

Failure Detection In Deep Neural Networks For Medical Imaging, Sabeen Ahmed, Dimah Dera, Saud Ul Hassan, Nidhal Bouaynaya, Ghulam Rasool

Electrical and Computer Engineering Faculty Publications

Deep neural networks (DNNs) have started to find their role in the modern healthcare system. DNNs are being developed for diagnosis, prognosis, treatment planning, and outcome prediction for various diseases. With the increasing number of applications of DNNs in modern healthcare, their trustworthiness and reliability are becoming increasingly important. An essential aspect of trustworthiness is detecting the performance degradation and failure of deployed DNNs in medical settings. The softmax output values produced by DNNs are not a calibrated measure of model confidence. Softmax probability numbers are generally higher than the actual model confidence. The model confidence-accuracy gap further increases for …

Classifying Toe Walking Gait Patterns Among Children Diagnosed With Idiopathic Toe Walking Using Wearable Sensors And Machine Learning Algorithms, Rahul Soangra, Yuxin Wen, Hualin Yang, Marybeth Grant-Beuttler

Physical Therapy Faculty Articles and Research

Idiopathic toe walking (ITW) is a gait abnormality in which children’s toes touch at initial contact and demonstrate limited or no heel contact throughout the gait cycle. Toe walking results in poor balance, increased risk of falling, and developmental delays among children. Identifying toe walking steps during walking can facilitate targeted intervention among children diagnosed with ITW. With recent advances in wearable sensing, communication technologies, and machine learning, new avenues of managing toe walking behavior among children are feasible. In this study, we investigate the capabilities of Machine Learning (ML) algorithms in identifying initial foot contact (heel strike versus toe …

Cellular Mechanisms Underlying State-Dependent Neural Inhibition With Magnetic Stimulation, Hui Ye, Vincent Chiun-Fan Chen, Jenna Hendee

Engineering Science Faculty Publications

Novel stimulation protocols for neuromodulation with magnetic fields are explored in clinical and laboratory settings. Recent evidence suggests that the activation state of the nervous system plays a significant role in the outcome of magnetic stimulation, but the underlying cellular and molecular mechanisms of state-dependency have not been completely investigated. We recently reported that high frequency magnetic stimulation could inhibit neural activity when the neuron was in a low active state. In this paper, we investigate state-dependent neural modulation by applying a magnetic field to single neurons, using the novel micro-coil technology. High frequency magnetic stimulation suppressed single neuron activity …

Development Of A Programmable, Open-Source, And Cost-Effective Fluidic System For Cell Culture Applications, Charles Montoya

Biomedical Engineering ETDs

Open-source laboratory equipment has become an increasingly popular alternative to commercially available options due to its simple implementation, capability of user-customized modifications, and cost-effectiveness. Presented here is the development of a programmable and open-source fluidic system comprised of three custom-built syringe pumps for cell culture applications. The fluidic system was directly integrated with a multiwell plate on an environmentally controlled microscope platform for live-cell imaging and time-lapse analyses of cellular responses as culture conditions are adjusted using the programmable fluidic system. Proof-of-concept of this system is obtained by controlling autophagic activity in A549 cells by adjustment of nutrient supply. The …

Combination Of Statistical Shape Modeling And Statistical Parametric Mapping To Quantify Cartilage Contact Mechanics In Hip Dysplasia, Penny R. Atkins Phd, Shireen Y. Elhabian Phd, Jeffrey A. Weiss Phd, Ross T. Whitaker Phd, Christopher L. Peters Md, Andrew E. Anderson Phd

PanaSoMM

Finite element models can predict subject-specific chondrolabral stresses and help to elucidate the effect of under-coverage and incongruency of the hip joint in patients with dysplasia. However, complex stress patterns are difficult to generalize and evaluate statistically. With an established correspondence across shapes from statistical shape modeling (SSM), statistical parametric mapping (SPM) allows for evaluation of local variability while preserving model subject-specificity. Herein, we evaluated the combined application of SSM and SPM to compare cartilage contact stress between control subjects and patients with dysplasia.

Previously published hip joint contact stresses were mapped onto chondrolabral surface meshes and incorporated into an …

Application Of Statistical Shape Modeling To Predict Clinical Metric Of Femoral Head Coverage In Patients With Developmental Dysplasia, Penny R. Atkins Phd, Praful Agrawal Phd, Joseph D. Mozingo Phd, Keisuke Uemura Md, Phd, Kunihiko Tokunaga Md, Christopher L. Peters Md, Shireen Y. Elhabian Phd, Ross T. Whitaker Phd, Andrew E. Anderson Phd

PanaSoMM

Developmental dysplasia of the hip (DDH) is described as under-coverage of the femoral head by the acetabulum, resulting in mechanical instability. Though DDH is often diagnosed using plain film radiographs, these images cannot adequately capture 3D joint coverage. Herein, we applied a 3D statistical shape model (SSM) to the femur and hemi-pelvis of patients with DDH to objectively measure shape variation and evaluated whether SSM outputs could predict measurements of joint coverage.

The femur and hemi-pelvis were semi-automatically segmented from CT images (83 hips from 47 females with DDH). Surfaces of each hip were reconstructed from segmentations, aligned, and input …

Pulsatility Is A Predictive Marker Of Improved Cardiac Function In Patients With Liquid Matrix-Treated Left Ventricular Assist Devices, Philemon Mikail, Rinku Skaria, Marvin Slepian, Janny Garcia, Richard Smith, Zain Khalpey

The VAD Journal

Objective: Left ventricular assist devices (LVADs) are utilized as a bridge to transplant or as destination therapy for patients with end-stage heart failure. Although cardiac offloading from these devices rarely leads to complete remodeling and functional recovery, the use of mesenchymal cells to modulate heart failure has been explored in recent years due to its intrinsic regenerative properties. Current methods of evaluating cardiac function have too much variability, difficulty of access, or require too frequent follow up to create universal weaning protocols. We hypothesized that the administration of amniotic allograft liquid matrix (LM) containing amnion-derived mesenchymal stem cells (aMSCs) in …

Santa Clara Magazine, Volume 63 Number 1, Summer 2022, Santa Clara University

Santa Clara Magazine

16 - SHARED DREAMS Meet incoming University President Julie Sullivan, the first layperson and woman selected to lead SCU. Leslie Griffy

20 - BD KNOWS BEST Discovering who you really are, being grateful, and dinosaurs with BD Wong. Lauren Loftus.

22 - SWEPT AWAY Being homeless in Silicon Valley is particularly deadly. One professor explores why so many die in a land of such excess. Leslie Griffy .

28 - ON THE OUTSIDE A first-person account of being wrongly convicted, as told by Arturo Jimenez.

30 - BOOKED AND BUSY The secret behind the Hollywood success of so many Bronco …

A Patient Risk Minimization Model For Post-Disaster Medical Delivery Using Unmanned Aircraft Systems, Mark J. Simpson

Doctoral Dissertations and Master's Theses

The purpose of this research was to develop a novel routing model for delivery of medical supplies using unmanned aircraft systems, improving existing vehicle routing models by using patient risk as the primary minimization variable.

The vehicle routing problem is a subset of operational research that utilizes mathematical models to identify the most efficient route between sets of points. Routing studies using unmanned aircraft systems frequently minimize time, distance, or cost as the primary objective and are powerful decision-making tools for routine delivery operations. However, the fields of emergency triage and disaster response are focused on identifying patient injury severity …

Effect Of Injury Mechanism And Severity On The Molecular Pathophysiology Of Traumatic Brain Injury, Brandon Mcdonald

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

Traumatic brain injury (TBI) mechanism and severity are heterogenous clinically, resulting in a multitude of physical, cognitive, and behavioral deficits. However, approximately 80% suffer from milder injuries. Thus, examining pathophysiological changes associated with mild TBI is imperative for improving clinical translation and evaluating the efficacy of potential therapeutic strategies. Through this work, we developed models of TBI, ranging in both injury mechanism and severity, using an electromagnetic controlled cortical impact (CCI) device. First, we characterized and optimized a closed head, mild TBI model (DTBI) to determine the clinical translatability and practicality of producing repeated mild injuries. Interestingly, we determined that …

Behavioral Intention Factors For Prescription Deliveries By Small Unmanned Aircraft In Rural Communities, Sarah M. Talley

Doctoral Dissertations and Master's Theses

Nearly half of the U.S. population regularly use and depend on prescription medications; however, pharmacy availability and access to pharmacy services are often lacking, particularly in rural communities. In an effort to meet local healthcare needs, delivery by sUAS is proposed to ensure the nearly 60 million rural residents have access to their prescription medications.

As an emerging technology with little research into home delivery applications, the successful implementation of sUAS for prescription medication delivery requires public acceptance and positive behavioral intention toward its use. At the time of the current research, no prior studies have specifically focused on the …

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.

A Convergent Approach To Aqueous Lead (Pb) Mitigation Of A Supplemental Self-Supply Shallow Groundwater Source Accessed By Handpumps In Madagascar, Adaline Marie Buerck

USF Tampa Graduate Theses and Dissertations

The World Health Organization (WHO) has consistently listed lead (Pb) as one of the ten chemicals of major public health concern. Though the toxic nature of lead has been known since the 20th century it is still utilized in a wide variety of products due to its favorable properties. Exposure to lead still accounts for approximately 900,000 deaths annually and disproportionately impacts those in low- and middle-income countries (LMIC) due to a variety of reasons such as poverty, malnutrition, and lack of knowledge on the toxic nature of lead. Lead exposure routes include air, soil, dust, diet, and water. Though …

Student Self-Grading Form, Brett Whysel

Open Educational Resources

This is a word document that students use at the beginning, midpoint, and end of a semester to set relevant goals, measure progress towards goals, and self-grade. It is intended to build motivation, metacognition, and accountability. Instructors may use it on its own or to supplement other assessment tools, and improve the accuracy, validity, and fairness of final grades.

A Simplified Model For The Intermediate Structure Of Strong Fire Whirls, Forman A. Williams

Progress in Scale Modeling, an International Journal

A model is described for the overall structure of intense fire whirls, based on a spatially evolving vortex, with circulation enhancement driven by the axial acceleration of low-density gas in the core through the axial pressure gradient. The axial acceleration increases the entrainment rate into the core which, through mass conservation, increases the circulation if the angle between the tangential and radial velocity components remains fixed. The two-zone model employs general balance equations for regions inside and outside a cylinder of fixed radius, each inviscid, the inside region being presumed to have a constant density small compared with the (constant) …

Cardio-Net: A Matlab-Based Software For The Display And Diagnostic Utilization Of Vectorcardiograms, Ali H. Mannaa, Domenico Gatti

Medical Student Research Symposium

Background: The 12-lead technique is the standard in ECG, however alternate cardiography modalities such as vectorcardiography (VCG) exist . While the VCG modality offers unique clinical metrics and certain advantages over ECG, it is hardly utilized due to it being more difficult to obtain than ECG. Here we introduce Cardio-Net, a MATLAB-based software that uses standard 12-lead ECG data to generate and visualize VCGs. Furthermore, we demonstrate the diagnostic potential of VCG by utilizing a recurrent neural network (RNN) to accurately classify vectorcardiograms.

Methods: MATLAB version 2019b and the following toolboxes were used for data processing: Deep learning, …

Reduced-Scale Experiments And Numerical Simulations Of Informal Settlement Dwelling Fires, Vigneshwaran Narayanan, Antonio Cicicone, Ayden D. Botha, Richard Shaun Walls

Progress in Scale Modeling, an International Journal

Informal settlement dwellings (ISDs) house approximately one billion people in the developing world and this number is expected to double by the year 2030. Contemporary research on ISD fires has focused on understanding the fire dynamics within individual dwellings (micro-scale) and fire spread in settlements consisting of multiple dwellings (macro-scale). This paper aims to do two primary things: investigate if scaling methods that were derived for compartments with thermally thick boundaries can be applied to ISDs (compartments with thermally thin boundaries), and if they can adequately represent the most important phenomena associated with full-scale ISD fires; and demonstrate Fire Dynamics …

Assessing Public Health Benefits Of Replacing Freight Trucks With Cargo Cycles In Last Leg Delivery Trips In Urban Centers, Jennifer C. Hartle, Ossama (Sam) A. Elrahman, Cara Wang, Daniel A. Rodriguez, Yue Ding, Matt Mcgahan

Mineta Transportation Institute

Increased urbanization, population growth, and demand for time-sensitive deliveries means increased freight movement in cities, which contributes to emissions, noise, and safety concerns. One innovative mode gaining widespread attention for urban deliveries is cargo cycles—bicycles adapted for freight delivery. Despite the recognized potential and possible success of transporting at least 25% of freight via cycle, research remains limited. This research investigates the potential of cargo cycle delivery for last mile freight in Oakland, California, with a focus on the West Oakland neighborhood. The data collection included interviews, focus groups, vehicle field observation and counts, and traffic simulation modeling. The traffic …

Eagle Medical Tray Denesting & Debris Removal Process, Nicholas Allen Ungefug, Noah Chavez, Susana Shu-Lin Okhuysen, Michael Augustine Pennington

Industrial and Manufacturing Engineering

Eagle Medical Incorporated is a contract medical device packaging and sterilization company. The company purchases thermoformed medical packaging trays, which maintain the sterility of medical devices, from various manufacturers. To ensure packaging quality and to prevent cleanroom contamination, Eagle Medical inspects and sterilizes each blister tray that they order. This process is an essential non-value-added activity that creates a bottleneck. Cleanroom employees must stop packaging medical devices and attend to the processing of blister trays and packaging solutions. The blister trays arrive at Eagle’s facility in nested stacks. Vibration and movement during shipping further compresses the stacks, which makes separation …

Variations In Surgeon-Applied Loads During Passive Range Of Motion Following Total Knee Replacement With Relevance To Computational Modeling, Cj Bakle Ii

All Theses

Total knee replacement (TKR) is generally considered a successful treatment for musculoskeletal disorders of the knee. However, as many as 20% of patients report some dissatisfaction in their physical function after TKR. And approximately 50% of early revisions needed to address conditions related to component alignment and soft tissue tension to stabilize the knee. During TKR, surgeons manually perform passive range of motion (ROM) assessments to gain feedback perceived as tension in ligaments and other soft tissues. Such assessments are highly subjective and rely on the surgeon's perception of soft tissue tension rather than quantitative objective means. The variability in …

Covid-19 Public Transportation Air Circulation And Virus Mitigation Study, Aly Tawfik, Deify Law, Juris Grasis, Joseph Oldham, Moe Salem

Mineta Transportation Institute

COVID-19 may have forever changed our world. Given the limited space and air circulation, potential infections on public transportation could be concerningly high. Accordingly, this study has two objectives: (1) to understand air circulation patterns inside the cabins of buses; and (2) to test the impact of different technologies in mitigating viruses from the air and on surfaces inside bus cabins. For the first objective, different devices, metrics and experiments (including colored smoke; videotaping; anemometers; pressure differentials; particle counts; and 3D numerical simulation models) were utilized and implemented to understand and quantify air circulation inside different buses, with different characteristics, …

Development Of A Body Weight Reduction Algorithm In Micro-Gravity Treadmills™, Alexander Hibbert

Master's Theses

Boost Treadmills™, a company specializing in the use of differential air-pressure (DAP) technology in the realm of exercise and rehabilitation, is developing their second-generation micro-gravity treadmill™ named the Boost 2. This machine will allow individuals in all types of fitness environments to move and exercise at a fraction of their normal body weight, reducing the impact forces on lower body extremities and allowing for accelerated returns to activity.

The purpose of this thesis was to create an algorithm to be implemented on the Boost 2 that related the percentage of body weight reduction of a user to a required pressure …

Augmentative And Alternative Communication Use, Service Delivery Experiences, And Communicative Participation For People With Amyotrophic Lateral Sclerosis, Betts Peters

Dissertations and Theses

People with amyotrophic lateral sclerosis (ALS) often experience changes to their speech, and may use augmentative and alternative communication (AAC) devices and techniques to maintain the ability to communicate. The use of AAC may facilitate the participation of people with ALS in various life situations involving communication. There is limited data in the literature about the AAC approaches currently used by people with ALS, the professional services they receive to support communication, or the effects of AAC on their communicative participation. This dissertation involved a nationwide online survey of people with ALS, and comprises three papers intended to add to …

Dietary Practices During Pregnancy In A Marshallese Community: A Mixed Methods Analysis, Britni Ayers, Cari A. Bogulski, Ashlea Bennett-Milburn, Anna Fisher, Morda Newton, Pearl A. Mcelfish

Industrial Engineering Faculty Publications and Presentations

Dietary practices during pregnancy play a pivotal role in the health of women and their children and set the foundation for long-term health. Marshallese women have disproportionally higher rates of maternal and infant health disparities, yet little is known about the dietary practices during their pregnancy. The purpose of this study was to identify dietary practices during pregnancy among Marshallese women. From March 2019 to March 2020, a purposive sample of 33 pregnant Marshallese participants participated in a mixed methods study. Two primary themes emerged: (1) traditional beliefs about a healthy diet during pregnancy; and (2) dietary change during pregnancy. …

Multicolor Fluorescence Guided Surgery For Head And Neck Cancer, Dani Szafran-Reeder

University Honors Theses

This project aims to take a novel, NIR nerve-specific fluorophore LGW05-75⁴ and test its compatibility with a tumor-targeting affibody molecule, ABY-029⁶ that has been labeled with IRDye800CW. The overall goal is to show that these two molecules can be co-administered to show the nerves and tumor cells in real-time to better assist surgeons in a full resection while avoiding iatrogenic nerve damage.

Design Of Self-Assembled Peptides For Wound Healing, Ka-Kyung Kim

Dissertations

According to the CDC, 15% of diabetic patients develop diabetic foot ulcers (DFU) and approximately 170,000 patients undergo non-traumatic amputation annually. DFU is a major complication of diabetes caused by non-healing full-thickness wounds through the dermis. The current treatments include blood sugar control, frequent debridement, offloading, moist wound care, infection treatment, and amputation. To achieve wound closure of DFU, appropriate wound care and antibiotic therapy are essential. Topical regimens include hydrocolloids, alginates, foam, silver-impregnated dressings, and hydrogels. Wound healing is a complex and dynamic interplay between the immune system, keratinocytes, and dermal cells (in case of cutaneous wound). Angiogenesis has …

A Detailed Parameter Study Into The Dermal Absorption Of Chemical Warfare Agents And The Effects Of Pharmacokinetics, Koko Lear

Theses

Chemical warfare agents (CWAs) are substances of varying toxicity profiles. These chemicals exhibit complex dynamics and pose a serious health risk when released into the environment. A mathematical model based on Fick’s second law of diffusion was developed to comprehend how these compounds were absorbed into the skin. The analysis applied to both small and large doses and, successfully, predicted experimental results. This work also includes the effects of CWA physicochemical properties on evaporation and dermal absorption through the stratum corneum. A sensitivity analysis was conducted to assess the impacts of small variations in the initial dose, environmental conditions, and …