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Full-Text Articles in Engineering

Droplet Analysis Of Spray Inside A Compact Column Gas Scrubber Through Shadowgraphy, Brandon Heller Jan 2024

Droplet Analysis Of Spray Inside A Compact Column Gas Scrubber Through Shadowgraphy, Brandon Heller

Theses and Dissertations--Mechanical and Aerospace Engineering

The shadowgraphy imaging technique was adapted to analyze the droplet field from a spray nozzle inside the gas absorption section of a compact column gas scrubber. This technique in conjunction with a developed image processing technique was able to gain statistical size information at different distances from two types of spray nozzles. The gas scrubber then ran a parametric campaign of eight operating conditions and statistical size information was captured for each case with the goal of understanding how operating conditions affect the droplet field properties. Lastly, several simulations were completed to understand how the addition of recirculation zones would …


Microstructure-Based Modeling And Simulation Via A Nonlocal Multiphysics Discrete Approach, Donglai Liu Jan 2024

Microstructure-Based Modeling And Simulation Via A Nonlocal Multiphysics Discrete Approach, Donglai Liu

Theses and Dissertations--Mechanical and Aerospace Engineering

Many structures in engineering are subject to multiphysics loadings or environment. Computational modeling plays a significant role to predict or evaluate the performance of these structures, especially in the scenarios where the experimental investigation is cumbersome or prohibitively expensive. Microstructure-based modeling incorporates the information of microstructures of materials in numerical models, which can provide insights about the relationship between microstructures and mate- rial properties. This research developed a microstructure-based modeling framework for coupling diffusion-deformation simulation of solids. The model is based on a recent developed meshfree method referred to as lattice particle method in the literature. In the developed model, …


Provably Safe Control For Input-Constrained Robotic Systems, Pedram Rabiee Jan 2024

Provably Safe Control For Input-Constrained Robotic Systems, Pedram Rabiee

Theses and Dissertations--Mechanical and Aerospace Engineering

This dissertation addresses challenges in control design for safety-critical robotic systems with input constraints. It focuses on developing novel control barrier function (CBF) approaches to ensure safety while optimizing performance. The work is motivated by the limitations of traditional methods in handling nonlinear systems with multiple constraints and actuator limits.

Three main contributions are presented. First, a soft-minimum barrier function is introduced, utilizing finite-time horizon predictions to create control forward invariant subsets of the safe set while respecting actuator constraints. This method is extended to multiple backup controls, which can enlarge the safe operating region.

Second, a technique for composing …


High-Fidelity Coupling For Studies Of Ablative Materials At Hypersonic Conditions, Aleksander Zibitsker Jan 2024

High-Fidelity Coupling For Studies Of Ablative Materials At Hypersonic Conditions, Aleksander Zibitsker

Theses and Dissertations--Mechanical and Aerospace Engineering

The development of accurate models and robust numerical tools for simulating ablative thermal protection materials (TPMs) in hypersonic flows is crucial for advancing atmospheric entry and hypersonic technologies. Traditional methods for simulating ablative materials often rely on heavy assumptions, such as equal heat and mass transfer coefficients and chemical equilibrium in the boundary layer, leading to conservative thermal protection system (TPS) designs and insufficient accuracy for certain in-flight ablation phenomena.

This work presents a high-fidelity and versatile coupled framework between hypersonic flow and material response solvers. The flow domain is modeled with an innovative overset CHAMPS NBS-Cart solver, which features …


Multiscale Fiber Remodeling In The Heart Using A Finite Element Framework, Mohammad Mehri Jan 2024

Multiscale Fiber Remodeling In The Heart Using A Finite Element Framework, Mohammad Mehri

Theses and Dissertations--Mechanical and Aerospace Engineering

The organization of myofibers and extra cellular matrix within the myocardium plays a significant role in defining cardiac function. When pathological events occur, such as myocardial infarction (MI) or hypertrophic cardiomyopathy (HCM), this organization can become disrupted, leading to alteration in pumping performance. The current study proposes a multiscale finite element (FE) framework to determine realistic fiber distributions in the left ventricle (LV). This is achieved by implementing a stress-based fiber reorientation law, which seeks to align the fibers with local traction vectors, such that contractile force and load bearing capabilities are maximized. By utilizing the total stress (passive and …


Zips Baja Zb25 Frame, Elijah Shelhart Jan 2024

Zips Baja Zb25 Frame, Elijah Shelhart

Williams Honors College, Honors Research Projects

This report outlines the design and validation of a new frame for the University of Akron Zips Baja team’s 2025 competition vehicle. This project represents the first comprehensive redesign of the frame in over a decade, addressing critical issues such as weight and manufacturability identified in previous designs. Utilizing SolidWorks for 3D modeling and Ansys for static simulations, the frame was iteratively improved to ensure structural integrity and compliance with SAE competition rules. The final design achieved a weight reduction of approximately 10 pounds compared to the previous frame while maintaining required safety factors in frontal, rear, rollover, and torsional …


Optimal Tilt-Wing Evtol Takeoff Trajectory Prediction Using Regression Generative Adversarial Networks, Shuan Tai Yeh, Xiaosong Du Jan 2024

Optimal Tilt-Wing Evtol Takeoff Trajectory Prediction Using Regression Generative Adversarial Networks, Shuan Tai Yeh, Xiaosong Du

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Electric vertical takeoff and landing (eVTOL) aircraft have attracted tremendous attention nowadays due to their flexible maneuverability, precise control, cost efficiency, and low noise. The optimal takeoff trajectory design is a key component of cost-effective and passenger-friendly eVTOL systems. However, conventional design optimization is typically computationally prohibitive due to the adoption of high-fidelity simulation models in an iterative manner. Machine learning (ML) allows rapid decision making; however, new ML surrogate modeling architectures and strategies are still desired to address large-scale problems. Therefore, we showcase a novel regression generative adversarial network (regGAN) surrogate for fast interactive optimal takeoff trajectory predictions of …


Nebraska Test #2278: Case Ih Steiger 475, Nebraska Tractor Test Lab Jan 2024

Nebraska Test #2278: Case Ih Steiger 475, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …


Tractor Test #2294: Kubota M7-154, Nebraska Tractor Test Lab Jan 2024

Tractor Test #2294: Kubota M7-154, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …


Tractor Test #2286: Claas 960 Terra Trac, Nebraska Tractor Test Lab Jan 2024

Tractor Test #2286: Claas 960 Terra Trac, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …


Nebraska Test #2290: Case Ih Steiger 555 Quadtrac, Nebraska Tractor Test Lab Jan 2024

Nebraska Test #2290: Case Ih Steiger 555 Quadtrac, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data. EXPLANATION OF THE TEST PROCEDURES Purpose The purpose of …


Identifying Savings In Residential Electricity Consumption Through Data-Driven Analysis, Scott J. Maurer Jan 2024

Identifying Savings In Residential Electricity Consumption Through Data-Driven Analysis, Scott J. Maurer

Dartmouth College Master’s Theses

Climate change and rising electricity demand have driven the need for energy efficiency in buildings. Single-family residential buildings present opportunities for improvement, but current strategies for identifying savings are labor and capital-intensive. Developing a residential version of a virtual energy audit tool offers a cheaper, non-intrusive alternative. This study used 25 all-electric homes in Florida to refine algorithms from the previously developed EDIFES code, originally designed for commercial buildings. The analysis utilized one year of 15-minute electricity consumption, area, stories, and location. These markers include heating and cooling type, setpoint set back, HVAC load, pool pump load, refrigeration load, and …


Stable Energy-Efficient Macro-Scale Partial Flow-Boiling Operations Using Microstructured Surfaces And Ultrasonics, Divya Kamlesh Pandya Jan 2024

Stable Energy-Efficient Macro-Scale Partial Flow-Boiling Operations Using Microstructured Surfaces And Ultrasonics, Divya Kamlesh Pandya

Dissertations, Master's Theses and Master's Reports

Controlled but explosive growth in vaporization rates is made feasible by ultrasonic acoustothermal heating of the microlayers associated with micro-scale nucleating bubbles within the microstructured boiling surface/region of a millimeter-scale single-channel heat exchanger (HX) – part of a typically multi-channel heat-sink. The experiments illustrate the achievement of a remarkably high stable heat flux (10 – 80 W/cm2) for a partial flow-boiling-based cooling approach and exceptional efficiency through active/passive enhancement in the vaporization rates into the heterogeneously nucleated micro-bubbles (through acoustothermal heating of their microlayers) and their removal rates (typically within the passive microstructured region of boiling). A controlled …


Directional Dependent Fracture Characteristics Of 3d Printed Mechanical Metamaterials, Thomas Draper Jan 2024

Directional Dependent Fracture Characteristics Of 3d Printed Mechanical Metamaterials, Thomas Draper

Dissertations, Master's Theses and Master's Reports

Structural metamaterials, such as lattice metamaterials, are engineered cellular structures designed to achieve properties not achievable by natural materials. They enable mechanical properties unattainable by homogeneous solid materials and offer optimal properties for these materials tunable for specific applications in industries such as automotive, medical, and aerospace. Recent findings have revealed unique tunable mechanical properties such as negative Poisson's ratio, high strength-to-weight ratio, anisotropic stiffness, and much more. While the elastic and wave propogation properties of many lattice metamaterials are well investigated, the fracture properties are not well explored. However, their low fracture toughness is a bottleneck for their use …


Design, Testing And Neural Network Modeling Of A Low-Friction Wave Energy Converter Testbed, Vasu Bhardwaj Jan 2024

Design, Testing And Neural Network Modeling Of A Low-Friction Wave Energy Converter Testbed, Vasu Bhardwaj

Dissertations, Master's Theses and Master's Reports

Point absorber wave energy converters (WECs) transform water wave kinetic energy into other useful forms, typically electrical. While it’s possible to extract energy from passive WECs, more energy can be captured using active control where its power take-off (PTO) acts as both a generator and an actuator. Control strategies usually require accurate models often obtained during model-scale testing. Unfortunately, friction can dominate the dynamic response in small WEC models. A frictionless point absorber WEC testbed is described in this report which allows the researcher to focus on fundamental hydrodynamic behavior instead of friction. It uses air bearings for vertical motion …


Wave Energy Converter Wave Force Prediction Using A Neural Network, Morgan Kline Jan 2024

Wave Energy Converter Wave Force Prediction Using A Neural Network, Morgan Kline

Dissertations, Master's Theses and Master's Reports

Due to the unpredictable nature of large bodies of water, wave energy can be a difficult renewable resource to rely on. One way to make Wave Energy Converters (WECs) more efficient is to apply a control strategy. In many control solutions, it is assumed that the wave excitation force is known into the future. In many instances, especially with complex waveforms, this is simply not the case. Simulation studies have shown the promise of wave force prediction using neural networks. This study demonstrates this experimentally and aims to characterize the important factors when designing such a network. Several wave elevation …


Data To Physics: Bridging Modeling Frameworks For Metastructures, Hrishikesh Suhas Gosavi Jan 2024

Data To Physics: Bridging Modeling Frameworks For Metastructures, Hrishikesh Suhas Gosavi

Dissertations, Master's Theses and Master's Reports

The effective attenuation of wave propagation in specific frequency ranges, known as bandgaps, makes metastructures valuable in various engineering applications. Traditionally, bandgap estimation has relied on physics-based models, which present challenges for complex metastructures where accurate material properties and geometric complexities make precise modeling difficult. This work introduces data-driven techniques for bandgap estimation, leveraging the dynamic behavior, particularly the Frequency Response Functions (FRFs) of unit cells, to calculate dispersion relations and couple unit cells through dynamic substructuring. This approach addresses the limitations of traditional methods by directly utilizing experimental data to characterize both longitudinal and flexural bandgaps.

To evaluate data-driven …


Fatigue Resistant Cast Steel Railcar Couplers Produced By Wire-Arc Additive Manufacturing (Waam), Samuel Vellequette Jan 2024

Fatigue Resistant Cast Steel Railcar Couplers Produced By Wire-Arc Additive Manufacturing (Waam), Samuel Vellequette

Dissertations, Master's Theses and Master's Reports

Every year, approximately 90,000 cast steel railcar coupler knuckles are replaced preemptively to avoid fatigue failure. The coupler geometry has been in service since the early 1930s, so geometry changes are restricted to maintain compatibility with the existing fleet. Defects from the casting process, decarburization during heat treatment, and in-service exposure to corrosive environments combine to promote fatigue crack nucleation in high-stress regions of the knuckle. Wire-arc additive manufacturing (WAAM), which uses traditional welding techniques to build material to near-net shapes, was employed to deposit higher-strength materials in critical regions. By replacing the cast steel in the high-stress region of …


Investigation Of Operational Parameter Differences Between The Standard Ron Test Method And Knock-Limited Modern Spark-Ignition Engine Operation, Alexander Hoth Jan 2024

Investigation Of Operational Parameter Differences Between The Standard Ron Test Method And Knock-Limited Modern Spark-Ignition Engine Operation, Alexander Hoth

Dissertations, Master's Theses and Master's Reports

Octane numbers (ONs) are used worldwide to rate the knock propensity of gasoline-like fuels for spark-ignition engines, making ONs the leading indicator of fuel quality for commercial distribution. The ONs were established 90 years ago and have only received minor changes compared to significant advancements in modern engine operation and fuel composition. This has resulted in discrepancies between knock-limited modern engine operation and standard ON ratings. This dissertation used a standard CFR octane rating engine at Argonne National Laboratory that was instrumented with modern combustion research tools to investigate key differences between the Research Octane Number (RON) rating conditions and …


Pulse-Width Modulation Spray System Performance And Development Of A Novel System To Optimize Spray Use Efficacy, Prashanta Pokharel Jan 2024

Pulse-Width Modulation Spray System Performance And Development Of A Novel System To Optimize Spray Use Efficacy, Prashanta Pokharel

Theses and Dissertations--Biosystems and Agricultural Engineering

The overarching objective of this research was to enhance our understanding of pulse width modulation (PWM) based nozzle control system and develop an intelligent nozzle control system for agricultural spray applications. This dissertation focused on measuring and analyzing the transient nozzle pressure characteristics and performance under PWM control. Additionally, it explored the development of an innovative multi-degree-of-freedom (DOF) nozzle control system for precise chemical applications in specialty crop systems.

The pressure dynamics of a PWM system were studied by developing an instrumentation system capable of operating a solenoid valve and recording pressure signals. A nozzle body and two manifolds of …


Improving The Peak Performance Lifespan Of A Two-Piece Composite Bat, Angelina Sicurezza Jan 2024

Improving The Peak Performance Lifespan Of A Two-Piece Composite Bat, Angelina Sicurezza

Williams Honors College, Honors Research Projects

The push for innovation and enhancement of sports equipment in recent years has led to significant advancements in composite materials. This project aims to propose new design possibilities that will improve the lifespan of a two-piece composite bat. Using finite element analysis (FEA) software, various fiber orientations and materials were modeled and analyzed for their impact response. Two unique quarter-cylinder designs along with a baseline design were modeled with symmetric boundary conditions. The proposed bat deigns include a helicoidal model and a CFRP-Aramid hybrid model. Comparative analysis of the elastic responses revealed that both the helicoidal and hybrid models demonstrated …


Parametrization Of Fluid Models For Electrical Breakdown Of Nitrogen At Atmospheric Pressure, Shirshak K. Dhali Jan 2024

Parametrization Of Fluid Models For Electrical Breakdown Of Nitrogen At Atmospheric Pressure, Shirshak K. Dhali

Electrical & Computer Engineering Faculty Publications

In the transient phase of an atmospheric pressure discharge, the avalanche turns into a streamer discharge with time. Hydrodynamic fluid models are frequently used to describe the formation and propagation of streamers, where charge particle transport is dominated by the creation of space charge. The required electron transport data and rate coefficients for the fluid model are parameterized using the local mean energy approximation (LMEA) and the local field approximation (LFA). In atmospheric pressure applications, the excited species produced in the electrical discharge determine the subsequent conversion chemistry. We performed the fluid model simulation of streamers in nitrogen gas at …


1d Granular Chains Of Closed-Cell Pvc Foams Under Low And Medium Velocity Impacts, Vikranth Kumar Reddy Madhirala Jan 2024

1d Granular Chains Of Closed-Cell Pvc Foams Under Low And Medium Velocity Impacts, Vikranth Kumar Reddy Madhirala

Open Access Dissertations

Chapter 1: This study experimentally analyses the deformation and energy retention behavior often closed-cell PVC foam disks constituting a one-dimensional granular chain subjected to low-velocity impacts. A pressure-driven impactor loads disk chains of two densities, each at 1 and 10 m/s. The deformations of the disks are captured using high-speed cameras, and the chain’s input and output forces are recorded during the impact. Energy retained by the chain and the disks is calculated using the deformations of the disks, input, output, and contact forces. The results show that the energy retained by the chain of H130 foam is 3 …


A Strategic Framework For Estimating International Container Flows: An Empirical Study, Dung-Ying Lin, Hsin-Chun Huang, Steven Travis Waller, Xiang Zhang Jan 2024

A Strategic Framework For Estimating International Container Flows: An Empirical Study, Dung-Ying Lin, Hsin-Chun Huang, Steven Travis Waller, Xiang Zhang

Journal of Marine Science and Technology–Taiwan

Maritime transportation is a highly complex transportation system that plays a pivotal role in international trade. Its low-cost and high-volume advantages have enabled it to cover most of the world’s cargo transportation. However, with the trend of global trade volume increasing almost every year and the recent congestion of ports due to the COVID-19 pandemic, the chaos in global supply chains not only increases operating costs for shippers but also makes it difficult for countries that rely heavily on port trade to plan for their ports’ future. To develop a strategic analytic tool to estimate container flow in liner shipping, …


An Application Of Cfd To Support The Development Of Treatment Strategies And Technology For The Management Of Cystic Fibrosis In Pediatric Patients, Morgan L. Thomas Jan 2024

An Application Of Cfd To Support The Development Of Treatment Strategies And Technology For The Management Of Cystic Fibrosis In Pediatric Patients, Morgan L. Thomas

Theses and Dissertations

Inhaled medications are a key treatment modality in multiple lung-related diseases and disorders. Considering children with cystic fibrosis (CF), improvements in the delivery of aerosol antibiotics have the potential to better eradicate bacterial lung infections, preserve lung function and thereby further extend lifespans and quality of life. The overall objective of this dissertation was to expand and validate CFD models for predicting the deposition of pharmaceutical aerosols throughout the airways and apply these models to understand the targeted delivery of inhaled antibiotics to children with CF. To accomplish this goal, three contributions were made. First, CFD methodologies for modeling aerosol …


High-Pressure Ignition And Flame Propagation – An Experimental And Numerical Study, James Shaffer Jan 2024

High-Pressure Ignition And Flame Propagation – An Experimental And Numerical Study, James Shaffer

Graduate Theses, Dissertations, and Problem Reports (ETD)

The next generation of advanced combustion devices is being developed to operate under ultra-high-pressure conditions, to improve combustion efficiency and reduce pollutant emissions. However, at such extreme conditions, flame tends to become unstable, and measurement of fundamental properties becomes challenging. The laminar burning speed ( ) is among those properties, as it is required for the validation of kinetic models and the modeling of turbulent combustion. One potential method to resolve this issue and achieve measurement at very high pressures (i.e., 20-50 atm), is focusing on ignition affected region. The flame kernel in this region is more resistant to perturbations …


Investigation Of Space Charge Effects On Co2 Electrocatalytic Reduction On Gd-Doped Ceria Via Scanning Kelvin Probe And Model-Based Bayesian Analysis, Alejandro Mejia Jan 2024

Investigation Of Space Charge Effects On Co2 Electrocatalytic Reduction On Gd-Doped Ceria Via Scanning Kelvin Probe And Model-Based Bayesian Analysis, Alejandro Mejia

Graduate Theses, Dissertations, and Problem Reports (ETD)

In studying novel energy conversion and storage systems, such as high-temperature electrolysis, numerous underlying fundamental physical processes remain unclear or inadequately understood. Among these, the modeling and comprehension of surface reaction mechanisms, coupled with the intricate effects of space‑charge interfaces, remains an unclear and challenging area of research.

The work of this dissertation involves the development of a 2D finite element analysis model, leveraging the robust MOOSE framework from INL. This model, featuring inhomogeneous defect thermodynamics for near-surface chemistry, formulated through Poisson‑Cahn variational theory, has been exploited for studying the electrocatalytic reduction of CO2 on gadolinia doped ceria. The …


Data-Driven Modeling Of Oxygen Kinetics In La0.6sr0.4co0.2fe0.8o3−Δ (Lscf) For High-Temperature Reduction Of Co2 In An Electrolysis Cell, Ferron Campbell Jan 2024

Data-Driven Modeling Of Oxygen Kinetics In La0.6sr0.4co0.2fe0.8o3−Δ (Lscf) For High-Temperature Reduction Of Co2 In An Electrolysis Cell, Ferron Campbell

Graduate Theses, Dissertations, and Problem Reports (ETD)

Electrolysis systems are critical to several societal applications, particularly energy storage and conversion. Developing these systems requires a detailed knowledge of the chemistry and thermodynamics of the materials used in the electrolysis cell. This work focuses on using embedded scientific machine learning as an efficient way to build an interpretable model for the reaction and transport kinetics in the LSCF electrode, whose performance directly influences the electrolysis system’s performance. The models developed in this study are trained using the publicly available machine learning package, FoKL-GP. This package incorporates a robust Gibbs sampler that employs a forward variable selection process to …


Enhancing Robotic Exploration Through Semantically-Guided Sampling Strategies, Christopher Alexander Arend Tatsch Jan 2024

Enhancing Robotic Exploration Through Semantically-Guided Sampling Strategies, Christopher Alexander Arend Tatsch

Graduate Theses, Dissertations, and Problem Reports (ETD)

From space and deep-sea exploration to disaster response and environmental monitoring, autonomous robots are essential for advancing science, improving safety, and addressing critical challenges. This dissertation introduces a novel open-source strategy for autonomous robotic exploration: the Semantically-Guided Exploration (SGE) framework. Designed for ground vehicles, SGE integrates semantic understanding into the autonomous exploration process, improving decision-making in complex environments. Specifically, the proposed sampling-based approach uses the information from the semantic segmentation of RGB images and depth images to guide the robot's selection of exploration goals. This method enables the robot to steer away from potential dangers such as large rocks and …


Ifn-𝜸 And Il-10 Immunosensor With Vertically Aligned Carbon Nanotube Interdigitated Electrodes Toward Pen-Side Cattle Paratuberculosis Monitoring, Shaowei Ding, Benjamin J. Brownlee, Kshama Parate, Cicero C. Pola, Bolin Chen, Jesse M. Hostetter, Douglas Jones, John Jackman, Brian D. Iverson, Jonathan C. Claussen Jan 2024

Ifn-𝜸 And Il-10 Immunosensor With Vertically Aligned Carbon Nanotube Interdigitated Electrodes Toward Pen-Side Cattle Paratuberculosis Monitoring, Shaowei Ding, Benjamin J. Brownlee, Kshama Parate, Cicero C. Pola, Bolin Chen, Jesse M. Hostetter, Douglas Jones, John Jackman, Brian D. Iverson, Jonathan C. Claussen

Faculty Publications

Highly sensitive vertically aligned carbon nanotube arrays (VANTAs) interdigitated electrode (IDE) arrays are developed for electrochemical biosensing of two cytokines (i.e., interleukin-10 (IL-10) and interferon-gamma (IFN-𝜸)) that are useful for early detection Johne’s disease (Bovine Paratuberculosis) in cattle. The high aspect ratio VANTA-IDEs (50–60 μm in height) are grown through a chemical vapor deposition process from an iron (Fe) catalyst that is lithographically patterned on a silicon wafer with equal finger width and inter-finger spacing of 25 μm. After functionalization with distinct antibodies the VANTA-IDEs are capable of selective detection of both IL-10 and IFN-𝜸 within an actual biological matrix …