Engineering Commons^™

Extrinsic And Intrinsic Control Of Integrative Processes In Neural Systems, Anirban Nandi

McKelvey School of Engineering Graduate Student Theses & Dissertations

At the simplest dynamical level, neurons can be understood as integrators. That is, neurons accumulate excitation from afferent neurons until, eventually, a threshold is reached and they produce a spike. Here, we consider the control of integrative processes in neural circuits in two contexts. First, we consider the problem of extrinsic neurocontrol, or modulating the spiking activity of neural circuits using stimulation, as is desired in a wide range of neural engineering applications. From a control-theoretic standpoint, such a problem presents several interesting nuances, including discontinuity in the dynamics due to the spiking process, and the technological limitations associated with …

Characterizing Anisotropy In Fibrous Soft Materials By Mr Elastography Of Slow And Fast Shear Waves, John Larson Schmidt

McKelvey School of Engineering Graduate Student Theses & Dissertations

The general objective of this work was to develop experimental methods based on magnetic resonance elastography (MRE) to characterize fibrous soft materials. Mathematical models of tissue biomechanics capable of predicting injury, such as traumatic brain injury (TBI), are of great interest and potential. However, the accuracy of predictions from such models depends on accuracy of the underlying material parameters. This dissertation describes work toward three aims. First, experimental methods were designed to characterize fibrous materials based on a transversely isotropic material model. Second, these methods are applied to characterize the anisotropic properties of white matter brain tissue ex vivo. Third, …

Soft Foam Robot With Caterpillar-Inspired Gait Regimes For Terrestrial Locomotion, Cassandra M. Donatelli, Zachary T. Serlin, Piers Echols-Jones, Anthony E. Scibelli, Alexandra Cohen, Jeanne-Marie Musca, Shane Rozen-Levy, David Buckingham, Robert White, Barry A. Trimmer

Engineering Faculty Articles and Research

Caterpillars are the soft bodied larvae of lepidopteran insects. They have evolved to occupy an extremely diverse range of natural environments and to locomote in complex three-dimensional structures without articulated joint or hydrostatic control. These animals make excellent bio-inspiration for the field of soft robotics because of their diversity and adaptability. In this paper, we present SquMA Bot, a caterpillar-inspired soft robot. The robot's body is primarily composed of a soft viscoelastic foam, and it is actuated using a motor-tendon system. SquMA Bot is able to mimic the inching gait of a caterpillar and can use its flexible body to …

Nanostructured Apatite-Mullite Glass-Ceramics For Enhanced Primary Human Osteoblast Cell Response, Gordon Cooke, Conor Dunne, Sarah Keane, Daithi De Faoite, Seamas Donnelly, Kenneth Stanton

Articles

This work investigates the difference in viability of primary human foetal osteoblast cells on a glass-ceramic surface with nanoscale topography relative to viability on a smooth glass-ceramic surface containing a bioactive phase. Apatite-mullite glass-ceramics containing bioactive fluorapatite (Ca₁₀(PO₄)₆F₂) and bioinert mullite (Si₂Al₆O₁₃) were synthesised and subsequent heat-treatment was optimised to form nano-sized fluorapatite crystals. Etching was used to selectively remove the bioactive phase, producing a surface with disordered nanoscale topography. Cells were seeded onto a smooth polished glass-ceramic substrate with the bioactive phase intact, an etched …

Habitat Use Of Blacktip Sharks (Carcharhinus Limbatus) At Fishing Piers, Kelsey L. Spencer

Electronic Theses and Dissertations

Blacktip sharks (Carcharhinus limbatus) can be observed near fishing piers throughout the summer along the northeast coast of South Carolina. These piers attract and support a wide variety of potential prey and sharks are able to forage on fishers’ discards with minimal energetic cost. I tagged 12 blacktip sharks with acoustic transmitters, monitored piers with acoustic receivers, and conducted pier-creel surveys to determine the habitat use of blacktip sharks at fishing piers, factors that influenced residence time and presence/absence at piers, and any cyclical patterns in visits to piers. Data were analyzed with pier association indices (PAI), mixed models, and …

Reducing Biomass Recalcitrance By Heterologous Expression Of A Bacterial Peroxidase In Tobacco (Nicotiana Benthamiana), Ayalew Ligaba-Osena, Bertrand Hankoua, Kay Dimarco, Robert Pace, Mark Crocker, Jesse Mcatee, Nivedita Nagachar, Ming Tien, Tom L. Richard

Center for Applied Energy Research Faculty and Staff Publications

Commercial scale production of biofuels from lignocellulosic feed stocks has been hampered by the resistance of plant cell walls to enzymatic conversion, primarily owing to lignin. This study investigated whether DypB, the lignin-degrading peroxidase from Rodococcus jostii, depolymerizes lignin and reduces recalcitrance in transgenic tobacco (Nicotiana benthamiana). The protein was targeted to the cytosol or the ER using ER-targeting and retention signal peptides. For each construct, five independent transgenic lines were characterized phenotypically and genotypically. Our findings reveal that expression of DypB in the cytosol and ER does not affect plant development. ER-targeting increased protein accumulation, and …

Development And Testing Of An Agricultural Nozzle Clog Detection Device Prototype, Chin Nee Vong

Student Theses and Dissertations

Nozzle clogging during spray application results in poor weed management and increased cost in re-spraying. A device that can detect nozzle clogging during the spraying operation is necessary. A novel method and device for detecting clogged nozzles that is externally attachable to each nozzle on the sprayer’s boom has been developed in the Precision Application Technology Lab at Arkansas State University. The study’s objectives include developing prototypes of this device and comparing the spray droplet size and spray pattern in controlled condition and spray coverage in field condition with and without using the device. The research demonstrated that this new …

Note From The Editorial Board

Dartmouth Undergraduate Journal of Science

No abstract provided.

Telesurgery: Surgery In The Digital Age, Dylan J. Cahill

Dartmouth Undergraduate Journal of Science

The dawn of the digital age has transformed the way we now receive and provide healthcare. Today, providers have instant access to all of their patients’ information, just as patients can connect with their providers on their smartphones in minutes from nearly anywhere in the world.

Lyme Disease: An Influential Outdoor Hazard, Kevin Kang

Dartmouth Undergraduate Journal of Science

Lyme disease is an important, common illness in New England. A relatively new illness, it was discovered about forty years ago in the town of Lyme, Connecticut. Now, it has become the most common vector-transmitted illness in the United States, with over 30,000 cases annually. Lyme disease arises when a bacterium is transmitted to a human via deer tick bite, so those of us involved in outdoor sports are most likely to contract the disease. Inhabitants of New England and the northeastern U.S. are most vulnerable to the disease, as 95% of Lyme Disease cases occur in only 14 out …

Towards Simulating The Human Brain, Logan T. Collins

Dartmouth Undergraduate Journal of Science

The human brain has been described as “the most complex object in the universe.” Its meshwork of 86 billion neurons,84 billion glial cells, and over 150 trillion synapses may seem intractable. Nonetheless, efforts to comprehensively map, understand, and even computationally reproduce this structure are underway. Large collectives of researchers have come together, working in concert towards these goals. The Human Brain Project (HBP) and its precursor, the Blue Brain Project, have spearheaded the brain simulation goal.Some other notable organizations include the China Brain Project, the BRAIN Initiative. On a scale which parallels the space program and the Human Genome Project, …

Effectiveness Of Chain Link Turtle Fence And Culverts In Reducing Turtle Mortality And Providing Connectivity Along U.S. Hwy 83, Valentine National Wildlife Refuge, Nebraska, Usa, Marcel P. Huijser, Kari E. Gunson, Elizabeth R. Fairbank

Nebraska Department of Transportation: Research Reports

We evaluated the effectiveness of existing turtle fences through collecting and analyzing turtle mortality data along U.S. Hwy 83, in and around Valentine National Wildlife Refuge, Nebraska, USA. We also investigated the level of connectivity for turtles provided through the culverts that were originally designed to pass water through a capture-mark-recapture experiment. While fenced valley sections had 33.1% fewer turtle observations than unfenced valley sections, the difference was not significant. However, we think that the effectiveness of the fence can be improved through fence repairs, other modifications of the fences, vegetation maintenance, and extending the length of the fences. Four …

Analytical Modeling Of A Communication Channel Based On Subthreshold Stimulation Of Neurobiological Networks, Alireza Khodaei

School of Computing: Dissertations, Theses, and Student Research

The emergence of wearable and implantable machines manufactured artificially or synthesized biologically opens up a new horizon for patient-centered health services such as medical treatment, health monitoring, and rehabilitation with minimized costs and maximized popularity when provided remotely via the Internet. In particular, a swarm of machines at the scale of a single cell down to the nanoscale can be deployed in the body by the non-invasive or minimally invasive operation (e.g., swallowing and injection respectively) to perform various tasks. However, an individual machine is only able to perform basic tasks so it needs to exchange data with the others …

Papermaking Factors Affecting Lateral Web Position During Commercial Heat Set Web Offset Printing, George W. Shields

Masters Theses

The interaction of water with paper plays a role in web handling characteristics during commercial heat set web offset printing. Water absorption leads to lower web tension for a given strain.

This research investigates paper properties and their role in preventing lateral web movement from cross machine air flows in the drying section during normal printing operations. Tensile properties of sheets are measured at various moisture contents and then used to determine the equilibrium stress-strain relationship for papers at moisture contents typical of heat set web offset printing. Permeability, fiber orientation and tensile stiffness are evaluated against lateral web movement …

A Risk-Based Method For Estimating The Carbon Sequestration Budget For A Mixed Hardwood Forest, Erin Cooper

Chemical Engineering Undergraduate Honors Theses

Carbon Dioxide (CO₂) levels in the atmosphere have risen from approximately 310 ppm in the 1950’s to over 400 ppm as of 2015. This rise in CO₂ has likely resulted in the observed warming trend of the earth’s atmosphere in the same time frame, causing significant concern in the scientific community. Several mitigation strategies have arisen to combat the upward trend of CO₂ emissions in recent decades, among them being carbon sequestration- the process of capturing CO₂ from the atmosphere and holding it for an extended period of time. This study used the U.S. Forest …

Morphological, Thermal And Oxygen Barrier Properties Plasticized Film Polylactic Acid, Kurniawan Yuniarto, Bruce A. Welt, Foliatini -, Hanafi -, Candra Irawan

Journal of Applied Packaging Research

Introducing plasticizer poly(ethylene glycol) (PEG400) was applied into poly(lactic acid) (PLA) to produce film matrix packaging by direct casting. Non mechanical properties were carried out plasticized PLA including morphology, crystallinity structure and degree, thermal properties and oxygen barrier properties. Plasticized PLA revealed improving surface structure of PLA film matrix form fractures and homogenous film were achieved at 5% PEG 400. Chromatogram PLA and plasticized PLA were categorized crystal structure an α-form crystal. Intercalated and exfoliated structure did not occur significantly due to dispersion PEG 400 in the matrix but indicated dispersion structure. Thermal properties did not improve plasticized PLA significantly …

18f-Fdg Pet/Ctct-Based Radiomics For The Prediction Of Radiochemotherapy Treatment Outcomes Of Cervical Cancer, Badereldeen Abdulmajeed Altazi

USF Tampa Graduate Theses and Dissertations

Cervical cancer remains the third most commonly diagnosed gynecological malignancy in the United States and throughout the world despite being potentially preventable. Patients diagnosed with cervical cancer may develop local recurrence in the cervix and surrounding structures (vaginal apex, parametrial, or paracervical), regional recurrence in pelvic lymph nodes, distant metastasis, or a combination of all. The management of such treatment outcomes has not been subject to rigorous investigation. Therefore, there is a need for studies and clinical trials that focus on decision making to support the choice of the best treatment modality that leads to the minimal number of adverse …

The Santa Clara, 2017-11-16, Santa Clara University

The Santa Clara

No abstract provided.

Both Adhe And A Separate Nadph-Dependent Alcohol Dehydrogenase Gene, Adha, Are Necessary For High Ethanol Production In Thermoanaerobacterium Saccharolyticum, Tianyong Zheng, Daniel G. Olson, Sean J. Murphy, Xiongjun Shao, Liang Tian, Lee Lynd

Dartmouth Scholarship

Thermoanaerobacterium saccharolyticum has been engineered to produce ethanol at ∼90% theoretical yield and titer of 70 g/L. Its ethanol-producing ability has drawn attention to its metabolic pathways, which could potentially be transferred to other organisms of interest. Here we report that the iron-containing AdhA is important for ethanol production in the high-ethanol strain of T. saccharolyticum (LL1049). A single-gene deletion of adhA in LL1049 reduced ethanol production by ∼50%, whereas multiple gene deletions of all annotated alcohol dehydrogenases except adhA and adhE did not affect ethanol production. Deletion of adhA in wild-type T. saccharolyticum reduced NADPH-linked ADH activity (acetaldehyde-reducing) by …

Ncer Assistance Agreement Annual Progress Report For Grant #83582401 - Assessment Of Stormwater Harvesting Via Manage Aquifer Recharge (Mar) To Develop New Water Supplies In The Arid West: The Salt Lake Valley Example, Ryan Dupont, Joan E. Mclean, Richard C. Peralta, Sarah E. Null, Douglas B. Jackson-Smith

Civil and Environmental Engineering Faculty Publications

The aims of the original proposed project remain the same, that is, to test the hypothesis that Managed Aquifer Recharge (MAR) for stormwater harvesting is a technically feasible, socially and environmentally acceptable, economically viable, and legally feasible option for developing new water supplies for arid Western urban ecosystems experiencing increasing population, and climate change pressures on existing water resources. The project is being carried out via three distinct but integrated components that include: 1) Monitoring of existing distributed MAR harvesting schemes involving a growing number of demonstration Green Infrastructure (GI) test sites; 2) Integrated stormwater/vadose zone/groundwater/ ecosystem services modeling; and …

The Santa Clara, 2017-11-09, Santa Clara University

The Santa Clara

No abstract provided.

Rehabilitating Asymmetric Gait Using Asymmetry, Tyagi Ramakrishnan

USF Tampa Graduate Theses and Dissertations

Human gait is a complex process that involves the coordination of the central nervous and muscular systems. A disruption to the either system results in the impairment of a person’s ability to walk. Impairments can be caused by neurological disorders such as stroke and physical conditions like amputation. There is not a standardized method to quantitatively assess the gait asymmetry of affected subjects. The purpose of this research is to understand the fundamental aspects of asymmetrical effects on the human body and improve rehabilitation techniques and devices. This research takes an interdisciplinary approach to address the limitations with current rehabilitation …

2015 - Salinas River Watershed Area Salt Modeling Assessment Prepared For California Central Coast Regional Water Quality Control Board And The U.S. Environmental Protection Agency, Region Ix

Miscellaneous Monterey and San Luis Obispo County Documents and Reports

A November 2015 report prepared by Tetra Tech for California Central Coast Regional Water Quality Control Board and the U.S. Environmental Protection Agency, Region IX. The purpose was for the informed development of salt-related TMDLs by the CCRWQCB and a salt and nutrient management plan for the Salinas Valley aquifers. Three reaches reported 2010 303(d) listings for salt-related impairments in these watersheds including impairments due to chloride, sodium, electrical conductivity, and total dissolved solids – Lower Salinas River, Santa Rita Creek, and Alisal Creek. This report provides data analysis and a literature review (Sections 1 through 5), development of a …

Individual And Community Well-Being In Nonmetropolitan Nebraska: 2017 Nebraska Rural Poll Results, Rebecca J. Vogt, Cheryl A. Burkhart-Kriesel, Randolph L. Cantrell, Bradley Lubben, L. J. Mcelravy, T. L. Meyer

Rural Futures Institute: Publications

Conclusion

By many different measures, rural Nebraskans are positive about their community. Many rural Nebraskans rate their community favorably on its social dimensions: as friendly, trusting and supportive. Most rural Nebraskans say it would be difficult to leave their community and have a positive attachment to their community. And, most rural Nebraskans disagree that their community is powerless to control its future.

Across all years of this study, rural Nebraskans’ views about the change in their community have generally been positive. The proportion believing their community has changed for the better during the past year has usually been greater than …

The Santa Clara, 2017-11-02, Santa Clara University

The Santa Clara

No abstract provided.

An Optimal Milk Production Model Selection And Configuration System For Dairy Cows, Fan Zhang

PhDs

Milk production forecasting in the dairy industry has been an independent research topic since the early 20th century. The accurate prediction of milk yield can benefit both the processor (creameries) and the producer (dairy farmer) through developing short-term production schedules, planning long-term road maps, facilitating trade and investment in the dairy industry, improving business operations, optimising the existing infrastructure of the dairy industry, and reducing operating costs. Additionally, due to the innate characteristics of the milk production process, the accurate prediction of milk yield has been a challenging issue in the dairy industry. With the abolishment of EU milk quotas …

Classification Of Rest And Active Periods In Actigraphy Data Using Pca, Isaac W. Muns, Yogesh Lad, Ivan G. Guardiola, Matthew S. Thimgan

Engineering Management and Systems Engineering Faculty Research & Creative Works

In this paper we highlight a clustering algorithm for the purpose of identifying sleep and wake periods directly from actigraphy signals. The paper makes use of statistical Principal Component Analysis to identify periods of rest and activity. The aim of the proposed methodology is to develop a quick and efficient method to determine the sleep duration of an individual. In addition, a robust method that can identify sleep periods in the accelerometer data when duration, time of day varies by individual. A selected group of 10 individual's sensor data consisting of actigraphy from an accelerometer (3-axis), near body temperature, and …

The Santa Clara, 2017-10-26, Santa Clara University

The Santa Clara

No abstract provided.

Pattern Discovery In Brain Imaging Genetics Via Scca Modeling With A Generic Non-Convex Penalty, Lei Du, Kefei Liu, Xiaohui Yao, Jingwen Yan, Shannon L. Risacher, Junwei Han, Lei Guo, Andrew J. Saykin, Li Shen, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, John Morris, Leslie M. Shaw, Zaven Khachaturian, Greg Sorensen, Maria Carrillo, Lew Kuller, Marc Raichle, Steven Paul, Peter Davies, Howard Fillit, Franz Hefti, David Holtzman, Charles D. Smith, Gregory Jicha, Peter A. Hardy, Partha Sinha, Elizabeth Oates, Gary Conrad

Neurology Faculty Publications

Brain imaging genetics intends to uncover associations between genetic markers and neuroimaging quantitative traits. Sparse canonical correlation analysis (SCCA) can discover bi-multivariate associations and select relevant features, and is becoming popular in imaging genetic studies. The L1-norm function is not only convex, but also singular at the origin, which is a necessary condition for sparsity. Thus most SCCA methods impose ℓ₁-norm onto the individual feature or the structure level of features to pursuit corresponding sparsity. However, the ℓ₁-norm penalty over-penalizes large coefficients and may incurs estimation bias. A number of non-convex penalties are proposed to reduce …

2017, October - Recommendations To Address The Expansion Of Seawater Intrusion In The Salinas Valley Groundwater Basin

Monterey County Water Resources Agency Engineering Reports

This report provides a discussion of the current knowledge and related background information surrounding seawater intrusion pathways and potential impacts thereof on the Salinas Valley Groundwater Basin. The report also serves as a body of evidence to catalogue the findings used to support the six recommendations presented. Each recommendation can be implemented on its own or in concert with the others, and the relative importance of each is discussed individually in this report. However, the recommendations are conceptualized as a comprehensive solution that, along with continued operation of projects that have been constructed for the same purpose, have the strongest …