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Full-Text Articles in Engineering

Development Of Nucleic Acid Diagnostics For Targeted And Non-Targeted Biosensing, Christopher William Smith Dec 2022

Development Of Nucleic Acid Diagnostics For Targeted And Non-Targeted Biosensing, Christopher William Smith

Legacy Theses & Dissertations (2009 - 2024)

The field of nucleic acid technology is rapidly expanding with new impactful discoveriesbeing made each year. Starting from the discovery of the double-helix structure, cloning, gene editing, polymerase chain reaction (PCR), CRISPR technology, and even the late mRNA vaccines; nucleic acid technology is at the forefront of improving medicine. Nucleic acid technology is extremely versatile due to its easy programmability, automated cheap synthesis, and even its catalog for numerous chemical modifications that can be used to alter structure stability. For example, the number of permutations that can be made with DNA just by altering the code for adenine (A), cytosine …


Development Of The Assessment Of Clinical Prediction Model Transportability (Apt) Checklist, Sean Chonghwan Yu Aug 2022

Development Of The Assessment Of Clinical Prediction Model Transportability (Apt) Checklist, Sean Chonghwan Yu

McKelvey School of Engineering Theses & Dissertations

Clinical Prediction Models (CPM) have long been used for Clinical Decision Support (CDS) initially based on simple clinical scoring systems, and increasingly based on complex machine learning models relying on large-scale Electronic Health Record (EHR) data. External implementation – or the application of CPMs on sites where it was not originally developed – is valuable as it reduces the need for redundant de novo CPM development, enables CPM usage by low resource organizations, facilitates external validation studies, and encourages collaborative development of CPMs. Further, adoption of externally developed CPMs has been facilitated by ongoing interoperability efforts in standards, policy, and …


Hyperspectral Image Analysis Of Food For Nutritional Intake, Shirin Nasr Esfahani Aug 2022

Hyperspectral Image Analysis Of Food For Nutritional Intake, Shirin Nasr Esfahani

UNLV Theses, Dissertations, Professional Papers, and Capstones

The primary object of this dissertation is to investigate the application of hyperspectral technology to accommodate for the growing demand in the automatic dietary assessment applications. Food intake is one of the main factors that contribute to human health. In other words, it is necessary to get information about the amount of nutrition and vitamins that a human body requires through a daily diet. Manual dietary assessments are time-consuming and are also not precise enough, especially when the information is used for the care and treatment of hospitalized patients. Moreover, the data must be analyzed by nutritional experts. Therefore, researchers …


Predicting The Progression Of Diabetes Mellitus Using Dynamic Plantar Pressure Parameters, Mathew Sunil Varre May 2022

Predicting The Progression Of Diabetes Mellitus Using Dynamic Plantar Pressure Parameters, Mathew Sunil Varre

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Diabetic peripheral neuropathy is one of the common complications of type-2 diabetes mellitus (DM). Changes in the intrinsic plantar tissue coupled with repetitive mechanical loads and loss of sensation may lead to foot related complications (skin break down, ulcerations, and amputations) in persons with neuropathy if left untreated. The purpose of this dissertation was to stratify individuals with pre-diabetes, diabetes with and without neuropathy using dynamic plantar pressure parameters during walking, using machine learning algorithms.Methods: Plantar pressure data was collected from one hundred participants during walking with pressure measuring insoles fixed between the feet and thin socks. Simultaneously high-definition …


Seabem: An Artificial Intelligence Powered Web Application To Predict Cover Crop Biomass, Aime Christian Tuyishime, Andrea Basche Mar 2022

Seabem: An Artificial Intelligence Powered Web Application To Predict Cover Crop Biomass, Aime Christian Tuyishime, Andrea Basche

Honors Theses

SEABEM, the Stacked Ensemble Algorithms Biomass Estimator Model, is a web application with a stacked ensemble of Machine Learning (ML) algorithms running on the backend to predict cover crop biomass for locations in Sub-Saharan. The SEABEM model was developed using a previously developed database of crop growth and yield that included site characteristics such as latitude, longitude, soil texture (sand, silt, and clay percentages), temperature, and precipitation. The goal of SEABEM is to provide global farmers, mainly small-scale African farmers, the knowledge they need before practicing and benefiting from cover crops while avoiding the expensive and time-consuming operations that come …