Engineering Commons^™

Runoff And Erosion Following Field Application Of Beef Cattle Manure And Compost, John E. Gilley, Bahman Eghball

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Manure or compost from beef cattle feedlots can be excellent sources of nutrients and organic matter when added to soils. This study was conducted to determine the effect of a single application of manure and compost on runoff and erosion under no-till and tillage conditions. Tillage consisted of a single disking operation up and down the slope on a Sharpsburg soil which was cropped to grain sorghum or wheat the previous season. Manure and compost were applied at rates required to meet corn fertility requirements. Additional experimental treatments included the application of inorganic fertilizer and an untreated check. The addition …

Development Of A Practical And Effective Technique To Determine The Complete Level Of Autonomic Neural Activity During Stress, Vikki Hazelwood

Theses

Clinical evidence exists to suggest that an individual's level of stress contributes to the state of many physiological and psychological disorders, The autonomic nervous system, by adjusting parasympathetic and sympathetic activity, is attributed with the control over an individual's level of neural stress. Therefore, it is desired to develop a better and quantitative understanding of the stress! autonomic system mechanism.

Previous work has been done to gain a partial understanding of such activity. The primary objective for this study is to complement and advance the previous work by determining whether there is other physiological data which could reveal more about …

Mathematical Model Of Human Sit-To-Stand And Stand-To-Sit Motion Analysis, Jayeshkumar Gandhi

Theses

In designing a device for an amputee, it is important to find those underlying principles which determine the normal human sit-to-stand task. For this purpose we have developed a mathematical model of human sit-to-stand movement, which it is possible to predict the minimum mechanical energy consumption to move from the sit-to-stand position.

To the best of author's knowledge, this thesis represents the first time that the periodic motion of stand-to-sit and sit-to-stand movements have been mathematically modeled by a simple mechanical system. A complex model, such as the one used by Seireg and Arvikar (1973) [1] that contained 31 muscles …

Quantitative Estimation Of Heparin Content On Biological Pericadium Tissue Using In Vitro Anti-Factor Xa Assay, Jean-Claude Simeon

Theses

Shelhigh Inc. (Millburn, NJ) has developed a new heparin binding technique to biological tissues. The technique seems to bind heparin to tissues in a more permanent fashion. Shelhigh's heparinized biological tissues are intended for use in long term implants. This investigation was undertaken to assess whether heparin leaching is prevalent when tissues are quarantine for long shelflife at room temperature, whether tissues maintained thromboresistance properties when in contact with plasma and to estimate heparin content of the tissues.

The study used anti-factor Xa assaying methods: clotting time and chromogenic factor Xa sensitive substrate in order to fulfill the aforementioned objectives. …

Quantification Of Mitral Regurgitation With Mr Phase-Velocity Mapping Using A Control Volume Method, George P. Chatzimavroudis, John N. Oshinski, Roderic I. Pettigrew, Peter G. Walker, Robert H. Franch, Ajit P. Yoganathan

Chemical & Biomedical Engineering Faculty Publications

Reliable diagnosis and quantification of mitral regurgitation are important for patient management and for optimizing the time for surgery. Previous methods have often provided suboptimal results. The aim of this in vitro study was to evaluate MR phase-velocity mapping in quantifying the mitral regurgitant volume (MRV) using a control volume (CV) method. A number of contiguous slices were acquired with all three velocity components measured. A CV was then selected, encompassing the regurgitant orifice. Mass conservation dictates that the net inflow into the CV should be equal to the regurgitant flow. Results showed that a CV, the boundary voxels of …

Multidirectional Ecg Coherent Optimal Timing Of Defibrillation Shocks, Abhijit R. Patwardhan, Fabio M. Leonelli

Biomedical Engineering Faculty Patents

A method for of delivering a defibrillation shock to a heart at an optimal time to stop ventricular fibrillation which involves obtaining an electrocardiogram of a heart in at least two directions, determining a time-coherency of the electrocardiogram based upon each of the at least two directions, and computing a tracking function from the time-coherency. An optimal time to apply a defibrillation shock to the heart is determined by locating a local maximum on the tracking function. The method utilizes spacia characteristics of the ventricular fibrillation. The method can be incorporated into implantable cardioverter defibrillators utilizing existing hardware technology.

Cryptococcus Neoformans Chemotyping By Quantitative Analysis Of H-1 Nuclear Magnetic Resonance Spectra Of Glucuronoxylomannans With A Computer-Simulated Artificial Neural Network, Robert Cherniak, Homayoun Valafar, Laura C. Morris, Faramarz Valafar

Faculty Publications

The complete assignment of the proton chemical shifts obtained by nuclear magnetic resonance (NMR) spectroscopy of de-O-acetylated glucuronoxylomannans (GXMs) from Cryptococcus neoformanspermitted the high-resolution determination of the total structure of any GXM. Six structural motifs based on an α-(1→3)-mannotriose substituted with variable quantities of 2-O-β- and 4-O-β-xylopyranosyl and 2-O-β-glucopyranosyluronic acid were identified. The chemical shifts of only the anomeric protons of the mannosyl residues served as structure reporter groups (SRG) for the identification and quantitation of the six triads present in any GXM. The assigned protons for the mannosyl residues resonated at clearly …

Pulmonary Disposition Of Lipophilic Amine Compounds In The Isolated Perfused Rabbit Lung, Said H. Audi, Christopher A. Dawson, John H. Linehan, Gary S. Krenz, S. B. Ahlf, David L. Roerig

Biomedical Engineering Faculty Research and Publications

We measured the pulmonary venous concentration vs. time curves for [³H]alfentanil, [¹⁴C]lidocaine, and [³H]codeine after the bolus injection of each of these lipophilic amine compounds (LAC) and a vascular-reference indicator (fluorescein isothiocyanate-dextran) into the pulmonary artery of isolated perfused rabbit lungs. A range of flows and perfusate albumin concentrations was studied. To evaluate the information content of the data, we developed a kinetic model describing the pulmonary disposition of these LAC that was based on indicator dilution theory, and we sought a robust approach for interpreting the estimated model parameters. We found that the …

Method For Reducing The Generation Of Wear Particulates From An Implant, David A. Pienkowski, Kwon-Yong Lee

Biomedical Engineering Faculty Patents

A method is provided for reducing the amount of wear particulates generated by a total joint orthopaedic implant. The implant consists of two matched articulating components wherein at least one of the components is made of polymer or other material with similar physical properties. The method includes the steps of placing the total joint orthopaedic implant in a fluid bath and articulating the implant in the fluid bath for at least 1,000 cycles. The articulation may be performed in three stages. In the first, the implant is articulated under a load of substantially 0.1-500 Newtons with sliding speeds of substantially …

Current Concepts Review - Corrosion Of Metal Orthopaedic Implants, Joshua J. Jacobs, Jeremy L. Gilbert, Robert M. Urban

Biomedical and Chemical Engineering - All Scholarship

No abstract provided.

Tissue Engineering: At The Interface Between Engineering, Biology And Medicine, Brenda Ogle, Priti Gairola, Jodi Balik, Daniel L. Mooradian

Journal of the Minnesota Academy of Science

No abstract provided.

Multiresolution Detection Of Spiculated Lesions In Digital Mammograms, Sheng Liu, Charles F. Babbs, Edward Delp

Weldon School of Biomedical Engineering Faculty Publications

In this paper we present a novel multiresolution scheme for the detection of spiculated lesions in digital mammograms. First, a multiresolution representation of the original mammogram is obtained using a linear phase nonseparable 2-D wavelet transform. A set of features is then extracted at each resolution in the wavelet pyramid for every pixel. This approach addresses the difficulty of predetermining the neighborhood size for feature extraction to characterize objects that may appear in different sizes. Detection is performed from the coarsest resolution to the finest resolution using a binary tree classifier. This top-down approach requires less computation by starting with …

Production Of Ethers Of Gycerol From Crude Glycerol: The By-Product Of Biodiesel Production, Hossein Noureddini, W. R. Dailey, B. A. Hunt

Papers in Biomaterials

Methyl esters of fatty acids (also known as biodiesel), made from the transesterification of vegetable oils and animal fats with methanol, have shown a lot of promise as alternative diesel fuels. Glycerol is the inevitable by-product of the transesterification process. While there are existing markets for glycerol, a significant increase in availability of glycerol, resulting from the expanded use of vegetable oils and animal fats, would destabilize the glycerol market. Direct addition of glycerol to the fuel is not possible, however, derivatives of glycerol such as ethers have potential for use as additives with biodiesel, diesel or biodiesel-diesel blends. In …

Design Of Tapered Augers For Uniform Unloading Particulate Material From Rectangular Cross-Section Containers, M. S. Burr, Michael F. Kocher, David D. Jones

Department of Agricultural and Biological Systems Engineering: Faculty Publications

The design equation for an auger to provide uniform unloading of particulate material from a container with a rectangular cross-section (Jones and Kocher, 1995) was revised to account for the minimum flighting height that could effectively unload particles with a known average smallest diameter. A minimum flighting height that was about 64% of the average smallest diameter of the particles was experimentally determined to obtain mean slopes of the top surface of the material not significantly different from zero for screened soybeans. A linear taper that best fit the square root curve for the inside diameter of the auger was …

Biodiesel Fuel From Animal Fat. Ancillary Studies On Transesterification Of Beef Tallow, Fangrui Ma, L. Davis Clements, Milford Hanna

Nebraska Center for Biotechnology: Faculty and Staff Publications

Transesterification of beef tallow was investigated. The solubility of ethanol in beef tallow was much higher than that of methanol. At 100 °C the solubility of methanol was 19% (w/w). The solubility of ethanol in beef tallow reached 100% (w/w) at about 68 °C. For the distribution of methanol between beef tallow methyl esters (BTME) and glycerol, the percentage of total methanol in the glycerol phase was higher than that in the fatty acid methyl ester (FAME) phase in a simulated system at room temperature. At 65-80 °C, however, the percentage of total methanol in FAME (60% (w/w)) was higher …

Relationships Among Grain Sorghum Quality Factors, Roberto A. Buffo, Curtis L. Weller, Anne M. Parkhurst

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Correlations among grain sorghum quality factors (proximate composition, physical properties, and water absorption properties) were evaluated. Samples of 46 commercial hybrids (24 and 22 from crop years 1993 and 1994) were analyzed for starch, protein, crude free fat, test weight, absolute density, 1,000 kernel weight, percent kernel abraded, water absorption index, initial water absorption rate, and moisture saturation point. Test weight, absolute density, and percent kernel abraded were positively correlated among themselves (r > 0.5). Protein was negatively correlated with both test weight and absolute density (r < -0.5), while moisture saturation point showed negative correlations with test weight, absolute density, 1,000 kernel weight, and percent kernel abraded (r < -0.4). Principal component factor analysis through the covariance matrix explained 95% of the total variation of quality factors among hybrids (two factors), and, through the correlation matrix, 85% of the total variation (five factors). Water absorption rate decreased with increasing starch content of grain sorghum kernels as water absorption rate increased and amount of water for saturation decreased with softening of kernels.

Opto-Electronic Sensor System For Rapid Evaluation Of Planter Seed Spacing Uniformity, Michael F. Kocher, Yubin Lan, Changhe Chen, John A. Smith

Department of Agricultural and Biological Systems Engineering: Faculty Publications

An opto-electronic seed spacing evaluation system that measured time intervals between seeds and detected front-to-back location of seed drop events relative to the planter was used to rapidly determine planter seed spacing uniformity in the laboratory. The seed detection sensor for the opto-electronic system consisted of a rectangular photogate with 24 phototransistors receiving light beams from 24 LEDs opposite to them. The system also included circuitry to interface the photogate with a digital I/O board in a personal computer. The opto-electronic system was tested with three planter configurations. During the tests, the photogate was positioned beneath the seed drop tube …

Sensory Changes In Adults With Unilateral Transtibial Amputation, Judith B. Kosasih, Barbara Silver-Thorn

Biomedical Engineering Faculty Research and Publications

The purpose of this study was to describe the sensory changes in adults with unilateral transtibial amputation

(TTA), as any loss of sensation may have significant impact on the successful use of a prosthesis. Sensory modalities of light touch, deep pressure, vibration, and superficial pain (pinprick) were examined on the residual and contralateral limbs of 16 veterans with TTA. Six subjects demonstrated normal sensation on the contralateral limb and impaired sensation of superficial pain, vibration, and/or light touch on the residual limb. Superficial pain was the most frequently impaired sensation, and vibration and superficial pain sensation appeared to be age-dependent, …

Controlled Environment Potentiostat To Study Solid-Aqueous Systems, R A. Petrie, P. R. Grossl, Ronald C. Sims

Biological Engineering Faculty Publications

We designed a redox apparatus that controls electropotenial (Eh), pH, and temperature. The apparatus is fully automated and can be assembled from equipment found in most soil analytical laboratories. The reactor can maintain environmental conditions used to evaluate the chemical fate of contaminants under natural conditions (natural attenuation) or adjust them to a new steady state to evaluate the effect of engineered remediation on a subsurface system. It can operate within a wide range of redox potential values (−400 to 400 mV) and at any pH value. The stability and accuracy of the instrument was tested by performing Eh-pH titrations …

Implant Having Reduced Generation Of Wear Particulates, David A. Pienkowski

Biomedical Engineering Faculty Patents

A method is provided for reducing the amount of wear particulates generated by a total joint orthopaedic implant. The implant consists of two matched articulating components. The method includes the steps of placing the total joint orthopaedic implant in a fluid bath and articulating the implant in the fluid bath for at least 1,000 cycles. The articulation may be performed in three stages. In the first, the implant is articulated under a load of substantially 0.1-500 Newtons with sliding speeds of substantially 0.01-0.5 meters per second. During a second stage the articulation takes place under a load of substantially 200-2,500 …

Sediment Movement Within A Strip Intercropping System, John E. Gilley, L. A. Kramer, R. M. Cruse, A. Hull

Department of Agricultural and Biological Systems Engineering: Faculty Publications

This study was conducted to identify sediment movement within a strip intercropping system in southwestern Iowa during the third year of a three-year crop rotation. Soil loss, resulting from the application of simulated rainfall to a Monona silt loam soil, was measured from individual corn (Zea mays L.), soybean (Glycine max (L.) Merr), and winter wheat (Triticum aestivum L.) strips, and from multiple strips which included all three crops. Because of the crop rotation and residue management procedures, used at the study site, a substantial amount of surface cover and vegetative mass was present on each of …

Process For Producing Biodiesel Fuel With Reduced Viscosity And A Cloud Point Below Thirty-Two (32) Degrees Fahrenheit , Hossein Noureddini

Papers in Biomaterials

Triglycerides are reacted in a liquid phase reaction with methanol and a homogeneous basic catalyst. The reaction yields a spatially separated two phase result with an upper located non-polar phase consisting principally of non-polar methyl esters and a lower located phase consisting principally of glycerol and residual methyl esters. The glycerol phase is passed through a strong cationic ion exchanger to remove anions, resulting in a neutral product which is flashed to remove methanol and which is reacted with isobutylene in the presence of a strong acid catalyst to produce glycerol ethers. The glycerol ethers are then added back to …

Electrophysiologic Studies Of Hypothalamic Adenosine-5'-Triphosphate-Sensitive Potassium Channels, Dinora Hernandez

Theses

Of particular interest in this study were the electrical phenomena involving currents from the ATP sensitive K channel in isolated hypothalamic ventromedial nucleus (VMN) neurons. These neurons may play an important role in the glucose-sensing system of the body. Rat VMN neurons were isolated. For neuronal isolation, the proteolytic enzyme pronase was used. However, pronase was too harsh. The use of papain, another proteolytic enzyme, led to better neuronal morphology. The perforated patch clamp technique was used to gain access to the cell's interior. For membrane pore formation, nystatin was used; but seal formation was difficult. Amphotericin was used instead, …

Determination Of Effects Of Stress On Polymeric Ankle-Foot Due To Weight Change: Experimental Stress Analysis, Lin Yu Wang

Theses

Ankle-Foot Orthoses (AFOs) are devices that assist patients who sustained an abnormal motion at the ankle joint of the foot due to traumatic injury and stroke, etc. The objective of this project is to determine the stress patterns in AFOs under different loading conditions such as weights and genders. Thus, the location of failure can be predicted, and a redesign process can be developed. Furthermore, those experimental results will be used to verify the results obtained from the previous Finite Element Analysis (FEA) ^[11,10]. Results from the experiment showed a significant stress change due to load change. This stress …

Using Heart Variability To Measure The Effects Of Manual Medicine On Autonomic Activity, Michael Zullow

Theses

A pilot study was performed to test the theory that manual medicine techniques known as the CV4 (compression of fourth cerebral ventricle) maneuver and a sacral hold/iliac bridge hold combination increase parasympathetic activity. Manual medicine techniques are widely practiced by Doctors of Osteopathy and Chiropractors to treat physical and mental health problems. Those who have received manual therapy have reported to experience less pain, better mobility, and a greater feeling of relaxation. To help us learn about the effects of manual therapy, autonomic activity was measured scientifically rather than subjectively in this study by monitoring respiration rate and heart rate, …

Testing Of A Water Loss Distribution Model For Moving Sprinkler Systems, Allen L. Thompson, Derrel L. Martin, John M. Norman, Judy A. Tolk, James R. Gilley, Arlan D. Schneider

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Field water balance measurements using monolithic lysimeters were used in validating the Cupid-DPE model for predicting water loss partitioning during sprinkler irrigation from a moving lateral system fitted with impact sprinklers and spray nozzles. The model combines equations governing water droplet evaporation and droplet ballistics with a comprehensive plant-environment energy balance model. Comparisons indicate good agreement between measured and modeled transpiration, and the measured and modeled soil evaporation during the day of irrigation. Total predicted evapotranspiration during the day of irrigation was greater than measured totals using the monolithic lysimeters. However, part of this difference was because the lysimeters could …

Runoff, Erosion, And Soil Quality Characteristics Of A Former Conservation Reserve Program Site In Southwestern Oklahoma, John E. Gilley, John W. Doran, Thanh H. Dao

Department of Agricultural and Biological Systems Engineering: Faculty Publications

This study was conducted to measure runoff, erosion, and soil quality characteristics of a site in southwestern Oklahoma the first year following conversion from the Conservation Reserve Program (CRP). Treatments included undisturbed CRP, Old World bluestem (Bothriochlora ischaemum L.), no-till wheat (Triticum aestivum L.) and conservation-till wheat. Significant differences in surface cover were found between each of the experimental treatments, with values ranging from 100% on the undisturbed CRP site to 42% for the conservation-till treatment. No significant difference in runoff was found among the various experimental treatments. The Old World bluestem and winter wheat treatments had only …

Water Transport And The Distribution Of Aquaporin-1 In Pulmonary Air Spaces, Richard M. Effros, C. Darin, Elizabeth R. Jacobs, R. A. Rogers, Gary S. Krenz, E. E. Schneeberger

Biomedical Engineering Faculty Research and Publications

Recent evidence suggests that water transport between the pulmonary vasculature and air spaces can be inhibited by HgCl₂, an agent that inhibits water channels (aquaporin-1 and -5) of cell membranes. In the present study of isolated rat lungs, clearances of labeled (³HOH) and unlabeled water were compared after instillation of hypotonic or hypertonic solutions into the air spaces or injection of a hypotonic bolus into the pulmonary artery. The clearance of ³HOH between the air spaces and perfusate after intratracheal instillation and from the vasculature to the tissues after pulmonary arterial injections was invariably greater …

Interferon Gamma (Ifn-Gamma) Is Necessary For The Genesis Of Acetylcholine Receptor-Induced Clinical Experimental Autoimmune Myasthenia Gravis In Mice., Balaji Balasa, Caishu Deng, Jae Lee, Linda M. Bradley, Dyanna K. Dalton, Premkumar Christadoss, Nora Sarvetnick

Journal Articles: Regenerative Medicine

Experimental autoimmune myasthenia gravis (EAMG) is an animal model of human myasthenia gravis (MG). In mice, EAMG is induced by immunization with Torpedo californica acetylcholine receptor (AChR) in complete Freund's adjuvant (CFA). However, the role of cytokines in the pathogenesis of EAMG is not clear. Because EAMG is an antibody-mediated disease, it is of the prevailing notion that Th2 but not Th1 cytokines play a role in the pathogenesis of this disease. To test the hypothesis that the Th1 cytokine, interferon (IFN)-gamma, plays a role in the development of EAMG, we immunized IFN-gamma knockout (IFN-gko) (-/-) mice and wild-type (WT) …

Model Of Flexural Fatigue Damage Accumulation For Cortical Bone, L. V. Griffin, J. C. Gibeling, R. B. Martin, V. A. Gibson, S. M. Stover

Biomedical Engineering

Analytical models that predict modulus degradation in cortical bone subjected to uniaxial fatigue loading in tension and compression are presented. On the basis of experimental observations, damage was modeled as self-limiting for tension but not for compression. These mechanistic uniaxial damage models were then developed into a model for flexural fatigue of cortical bone based on laminated beam theory. The unknown coefficients in the uniaxial damage models were obtained by successfully fitting the resulting equations to uniaxial fatigue data from the literature on human cortical bone in tension and compression. Then, the predictions of the flexural model for the behavior …