Science and Mathematics Education Commons^™

Project Guidelines, Sarah O'Leary-Driscoll

Research Project

No abstract provided.

Pt. 1: Research Question & Background, Sarah O'Leary-Driscoll

Research Project

No abstract provided.

Dna Timeline And Poster Project, Sarah O'Leary-Driscoll

Genomics: Past & Future

The DNA timeline goes through many of the major discoveries that have driven our understanding of genetics since Mendel. Pick two scientists and create a PowerPoint slide poster (to be printed out on regular printer sized paper) that covers the following:

Database/Resource Acronyms, Sarah O'Leary-Driscoll

Course Information

No abstract provided.

Poster 7: Importance Of Protein Structure Prediction, Michael Qian '16, Sarah Dovgin '16, Esther Chung '16

Protein Folding & Structure Prediction Posters

Initially, drugs were discovered by either chance or by trial and error through screening methods. Because scientists did not have the ability to model protein structures, drug discovery was a very expensive process. Currently, researchers are working on technologies to determine protein ligands and potential drugs through the usage of predicted protein structures.

Poster 1: Protein Functions And Relationships Between Structure And Function, Mara Cardona '16, Max Shramuk '16

Protein Folding & Structure Prediction Posters

No abstract provided.

Poster 6: Chaperone Proteins, Grace Carlberg '16, Andy Xu '16, Andrew Adams '16

Protein Folding & Structure Prediction Posters

No abstract provided.

Readings On Current Biology: Bibliography, Imsa Biology Team

Nature of Science

No abstract provided.

What Is Bioinformatics?, Sarah O'Leary-Driscoll

Course Information

Bioinformatics has evolved into a full-fledged multidisciplinary subject that integrates developments in information and computer technology as applied to Biotechnology and Biological Sciences. Bioinformatics uses computer software tools for database creation, data management, data warehousing, data mining and global communication networking. Bioinformatics is the recording, annotation, storage, analysis, and searching/retrieval of nucleic acid sequence (genes and RNAs), protein sequence and structural information. This includes databases of the sequences and structural information as well methods to access, search, visualize and retrieve the information. Bioinformatics concern the creation and maintenance of databases of biological information whereby researchers can both access existing information …

Science & Spaghetti Monsters: Understanding The Nature Of Scientific Knowledge & Research, Sarah O'Leary-Driscoll

Nature of Science

What is science?

When students are asked to define science, many of them define science as “a body of knowledge gained by performing experiments.”

A more appropriate definition, however, is that “Science is … a process of inquiry aimed at building a testable body of knowledge open to rejection or confirmation” (Shermer, 2005).

There are three important points that this definition makes:

Glossary Of Bioinformatics Terms, National Human Genome Research Institute

Course Information

No abstract provided.

Comprehensive Course Syllabus, Sarah O'Leary-Driscoll

Course Information

The bioinformatics seminar is focused on developing an understanding of the principles behind genomic analyses, developing skills using the different available bioinformatics programs, and becoming aware of the past developments and current research avenues that are benefited by these types of analyses.

Obtaining Genomic Sequence Practice, Sarah O'Leary-Driscoll

Introduction to NCBI

No abstract provided.

3: Genomics: Past & Future Bibliography, Sarah O'Leary-Driscoll

Genomics: Past & Future

No abstract provided.

Future Of Genomics: Presentations, Sarah O'Leary-Driscoll

Genomics: Past & Future

In his testimony to a House of Representatives sub-committee on health, director of the National Human Genome Research Institute, Francis S. Collins, said that the future of genomics had three main focal points:

"Genomics to Biology: The human genome sequence provides foundational information that now will allow development of a comprehensive catalog of all of the genome's components, determination of the function of all human genes, and deciphering of how genes and proteins work together in pathways and networks.

Genomics to Health: Completion of the human genome sequence offers a unique opportunity to understand the role of genetic factors in …

Primer Design Activity, Sarah O'Leary-Driscoll

Primer Design

No abstract provided.

Pt. 2: Presentation / Paper Guidelines, Sarah O'Leary-Driscoll

Research Project

The presentations for your project should follow the same format that the paper would, but in a much more abbreviated form, aim for 5-7 minutes.

2: Sequence Alignment Practice Activity, Sarah O'Leary-Driscoll

Sequence Alignments

Now that you have learned how to do the four basic sequence alignments (Pairwise and Multiple for both nucleotide and protein sequences) select a gene/protein, it may be one that you've used before, and run each of these alignments.

Alignment Information, Sarah O'Leary-Driscoll

Sequence Alignments

Pairwise DNA alignment is frequently used to identify similar regions that will show how two sequences have functional or structural similarities. It can also be used to show how exons and introns change between different sequences and whether they have an effect on the final structure of the RNA after the DNA is processed within a cell.

Alignment Outline, Sarah O'Leary-Driscoll

Sequence Alignments

No abstract provided.

Sequencing Techniques: A Comparison Assignment, Sarah O'Leary-Driscoll

Sequencing & Genome Mining

With your partner, create some sort of visual (table, map, chart, other, ask me!) that compares the main types of sequencing that we discussed, as well as two of the techniques considered 'next generation'.

Poster 2: Primary Structure, Max Shramuk '16, Mara Cardona '16

Protein Folding & Structure Prediction Posters

No abstract provided.

Poster 3: Secondary Structure, Michael Qian '16, Sarah Dovgin '16, Esther Chung '16

Protein Folding & Structure Prediction Posters

No abstract provided.

Poster 4: Tertiary Structure, Grace Carlberg '16, Andy Xu '16, Andrew Adams '16

Protein Folding & Structure Prediction Posters

When proteins form polypeptide chains, they form primary structure - their amino acid sequence - secondary structure - their local shapes - and tertiary structure - their global fold and shape. Tertiary structure and its prediction are of vital importance to the biology community because of its importance for manipulating gene expression, cell-wide processes, and more. Because of the innumerable possibilities for even a simple primary structure protein, prediction is incredibly difficult. As bioinformatics technologies advance, though, our understanding of tertiary folding advances.

Poster 5: Quaternary Structure, Arun Arjunakani '16, Joseph Jagusah '16

Protein Folding & Structure Prediction Posters

No abstract provided.

Poster 8: Predicting Structure: Current Techniques And Challenges, Arun Arjunakani '16, Joseph Jagusah '16

Protein Folding & Structure Prediction Posters

No abstract provided.

Essential Questions, Imsa Biology Team

Evolution

In order to understand the current state of biological life and how it has changed over time, the following questions must be addressed:

Evidence Of Evolution 1: Structures, Imsa Biology Team

Evolution

In order to investigate linage, evolutionary history, and common ancestry, you need to be familiar with the following structures.

Mechanisms And Speciation 1: The Modern Synthesis, Imsa Biology Team

Evolution

The Modern Synthesis or Synthetic Theory of Evolution is an explanation of evolution that is based on modern genetic principles. According to the Modern Synthesis (a.k.a. Neo-Darwinism):

Evolution Practice 1, Imsa Biology Team

Evolution

Answer the following questions using information from the handouts, and examples from the LAB