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Full-Text Articles in Other Education

Infiltration Of Immune Cells And Lipid Nanoparticle-Mediated Drug Delivery In A Skin Cancer Model, Aynur Sanem Yilmaz Nov 2024

Infiltration Of Immune Cells And Lipid Nanoparticle-Mediated Drug Delivery In A Skin Cancer Model, Aynur Sanem Yilmaz

USF Tampa Graduate Theses and Dissertations

Melanoma, the deadliest form of skin cancer, is notorious for its rapid mutation rate and high potential for metastasis, making effective treatment particularly challenging. Immunotherapy has emerged as a significant advancement in melanoma therapy, leveraging the immune system to target and eliminate cancer cells. These achievements have motivated further investigation into immune system-based strategies for this aggressive cancer. Cell-based drug delivery has been primarily achieved by either using immune cells as direct carriers for therapeutics or by employing active molecules through drug delivery systems, most often nanoparticles. While immune cells exhibit innate tumor-homing abilities, they face challenges such as limited …


Selective Pericyte Recruitment To Ec-Lined Tubes, Vessel Assembly Enhancement Through Pericyte Timp-3 Induction, And Pericyte Tbx2 In Capillary Formation And Maturation, Ksenia Marilyn Yrigoin Kaluguina Oct 2024

Selective Pericyte Recruitment To Ec-Lined Tubes, Vessel Assembly Enhancement Through Pericyte Timp-3 Induction, And Pericyte Tbx2 In Capillary Formation And Maturation, Ksenia Marilyn Yrigoin Kaluguina

USF Tampa Graduate Theses and Dissertations

Capillaries, the smallest blood vascular networks, are formed by narrow and elongated endothelial cell (EC)-lined tubes with associated pericytes anchored to the abluminal tube surface. Our laboratory demonstrated that dynamic interactions between ECs and pericytes during capillary tube network assembly are required for basement membrane matrix deposition and maturation. We have also shown that key EC-derived factors promote pericyte recruitment, proliferation, and pericyte-induced basement membrane formation during capillary assembly. In the first section, we aim to identify if vascular smooth muscle cells (VSMCs) respond to the same factors and have the same invasive ability as pericytes since they are both …


Revision Strategies And Academic Socialization Of Multilingual Graduate Students, Sean E. Farrell Oct 2024

Revision Strategies And Academic Socialization Of Multilingual Graduate Students, Sean E. Farrell

USF Tampa Graduate Theses and Dissertations

Research suggests that revision is a complex practice guided by a variety of factors; however, the nature of the relationship between these factors and the revisions themselves, along with how the revision process contributes to academic socialization, remains understudied. A more comprehensive understanding of revision can lead to a deeper understanding of the support that will be most effective for multilingual graduate students. This study thus aims to determine (1) what revision strategies multilingual graduate students use, (2) what factors mediate these strategies, and (3) the extent to which these revisions index a shift in academic socialization. To answer these …


Modification Of 2d Chalcogenides By Metal Vapor Reaction, Vimukthi Viraj Perera Pathirage Sep 2024

Modification Of 2d Chalcogenides By Metal Vapor Reaction, Vimukthi Viraj Perera Pathirage

USF Tampa Graduate Theses and Dissertations

The interest in studying 2D materials has increased over time due to their unique physical and chemical properties, which have the potential to lead to numerous applications in technology. For instance, their small size makes them useful for technology that requires greater efficiency, faster processing speeds, and less physical space. Transition metal dichalcogenides (TMDs) are a type of 2D material that is composed of one transition metal layer sandwiched between two chalcogen layers. The study of TMDs is of significant importance due to their layer-dependent properties and the fact that different phases exhibit distinct properties, including electronic properties. However, it …


Development And Initial Validation Of The Musical Discrimination And Styles Task: Measuring Children And Adolescent Music Aptitude And Achievement, Dawn R. Mitchell White Jul 2024

Development And Initial Validation Of The Musical Discrimination And Styles Task: Measuring Children And Adolescent Music Aptitude And Achievement, Dawn R. Mitchell White

USF Tampa Graduate Theses and Dissertations

This dissertation had two purposes: 1) to create and document the development of a new music achievement test entitled the Musical Discrimination and Styles Task (MDAST), and 2) to describe the strength of the evidence supporting the validity and reliability of this new developmentally appropriate music aptitude and achievement instrument. I created a theoretical framework based on 1) the cognitive theory of child development of Jean Piaget, 2) the phase model of artistic development by David Hargreaves, and 3) the theoretical models of music discrimination, audiation, and music achievement by Edwin Gordon. The MDAST’s design assessed students’ abilities to evaluate …


Breaking The Sound Barrier: Strategies For Reducing The Educational Debt In Underserved School Bands, Alfonzo V. Kimbrough Jul 2024

Breaking The Sound Barrier: Strategies For Reducing The Educational Debt In Underserved School Bands, Alfonzo V. Kimbrough

USF Tampa Graduate Theses and Dissertations

The purpose of this multiple explanatory case study was to investigate the preparation of underserved school band programs for a Music Performance Assessment (MPA). Specifically, I examined racial, economic, and social inequalities, which are well documented in the research literature, and the related achievement gaps of underserved public school bands. Using Ladson-Billings’ four pillars of educational debt, a replication approach highlighted four cases as a small sample of the success rate of Title I school bands scoring a Superior at an MPA contest. I compared how contextual issues impacted the four band directors at these schools in preparations for their …


Migrant Advocates' Perceptions Of School-Based Collaboration, Michael Young Jul 2024

Migrant Advocates' Perceptions Of School-Based Collaboration, Michael Young

USF Tampa Graduate Theses and Dissertations

Migrant farmworker students are a marginalized group with unique needs. Federal law provides funding for Migrant Farmworker Advocates who support the educational and material needs of migrant farmworker students and their families in public schools. This exploratory study examines the question, how do migrant advocates collaborate with other professionals to support their students with graduation and transitioning to post-secondary opportunities? The study analyzes this unexplored professional relationship between migrant advocates and high school personnel and how they work together to serve migrant students. Data were collected through semi-structured single subject interviews from seven current or former Title I funded Migrant …


Identification And Characterization Of Intrinsically Disordered Protein Regions, Guy Wayne Dayhoff Ii Jul 2024

Identification And Characterization Of Intrinsically Disordered Protein Regions, Guy Wayne Dayhoff Ii

USF Tampa Graduate Theses and Dissertations

This dissertation investigates protein intrinsic disorder and intrinsically disordered protein regions (IDPRs) through the development and application of advanced computational and experimental techniques. Chapter 1 provides an introduction to protein intrinsic disorder, outlining the historical context and fundamental concepts that highlight the importance of intrinsically disordered proteins (IDPs) and IDPRs in various biological processes. Chapter 2 focuses on the rapid prediction and analysis of protein intrinsic disorder. We introduce RIDAO (Rapid Intrinsic Disorder Analysis Online), a high-efficiency web-based tool that integrates multiple disorder predictors. RIDAO significantly outperforms existing predictors in computational efficiency, making it suitable for large-scale proteomic studies. We …


Data-Driven Modeling Of Calcium Homeostasis And Bioenergetics In Alzheimer’S Disease, Down’S Syndrome And Leigh’S Syndrome., Abdul Rahim Umar Jul 2024

Data-Driven Modeling Of Calcium Homeostasis And Bioenergetics In Alzheimer’S Disease, Down’S Syndrome And Leigh’S Syndrome., Abdul Rahim Umar

USF Tampa Graduate Theses and Dissertations

Disruption of Ca2+ homeostasis is implicated in the pathogenesis of several neurological conditions, including Alzheimer’s disease (AD), AD-like pathology in Down's Syndrome (DS) and Leigh’s Syndrome (LS). In astrocytes, disrupted intracellular Ca2+ signaling can compromise numerous brain functions, including synaptic transmission, neurovascular coupling, andbioenergetics. In our first project, we investigated the effects of brain extracts from AD patients on calcium signaling within cells and found that these extracts triggered a release of calcium within the cell, similar to synthetic components of amyloid beta plaques, a hallmark of AD. We developed a computational model to analyze how these changes in calcium …


Exploring Online Language Learning Activities And Intercultural Communicative Competence: Perspectives Of International Students, Moneera Abdulaziz Alsubaihi Jun 2024

Exploring Online Language Learning Activities And Intercultural Communicative Competence: Perspectives Of International Students, Moneera Abdulaziz Alsubaihi

USF Tampa Graduate Theses and Dissertations

Societies are increasingly aware of the need to connect and communicate globally. Thus, navigating diverse cultural contexts becomes critical, which necessitates intercultural competence—the skill of effective communication and understanding across cultures. As the digital age reshapes our interactions, online learning platforms have emerged as dynamic spaces that foster intercultural engagement and competency development. The purpose of this study was to explore this engagement and development through online English language activities that enhance international students' intercultural communicative competence (ICC) and language learning experience. This qualitative study aimed to provide a comprehensive understanding of international students' experiences in online English language courses, …


“It’S Not Me, It’S You:” A Critical Race Exploration Of University-Community Partnerships (Ucps) With Black Community Leadership, Christopher Ellis Matthew Darby Jun 2024

“It’S Not Me, It’S You:” A Critical Race Exploration Of University-Community Partnerships (Ucps) With Black Community Leadership, Christopher Ellis Matthew Darby

USF Tampa Graduate Theses and Dissertations

Despite the growing number of initiatives and efforts by universities to engage with their local communities, university-community partnerships (UCPs) remain complex relationships from their development to implementation—specifically, UCPs between Black communities and predominantly White institutions (PWI). However, research that centers on Black communities and their UCPs is limited. This study delves into the dynamics of UCPs with Black communities, aiming to explore and comprehend the attitudes, perceptions, and experiences from the viewpoints of both university and Black community leaders. Employing a convergent parallel mixed methods research design and utilizing Critical Race Theory (CRT) and Community-Based Educational Leadership (CBEL) to inform …


Exploring Spin Dynamics Using Time-Resolved Magneto-Optic Kerr Effect Spectroscopy, Arup Barua Jun 2024

Exploring Spin Dynamics Using Time-Resolved Magneto-Optic Kerr Effect Spectroscopy, Arup Barua

USF Tampa Graduate Theses and Dissertations

The interaction between light and matter plays a crucial role in numerous systems, including optoelectronicdevices such as Photodiode (PD), Laser diode (LD), LED, solar cells to even biological components like photosystem II, and potential upcoming quantum technologies. Light is absorbed or emitted usually at a scale smaller than a nanometer, with associated processes happening within attosecond to picosecond durations. It is known that in a vacuum, static magnetic fields do not affect light. On the other hand, the magnetic field or magnetization of a material affects the light that passes through or is reflected by the material. The magneto-optic effect …


Peritraumatic Distress And Dissociation In People With And Without Disabilities Utilizing Emergency Departments, Sydney C. Hart Jun 2024

Peritraumatic Distress And Dissociation In People With And Without Disabilities Utilizing Emergency Departments, Sydney C. Hart

USF Tampa Graduate Theses and Dissertations

To date the literature on peritraumatic distress and peritraumatic dissociation in individuals receiving emergency medical treatment has not examined people with disabilities or chronic health conditions as a specified population, despite these populations’ disproportional utilization of medical facilities and additional stressors faced in those environments. Thus, this study assessed and compared the prevalence and averages on the Peritraumatic Distress Inventory (PDI) and Peritraumatic Dissociative Experiences Questionnaire (PDEQ) in people with and without disabilities and/or chronic health conditions after Emergency Department (ED) visits. A sample of 138 participants 18 years of age or older, of which 109 reported disabilities and/or chronic …


Unveiling Ferroelectric And Multifunctional Insights In Hybrid Formate Perovskites, Abduljelili Popoola Jun 2024

Unveiling Ferroelectric And Multifunctional Insights In Hybrid Formate Perovskites, Abduljelili Popoola

USF Tampa Graduate Theses and Dissertations

Formate perovskites, denoted as AB(HCOO)3, represent a diverse group of hybrid organic-inorganic compounds, renowned for their numerous phase transitions and a wide array of properties. These properties encompass (anti)ferroelectricity, ferroelasticity, (anti)ferromagnetism, and multiferroism. Despite extensive research on these materials, a comprehensive examination of their properties across a substantial number of formate perovskites remains scarce. This scarcity stems from structural complexity of these materials, potential systematic errors arising from different measurement techniques or incomplete data. For instance, data for critical parameters like piezoelectricity, dielectricity, and elasticity tensors have been lacking.

In this study, we address these challenges by employing first-principles density …


An Investigation Of Quaternary Metal Chalcogenide Semiconductors Possessing Intrinsically Low Thermal Conductivity, Oluwagbemiga P. Ojo Jun 2024

An Investigation Of Quaternary Metal Chalcogenide Semiconductors Possessing Intrinsically Low Thermal Conductivity, Oluwagbemiga P. Ojo

USF Tampa Graduate Theses and Dissertations

Inorganic materials with unique physical properties are vital components of modern technology, from electronic devices to energy storage and conversion systems. Recent advancements in materials research and development have garnered significant interest, particularly in the realm of sustainable energy applications like thermoelectrics and photovoltaics. The development of novel materials with enhanced electronic and thermal properties has emerged as a focal point in advancing these critical applications. Furthermore, low thermal conductivity materials are sought after for technologically significant applications such as thermal barrier coatings, rewriteable data storage utilizing phase change materials and thermoelectrics. However, the current efficiency levels of materials used …


Emergent Magnetism And Hyperthermia In Phase- And Size-Tunable Iron Oxide Nanostructures, K Mudiyanselage Tharindu Supun Bandara Attanayake Jun 2024

Emergent Magnetism And Hyperthermia In Phase- And Size-Tunable Iron Oxide Nanostructures, K Mudiyanselage Tharindu Supun Bandara Attanayake

USF Tampa Graduate Theses and Dissertations

Iron oxide nanoparticles (IONPs) hold immense potential across diverse fields, from spintronics, magnetic hyperthermia to drug delivery, biodetection, and magnetic resonance imaging. Unlocking these applications hinges on our ability to tailor the magnetic properties of IONPs, and this dissertation presents novel and powerful approaches for enhancing magnetic and hyperthermic responses of multiphase iron oxide nanostructures. This is achieved by manipulating their phase volume fraction, size, and shape with a focus on the magnetic tunability of nanostructures via strategic control over structural and environmental parameters. The aforementioned has been achieved by the following three key approaches: (i) phase-tunability of iron oxide …


Effects Of Intercultural Interactions In 3d Virtual World On Efl Students’ Intercultural Communicative Competence, Foreign Language Anxiety, And Motivation, Umi H. Saidah Jun 2024

Effects Of Intercultural Interactions In 3d Virtual World On Efl Students’ Intercultural Communicative Competence, Foreign Language Anxiety, And Motivation, Umi H. Saidah

USF Tampa Graduate Theses and Dissertations

Virtual worlds (VWs) as emerging technologies have been perceived as positive by students for foreign language (FL) learning. VW affordances of presence and immersion have enabled FL researchers and practitioners to design and develop classroom-like environments in virtual settings, allowing authentic intercultural interactions from different geographical locations, in a variety of languages. This study conducted mixed methods research to deliver English lessons via an immersive 3D VW for avatar-context-avatar interactions via voice chat with a view to improving ICC necessary for effective intercultural interaction. The avatar-avatar interactions were between a native English-speaking instructor and English as a foreign language (EFL) …


Developing Cultural Humility Through The Arts: Evaluating An Arts Intervention For Healthcare Provider Leaders, Katie L. Nickel Jun 2024

Developing Cultural Humility Through The Arts: Evaluating An Arts Intervention For Healthcare Provider Leaders, Katie L. Nickel

USF Tampa Graduate Theses and Dissertations

At all levels of healthcare, providers are experiencing rising levels of professional burnout. For healthcare provider leaders, burnout is particularly critical since leaders must maintain healthy and trusting relationships with patients and their teams of healthcare professionals. This utilization-focused evaluation study explores an arts intervention program designed to promote cultural humility among healthcare providers. Increased cultural humility may provide coping tools for healthcare providers to ward off burnout. The arts intervention took place over three sessions: one at a museum, one virtual, and one at a hospital. Four types of data were collected including a quantitative pre- and post-survey, observation …


Abc It's Easy As...: Clarifying Alphabet Knowledge Development In Preschool Populations, Lauren Arielle Mckeever May 2024

Abc It's Easy As...: Clarifying Alphabet Knowledge Development In Preschool Populations, Lauren Arielle Mckeever

USF Tampa Graduate Theses and Dissertations

Alphabet Knowledge (AK) is a critical precursor to literacy development. Despite a clear linkage between AK and childhood reading and later academic success, the progression of how this skill is acquired remains unclear. Through a series of investigations, this dissertation examined the assessment and intervention of AK in preschool populations.

The first study was a systematic review to delineate aspects of AK, focusing on instructional practices, measurement techniques, and how they align. This study synthesized existing literature on AK through a systematic review of 32 studies to identify common themes related to AK definitions, instructional content, and measurement approaches. The …


Band Members’ Attitudes Toward The Queer Community And Perception Of Band As A Safe Space, Brian J. Panetta Mar 2024

Band Members’ Attitudes Toward The Queer Community And Perception Of Band As A Safe Space, Brian J. Panetta

USF Tampa Graduate Theses and Dissertations

Using Bronfenbrenner’s ecological framework of human development and Yuval-Davis’ analytical framework of belonging as a lens to explain how the band environment might cultivate positive attitudes toward the queer community, this study investigated band members’ attitudes toward the queer community and their perception of the band as a safe space. Utilizing adapted inventories with established reliability and validity, the following research questions were addressed: 1) What are queer and non-queer band members’ attitudes toward the queer community? 2) What are queer and non-queer band members’ attitudes toward the band as a safe space? 3) What differences exist between the independent …


Count Me In: A Study Of Social Validity, Positive Behavioral Interventions And Supports, And A High School, Amie Dia Davis Mar 2024

Count Me In: A Study Of Social Validity, Positive Behavioral Interventions And Supports, And A High School, Amie Dia Davis

USF Tampa Graduate Theses and Dissertations

The implementation of Positive Behavioral Interventions and Supports (PBIS) has been attributed to a decrease in office discipline referrals (ODRs) and suspensions and to increase academic performance, and engagement, as well as staff, family, and student perceptions of a safe and positive school climate. High schools have had more significant issues than elementary sites with implementing PBIS and garnering staff support due to larger faculty, staff, and student size, multi-faceted organizational culture, and the age of the students served. In addition, factors that have also been cited as inhibiting successful implementation at the high school level are lack of student …


Becoming Conscious: An Autoethnographic Study Analyzing The Relationship Between Identity And Leadership, Aaron Izzo Mar 2024

Becoming Conscious: An Autoethnographic Study Analyzing The Relationship Between Identity And Leadership, Aaron Izzo

USF Tampa Graduate Theses and Dissertations

This dissertation aims to define the connection between one’s perceptions of self and how one conceptualizes leadership. This study first conceptualized my own identity, seeking to connect my past experiences and interactions with others utilizing a term borrowed from Eastern philosophy, samskara, to see how they impact my current practice within leadership. Within the current body of research, various forms of leadership approaches, such as relational, appreciative, feminist, queer, and conscious leadership, were described and explored. What was found to be missing from the current body of work was a connection between who a person is, how they identify, and …


Going Through To Get Through: Life Histories Of Black Women In Educational Leadership, Ann Marie M. Mobley Mar 2024

Going Through To Get Through: Life Histories Of Black Women In Educational Leadership, Ann Marie M. Mobley

USF Tampa Graduate Theses and Dissertations

Black women who become school-based administrators are severely understudied in scholarly research (Lomotey, 2019). Studies suggest that Black women in the United States, who ascend into educational leadership positions, rely on professional training(s) associated with their employment and understandings accrued from inter/personal background experiences (cultural, familial) to navigate discrimination while attempting to lead. The purpose of this study was to examine how Black women use personal and professional lessons to reconcile tensions and contradictions in their administrative roles in public schools. Using a life history approach, I gathered data by interviewing seven Black women administrators (all identified as African American), …


Disability, Blackness, And Online Community: Black Twitter As Self-Narrative, Morgan S. Wilson Mar 2024

Disability, Blackness, And Online Community: Black Twitter As Self-Narrative, Morgan S. Wilson

USF Tampa Graduate Theses and Dissertations

Black disabled people, especially those with invisible disabilities, are often not included or welcomed by all in the disabled community. In addition, Black disabled individuals also face discrimination and exclusion within the Black community due to ableism. This project will be an investigation of Black disabled community and health culture in online spaces, specifically using Twitter hashtags as a starting point. This research project is about helping to write the whole story, an opportunity that my Black ancestors did not have but still demand, for our generation and those who will come after us. For this project, I conducted an …


Caring In Social Studies: An Examination Of Teacher Preparation Standards, Vanializ Agramonte Mar 2024

Caring In Social Studies: An Examination Of Teacher Preparation Standards, Vanializ Agramonte

USF Tampa Graduate Theses and Dissertations

Care is something we expect educators to demonstrate towards their students, but are theythemselves being taught the importance of care in education and prepared to enact it in their classrooms? The existing literature on care and care theory in education is limited, but shows a link between care and student success; many educators also point to anecdotal evidence of the importance of care. This study sought to examine themes of care in national standards for teacher preparation. Through the use of directed qualitative content analysis, three national teacher preparation standards (the Council for the Accreditation of Educator Preparation, the Interstate …


Forgotten Learners: An Examination Of The Experiences Of English Language Learners In Advanced Placement And International Baccalaureate Social Studies Courses, Elizabeth Rasmussen Mar 2024

Forgotten Learners: An Examination Of The Experiences Of English Language Learners In Advanced Placement And International Baccalaureate Social Studies Courses, Elizabeth Rasmussen

USF Tampa Graduate Theses and Dissertations

The number of English Language Learners (ELLs) in the United States is rapidly increasing, particularly in high schools. Although the number of ELLs is growing at a fast pace in the United States, the number of ELLs enrolled in advanced educational programming has not increased. After an in-depth review of the extant literature, it is evident that limited scholarly research on ELLs in advanced coursework exists. This is especially true in AP and IB social studies courses, where in many states where “Open Access” and “AP for All” have been adopted. This qualitative study sought to reveal the lived experiences …


Interfacial Magnetism And Anisotropy In Dirac And Weyl Semimetals, Noah Schulz Mar 2024

Interfacial Magnetism And Anisotropy In Dirac And Weyl Semimetals, Noah Schulz

USF Tampa Graduate Theses and Dissertations

Semimetals have gained intense interest recently due to their exotic magnetic and electronic properties. One of the most widely studied semimetals is graphene, a Dirac semimetal. The utilization of graphene in devices and sensors requires interfacing it with other materials, which may induce potentially strong interfacial effects. Furthermore, graphene alone does not possess magnetic order. Studying the interfacial effects between graphene and magnetic materials is therefore of great importance in the application of graphene to meet modern technological needs. Furthermore, by understanding the fundamental interfacial physics between graphene and magnetic materials, new properties can be unlocked, broadening the possible applications …


Secondary Educator Approaches To Cemetery-Based Education In Florida, Hillary M. Van Dyke Mar 2024

Secondary Educator Approaches To Cemetery-Based Education In Florida, Hillary M. Van Dyke

USF Tampa Graduate Theses and Dissertations

The purpose of this qualitative, descriptive case study is to study how teachers utilize cemeteries as a teaching space, specifically for instruction in Black history and for enacting social studies curriculum by examining the curricular and instructional strategies two educators use with historically Black cemeteries as a place of learning for students in west coastal central Florida. Conversations around what to do about the issue of historically Black cemeteries are growing in Florida, including the state dedicating resources to place-based education in cemeteries. Thus, this study is timely. A purposeful sampling strategy was used to select the two educators who …


Formulating Utopian Pasts: Time As A Coping Method For Lgbtq+ Floridians, Elise M. Kuechle Feb 2024

Formulating Utopian Pasts: Time As A Coping Method For Lgbtq+ Floridians, Elise M. Kuechle

USF Tampa Graduate Theses and Dissertations

Florida has emerged in recent years as a breeding ground for a new generation of anti-LGBTQ+ legislation. The state has introduced 10 anti-LGBTQ+ laws so far in 2023, touching on issues such as bathroom access, healthcare, and education. This paper analyzes the experiences of queer and transgender people living in Florida to ask: How do LGBTQ+ people in Florida cope phenomenologically with rising anti-LGBTQ+ discrimination? Drawing on data from 22 interviews with LGBTQ+ people situated in and around Florida in 2023, this paper captures a distinct political moment for the people that I spoke with, as anti-LGBTQ+ sentiments continue to …


Employing The Use Of Molecular Dynamics To Explore Protein Stability And Optimize Free Energy Protocols, Taylor A. Rodman Nov 2023

Employing The Use Of Molecular Dynamics To Explore Protein Stability And Optimize Free Energy Protocols, Taylor A. Rodman

USF Tampa Graduate Theses and Dissertations

Molecular dynamics (MD) is a powerful technique that can be used to provide informationabout a system over time. MD simulations can be used to explore behaviors of many systems such as protein-ligand interactions protein-protein interactions. Additionally, these simulations can be used to generate trajectories of a system to further be used for free energy simulations. The work discussed in Chapter 2 involves the use MD simulations to identify potential drug candidates capable of binding to and stabilizing the nuclear binding domain of the Cystic Fibrosis Transmembrane Conductance Regulator protein. Using ProBiS, we were able to find a potential binding site …