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Takeda Pharmaceutical Rare Hematology Strategic Audit, Brian Duval Nov 2022

Takeda Pharmaceutical Rare Hematology Strategic Audit, Brian Duval

Honors Program: Senior Projects (Public)

Takeda Pharmaceutical Company is a large Japanese-based multinational pharmaceutical company that manufactures treatments for many different diseases. It is the largest pharmaceutical company in Asia and has a significant share in markets across the world. This report focuses specifically on Takeda’s treatments for rare bleeding disorders under its Rare Diseases & Hematology division. Using internal and external analysis tools, this report seeks to understand how Takeda has created and sustained competitive advantages in the complex environment of the pharmaceutical industry. Specific tools used to highlight this include Porter’s Five Forces and PESTEL analyses. This report also examines the environment surrounding …


Who Fears Strangers And Spiders: Political Ideology And Feeling Threatened, Thomas Lukaszewicz Oct 2022

Who Fears Strangers And Spiders: Political Ideology And Feeling Threatened, Thomas Lukaszewicz

Honors Program: Senior Projects (Public)

In this study, I evaluated the correlations between threat sensitivities and political ideology. Two hypotheses were tested. First, I hypothesized that conservatives would have higher social threat sensitivity than liberals, with social threat defined as a threat dependent on outgroup or social actions (Barclay & Benard, 2020). Second, I hypothesized that conservatives would have higher disgust sensitivity than liberals. To test these and related hypotheses I used a 2018 Qualtrics national demographically representative sample that included 1031 participants. To operationalize threat sensitivity, I used items asking participants to rate how threatened they felt by various fears. These individual items were …


Safety In Policy: An Assessment Of The Utilization And Perceived Efficacy Of Sex Offender Legislation, Morgan Graham Oct 2022

Safety In Policy: An Assessment Of The Utilization And Perceived Efficacy Of Sex Offender Legislation, Morgan Graham

Honors Program: Senior Projects (Public)

Current sex offender legislation in the United States is the result of a number of laws passed during the 1980-1990s. This study evaluates the efficacy and perception of these laws in Nebraska, including registration, community notification, and housing restriction policies. Using data from the Nebraska Annual Social Indicators Survey (NASIS), 1,814 people from 2008 and 1,232 people from 2017 were examined to determine the efficacy and popularity of sex offender legislation and how the data has changed over time. Results showed that only a minority of Nebraskans have accessed the registry. Of those who checked, women and individuals with children …


The Impact Of The Inclusion Of Grains In A Canine Diet On The Animal's Overall Health, Rachel Bruner Oct 2022

The Impact Of The Inclusion Of Grains In A Canine Diet On The Animal's Overall Health, Rachel Bruner

Honors Program: Senior Projects (Public)

The objective of this senior project was to examine the impacts that grains in a canine diet have on the overall health of the animal. Specifically, there was a focus on the nutritional attributes of grains, potential concerns regarding their inclusion in foods, misconceptions from consumers about grains in pet food, and alternatives to grains used in some diet formulations. The method of research for this project was a literature review. Scholarly articles focused on the various subtopics which helped to answer the research question were reviewed and included throughout the following discussion. Ultimately, the review of various literature resulted …


A Strategic Audit Of Hasbro, William Weiner, Amanda Fuechtmann, Avery Smith, Michaela Webb, Zach Buhman Oct 2022

A Strategic Audit Of Hasbro, William Weiner, Amanda Fuechtmann, Avery Smith, Michaela Webb, Zach Buhman

Honors Program: Senior Projects (Public)

This strategic audit dives into ten components of Hasbro’s strategic management. The first component discusses Hasbro’s history and current strategic leadership. This is followed by an analysis of the impacts of its external and internal environment. Next, the audit examines Hasbro’s recent performance and competition it faces in the Toy Wholesaling industry. The sixth, seventh, and eighth components consider different levels of strategy that Hasbro pursues. Lastly, the strategic audit considers Hasbro’s corporate governance and its organizational structure and controls.

Overall, we conclude that Hasbro is a mature company in a slow-growing industry. Its ability to translate its iconic and …


Executive Functioning In Language Learning Disabilities: Defining Executive Functioning, Executive Functioning Deficits, And Clinical Intervention Strategies To Support Children, Kaylie Trumble Oct 2022

Executive Functioning In Language Learning Disabilities: Defining Executive Functioning, Executive Functioning Deficits, And Clinical Intervention Strategies To Support Children, Kaylie Trumble

Honors Program: Senior Projects (Public)

This thesis aims to select a working definition of executive functioning (EF) to identify possible EF deficits and clinical interventions strategies to support children. Included are EF deficits, ways of assessing EF components, and intervention strategies for executive dysfunction in LLD. Scenarios are provided to demonstrate both matching strategies to a child and strength/deficit in EF, along with a sample intervention script.


Stress Arising From The Covid-19 Pandemic: Impacts On Coparenting Quality And Child Internalizing And Externalizing Problems, Michelle R. Ebrahim Oct 2022

Stress Arising From The Covid-19 Pandemic: Impacts On Coparenting Quality And Child Internalizing And Externalizing Problems, Michelle R. Ebrahim

Honors Program: Senior Projects (Public)

Since emerging in late 2019, the highly contagious coronavirus disease (COVID-19) has caused worldwide disruptions, with major shutdowns in school, work, and other aspects of life. These stressors uniquely impacted families with young children. The present study investigated the impact of the pandemic on family functioning and risk for child internalizing and externalizing problems during the first year after the pandemic. The study included three waves of data collection from a larger longitudinal study aimed at understanding how couples navigate the prenatal-postpartum transition and the impacts of the family on early child development. We found that family pandemic-related stress was …


Intestinal Parasite Prevalence In Fecal Samples In Nebraska Dog Parks, Kristianna Muller Oct 2022

Intestinal Parasite Prevalence In Fecal Samples In Nebraska Dog Parks, Kristianna Muller

Honors Program: Senior Projects (Public)

From February to April 2022, fecal samples were collected from eight dog parks in the Omaha and Lincoln, NE areas. A total of 160 samples were collected and assessed for the presence of intestinal parasites. The zinc sulfate double centrifugal flotation technique was used to determine infection. Out of the 160 samples, ten were positive for parasite contamination (6.25% prevalence). The most observed parasites were hookworms, found in 3.75% of all samples (6/160). Cystoisospora, Giardia, Toxocara canis, and Toxascaris leonina were all found only once, for a prevalence of 0.625% each. Compared to other studies, our infection …


Real Time Call-Flagging System To Respond To Suicidal Ideation In Call Centers, Vishnu Menon, Joseph Carrigan, Charles Floeder, Thomas Walton, Devin Mcguire May 2022

Real Time Call-Flagging System To Respond To Suicidal Ideation In Call Centers, Vishnu Menon, Joseph Carrigan, Charles Floeder, Thomas Walton, Devin Mcguire

Honors Program: Senior Projects (Public)

The 2021-2022 Signature Performance Design Studio team developed a live audio call-flagging system that enables faster responses and new response pathways to veteran crises by call service representatives and their management team. Using a custom made deep learning model, live audio streaming server, and Teams broadcasting add-on, the system empowers Signature Performance call service representatives to make quicker and more well informed decisions to provide veteran’s the best care possible.


Analysis Of The Effectiveness Of Different Techniques For Creating Cross-Platform Compatible Software, Michael Westberg May 2022

Analysis Of The Effectiveness Of Different Techniques For Creating Cross-Platform Compatible Software, Michael Westberg

Honors Program: Senior Projects (Public)

Creating cross-platform compatible software is a major issue in a world where users utilize a variety of devices and platforms. To ensure that a piece of software is accessible to as many users as possible, software must be cross-platform compatible. There are four main approaches that can be done to achieve this state of being cross-platform compatible, each with both advantages and disadvantages. These methods are: creating the software as separate binaries, using a scripting language with a cross-platform interpreter, compiling to an intermediate language, and creating the software as a web application. This paper will discuss how each of …


Evaluation Of Selected Computer Software For Concussion Recovery And Diagnosis, J.P. Jensen May 2022

Evaluation Of Selected Computer Software For Concussion Recovery And Diagnosis, J.P. Jensen

Honors Program: Senior Projects (Public)

Acquired traumatic brain injuries, such as concussions, impact many athletes participating in sports, particularly at the high school, collegiate, and professional levels. The risks posed by concussions – particularly when an athlete suffers repeated injuries – demands that protocols and tools be developed to maximize athlete health and safety. Computer technology can perform critical roles in the analysis and management of concussions. While specialized devices in the areas of imaging and impact sensing, are most associated with concussion management, researchers within the last two decades have increasingly explored the incorporation of various consumer technologies into the identification and treatment of …


A Strategic Audit Of Seaworld, Jaden Capaldi, Rachel Jendro, Jacob Mir, Sophie Newman, Tommy Wolfe May 2022

A Strategic Audit Of Seaworld, Jaden Capaldi, Rachel Jendro, Jacob Mir, Sophie Newman, Tommy Wolfe

Honors Program: Senior Projects (Public)

No abstract provided.


Nelnet: Potential Entrance Into An Emerging Market Nelnet: Potential Entrance Into An Emerging Market, Gage Randall, Landon Kennedy, Marcus Kennedy, Alex Botkin, Ben Samway May 2022

Nelnet: Potential Entrance Into An Emerging Market Nelnet: Potential Entrance Into An Emerging Market, Gage Randall, Landon Kennedy, Marcus Kennedy, Alex Botkin, Ben Samway

Honors Program: Senior Projects (Public)

Nelnet, Inc. (Nelnet) approached the Nebraska Business Honors Academy seeking assistance researching a potential new business venture. Our group explored opportunities in the market Nelnet is considering entering, examined various types of innovation, and engaged in the creative design thinking process. To form the basis of our recommendation, we met with professionals in the related industry, Nelnet employees, and faculty at the University of Nebraska-Lincoln. Our final task involved recording a presentation on our recommendation to Nelnet concerning this new business opportunity, accompanied by a final report summarizing our proposal. Through this project, we learned how to develop innovative ideas …


The Impact Of China's Environmental And Trade Policies On U.S. Plastic And Paper Waste Exports, Savant Nzayiramya, John C. Beghin Apr 2022

The Impact Of China's Environmental And Trade Policies On U.S. Plastic And Paper Waste Exports, Savant Nzayiramya, John C. Beghin

Honors Program: Senior Projects (Public)

This article documents major environmental and trade policy changes in China and their impact on plastic and paper waste trade between the U.S. and China and other trade partners. The article explains how U.S. plastic waste exports have been nearly annihilated by these policies. Paper waste trade is more resilient and has survived the policy shifts in China, although quite diminished.


Redfin Strategic Analysis, Steffanie Hitz Apr 2022

Redfin Strategic Analysis, Steffanie Hitz

Honors Program: Senior Projects (Public)

No abstract provided.


The Wheels On The Bus Go Round And Round: Rethinking The St. Louis Busing Program, Tango Walker, Ketosha Harris Apr 2022

The Wheels On The Bus Go Round And Round: Rethinking The St. Louis Busing Program, Tango Walker, Ketosha Harris

Dissertations

This autoethnography shares our personal experiences and counter-narratives in the St. Louis busing program. Through our mission we expound on experiences and real-life situations as seen through our lens as a student and a mother in the St. Louis busing program. Critical race theory (CRT) was used as an essential framework allowing us to focus on the following four tenets: counter-stories, permanence of racism, whiteness as property, interest convergence. (Anderson, et al., 2017). Critical race theory (CRT) is the framework in social sciences that examines society and culture as it relates to categorization of race, law and power (Lynn & …


Developing Indie Games With Agile, Camden Obertop Apr 2022

Developing Indie Games With Agile, Camden Obertop

Honors Program: Senior Projects (Public)

Agile software development has ushered in major improvements to the development of software in the 21st century. Video game development is a form of development that is unique from other types of software engineering, as it can involve work from artists, musicians, voice actors, and others. This paper explores the question whether agile software development as Scrum is an effective tool for creating video games. Ultimately, it can be seen that agile is a very important asset to game developers.


Understanding Boundary Turbulence And Privacy Rules From The Receiver’S Perspective In Mental Illness Disclosures, Ian Maltas Apr 2022

Understanding Boundary Turbulence And Privacy Rules From The Receiver’S Perspective In Mental Illness Disclosures, Ian Maltas

Honors Program: Senior Projects (Public)

The present study aims to address a gap in current research focusing on relational outcomes of mental illness disclosures by studying the perspective of people who listen to the disclosures (called “receivers”). This study uses Communication Privacy Management Theory to analyze the process of disclosure, and its main research focus is on motivations for disseminating private information, and how that impacts relationships and privacy rules between co-owners of information. A thematic analysis was conducted to answer this inquiry, and a data conference was held to determine relevant themes in the data. The present study finds that people chose to tell …


Sex Differences In Lateral Hypothalamic Extracellular Glucose Concentrations During Cumulative Dosing Of Methamphetamine In Rats, Joshua A. Jolton Apr 2022

Sex Differences In Lateral Hypothalamic Extracellular Glucose Concentrations During Cumulative Dosing Of Methamphetamine In Rats, Joshua A. Jolton

Honors Program: Senior Projects (Public)

The present study experimentally investigated sex differences in lateral hypothalamic glucose concentrations following cumulative dosing of methamphetamine. Male (n=17) and female (n=11) rats were surgically implanted with enzyme-based glucose biosensors in the lateral hypothalamus. Rats then received a saline injection followed by four methamphetamine doses (0.025 mg/kg, 0.05 mg/kg, 0.1 mg/kg, and 0.2 mg/kg) spaced 55 minutes apart. We found that while there was a general decrease in glucose baseline throughout the study for both sexes, the magnitude of the decrease was significantly greater in females compared to males. On a rapid timescale, fixed sex effects existed at the lower …


Relationship Between Gender And Symptom Severity For Youth Who Have Been Sexually Abused, Zoe Erickson Apr 2022

Relationship Between Gender And Symptom Severity For Youth Who Have Been Sexually Abused, Zoe Erickson

Honors Program: Senior Projects (Public)

Childhood sexual abuse is a recurring problem which negatively affects thousands of children and adolescents every year. This is a traumatic event which can cause distress for individuals post sexual abuse well into adulthood. Because of this, it is important for practitioners to understand what symptoms could be present post abuse, as well as factors that may impact the presence and severity of these symptoms. Using data from the Project SAFE group treatment program including 126 adolescents aged 12-19, this study aims to further examine how factors such as gender of the individual will affect their symptoms post sexual abuse. …


Remotely Close: An Investigation Of The Student Experience In First-Year Mathematics Courses During The Covid-19 Pandemic, Sawyer Smith Apr 2022

Remotely Close: An Investigation Of The Student Experience In First-Year Mathematics Courses During The Covid-19 Pandemic, Sawyer Smith

Honors Program: Senior Projects (Public)

The realm of education was shaken by the onset of the COVID-19 pandemic in 2020. It had drastic effects on the way that courses were delivered to students, and the way that students were getting their education at the collegiate level. At the University of Nebraska – Lincoln, the pandemic dramatically changed the way that first-year mathematics courses looked for students. By Spring 2021, students had the opportunity to take their first-year math courses either in-person or virtually. This project sought to identify differences between the two methods of course delivery during the Spring 2021 semester, regarding interaction with peers …


Biomechanical Analysis Of Athletes Sprinting With Varying Degrees Of Resistance, Michaela Ott Apr 2022

Biomechanical Analysis Of Athletes Sprinting With Varying Degrees Of Resistance, Michaela Ott

Honors Program: Senior Projects (Public)

Utilizing resistance methods for sprinters is a common approach to their training. In this study, six athletes from the University of Nebraska-Lincoln Women’s Track and Field Team ran a series of sprints using a resistance machine to collect data regarding the change in power output, stride length, level of trunk tilt with respect to the ground, and acceleration throughout a distance of ten meters when different amounts of resistant forces were applied to the athlete. It was hypothesized that as resistance increased, power output would increase, stride length would decrease, the runners would become more horizontal resulting in a larger …


The Public’S Preferences In Supreme Court Rationale, William Svob Mar 2022

The Public’S Preferences In Supreme Court Rationale, William Svob

Honors Program: Senior Projects (Public)

Public approval of the Supreme Court has been decreasing in recent years. Given the literature’s consensus that Supreme Court rulings coincide with popular opinion more often than not, the decrease in popularity cannot be explained away by assuming the justices have made a series of widely despised rulings. This raises questions about what exactly the public wants the Supreme Court to do. There is an abundance of research covering the many factors that influence a justice to rule in a particular manner, but there is little written about what the average American believes should influence the Court. This study is …


Source Of Off-Type Frequencies In Winter Wheat Varieties, Michaela Benes Mar 2022

Source Of Off-Type Frequencies In Winter Wheat Varieties, Michaela Benes

Honors Program: Senior Projects (Public)

The enzyme polyphenol oxidase (PPO) is undesirable in most wheat products due to the discoloration it causes. Purifying wheat varieties through selective breeding is the best way at getting rid of PPO in a variety. The variety NW15443 was planted in both a field in McCook, NE, and in a greenhouse in Lincoln, NE. Individual heads were snapped from the field and the greenhouse seed was harvested in bulk. After completing a PPO test of the seed, it was determined that the percentages of off-type frequencies from the field seed and the greenhouse seed were 11% and 3.6%, respectively. Using …


The Effect Of Store-To-Store Energy Transfers On The Global Dynamics Of Aircraft, Guilherme Mainieri Eymael Mar 2022

The Effect Of Store-To-Store Energy Transfers On The Global Dynamics Of Aircraft, Guilherme Mainieri Eymael

Honors Program: Senior Projects (Public)

This study analyzes the energy transfer mechanisms when nonlinear devices (stores) are attached to a linear model airplane. For that, a reduced-order model (ROM) was derived to simulate the first two flexible modes of vibration of the primary structure (aircraft) with one store in each wing. Each store can either be locked or unlocked. When locked, it only contributes as mass-effect, and when unlocked, it adds nonlinearity to the system. Simulations were then performed with either both stores locked, one store unlocked, or both stores unlocked. It was found that the attachment of nonlinear stores in the ROM changes the …


An Evaluation Of Tractors Tested At The Nebraska Tractor Test Lab And The Effect Of Epa Emission Standards Based Upon Average Pto Horsepower And Fuel Efficiency, Dalton Erickson Mar 2022

An Evaluation Of Tractors Tested At The Nebraska Tractor Test Lab And The Effect Of Epa Emission Standards Based Upon Average Pto Horsepower And Fuel Efficiency, Dalton Erickson

Honors Program: Senior Projects (Public)

Newly released tractor models are tested to ensure they meet advertising claims. This thesis utilizes tractor test data to analyze performance trends in tractors based upon their power take off (PTO) horsepower and fuel efficiency and it evaluates how the average fuel efficiency of tractors was affected by the introduction of emission standards by the United States Environmental Protection Agencies. In conclusion, tractors have shown continuous improvement and growth in both fuel efficiency and PTO horsepower, and emission standards have had a small, positive effect on tractors’ average fuel efficiency.


Tiny Earth, Tinier Microbes: An Experiential Learning Approach To Antibiotic Discovery, Emily Kassing Mar 2022

Tiny Earth, Tinier Microbes: An Experiential Learning Approach To Antibiotic Discovery, Emily Kassing

Honors Program: Senior Projects (Public)

Antimicrobial resistance is one of the greatest global health challenges of the 21st century as antibiotic discovery has slowed even as scientific knowledge about AMR has progressed. At the same time, science education has turned to active learning approaches like CUREs, or course-based undergraduate research experiences, to achieve educational objectives while engaging students in real-life research. The Tiny Earth Project is a global research initiative that seeks to crowdsource antibiotic discovery by recruiting undergraduate students to screen soil samples for antibiotic producers. The goal of this study was to determine the viability of translating the Tiny Earth programming to …


Livestock Performance In Response To High Intensity Rotational Grazing System, Austin Kennedy Mar 2022

Livestock Performance In Response To High Intensity Rotational Grazing System, Austin Kennedy

Honors Program: Senior Projects (Public)

The production of livestock is composed of a variety of factors all effecting the outcome. For grazing livestock, a key factor in production is the grazing management system. Two of the most common grazing management systems are continuous grazing and rotational grazing. There has been evidence found proving benefits of rotational grazing in regard to vegetation productivity, and prevention and restoration of degraded rangeland. However, there is a lack of clear evidence on the relationship between grazing system and production metrics of livestock. Understanding this relationship can provide the necessary information for livestock producers in order to increase their production …


The Broadband Mapping Challenge: An Overview Of Rural Broadband Status And Policy Solutions For Nebraska, Payton Flower Mar 2022

The Broadband Mapping Challenge: An Overview Of Rural Broadband Status And Policy Solutions For Nebraska, Payton Flower

Honors Program: Senior Projects (Public)

Broadband, the availability of high-speed internet service for the transmission of electronic data, it is a critical component in the daily life of Americans. However, there is significant disparity in the United States between urban and rural areas in regard to broadband availability and adoption. This issue has created what is known as the “digital divide”, a situation in which lower income, rural residents, and those living on tribal lands are most severely impacted by limited broadband services. “Broadband Mapping” refers to a data collection process that is primarily overseen by the Federal Communications Commission. Unfortunately, a variety of flaws …


A Documentation Of A Year As An Artistic Director For Unl, Philip Crawford Mar 2022

A Documentation Of A Year As An Artistic Director For Unl, Philip Crawford

Honors Program: Senior Projects (Public)

The goal of this project was to document a year of being an Artistic Director for UNL’s student run theatre company Theatrix. Through this documentation, I will be able to reflect upon and learn from my experiences as a leader, director, and theatre maker.

This thesis will be broken up into eight different parts to outline the eight different stages I experienced as Artistic Director this year: season selection, the 24-hour Play Festival, The Revolutionists, The Thanksgiving Play, Clown Bar, season changes, Based on a Totally True Story, and Lemons, Lemons, Lemons, Lemons, Lemons. Through these eight stages, I will …