Community College Leadership Commons^™

Design And Optimization Of A Mycoplasma Detection Assay, Carlos J. León-Rodríguez, Richard J. Noel, Jr., Phd, Tirtsa Porrata-Doria, Ms

Journal of Health Disparities Research and Practice

Mycoplasma are among the smallest free living microorganisms. These bacteria grow slowly, lack a rigid cell wall and are not eliminated by filter sterilization methods used in tissue culture. Mycoplasma infection affects biochemical and genetic aspects of cultured cells, resulting in experimental inconsistency. Therefore, it is necessary to establish routine testing for mycoplasma contamination in tissue culture laboratories.

Our goal is to develop a reliable and cost-effective test for mycoplasma in cell culture based on established methods found in literature. We first cloned and sequenced a PCR product from a commercial mycoplasma detection kit. Sequencing revealed the 16s rRNA as …

Role Of Hiv-1 Nef Lysine Residues 4 And 7 In The Interaction With Calnexin And Inhibition Of Abca1 Activity, Valeria Kaufman, Michael Burkinsky, Md, Phd, Ruth Hunegnaw, Msc, Phd Candidate

Journal of Health Disparities Research and Practice

Patients infected with HIV are at increased risk of developing atherosclerosis, a result due partly to the functional impairment of cellular cholesterol transporter, ATP-binding cassette transporter A1 (ABCA1). This transporter mediates efflux of cholesterol from cells to high density lipoprotein, thus allowing cells to maintain normal levels of cholesterol. When ABCA1 function is inhibited, cells, and in particular macrophages, accumulate cholesterol, resulting in formation of atherosclerotic plaques. The HIV-1 protein, Nef downregulates ABCA1 and inhibits the activity of this protein, thereby reducing cholesterol efflux and promoting atherosclerosis, but the molecular mechanism by which Nef inhibits ABCA1 is unknown.

Previous studies …

Collagen Iv Assembly: Production Of A Recombinant Construct For Mechanistic Studies, Kennedy Harris, Billy Hudson, Phd, Isi Ero-Tolliver, Phd, Kyle Brown, Phd

Journal of Health Disparities Research and Practice

Basement membranes, specialized extracellular matrix, provide mechanical support for epithelial cells and shape cell behavior by interacting with cell receptors. Collagen IV, the predominant component of basement membrane, comprises six genetically distinct alpha chains (α1 to α6) that assemble to form protomers, which associate to form hexamers, in the scaffold. Non-assembly due to mutations within alpha chains give rise to kidney diseases. Yet, the mechanism of assembly is poorly understood.

Preliminary data in our lab indicated that amino acid 78 of collagen IV α2 NC1 (non-collagenous) domains may play a role in a chloride-dependent switch that supports hexamer formation. We …

Sex Differences In The Sex Differences In The Effects Of Environmental Enrichment After An Early Life Stressor, Alfredo Gutierrez, Annelyn Torres-Reverón, Phd, Raura Doreste-Méndez

Journal of Health Disparities Research and Practice

Studies have shown that environmental enrichment can compensate for the effects of an early life stressor such as maternal separation. Behavioral responses and immunohistochemical markers in rats are affected by environmental enrichment after maternal separation. In this study we seek to investigate whether sex influences the behavioral responses of environmental enrichment after maternal separation.

Prior scientific evidence suggests that there are behavioral sex differences in: 1) neural processes underlying successful or failed fear extinction (Gruene et al, 2014); (2) prenatal stress exposure and response to behavioral anxiety tests (Said et al, 2015); and (3) glutamate receptor expression in response to …

Cox2 Plays An Important Role In Maintenance Of Mammary Cancer Stem Cell Population In Human Breast Cancer Cell Lines, Mayra Garcia, Shehla Pervin, Phd, Easter Thames, Meher Parveen, Phd, Melanie Baker

Journal of Health Disparities Research and Practice

Breast cancer is a malignant growth in the adipose-rich mammary gland. Initiation and progression of breast tumors involve multiple cell types, among which mammary cancer stem cells play an important role. There are two main types of adipocytes; white adipocytes have previously been found to influence the disease while brown adipocytes, which uniquely express uncoupling protein 1 (UCP1), were recently detected in breast tumors.

We have detected Myf5, a transcription factor, which is expressed in the progenitor population of brown adipocytes, in breast cancer cell lines. We also found an association between expression of Myf5 and COX2 (or Ptgs2), which …

The Role Of Integrin-Associated Protein “Pinch” In Kidney Development, Tyrone Gamble Jr, Roy Zent, Phd, Bertha C. Elias, Phd

Journal of Health Disparities Research and Practice

PINCH (a particularly interesting new cysteine-histidine-rich protein) is a protein that binds with Integrin-linked kinase and Parvin, to form an IPP complex. This complex is formed only when integrin molecules are activated upon interaction with the basement membrane. The IPP complex then acts as a platform for other proteins to come together and regulate cell signaling to and from the extracellular matrix (ECM). This allows for various cellular activities to progress like cell adhesion, migration, proliferation, etc. There are two types of PINCH proteins, PINCH-1 and PINCH-2. Studies from our group have shown that the lack of PINCH-1 in the …

Nitric Oxide And Cyclic Gmp Signaling In Cancer Therapy, Armond Dorsey, Ferid Murad, Md, Phd, Ka Bian, Md, Phd

Journal of Health Disparities Research and Practice

The nitric oxide-3’,5’-cyclic guanosine monophosphate signaling pathway (NO-cGMP signaling pathway) is a well-known signal transduction pathway which elicits several physiological processes including: cell proliferation, vasodilation, cardiac protection, etc. In this pathway, NO binds to the ferrous heme of histidine-105 on the prosthetic heme of the β₁ subunit of soluble guanylyl cyclase, resulting in the production of cGMP. This pathway, however, is inhibited in certain cancer cells—as observed in glioma cell lines. As a result, the production of cGMP is reduced. This mechanism may facilitate uncontrolled tumor cell growth.

The cancers under research—lung carcinoma, glioma, and pancreatic carcinoma—are all highly …

Potential Cost Savings Of Not Doing Cd4 Counts In Hiv Positive People In Rhode Island With An Undetectable Viral Load, Ruth Dele-Oni, Ferdinand Schumacher, Zachary Markus, Timothy Flanigan, Md

Journal of Health Disparities Research and Practice

CD4 cells fight infections in the body. When someone contacts Human Immunodeficiency Virus (HIV), their CD4 cells are taken over by HIV which turns them into manufacturers of many copies of the virus. The Viral Load (VL) measures the amount of virus in the blood. When HIV takes over the CD4 cells, the VL increases while the number of necessary CD4 cells decreases. When patients maintain stable treatment, their CD4 counts rise, and VLs may become undetectable, indicating the virus is too little to be detected in their blood. Knowing this, is frequent CD4 counts necessary for those with undetectable …

Defining The Role For Zbp-89 In Atm-Mediated Dna Damage Response To Irradiation In The Intestine, Christine Carethers, Juanita L. Merchant, Md, Phd

Journal of Health Disparities Research and Practice

ZBP-89 (ZNF148, Zfp148) is a zinc-finger transcription factor that inhibits cellular proliferation when overexpressed in cell lines. ZBP-89 forms a protein-protein interaction with p53 and Ataxia-telangiectasia mutated (ATM). However, it is unclear how the interaction modulates the function of these two proteins in vivo.

Double strand DNA breakage induced by -irradiation induces ATM phosphoinositol kinase activity, which initiates a cascade of events culminating in cell cycle arrest, DNA repair or apoptosis. Elevated levels of ZBP-89 induce growth arrest and apoptosis in gastrointestinal cell lines. Therefore, we hypothesize that ZBP-89 facilitates cell growth arrest and activation of the DNA repair pathway …

Induction Of Dusp9 In Xenografts From Human Breast Cancer Cell Lines Increases Mammary Cancer Stem Cells, Albert Barrios, Meher Parveen, Phd, Easter Thames, Melanie Baker, Shelha Pervin, Phd

Journal of Health Disparities Research and Practice

Breast cancer remains a complex disease that kills 40,000 women every year. Initiation and progression of breast cancer is influenced by heterogeneous groups of cells, including mammary cancer stem cells (MCSCs). Progression of this dreadful disease is driven by many signaling pathways among which MAPK pathway is highly prominent. Since targeting prominent kinases in MAPK pathway has been unsuccessful to control breast cancer, it is important to examine the phosphatases that regulate the activity of these kinases.

Using xenograft model from breast cancer cell lines, our lab has found that during the initial stages of xenograft development (week 1-4, 100-200mg …

Preparing Underrepresented High School Students To Increase Diversity In The Research And Health Professions, Dolores E. Caffey-Fleming, Ms, Mph, Christopher Reid, Md, Phd

Journal of Health Disparities Research and Practice

This article introduces the work that was done through the Coordinating Center at Charles R. Drew University of Medicine and Science.

The Step Up Program, Lawrence Agodoa, Md

Journal of Health Disparities Research and Practice

The Short-Term Research Experience Program for Underrepresented Persons (STEP-UP) was established as part of the NIDDK Strategic Plan on Minority Health Disparities. This article provides an overview and introduction of this program. All of the articles that are included in this special issue reflect the work of our coordinating centers, the mentors and their staff, as well as the students.

Implementation Of State Developmental Education Policy: A Multiple Case Study Of Community College Faculty Perceptions Of Involvement, Shirley Davenport

Department of Educational Administration: Dissertations, Theses, and Student Research

Numerous studies have indicated that developmental education as it is currently offered in many colleges and universities produces dismal results, with student success rates averaging as low as 25%. To address this issue, legislators in some states have begun to intervene, adopting policies that vary from suggestions for improvements to mandated pedagogical approaches. However, given the higher education organizational environment, the manner in which any change is implemented can be key to its success.

The purpose of this comparative multiple case study was to describe and interpret the perceptions of developmental education faculty regarding their level of involvement in developmental …

Cultural Influences Of Resource Dependence: Community College Administrator Perceptions Of Implementing Initiatives Related To Tennessee’S Performance Funding Model, John Owen Driskill

Electronic Theses and Dissertations

The purpose of this phenomenological research study was to describe the cultural influences of resource dependence for community college administrators responsible for the implementation of initiatives related to Tennessee’s new performance funding program. Tennessee’s funding formula, considered one of the most aggressive and robust in the country, is among a second generation of performance funding programs commonly referred to as performance funding 2.0. Cultural influences of resource dependence were defined as values, beliefs, and customs that influence administrator efforts to improve institutional outcomes and acquire additional resources through performance funding.

A top performing community college in terms of the performance …

Two-Year College Faculty Perspectives On Developmental Student Persistence: A Case Study, Mary Colleen Patterson

All Theses And Dissertations

This study sought to understand the perspectives of two-year college composition faculty concerning the persistence of students in their developmental composition courses. Research has shown that developmental students are a population at risk for leaving college before completing their degree programs and that students are more likely to persist to reach their goals when they’ve built meaningful connections with faculty. Many factors affect faculty ability to connect with developmental students such as faculty history, teaching preparation, and work load.

This study answered four research questions: 1) how do faculty describe and perceive their experience in encouraging developmental students to persist? …

Establishing Community In Online Courses: A Literature Review, Amy J. Pilcher

College Student Affairs Leadership

The purpose of this literature review is to examine the evolution of online learning over the last several decades in relation to student engagement. Much has been made of both the successes and failures of online learning and, consequently, much has been written to enumerate the reasons for those successes and failures. After lengthy review, a great deal of the writing indicates that the relative success or failure of a student is caused by a confluence of three factors: the student, the environment, and the faculty. Online learning is unique in that a much greater share of the burden of …

Delivering Disability Accommodations At A Community College: A Case Study, Caolfionn B. Yenney, Janie Sacco Ii

College Student Affairs Leadership

This case study explores the Office of Disability Support Services (DSS) at Northern Midwestern Community College (NMCC). Like many state institutions of higher education, NMCC has undergone continued budgetary cuts, some of which have impacted their services. Additionally, NMCC faces limited support from administration and resistance from instructors to provide accommodations. Taking the position of the accommodations coordinator, this case study challenges readers to consider a student concern from an institutional, collaborative, student response, and strategic perspective.

Black Lives Matter, But Not Here: A Case Study, Jason R. Goode, Z Nicolazzo

College Student Affairs Leadership

Recently, the United States has experienced a wave of social movements that include protests and digital social justice movements through Facebook and Twitter. These movements have been sparked as a response to systematic racism within the university landscape and the police force. This case study looks into systematic racism at a large public university college campus. The setting is in a college town on a city street that connects the city jail to the campus. Readers will be introduced to several characters that are important to the story before reading an account of the tug of war treatment of Black …

Editor’S Corner: Strengthening Perspective By Exploring Complex Cases, Outcomes, And Literature, Lauren Presutti

College Student Affairs Leadership

Note from the editor-in-chief.

The Remedy That's Killing: Cuny, Laguardia, And The Fight For Better Math Policy, Rachel A. Oppenheimer

Dissertations, Theses, and Capstone Projects

Nationwide, there is a crisis in math learning and math achievement at all levels of education. Upwards of 80% of students who enter the City University of New York’s community colleges from New York City’s Department of Education high schools fail to meet college level math proficiencies and as a result, are funneled into the system’s remedial math system. Once placed into pre-college remedial arithmetic, pre-algebra, and elementary algebra courses, students fail at alarming rates and research indicates that students’ failure in remedial math has negative ripple effects on their persistence and degree completion. CUNY is not alone in facing …

Socio-Economic Inequalities, Academic Failure, And Institutional Interventions: What Cuny Is Doing To Help Its High Risk Populations, Cynthia Constant

Dissertations, Theses, and Capstone Projects

There is a lack of adequate research of the City University of New York’s (CUNY) school-based programs and services that are designed to aid and empower students in achieving academic success. These programs serve an urban based student population. A substantial number of these students are of low income and from historically underrepresented cultural and ethnic backgrounds. A significant portion of these students also attend a community college like Kingsborough Community College (KBCC) in the CUNY system. For most of this student population academic success is not easily obtained. This study examines the rationale behind student failure, as well as, …

Beyond Behavior, Craig C. Laupheimer

Scholarship and Engagement in Education

Teaching to engage students with Attention Deficit Hyperactivity Disorder (ADHD) can inspire the whole classroom and make teaching and learning engaging and exciting. Although teachers and students alike face a challenging educational landscape, much can be done to empower students with special needs. Teaching with the whole classroom in mind with an emphasis on hands on, explorative and inspirational learning experiences to accommodate for these students strengthens and causes student engagement and agency. This article highlights the challenges and potential breakthroughs possible for classroom instruction specifically where the ADHD student is concerned and looks towards teaching mindfulness and empowerment as …

Breaking The Cycle: Exploring The Impact Of Low Literacy And Systemic Barriers On Socioeconomic Mobility In Houston, Texas, Stephanie M. Ross

Electronic Theses and Dissertations

This phenomenological qualitative study addressed the impact of low literacy and systemic barriers on socioeconomic mobility among adult learners in Houston, Texas. Persistent low literacy rates in the region have perpetuated educational and economic disparities, restricting access to stable employment, income growth, and advancement opportunities. The study aimed to examine how adult education participants experience low literacy, how these experiences affect their socioeconomic outcomes, and how adult education program directors interpret and address these challenges. A qualitative research design was employed to capture in-depth perspectives from both adult learners and program directors. Data collection involved semistructured interviews and structured surveys. …

Online Cte In The Community College, Brian T. Dietz, Rachal Etshim

Research and Creative Activities Poster Day

Community colleges serve the most diverse student population with regard to age, race and ethnicity, and socioeconomic status. These characteristics mirror those of students who enroll in career and technical education (Bragg, 2001, 2014) and online courses (Aslanian & Clinefelter, 2013). Yet only a handful of studies have been conducted about online technical education in community colleges. Given the continued growth in online education (Allen & Seaman, 2015; Lokken & Mullins, 2015), increasing use of technology in the classroom, and the emphasis on career and technical education (CTE) as a means of increasing degree production, more information is needed about …

Tales From The Field: A Phenomenological Study On The Unique Challenges Iraq/Afghanistan Ptsd Veterans Experience While Attending A Community College In Southern California, Nick N. Arman

Dissertations

With the downsizing of U.S. military personnel and increased educational benefits offered by the Post-9/11 G.I. Bill, many Operation Iraqi Freedom (OIF) and Operation Enduring Freedom (OEF) veterans will enroll in a community college for education and training opportunities (Vacchi, 2012). A review of literature revealed the majority of OIF/OEF combat veterans in higher education suffered from symptoms consistent with posttraumatic stress disorder (PTSD; Ackerman, DiRamio, & Garza Mitchell, 2009; American Council on Education, 2009; Cate, 2014). The purpose of this phenomenological study was to understand the unique challenges experienced by OIF/OEF veterans diagnosed with PTSD when attending community college …

Dental Health Practices In Us College Students: The American College Health Association-National College Health Assessment Findings, Lori Dewald Edd, Atc, Mches, F-Aahe

Journal of Health Disparities Research and Practice

Objective: The purpose of this study is to investigate the dental health seeking practices of US college students. Participants: The total number of college students who participated in the ACHA-NCHA survey from 2000-2013 was 1,201,531. Methods: The data requested were the demographic questions and the dental health question from both the ACHA-NCHA I and II. The data were analyzed using SPSS version 20. Results: The percentage of students who reported having a dental exam and cleaning in the last year averaged 76.6% in this study period of time. However, dental health care declined annually following their freshman year. More females …

Information Literacy And Critical Thinking: The Power Of Success, Cheryl A. Clayton-Molina Dr.

National Youth Advocacy & Resilience Conference

Students and adults cannot just be excellent learners, but lifelong learners to keep pace in today’s world. Information literacy and critical thinking presentation provides skills for individuals to grow and develop as a person and professional. Individuals will learn:

Higher-Order Thinking

Problem solving

Effective and Positive Communication Skills

Setting Realistic Goals

Self-Development/Growth (Who are you)

Building Confidence

The Journey To The Top: Stories On The Intersection Of Race And Gender For African American Women In Academia And Business, Deanna R. Davis

Journal of Research Initiatives

This research study was designed to determine how the intersection of race and gender identities contributed to the elements of leadership development as perceived by eight African American female executives in academia and business. The researcher sought to explore strategies future leaders might utilize to address leadership development and career ascendency for African American females who aspire to leadership roles. A phenomenological research method was most appropriate for this research study to capture the lived experiences of individuals from their perspectives and to develop themes that challenged structural or normative assumptions.

This research study examined leadership development of eight African …

The Motivational Factors Of African American Men Enrolled At Selected Community Colleges, Ted N. Ingram, Lavon Williams, James Coaxum Iii, Adriel A. Hilton, Ivan Harrell

Journal of Research Initiatives

This manuscript is designed to call attention to the realities that are specific to African American male community college students. Using a qualitative research design, focus groups were conducted with 14 African American male students enrolled in an urban community college. This study uncovered that their educational experiences are consumed with personal challenges and academic obstacles. Students were asked to explain their motivation toward persistence at the urban community college. Participants within the study noted that motivational factors such as: (a) improving their life status, (b) societal pressure, (c) “man of the house,” and (d) faculty and staff encouragement, provided …

Realizing The Dream: African American Males’ Narratives That Encouraged The Pursuit Of Doctoral Education, Ted N. Ingram

Journal of Research Initiatives

This article used personal narratives to discover factors affecting the decision of African American males to consider doctoral education. This study was based on qualitative interviews with 18 African American male doctoral students enrolled at predominantly white institutions as they reflected on their reasons for pursuing an advanced degree. The following were found to influence their decision: (a) need for faculty encouragement, (b) motivation to pursue a doctorate, and (c) their personal motivations. Recommendations are offered for increasing the numbers of African American male doctoral students.