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Articles 39271 - 39300 of 1738259
Full-Text Articles in Entire DC Network
Finding Meaning In A Historical Fiction Of Cold War: A Case Study Of Pamuntjak’S Question Of Red, Margihon Bayu Putra Kaumpungan
Finding Meaning In A Historical Fiction Of Cold War: A Case Study Of Pamuntjak’S Question Of Red, Margihon Bayu Putra Kaumpungan
Bahasa dan Seni: Jurnal Bahasa, Sastra, Seni, dan Pengajarannya
The Cold War and its legacy in Southeast Asia, has been considered as one of the darkest parts of the region’s history including in Indonesia. Efforts to capture the painful memory of the Cold War had been established through various means including fictional storytelling. Among many literature discussing the dark history of the era, Laksmi Pamuntjak “Question on Red” had its distinctive presence since it was written in English. The utilization of English as a medium opens the door for English speaking readers to be able to dwell into a literature work that is considerably unfamiliar to their cultural context. …
Montana Kaimin, February 5, 2026, Students Of The University Of Montana, Missoula
Montana Kaimin, February 5, 2026, Students Of The University Of Montana, Missoula
Montana Kaimin, 1898-present
Student newspaper of the University of Montana, Missoula.
The World's Largest Saddle Dam At Risk: Multisensor Geohazard Analysis And Downstream Impacts, Hesham El-Askary, Hesham Morgan, Surendra Maharjan, Ali Elgendy, Wenzhao Li, Rejoice Thomas, Austin Madson, Cyril Rakovski
The World's Largest Saddle Dam At Risk: Multisensor Geohazard Analysis And Downstream Impacts, Hesham El-Askary, Hesham Morgan, Surendra Maharjan, Ali Elgendy, Wenzhao Li, Rejoice Thomas, Austin Madson, Cyril Rakovski
Mathematics, Physics, and Computer Science Faculty Articles and Research
The Grand Ethiopian Renaissance Dam (GERD) Saddle Dam, which holds approximately 89% of the main reservoir's live storage, is one of the largest and most critical auxiliary dams globally; its construction on Ethiopia's Blue Nile has consequently raised significant regional and international concerns regarding potential environmental impacts and geohazard risks. This study presents a comprehensive risk assessment of the GERD Saddle Dam by integrating high-resolution satellite data (GRACE, Sentinel-1, Sentinel-2, WorldView-3), hydrological modeling (SWAT), Persistent Scatterer Interferometry (PSI), geospatial analysis, and advanced statistical techniques. The results highlight critical structural vulnerabilities, including groundwater infiltration estimated at approximately 41 ± 6.2 billion …
Print, Pattern, Stick: Low–Cost Gecko–Inspired Adhesives Using Embedded Diffraction Structures, Motaz Hassan, Oluwafemi Fayomi, Ajay Mahajan, Joshua Faust
Print, Pattern, Stick: Low–Cost Gecko–Inspired Adhesives Using Embedded Diffraction Structures, Motaz Hassan, Oluwafemi Fayomi, Ajay Mahajan, Joshua Faust
University Research
Gecko-inspired adhesives offer strong, reversible, and directionally tunable adhesion, yet fabrication methods often depend on cleanroom lithography or proprietary molds, limiting scalability and accessibility. This study presents a low-cost, modular fabrication strategy combining high-resolution digital light processing 3D printing with 1000 lines/mm optical diffraction gratings to create hierarchical elastomeric adhesives. The resulting structures feature macroscale micropillars and embedded sub-micron surface topography, enabling effective contact splitting without advanced microfabrication. Mechanical testing reveals a nonlinear increase in shear performance with contact area, with maximum shear forces exceeding 80 N at 103.2 cm2. Peel testing across varied angles and surface areas demonstrates anisotropic …
The Setd2 L1609p Mutation Found In Leukemia Disrupts Methyltransferase Activity And Reduces Histone H3k36 Trimethylation, Christina Michail, Jérémy Berthelet, Ariel E Mechaly, Linh-Chi Bui, Haopeng Yang, Duo Cai, Amira Al Mahi, Aowei Xie, Valeria Bisio, Valentina Sirri, Jean-Marie Dupret, Fabien Guidez, Ximing Xu, Nicolas Joly, Leslie Regad, Mireille Viguier, Frédérique Deshayes, Nicolas Dulphy, Michael R Green, Ahmed Haouz, Fernando Rodrigues Lima
The Setd2 L1609p Mutation Found In Leukemia Disrupts Methyltransferase Activity And Reduces Histone H3k36 Trimethylation, Christina Michail, Jérémy Berthelet, Ariel E Mechaly, Linh-Chi Bui, Haopeng Yang, Duo Cai, Amira Al Mahi, Aowei Xie, Valeria Bisio, Valentina Sirri, Jean-Marie Dupret, Fabien Guidez, Ximing Xu, Nicolas Joly, Leslie Regad, Mireille Viguier, Frédérique Deshayes, Nicolas Dulphy, Michael R Green, Ahmed Haouz, Fernando Rodrigues Lima
Faculty, Staff and Student Publications
SETD2 is the primary methyltransferase responsible for generating H3K36me3, an epigenetic mark that is essential for transcriptional regulation and chromatin integrity. SETD2 mutations are frequently observed in various cancers and tend to cluster within its catalytic SET domain. Despite the clinical relevance of SETD2 missense mutations in cancer, their biochemical and structural consequences remain insufficiently characterized. Here, we present the enzymatic and structural characterization of the SETD2 L1609P mutant enzyme identified in leukemia. The L1609 residue is located in the SET domain within a conserved hydrophobic pocket that is involved in substrate H3K36 recognition. Interestingly, site-directed mutagenesis of residues within …
Mackenzie River Freshwater Controls Early Sea Ice Formation In The Eastern Beaufort Sea, M. J. Zahn, S. Fournier, I. G. Fenty, M. Steele, M. Wood, P. Gaube
Mackenzie River Freshwater Controls Early Sea Ice Formation In The Eastern Beaufort Sea, M. J. Zahn, S. Fournier, I. G. Fenty, M. Steele, M. Wood, P. Gaube
Faculty Research, Scholarly, and Creative Activity
Arctic sea ice plays a critical role in Earth's climate system, and as it continues to thin and retreat, understanding the processes driving its variability is increasingly important. Using satellite data and a coupled ocean–sea ice model, we examined how freshwater from the Mackenzie River influences fall sea ice formation in the Beaufort Sea. An “ice bridge” between the coast and offshore ice edge consistently forms over the river's freshwater plume, with its location and extent varying interannually with freshwater distribution. Regions influenced by the plume experienced sea ice onset an average of 3 weeks earlier than adjacent, saltier waters. …
College Student Perceptions Of Ai Teaching Assistants: Bridging Technology And Human Connection For Effective Learning Support, Sarah Steimel
College Student Perceptions Of Ai Teaching Assistants: Bridging Technology And Human Connection For Effective Learning Support, Sarah Steimel
International Journal of Teaching and Learning in Higher Education
This study examines college students’ perceptions of AI Teaching Assistants (AITAs) in higher education, focusing on their communication experiences and expectations. Using qualitative data from (n=89) open-ended survey responses, six key themes emerged, spanning differences in information processing, social interaction, and task efficiency. Students appreciated AITAs for their speed, availability, and potential to provide unbiased feedback, yet expressed concerns about accuracy and trustworthiness. While AITAs were seen as approachable for simple or low-stakes inquiries, students emphasized the importance of human instructors for complex, nuanced, or emotional support. The findings highlight a preference for maintaining human connections in education while leveraging …
Development And Initial Validation Of The Comprehensive Ai Integration Readiness Survey (Caiirs), Richard D. Amoako, Jennifer A. Morrow
Development And Initial Validation Of The Comprehensive Ai Integration Readiness Survey (Caiirs), Richard D. Amoako, Jennifer A. Morrow
International Journal of Teaching and Learning in Higher Education
Artificial intelligence (AI) has emerged as a transformative force in higher education, improving learning and optimizing administrative operations. However, the adoption and integration of AI in learning environments have received limited research attention until recently. Consequently, this research aimed to develop and validate a scale to assess readiness and preparedness among higher education faculty members for the integrative adoption of AI in learning and teaching practices. A nationwide survey was used to collect data from faculty at universities and colleges in the United States. The CAIIRS scale was developed after an extensive review of scholarly literature. Exploratory factor analysis was …
Tuktuit: Caribou, William L. Blizek, Monica Blizek
Tuktuit: Caribou, William L. Blizek, Monica Blizek
Journal of Religion & Film
This is a review of the short film, Tuktuit: Caribou (2026), directed by Lindsay Aksarniq McIntyre.
Taga, William L. Blizek, Monica Blizek
Taga, William L. Blizek, Monica Blizek
Journal of Religion & Film
This is a review of the short film, Taga (2026), directed by Jill Marie Sachs.
Together Forever, William L. Blizek, Monica Blizek
Together Forever, William L. Blizek, Monica Blizek
Journal of Religion & Film
This is a review of the short film, Together Forever (2026), directed by Gregory Barnes.
The Passenger In 12a, Cristopher G. Cando
The Passenger In 12a, Cristopher G. Cando
Night Flight: Online Literary Journal
This short story follows Mateo Alvarez, a TSA officer whose life has settled into a rigid routine, and Elena, a passenger beginning a new chapter in her life. Their brief interaction during a routine security screening becomes a quiet but meaningful exchange, which centers on kindness, memory, and the courage to move forward. As Elena carries her father's journal with her on a flight toward a new opportunity, Mateo is reflecting on the choices he has avoided and the life he has placed on pause. Through parallel perspectives, this story explores themes of transition, human connection, and the impact of …
Advances In 2025: The Year In Review, Richard Alweis, Elizabeth Mamo, Christina Goodermote
Advances In 2025: The Year In Review, Richard Alweis, Elizabeth Mamo, Christina Goodermote
Advances in Clinical Medical Research and Healthcare Delivery
No abstract provided.
Obesity As A Health Priority: Insights From Research Productivity In The Arab World, Rania Hammami, Mirvat Alsnag
Obesity As A Health Priority: Insights From Research Productivity In The Arab World, Rania Hammami, Mirvat Alsnag
Saudi Medical Journal
No abstract provided.
National Heart Center/Saudi Heart Association 2025 Guidelines For Cardiovascular Diseases Prevention And Risk Assessment, Jamilah S Alrahimi, Shukri M. Al Saif, Laith Hussain-Alkhateeb, Ali M. Albarrati, Owayed M. Alshammeri, Talal S. Alghamdi, Khalid A. Al Faraidy, Ada M Al-Qunaibet, Nada A. Alnaji, Rasha A. Alfawaz, Waleed M. Alharbi, Waleed A. Alhabeeb, Fahad M. Alnouri, Adel A. Tash
National Heart Center/Saudi Heart Association 2025 Guidelines For Cardiovascular Diseases Prevention And Risk Assessment, Jamilah S Alrahimi, Shukri M. Al Saif, Laith Hussain-Alkhateeb, Ali M. Albarrati, Owayed M. Alshammeri, Talal S. Alghamdi, Khalid A. Al Faraidy, Ada M Al-Qunaibet, Nada A. Alnaji, Rasha A. Alfawaz, Waleed M. Alharbi, Waleed A. Alhabeeb, Fahad M. Alnouri, Adel A. Tash
Saudi Medical Journal
Objectives: To develop an evidence-based clinical guideline for the prevention and management of cardiovascular diseases (CVDs) in Saudi Arabia, tailored to local epidemiology and healthcare needs.
Methods: A multidisciplinary task force comprising cardiologists, public health specialists, and epidemiologists from different healthcare sectors in Saudi Arabia developed the guideline. Evidence synthesis was based on a comprehensive literature review and adaptation of international guidelines, particularly the 2021 European Society of Cardiology recommendations, contextualized to the Saudi setting.
Results: The guideline provides recommendations for both primary and secondary CVD prevention. Primary prevention emphasizes risk assessment incorporating genetic, lifestyle, and clinical factors, as well …
From Text To Test: Pre-Lecture Reading Boosts Medical Students’ Comprehension And Retention, Hamad A. Alfahaad, Mohammed Y. Alasmary, Emad M. Masuadi, Mohi Eldin M. Magzoub, Henk G. Schmidt
From Text To Test: Pre-Lecture Reading Boosts Medical Students’ Comprehension And Retention, Hamad A. Alfahaad, Mohammed Y. Alasmary, Emad M. Masuadi, Mohi Eldin M. Magzoub, Henk G. Schmidt
Saudi Medical Journal
Objective: Medical students frequently attend lectures without prior review of the related literature when preparing for examinations. It raises the question of whether studying the material in advance could enhance their learning outcomes during lectures.
Methods: A total of 102 medical students from a Saudi Arabian university took part in this research. Participants were assigned to one of 2 cohorts: one read a 4-page passage before a 15-minute lecture, while the other attended the lecture before reading the passage. Knowledge acquisition was measured using a test that assessed their ability to recall concepts administered 3 times—prior to the session, post …
Medication Errors Reporting And Analysis: A Comparative Study For Advancing Medication Safety Practices In Ministry Of Health Hospitals In Saudi Arabia, Saleh A. Alghamdi
Medication Errors Reporting And Analysis: A Comparative Study For Advancing Medication Safety Practices In Ministry Of Health Hospitals In Saudi Arabia, Saleh A. Alghamdi
Saudi Medical Journal
Objectives: To analyze and compare these stages, types, frequency, causes, and corrective actions related to medication errors (MEs) reported in Ministry of Health (MOH) hospitals in Saudi Arabia, and thereby enhance medication safety through data driven decisions.
Methods: A retrospective cross-sectional study was conducted using ME reports submitted to the Saudi MOH national reporting system from January 2023 to December 2024.Data were collected from nine hospitals, covering medication involved, reporting personnel, level of harm and corrective actions. A novel stratification framework (NSF) was used to visualize emerging risks and protective trends. Statistical analyses were conducted using relative risk (RR), risk …
Research Productivity On Obesity In The Arab World: A Bibliometric Analysis (2004–2023), Jamil Adnan Samkari, Ahamd Azam Malik
Research Productivity On Obesity In The Arab World: A Bibliometric Analysis (2004–2023), Jamil Adnan Samkari, Ahamd Azam Malik
Saudi Medical Journal
Objective: To examine obesity research trends in Arab countries to inform policies and interventions.
Methods: A bibliometric analysis was conducted using the Web of Science database accessed via King Abdulaziz University’s electronic library. Publications on obesity research in Arab countries from 2004 to 2023 were analyzed using R-Bibliometrix. Key parameters included publication volume, leading authors and institutions, funding sources, keyword co-occurrence networks, and collaboration patterns.
Results: Obesity-related research output in Arab countries demonstrated consistent growth from 2004 to 2023, with a threefold increase in publications since 2015. Regional and international collaborations have intensified, although disparities in research productivity persist across …
Endovascular Thrombectomy For Acute Ischemic Stroke Among Stroke Patients In Jeddah, Saudi Arabia. A Retrospective Cohort Study (2024) Detailing Dual Center Experience, Abdullah M Alkutbi, Omar Abdulhamidayoub, Fawaz Mosaedalshareef, Mohammed M Alwadi, Rawan I Alqurashi, Rayan I Almaghrabi, Naif F Alharbi, Omar M Alhazmi, Ziad H Alzabidi, Nagham S Alsolaimani, Saher F Alqarni
Endovascular Thrombectomy For Acute Ischemic Stroke Among Stroke Patients In Jeddah, Saudi Arabia. A Retrospective Cohort Study (2024) Detailing Dual Center Experience, Abdullah M Alkutbi, Omar Abdulhamidayoub, Fawaz Mosaedalshareef, Mohammed M Alwadi, Rawan I Alqurashi, Rayan I Almaghrabi, Naif F Alharbi, Omar M Alhazmi, Ziad H Alzabidi, Nagham S Alsolaimani, Saher F Alqarni
Saudi Medical Journal
Background: Te evaluate the outcomes of Endovascular thrombectomy (EVT) -treated AIS patients in Jeddah, Saudi Arabia, and explores predictors of functional recovery. Endovascular thrombectomy (EVT) is the standard of care for acute ischemic stroke (AIS), though patient outcomes can vary based on regional and clinical factors.
Method: A retrospective cohort study was conducted using medical records from King Abdulaziz University Hospital (KAUH) and King Fahad Hospital Jeddah (KFHJ), including AIS patients treated with EVT between January 2020 and July 2024. Neurological status was assessed using the NIH Stroke Scale (NIHSS), and clinical outcomes were evaluated with the modified Rankin Scale …
Influence Of Metabolic Dysfunction-Associated Steatotic Liver Disease On Pattern And Management Of Acute Coronary Syndrome, Elshazly Abdulkhalik, Nagat Ibrahim, Selim Sidhom, Hesham H Alqurashi, Khaled Alghashmari, Muhammad Alotaibi, Ahmed Alqurashi, Moath Alzahrani, Shahad Alqahtani, Abdulaziz Alshalan, Nouran Althumali, Mazen Aljohani, Saud Alzahrani, Haidi Karam-Allah Ramadan
Influence Of Metabolic Dysfunction-Associated Steatotic Liver Disease On Pattern And Management Of Acute Coronary Syndrome, Elshazly Abdulkhalik, Nagat Ibrahim, Selim Sidhom, Hesham H Alqurashi, Khaled Alghashmari, Muhammad Alotaibi, Ahmed Alqurashi, Moath Alzahrani, Shahad Alqahtani, Abdulaziz Alshalan, Nouran Althumali, Mazen Aljohani, Saud Alzahrani, Haidi Karam-Allah Ramadan
Saudi Medical Journal
Objectives: To determine the influence of metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and hepatic fibrosis on the pattern and management of patients who had acute coronary syndrome (ACS).
Methods: Retrospective records of patients with ACS included demographic, electrocardiographic, and laboratory data of platelets count, glycated hemoglobin, lipogram, liver and cardiac enzymes. Ultrasound was used to evaluate fatty liver. Coronary angiography data included the number, site and percentage of the coronary arteries occluded. The type and outcome of treatment of ACS were recorded. Laboratory markers were measured to evaluate fibrosis.
Results: The study recruited 259 patients, and the majority were males. …
Juvenile Idiopathic Arthritis Registry At King Abdullah Specialized Children’S Hospital (Jiar-Kasch) In Riyadh, Saudi Arabia, Jubran T. Alqanatish, Abdullah I. Almojali, Wejdan M. Algbaiwi, Abdullah S. Alqahtani, Abdulrahman A. Alrasheed, Lubna A. Alnasser, Wafaa M. Alsuwairi
Juvenile Idiopathic Arthritis Registry At King Abdullah Specialized Children’S Hospital (Jiar-Kasch) In Riyadh, Saudi Arabia, Jubran T. Alqanatish, Abdullah I. Almojali, Wejdan M. Algbaiwi, Abdullah S. Alqahtani, Abdulrahman A. Alrasheed, Lubna A. Alnasser, Wafaa M. Alsuwairi
Saudi Medical Journal
Objectives: To establish and maintain a comprehensive, up-to-date registry of juvenile idiopathic arthritis (JIA) cases, and to outline the methodology used in creating it.
Methods: Retrospective and prospective data collection commenced in August 2021, using the Hospital Information System to identify electronic medical records of JIA patients. All individuals diagnosed with JIA and receiving follow-up care at King Abdullah Specialized Children’s Hospital (KASCH) in Riyadh were included. A broad range of variables covering sociodemographic characteristics, clinical features, laboratory results, imaging findings, and therapeutic medications were recorded in the REDCap platform. Data collection update occurs every 6 months.
Results: By December …
Clinical Characteristics And Outcomes Of Patients With Amphetamine Associated Emergency Department Visits At A Tertiary Care Hospital In Riyadh, Saudi Arabia, Mohammed K. Alsharef, Mahdi Almutairi, Nouf Ababtain, Mohammed Alajmi, Abdulrahman Alrajhi, Faisal Alhusain, Mohammad Al Deeb
Clinical Characteristics And Outcomes Of Patients With Amphetamine Associated Emergency Department Visits At A Tertiary Care Hospital In Riyadh, Saudi Arabia, Mohammed K. Alsharef, Mahdi Almutairi, Nouf Ababtain, Mohammed Alajmi, Abdulrahman Alrajhi, Faisal Alhusain, Mohammad Al Deeb
Saudi Medical Journal
Objective: To investigate the demographic and clinical profiles of patients presenting with amphetamine-related emergencies at a tertiary hospital in Riyadh, Saudi Arabia. Amphetamine use is an escalating public health issue linked to a rise in emergency department (ED) visits.
Methods: This retrospective study encompasses 14 years and focuses on individuals diagnosed with amphetamine-related toxicity.
Results: Among the 659 cases studied, a predominant 96% were male, with over half (52%) aged between 19 and 30 years. Most patients (91%) were Saudi nationals. The leading cause of presentation was trauma, accounting for 24% of cases. This was followed by altered mental status …
Targeted Neonatal Echocardiography And Neonatal Hemodynamics In The Kingdom Of Saudi Arabia: A One-Year Experience In Service Implementation, Abdulaziz Homedi, Kamal Ali Ali, Abdulrahman Almehaid, Mohanned Alrahili, Abdulrahman Mandurah, Mohammed Almahdi, Faisal Alamer, Eman Bazbouz, Shatha Algarni, Atheer Alshehri, Faisal Alsehli, Hanof Bakri
Targeted Neonatal Echocardiography And Neonatal Hemodynamics In The Kingdom Of Saudi Arabia: A One-Year Experience In Service Implementation, Abdulaziz Homedi, Kamal Ali Ali, Abdulrahman Almehaid, Mohanned Alrahili, Abdulrahman Mandurah, Mohammed Almahdi, Faisal Alamer, Eman Bazbouz, Shatha Algarni, Atheer Alshehri, Faisal Alsehli, Hanof Bakri
Saudi Medical Journal
Objective: To evaluate the impact of a newly established targeted neonatal echocardiography (TNE) and Neonatal Hemodynamics consultation service on the assessment and management of neonates.
Methods: This is a descriptive retrospective cohort study that included all neonates who underwent TNE consultations in the Neonatal Intensive Care Unit from October 2023 and September 2024. Clinical indications, diagnostic findings, and subsequent management were analyzed.
Results: A total of 237 TNE consultations were performed for 105 neonates. The mean gestational age was 29.9 weeks, and the mean birth weight was 1433 grams. On average, 19.8 echocardiographic scans were performed per month. The leading …
Gender Differences In Sociodemographic And Clinical Characteristics Of Methamphetamine Use In Saudi Arabia, Halima M. Adam, Mohamed Abouzed, Ahmed H. Aljadani, Benayan B. Alrasheedy, Muath A. Alarfaj, Salwa R. Alshammari, Mohamed S. Almuqahwi
Gender Differences In Sociodemographic And Clinical Characteristics Of Methamphetamine Use In Saudi Arabia, Halima M. Adam, Mohamed Abouzed, Ahmed H. Aljadani, Benayan B. Alrasheedy, Muath A. Alarfaj, Salwa R. Alshammari, Mohamed S. Almuqahwi
Saudi Medical Journal
Objectives: To explore gender-related variations in sociodemographic factors, clinical presentations, and psychosocial characteristics among methamphetamine users in Saudi Arabia.
Methods: A retrospective cross-sectional study was conducted using the electronic health records of 1,181 patients (91% male, 9% female) treated at multiple Erada Mental and Addiction Centers across Saudi Arabia (2020–2024). Data on sociodemographic characteristics, methamphetamine use patterns, psychiatric comorbidities, and psychosocial functioning were collected and analyzed using validated tools, including the Addiction Severity Index, Beck Depression and Anxiety Inventory, and Quality of Life Scale.
Results: Female participants were younger than males (mean age 25.3 vs 28.5 years; p < 0.001) and initiated methamphetamine at a later age (21.4 vs 19.2 years; p < 0.001). Females had greater proportion of daily use (65.4% vs. 60%, p …
Invasive Methicillin-Susceptible And Methicillin-Resistant Staphylococcus Aureus Infections In The Pediatric Population: Prevalence And Management Outcomes, Khalifa M. Binkhamis, Ibrahim A. Alhezam, Hassan A. Alabdullatif, Othman M. Alabdullah, Omar Y. Alkadhi, Nawaf M. Alrefaei, Abdullah S. Almayah, Fatema A. Juma, Sarah S. Alangari
Invasive Methicillin-Susceptible And Methicillin-Resistant Staphylococcus Aureus Infections In The Pediatric Population: Prevalence And Management Outcomes, Khalifa M. Binkhamis, Ibrahim A. Alhezam, Hassan A. Alabdullatif, Othman M. Alabdullah, Omar Y. Alkadhi, Nawaf M. Alrefaei, Abdullah S. Almayah, Fatema A. Juma, Sarah S. Alangari
Saudi Medical Journal
Objectives: Infections by invasive methicillin-resistant Staphylococcus aureus (MRSA) are associated with higher morbidity and mortality compared to methicillin-susceptible Staphylococcus aureus (MSSA) infections, and have increased significantly in both healthy children and children with chronic illnesses. In our study we aimed to estimate the prevalence of invasive MSSA and MRSA among invasive Staphylococcus aureus (S. aureus) infections in the pediatric population and measure the association between management outcomes and methicillin resistance in these infections.
Methods: We conducted an observational, analytical, retrospective cross-sectional, chart-review study of pediatric patients (aged ≤16 years) admitted to King Khalid University Hospital in Riyadh, Saudi Arabia …
Prevalence Of Autoimmune Thyroid Disease Among Individuals With Celiac Disease In A Primary Care Setting In Riyadh, Saudi Arabia, Mansour I. Alrasheed, Hussam Jnaid, Faisal K. Alrasheed, Tarfah R. Alsharidi, Abdulelah I. Alrasheed, Sarah A. Alobaid, Norah A. Sulaiman
Prevalence Of Autoimmune Thyroid Disease Among Individuals With Celiac Disease In A Primary Care Setting In Riyadh, Saudi Arabia, Mansour I. Alrasheed, Hussam Jnaid, Faisal K. Alrasheed, Tarfah R. Alsharidi, Abdulelah I. Alrasheed, Sarah A. Alobaid, Norah A. Sulaiman
Saudi Medical Journal
Objectives: Celiac disease (CD) is a prevalent autoimmune disorder triggered by gluten consumption, leading to an immune response that damages the small intestine. Research shows a link between CD and autoimmune thyroid disorders (AITD). This study seeks to determine the prevalence of AITD among adult and pediatric patients with CD in the primary care setting in Riyadh, Saudi Arabia.
Methods: A retrospective cross-sectional study reviewed electronic health records of individuals diagnosed with CD from January 2016 to December 2023 at King Faisal Specialist Hospital and Research Centre. Collected data encompassed patient demographics, diagnostic approaches, thyroid function assessments, thyroid autoantibody profiles, …
Magnitude Of Abdominal Solid Organs Injuries Among Patients With Pelvic Fracture At King Abdullah Hospital, Bisha City, Saudi Arabia, Ali Ibrahim Alshehri, Mohammed Jalawi Karkaman, Nawaf Amer Alsoiry, Naif Abdulaziz Alqarni
Magnitude Of Abdominal Solid Organs Injuries Among Patients With Pelvic Fracture At King Abdullah Hospital, Bisha City, Saudi Arabia, Ali Ibrahim Alshehri, Mohammed Jalawi Karkaman, Nawaf Amer Alsoiry, Naif Abdulaziz Alqarni
Saudi Medical Journal
Objective: To access the magnitude of these injuries in patients with pelvic fractures at King Abdullah Hospital, Bisha, Saudi Arabia. Abdominal solid organ injuries are life-threatening and results in adverse health effects particularly to patients with pelvic fracture.
Methods: An analytical cross-sectional retrospective hospital-based study that reviewed a total of 236 medical records of patients with abdominal organ injuries and pelvic fractures at King Abdullah Hospital, Bisha, Saudi Arabia. Cleaned data was coded and analyzed with the use of SPSS version 23 to drive key insights.
Results: The study comprised of 236 patients in total. Approximately 38 (16.1%) patients had …
Sphingosine-1-Phosphate Regulation To Alleviate Sickle Cell Disease Severity: A Promising Therapeutic Approach, Shahanas Chathoth
Sphingosine-1-Phosphate Regulation To Alleviate Sickle Cell Disease Severity: A Promising Therapeutic Approach, Shahanas Chathoth
Saudi Medical Journal
Sickle cell disease (SCD) is a genetic disorder that affects millions of individuals worldwide. Chronic anemia, hemolysis and vasculopathy are the most common symptoms that arise from hemoglobin (Hb) polymerization, which is the primary event of SCD. The above process can lead to erythrocyte sickling. Therapeutic options for SCD remain limited, and novel therapies are still being evaluated for their effectiveness in particular populations. Sphingosine-1-phosphate (S1P), a significant bioactive sphingolipid, acts as a potent signal mediator, modulating several cellular functions. The potential role of erythrocyte-S1P in enhancing SCD severity has been previously reported by multiple studies. Therefore, the present review …
Colorectal Cancer Screening In Saudi Arabia: Current Challenges And Future Directions, Abdulrahman A. Aljabri, Abdulrahman G. Alharbi
Colorectal Cancer Screening In Saudi Arabia: Current Challenges And Future Directions, Abdulrahman A. Aljabri, Abdulrahman G. Alharbi
Saudi Medical Journal
Colorectal cancer has become a major public health concern in Saudi Arabia. It is the most prevalent cancer among men and the third most prevalent among women. Although screening for people aged 45-75 is recommended by national recommendations, screening uptake is still below 10%, and less than 1% of older persons have a colonoscopy. With regional differences that vary from age-standardized rates of 3.2 per 100,000 in Jouf to 21.8 per 100,000 in Riyadh among men, approximately 29% of cases are detected at late stages. Therefore, we assessed the epidemiological, social, and health-related systemic structures preventing effective colorectal cancer screening …
Prevalence Of Carbapenem-Resistant Enterobacteriaceae In Intensive Care Units In Saudi Arabia: A 10-Year Systematic Review, Shadi A. Zakai
Prevalence Of Carbapenem-Resistant Enterobacteriaceae In Intensive Care Units In Saudi Arabia: A 10-Year Systematic Review, Shadi A. Zakai
Saudi Medical Journal
Objective: To synthesize research on the prevalence and distribution patterns of carbapenem-resistant Enterobacteriaceae (CRE) in Intensive Care Units (ICUs) across Saudi Arabia. It also seeks to evaluate molecular resistance profiles, identify associated risk factors, assess antimicrobial susceptibility, and examine infection control strategies within these critical care settings.
Methods: A systematic analysis was conducted, including cross-sectional, retrospective, and genomic studies from various tertiary hospitals in Saudi Arabia. The review focused on epidemiological trends, molecular characterization of CRE strains, clinical correlates, and the outcomes of implemented intervention strategies.
Results: The findings indicate a high and steadily increasing prevalence of CRE, often exceeding …