Digital Commons Network^™

Enhanced Dietary Monitoring Using Fecal Genomics For Childhood Malnutrition Interventions, Ammara Aqeel, Najeeha T Iqbal, Sanam Iram Soomro, Sheraz Ahmed, Teresa K Mcdonald, Olivia Osborne, Sharon Jiang, Nolan Ives, Kazi Ahsan, Fayaz Umrani, Michael J Barratt, Jeffrey I Gordon, Syed Asad Ali, Lawrence A David

2020-Current year OA Pubs

Ready-to-use therapeutic and supplementary foods (RUTF/RUSF) are a primary treatment for childhood malnutrition in Community Management of Acute Malnutrition (CMAM) programs. However, measuring intervention compliance is labor intensive and unreliable. We applied FoodSeq, a fecal genomic dietary assessment biomarker, in malnourished infants (3-15 months) from Matiari, Pakistan. FoodSeq identified a significant increase in the abundance of DNA from chickpea, a primary RUSF ingredient, during RUSF administration and captured region-specific complementary feeding practices, including age-inappropriate feeding practices such as wide-spread tea consumption. Our findings highlight the potential of dietary genomics as an empirical and scalable tool for compliance monitoring and dietary …

Alumna Turns Gratitude Into Opportunity For Journalism Students, Michael Newsom

University of Mississippi News

OXFORD, Miss. – As a broadcast journalism student at the University of Mississippi, Ashley Anderson Mattei spent late nights in the newsroom, learning by doing and making real decisions that mirror the demands of professional media leadership.

The Fate Of Atkins In A Post-Dobbs Era: How State Discretion Risks Harm To Intellectually Disabled And Black Defendants, Chole Quinn Sotomayor

Cardozo Journal of Equal Rights and Social Justice (ERSJ) Blog

The Supreme Court’s stance on the death penalty has evolved over time. In Furman v. Georgia, the Court held that the death penalty violated the Eighth Amendment, only to reinstate it in Gregg v. Georgia four years later.  As the Court continued to interpret “evolving standards of decency,” it later categorically barred the execution of defendants with an intellectual disability in Atkins v. Virginia.  To determine if an individual is intellectually disabled, they must demonstrate subaverage adaptive skills that existed before age eighteen.  The Court has also recognized that IQ scores carry a ±5 margin of error and has …

The Impact Of An Interactive Open Education Textbook For An Undergraduate Introductory Chemistry Course For Nonmajors, Erin Avram

Chemistry Faculty Publications

Reading informational text is a critical skill across most professions. Unfortunately, students are less likely to purchase the required course materials now compared to 2010. A free, interactive text was developed for an introductory chemistry course for non-STEM majors. This involved remixing existing texts and incorporating interactive activities to engage students during the learning process and provide opportunities for them to gauge their learning. Based on the results of a student survey, 82% of students reported that it was very important to them that the text was free and 80% of students who responded reported that they used the eText …

Modeling Bitcoin Dynamics Using Differential Equations, Boone M. Fleenor

Departmental Honors & Graduate Capstone Projects

In this thesis, we develop and analyze two nonlinear systems of ordinary differential equations to model Bitcoin price dynamics. Analytical techniques are used to obtain exact or approximate solutions where possible. Then, numerical simulations using a fourth-order Runge–Kutta method are employed to explore system behavior beyond analytically tractable regimes. Finally, model outputs are compared to historical Bitcoin price data using normalized and resampled time series. These results suggest that deterministic models can provide meaningful insight into the structural behavior of Bitcoin markets, while highlighting the need for stochastic or time-dependent extensions for more realistic modeling.

Hybrid Bermudagrass Dormancy Management In A Cool-Season Climate, Clarissa H. Peterson

Theses and Dissertations

Hybrid bermudagrass (Cynodon dactylon [L.] Pers. × C. transvaalensis Burtt Davy) (HBG) is a water efficient warm-season turfgrass increasingly adopted in cool-season and semi-arid regions due to climate change and the demand for reduced irrigation inputs. However, prolonged winter dormancy limits its visual quality (verdure) and seasonal performance. This thesis evaluated multiple management strategies to modify dormancy dynamics and improve off-season turf quality in a cool-season environment. Field experiments assessed the effects of growth covers, fertilizers, colorants, surfactants, organic acids, and overseeding with cool-season species on HBG dormancy over two seasons. Dormancy responses were quantified using normalized difference vegetation index …

Rooted In Service, Reaching For The Stars, Lucila Ojeda '26

Senior Presentation of Learning

My biggest takeaway from Bonner is to not be afraid to ask for help. Coming from out of state, the transition from a familiar community to somewhere completely foreign was scary. The kindness shown to me by the people at Bonner is something I will never forget. Do it scared and take the leap of faith in reaching out and building your community. Bonner will help you as much as they can, and I hope my service has reflected the support I have been so fortunate to receive.

Artificial Intelligence-Assisted Neuropharmacology: Reshaping Drug Discovery And Translational Strategies For Neurological Diseases ​, Pri̇yanka Rathee, Suni̇thi̇ Lohan, Sari̇ta Khatkar, Neelam Mali̇k, Esra Akkol, Renu Sehrawat, Pooja Rathee, Anurag Khatkar

Turkish Journal of Medical Sciences

The rapid expansion of data-driven technologies, particularly machine learning (ML) and artificial intelligence (AI), has substantially influenced biomedical research and drug discovery. In neuropharmacology, the availability of large-scale genomic, proteomic, chemical, and clinical datasets has stimulated the adoption of AI-based approaches to address persistent challenges in neurological drug development, including high attrition rates and the scarcity of disease-modifying therapies. Unlike prior reviews that broadly discuss AI applications in drug discovery or neurology, this narrative review focuses specifically on neuropharmacology, with an emphasis on translational relevance, disease-oriented examples, and real-world constraints. We critically examine the application of AI and ML across …

Impact Of Two Sedation Protocols On Cardiac Electrophysiology During Spinal Anesthesia ​, Selvi̇naz Durantaş, Burak Nalbant, Fatma Kavak Akelma, Gökhan Erdem, Abdulkadi̇r But

Turkish Journal of Medical Sciences

Background/aim: Perioperative factors such as anesthetic drugs, central blocks, surgical stress, pain, and anxiety can affect cardiac electrophysiology and increase the risk of arrhythmias. Arrhythmia susceptibility can be assessed using ventricular markers such as the QT interval (QT), heart rate-corrected QT interval (QTc), QT dispersion (QTd), time between peak and end of T wave (Tp–e), cardiac electrophysiologic balance index (iCEB), and heart rate-corrected index of cardiac electrophysiologic balance (iCEBc), obtained from noninvasive electrocardiography (ECG) data. This study compared the effects of propofol and dexmedetomidine sedation on these parameters in patients undergoing total knee arthroplasty performed under spinal anesthesia.

Materials and …

Analysis Of Calr-Mutated Essential Thrombocythemia As A Distinct Disease Entity Compared With Jak2 V617f-Mutated And Triple-Negative Patients ​, Gökhan Sami̇ Aydin, Eli̇f Aksoy, İpek Yönal Hi̇ndi̇lerden, Aynur Dağlar Aday, Emi̇ne Gültürk, Meli̇ha Nalçaci, Fehmi̇ Hi̇ndi̇lerden

Turkish Journal of Medical Sciences

Background/aim: Calreticulin (CALR) mutations in essential thrombocythemia (ET) are associated with younger age, higher platelet counts, and lower thrombosis rates. The present study analyzes the demographic, laboratory, and clinical features of the CALR mutation and its prognostic impact.

Materials and methods: The clinical impact of CALR mutations was assessed in 391 ET patients.

Results: CALR-mutation patients were more commonly male than JAK2 V617F-positive and triple-negative patients. Age at diagnosis was similar across all groups, although patients with type 2 CALR mutations were younger than those with nontype 1/nontype 2 mutations. Compared with JAK2 V617F-positive patients, CALR-mutation patients had lower leukocyte …

Comprehensive Profiling Of Gut Microbiota In Postmenopausal Osteoporosis ​, Gülsemi̇n Ertürk Çeli̇k, Sedat Yildiz, Münevver Aksoy Bektaş, Yaprak Engi̇n-Üstün

Turkish Journal of Medical Sciences

Background/aim: Osteoporosis is a multifactorial skeletal disease that predominantly affects postmenopausal women and is characterized by reduced bone mass and an increased risk of fractures. Growing evidence suggests that the gut microbiota plays a pivotal role in bone metabolism through immunological, endocrine, and metabolic pathways, forming the basis of the so-called gut– bone axis. This study aimed to characterize gut microbiota composition in postmenopausal women with osteoporosis compared with healthy controls.

Materials and methods: Forty postmenopausal women aged 55–65 years were classified into osteoporosis (n = 20) and healthy control (n = 20) groups based on dual-energy X-ray absorptiometry T-scores. …

"The Silence Of The Farms": Suppressing Speech And Trampling Transparency To Shield Big Ag, Erin Okuno

Texas A&M Law Review

Do you really know where your last meal came from and whether it was safe to eat? Most people are not aware of the often appalling conditions at agricultural production facilities (aptly known as “factory farms”), including worker injuries and abuse, contaminated food, and environmental pollution, as well as the horrific ways in which the animals are kept, raised, and slaughtered. In the face of these concerning conditions and alarmingly frequent food recalls—including millions of pounds of contaminated meat—it would seem prudent to increase transparency at factory farms, but historically, they have operated behind a shield of secrecy due to …

Asthma Data In Türkiye Between 2016 And 2022: A Nationwide Descriptive And Observational Study Covering The Entire Adult Population, Kurtuluş Aksu, Gürgün Tuğçe Vural Solak, Nai̇m Ata, Mustafa Hami̇dullah Türkkani, Mustafa Mahi̇r Ülgü, Şuayi̇p Bi̇ri̇nci̇, Funda Aksu

Turkish Journal of Medical Sciences

Background/aim: Determining the current burden of asthma in countries is important in the diagnosis and follow-up of asthma patients and for the development of national health policies. Our study aimed to clarify the epidemiological and clinical data regarding asthmatic adults in Türkiye.

Materials and methods: The study was designed as a nationwide descriptive, observational cross-sectional study. Data on adult patients who were followed with the diagnosis of asthma in all public, private, and university hospitals in Türkiye between January 2016 and December 2022 were obtained from the e-Nabız database of the Ministry of Health and analyzed.

Results: The number of …

Quantum Scattering Of Hc5n And Para-H2 On A New Potential Energy Surface, Shan Gao, François Lique, Ernesto Quintas-Sánchez, Richard Dawes, Jérôme Loreau

Chemistry Faculty Research & Creative Works

In the interstellar medium (ISM), non-local thermodynamic equilibrium situations are common due to low density, and one needs to consider the effect of molecular collisions in order to interpret the observations. Among the species detected in the ISM, cyanopolyynes, with the general molecular formula HC_2n+1N (n = 1, 2, …), are characterized by large dipole moments and small rotational constants and constitute an indispensable class of candidates for the sensitive tracers of local density and temperature. We present a study of the collisional (de-) excitation of HC₅N by para-H₂ (p-H₂) in its ground …

Ucc Minutes 4-14-26, Angela Brock

UCC Agendas/Minutes

No abstract provided.

Approved Courses 4-14-26, Angela Brock

Individual Course Committee (ICC)

No abstract provided.

An Education Project To Address Pain Management Solutions For Adult Clients With Ue Involvement To Reduce Dependence On Pharmacological Options To Increase Comfort And Performance With Life Activities, Alexander J. Birdsall

Student Capstone Papers

Upper extremity (UE) pain affects approximately 30.7% of adults in the United States and is associated with decreased function and participation. Despite evidence supporting non-pharmacological approaches, pharmacological interventions remain commonly used. This capstone project implemented and evaluated an occupation-based educational program to promote non-pharmacological pain management among adults receiving outpatient occupational therapy for UE conditions. This 14-week project included 10 participants and utilized a mixed-methods design with pre-, mid-, and post-surveys. The program consisted of an introduction and three modules addressing therapeutic movement, physical agent modalities, and sensory regulation. Outcome measures included pain, activity engagement, medication use, confidence, and program …

Acute Compartment Syndrome Following Lower Leg Vascular Injury: A Big-Data Approach To Estimating Incidence And Risk Factors, Harry Moroz, Edward J. Harvey, Yasser C. Bouklouch

Journal of Shock and Hemodynamics

Acute Compartment Syndrome (ACS) is a limb- and life-threatening complication of lower leg fractures. Rapid recognition and fasciotomy can prevent irreversible ischemic injury, but ACS is often under-recognized. Vascular injury may increase the risk of ACS by impairing perfusion and exacerbating swelling. This study aimed to determine the incidence, risk factors, and outcomes of ACS in patients with lower leg fractures, with particular emphasis on the impact of vascular injury. This retrospective cohort study used data from the 2017 American College of Surgeons Trauma Quality Programs database to perform a multicenter analysis of patients with lower leg fractures. Patients were …

Dapk2 Regulates Pkm2 Phosphorylation At Threonine 45 To Facilitate Disturbed Flow-Induced Atherosclerosis, Shuai Guo, Long Xu, Yixin Chen, Yuan Zhao, Yuting Zhang, Runfa Yu, Kaixiang Cao, Litao Wang, Wenjia Ai, Jiang-Yun Luo, Lu Lu, Jun He, Yuan Zhou, Li Wang, Andrew H Baker, Yuqing Huo, Yiming Xu

Faculty, Staff and Students Publications

Background: Oscillatory shear stress (OSS), resulting from disturbed blood flow, is implicated in atherosclerotic plaque formation by incompletely understood mechanisms. This study aims to elucidate the involvement of death-associated protein kinase (DAPK) 2 in OSS-induced endothelial cell (EC) activation and atherosclerosis.

Methods: Publicly available resources, including genome-wide microarray, RNA sequencing, and single-cell RNA sequencing, were utilized to identify key OSS-sensitive regulatory factors. Techniques such as mass spectrometry, immunoprecipitation, proximity ligation assay, and RNA sequencing were employed to identify pyruvate kinase M2 (PKM2) as the binding protein of DAPK2 and determine the specific site of PKM2 phosphorylation by DAPK2. To assess …

Spiral: Communicating Using Climate Change Information, Lauralynn Montefrio Corrales, Joyce Claire Lau, Tamanna Sahoo

SPIRaL Undergraduate Research Projects

Our study highlights the importance of information literacy, specifically utilizing information about climate change. This study used a qualitative research framework that examined Purdue students who are highly engaged in talking about climate change information with others. Participants were identified through a screening questionnaire designed to assess levels of engagement with climate change information; the questionnaire was then utilized to sample participants, identifying those who confidently identified as being very engaged with climate change information. Semi-structured interviews were conducted with selected participants to obtain a thorough perspective of their experiences and viewpoints. Within each of these interviews, open-ended questions inquired …

Sbw 3.0: A Blockchain-Enabled Framework For Secure And Efficient Information Management In Web 3.0, Md Arif Hassan, Bui Duc Manh, Cong T. Nguyen, Chi-Hieu Nguyen, Dinh Thai Hoang, Diep N. Nguyen, Nguyen Van Huynh, Dusit Niyato

Staff Scholarship - Australia & Dubai

In this paper, we propose an effective blockchain-enabled information management framework, named Smart Blockchain-based Web 3.0 (SBW 3.0). Our framework aims to handle information within Web 3.0 efficiently, enhance data security and privacy, create new revenue streams, and encourage users to contribute valuable information to websites. To this end, SBW 3.0 employs blockchain technology and smart contracts to manage the decentralized data collection in Web 3.0. Moreover, we introduce a robust consensus mechanism grounded in Delegated Proof-of-Stake (DPoS) to reward user contributions. Furthermore, we develop a non-cooperative game model to examine user behavior in this context and conduct thorough analysis …

Advancing Hand Therapy Practice Through Specialized Clinical Reasoning And Patient Education, Candace Heinlein

Capstone Projects

This doctoral capstone experience (DCE) was completed at Corewell Health Grand Rapids Hospitals Hand Therapy Clinic and focused on two ACOTE concentration areas including advanced clinical practice skills and education. The experience combined hands-on clinical practice in a specialized outpatient hand therapy setting with the development of high-quality client education materials and home exercise programs (HEPs). Objectives were created to address identified needs through the creation of client education handouts, development of diagnosis-specific Medbridge HEP templates, and creation of training resources to improve therapist efficiency with Medbridge use. Outcomes of the project included improved access to evidence-based educational materials, reduced …

Mastery By Mistakes: Reframing Failure In Higher Education Skill-Based Teaching And Assessment, Maura Metheny

JWU Dissertations & Theses

Experiencing a mistake, error or failure while learning generates an additional inquiry process that activates prior knowledge and increases retention of subsequent feedback and new material (Kapur, 2008). The use of errors to guide practice has been shown to lead to skill-mastery and expertise (Ericsson et al., 1993). When classrooms are psychologically safe environments where penalty-free exploration and knowledge application are encouraged, students gain a deeper understanding of the content (Tulis, 2013). This qualitative exploratory descriptive study aimed to understand the ways that undergraduate faculty in skill-based disciplines involve errors, mistakes and failures in teaching and …

Safety And Efficacy Of Ciltacabtagene Autoleucel For Relapsed/Refractory Multiple Myeloma: A Cibmtr Study., Doris K Hansen, Danai Dima, Hira Mian, Jakob Devos, Ruta Brazauskas, Temitope Oloyede, Aimaz Afrough, Nausheen Ahmed, Larry Anderson, Rahul Banerjee, Jesus G Berdeja, Aram Bidikian, Binod Dhakal, Ajoy Dias, Yvonne Efebera, Muhammad Salman Faisal, Lohith Gowda, Hamza Hashmi, Abu-Sayeef Mirza, Meera Mohan, Ravi Narra, Ashley E Rosko, Mark Schroeder, Taiga Nishihori, Heather Landau, Saad Usmani, Marcelo C Pasquini, Othman S Akhtar, Surbhi Sidana, Krina K Patel

Oncology Articles

Ciltacabtagene autoleucel (cilta-cel), an anti-B-cell maturation antigen (BCMA) chimeric antigen receptor T-cell (CAR-T) therapy, was approved in 2022 for heavily pretreated relapsed/refractory multiple myeloma (RRMM). This study evaluates the safety and efficacy of cilta-cel in RRMM patients reported to the Center for International Blood and Marrow Transplant Research registry between March 2022 and December 2023 who met commercial release specifications. Among 595 patients, median age was 64 years, 57% were male, and 70% had ≥1 comorbidity. Extramedullary disease and marrow plasma cell burden ≥ 50% were present in 13% and 14% of patients, respectively. The median number of prior lines …

Semiochemicals And Odorant Receptors Underlying Potato Cultivar Susceptibility And Resistance To Potato Tuber Moth, Ruipeng Chen, Wangtao Hu, Qin Hu, Junjie Yan, Jiao Yin, Fathiya M. Khamis, Yulin Gao, Walter S. Leal

All Peer-Reviewed Publications

Infestation of potato by the potato tuber moth (Phthorimaea operculella) varies markedly among cultivars, yet the chemical and molecular mechanisms underlying this variation remain poorly understood. Here, we combine field surveys, chemical ecology, functional genomics, and structural modeling to reveal how cultivar-specific volatile profiles shape moth oviposition behavior and pest outcomes. Field and laboratory assays identified marked differences in adult attraction, oviposition, and larval damage among potato cultivars, which correlated with distinct blends of emitted volatile organic compounds (VOCs). Behavioral analyses revealed that among other VOCs, trans-nerolidol and β-ionone act as attractants, whereas 3-carene and benzyl tiglate function as oviposition …

Knowledge, Attitude And Practice Towards Sarcopenia Among Diabetic Patients Attending Outpatient Department Of A Tertiary Care Centre In Kerala, India, Vysakh Ts, Ajas Sn, Asha Raby N

Muthanna Medical Journal

Background: Sarcopenia is a progressive skeletal muscle disorder increasingly seen in individuals with diabetes, leading to functional decline and poor quality of life. Despite Kerala's high diabetes burden, sarcopenia remains underrecognized. This study assessed knowledge, attitude, and practice (KAP) regarding sarcopenia among diabetic patients and examined inter-domain relationships. Methods: A 6-month institutional cross-sectional study was conducted in the Family Medicine outpatient department of St. Joseph's Hospital Trust, Kochi. Using consecutive sampling, 154 diabetic patients (type 1 or 2) aged ≥ 40 years were enrolled. Data were collected using a pilot-tested questionnaire covering sociodemographic and clinical details, knowledge (12 items), attitude …

Regulatory Role Of Il-1Β And Cxcl8 In Inflammatory Cell Dynamics And Gingival Inflammation In Gingivitis, Dhuha Mahmood Ali

Muthanna Medical Journal

Background: Gingivitis is a common inflammatory disease of the periodontal tissues characterized by immune responses triggered by microbial biofilm. The inflammatory process involves the release of several cytokines and chemokines, including interleukin-1 beta (IL-1β ) and chemokine CXCL8, which play crucial roles in regulating leukocyte recruitment and inflammatory signaling within the gingival tissues. These biomarkers are considered important indicators of periodontal inflammation and may reflect the progression of periodontal diseases.

Aim: This study aimed to evaluate the levels of inflammatory biomarkers IL-1β and CXCL8 and investigate their role in gingival inflammation.

Materials and Methods: This case-control study included subjects diagnosed …

Prevalence And Clinical Significance Of Anti-A And Anti-B Haemolysins In Group O Voluntary Blood Donors: A Cross-Sectional Laboratory-Based Study From South India, Resmi T Mony

Muthanna Medical Journal

Background: Group O blood donors are considered universal red-cell donors due to the absence of A and B antigens on erythrocytes. However, their plasma contains naturally occurring anti-A and anti-B isoagglutinins, which may exhibit complement-mediated haemolytic activity. Transfusion of plasma-containing components from such donors to non-O recipients-especially platelets or large plasma volumes—can result in passive haemolytic transfusion reactions. Data on the prevalence of high haemolytic potential in South India remain limited. Methods: This observational cross-sectional laboratory-based study was conducted from November 2017 to November 2019 at the blood bank of Sree Gokulam Medical College, Thiruvananthapuram, Kerala. A total of 106 …

Severe Autoimmune Digital Vasculopathy In Systemic Sclerosis With Lupus- And Antiphospholipid-Spectrum Serologic Positivity And Libman–Sacks Endocarditis: A Case Report, Mayada F. Bawayan, Thekra A. Alwafi, Abdulaziz F. Samandar, Abdulaziz M. Gari

Saudi Toxicology Journal

Background: Systemic sclerosis (SSc) is an autoimmune connective tissue disease characterized by prominent vasculopathy, which may lead to severe digital ischemia and ulceration. The coexistence of SSc-related vasculopathy with lupus- and antiphospholipid-spectrum manifestations, including Libman–Sacks endocarditis, is uncommon and poses diagnostic and therapeutic challenges. Case Presentation: We report a 37-year-old female with a systemic sclerosis phenotype and overlapping lupus- and antiphospholipid-spectrum features, who presented with severe bilateral digital ischemia and ulceration. Investigations revealed active autoimmune disease with inflammatory, immunologic, and vascular involvement, along with Libman–Sacks endocarditis. Imaging excluded large-vessel occlusive disease. The patient was treated with targeted vasodilator therapy and …

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