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Democratizing National Water Model Streamflow Forecasts Through Cross-Platform Mobile Application Development, Jerson J. Garcia Apr 2026

Democratizing National Water Model Streamflow Forecasts Through Cross-Platform Mobile Application Development, Jerson J. Garcia

Theses and Dissertations

The National Water Model (NWM) provides operational streamflow forecasts for 2.7 million stream reaches across the continental United States, yet technical barriers prevent widespread public access to this hydrological infrastructure. This paper presents RIVR (River Information Visualization and Risk), a cross-platform mobile application that transforms National Water Model forecasts into an accessible interface for non-technical users. Built with Flutter, the application deploys to iOS and Android from a single codebase and integrates NOAA forecast APIs, CIROH return-period thresholds, and interactive vector-tile mapping. Performance evaluation across six metrics: application size, startup time, memory consumption, rendering frame rates, API response times, and …


Prognostic Significance And Clinicopathological Associations Of Tumor Budding And Poorly Differentiated Clusters In Endometrioid Endometrial Carcinoma ​, Hani̇fe Seda Mavi̇li̇, Ömer Atmiş, Fatma Seher Pehli̇van, Fatma Sezen Çavdaroğlu Deveci̇, Ali̇ Riza Kandi̇loğlu Apr 2026

Prognostic Significance And Clinicopathological Associations Of Tumor Budding And Poorly Differentiated Clusters In Endometrioid Endometrial Carcinoma ​, Hani̇fe Seda Mavi̇li̇, Ömer Atmiş, Fatma Seher Pehli̇van, Fatma Sezen Çavdaroğlu Deveci̇, Ali̇ Riza Kandi̇loğlu

Turkish Journal of Medical Sciences

Background/aim: Tumor budding (TB) and poorly differentiated clusters (PDCs) are histopathological parameters that have been associated with poor prognosis in various malignancies, particularly colorectal carcinoma. Although numerous studies have demonstrated an association between the microcystic, elongated, and fragmented (MELF) pattern in endometrial carcinomas and lymphovascular invasion as well as lymph node metastasis, the literature regarding TB and PDCs in this context remains limited. This study aimed to investigate the potential associations of the MELF pattern, TB, and PDCs with overall survival, progression-free survival, and clinicopathological parameters in cases of endometrioid endometrial carcinoma (EEC).

Materials and methods: A total of 190 …


Advanced Carcinoid Heart Disease: A Case Of Fatal Postoperative Shock, Gongkai Liu, Saad Masud, Sarita Thanedar Apr 2026

Advanced Carcinoid Heart Disease: A Case Of Fatal Postoperative Shock, Gongkai Liu, Saad Masud, Sarita Thanedar

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


The Unusual Suspects: A Rare Presentation Of Waterhouse-Friderichsen Syndrome, Nafis Deen, Nawsin Baset, Bravein Amalakuhan Apr 2026

The Unusual Suspects: A Rare Presentation Of Waterhouse-Friderichsen Syndrome, Nafis Deen, Nawsin Baset, Bravein Amalakuhan

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Colo-Ovarian Fistula Presenting As Tubo-Ovarian Abscess, Jessica Harper, Michelle Mieles, Kyle Biggs Apr 2026

Colo-Ovarian Fistula Presenting As Tubo-Ovarian Abscess, Jessica Harper, Michelle Mieles, Kyle Biggs

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Views, Knowledge, And Implications Of Abortion Law In Texas Obgyn Residencies, Jessica Harper, Sharon Barazani, Kate Mowry, Melissa Mendez Apr 2026

Views, Knowledge, And Implications Of Abortion Law In Texas Obgyn Residencies, Jessica Harper, Sharon Barazani, Kate Mowry, Melissa Mendez

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Mycobacterial Soft Tissue Infection Following Gluteal Fat Grafting: A Case Report And Review Of Surgical Asepsis Implications, Sophia Ahmed, Chandra Ellis Apr 2026

Mycobacterial Soft Tissue Infection Following Gluteal Fat Grafting: A Case Report And Review Of Surgical Asepsis Implications, Sophia Ahmed, Chandra Ellis

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Progressive Neuropathy With Normal Vitamin B12 Levels And Demyelinating Findings, Michael Rollins, Juan Rodriguez, Laura Preece Apr 2026

Progressive Neuropathy With Normal Vitamin B12 Levels And Demyelinating Findings, Michael Rollins, Juan Rodriguez, Laura Preece

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Are You My Doctor? Impact Of Role Identification Badges In Improving Resident Experience, Rasmeet Kaur, Laura Preece Apr 2026

Are You My Doctor? Impact Of Role Identification Badges In Improving Resident Experience, Rasmeet Kaur, Laura Preece

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Recurrent Molar Pregnancy – A Case Report, Jayce Jaynes, Sarina Garcia, Dorovenia Hawkins-Koch Apr 2026

Recurrent Molar Pregnancy – A Case Report, Jayce Jaynes, Sarina Garcia, Dorovenia Hawkins-Koch

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Hip Strengthening Exercises That Improve The Sit-To-Stand In Older Adults, Savanna Pohly Apr 2026

Hip Strengthening Exercises That Improve The Sit-To-Stand In Older Adults, Savanna Pohly

Doctorate in Kinesiology

To date, no home-based exercise programs have been established as definitive interventions for improving the sit-to-stand (STS) performance in older adults (OAs). Previous research identifies a duration of >15 seconds on the Five-Time-Sit-to-Stand Test (FTSST) as a significant predictor of increased fall risk for OAs. This study applies higher-ranked gluteal activation therapeutic exercises that can improve STS performance for OAs.

Twenty-five OAs age 72.68 ± 4.02 years old were given a 6-week home exercise program that included five therapeutic exercises to be performed three times a week using a Perform Better resistance loop. The FTSST and surveys were completed pre- …


Biomechanical Analysis Of Skeletal Open Bite Treatment Methods: A Comparative Finite Element Study ​, Ömer Faruk Sari, Muhammed Hi̇lmi̇ Buyukcavus Apr 2026

Biomechanical Analysis Of Skeletal Open Bite Treatment Methods: A Comparative Finite Element Study ​, Ömer Faruk Sari, Muhammed Hi̇lmi̇ Buyukcavus

Turkish Journal of Medical Sciences

Background/aim: The biomechanical effects of zygomatic anchorage plates, vertical chin-caps, and occipital headgear on dentofacial structures in patients with skeletal anterior open bite malocclusion were compared using three-dimensional finite element analysis.

Materials and methods: Three-dimensional finite element models were constructed based on computed tomography data obtained from a patient with skeletal anterior open bite. Simulation models representing zygomatic anchorage-supported intrusion, vertical chin-cap, and occipital headgear were generated under fixed orthodontic conditions. In each scenario, a unilateral force of 200 g (1.96 N) was applied along clinically relevant force vectors. Stress distributions in craniofacial bones, sutural structures, teeth, roots, and temporomandibular …


Effects Of Colchicine On Sah-Induced Vascular Damage In An Experimental Subarachnoid Hemorrhage Model ​, Emi̇ne Demi̇r, Cumaali̇ Demi̇rtaş, Cansu Sönmez, Eray Meti̇n Güler, Sarper Kocaoğlu, Hakan Beyaztaş, Eyüp Çeti̇n Apr 2026

Effects Of Colchicine On Sah-Induced Vascular Damage In An Experimental Subarachnoid Hemorrhage Model ​, Emi̇ne Demi̇r, Cumaali̇ Demi̇rtaş, Cansu Sönmez, Eray Meti̇n Güler, Sarper Kocaoğlu, Hakan Beyaztaş, Eyüp Çeti̇n

Turkish Journal of Medical Sciences

Background/aim: Subarachnoid hemorrhage (SAH) is a severe cerebrovascular condition associated with high morbidity and mortality. Inflammation and oxidative stress play critical roles in its pathophysiology, especially in the development of secondary vascular damage. This study aimed to evaluate the protective effects of colchicine on vascular integrity and biochemical markers following SAH in an experimental rat model.

Materials and methods: Eighteen female Sprague Dawley rats were randomly divided into 3 groups: Control (no SAH), SAH (induced without treatment), and SAH + colchicine (received intraperitoneal colchicine at a dose of 1 mg/kg). SAH was induced by injecting autologous blood into the cisterna …


Post-Exposure Prophylaxis For Hiv Among Healthcare Workers In Türkiye: A Descriptive, Multicenter Retrospective Study, Veysel Akca, İlkay Akbulut, Gül Ruhsar Yilmaz, Alper Tahmaz, Nefi̇se Öztoprak Çuvalci, İlknur Esen Yildiz, Mehmet Çabalak, Şeyma Topal, Özgür Günal, Bi̇rcan Kayaaslan, Fatma Eser, Tuba Damar Çakirca, Deni̇z Özer, Ali̇ye Baştuğ, Fi̇rdevs Aksoy, Hani̇fe Nur Karakoç Parlayan, Beyza Süllü, Damla Verendağ, Hatun Öztürk Çeri̇k, Mehmet Ali̇ Aşan, Ayhan Akbulut, Gülden Eser Karlidağ, Behi̇ce Kurtaran, Hüsnü Pullukçu, Turhan Togan Apr 2026

Post-Exposure Prophylaxis For Hiv Among Healthcare Workers In Türkiye: A Descriptive, Multicenter Retrospective Study, Veysel Akca, İlkay Akbulut, Gül Ruhsar Yilmaz, Alper Tahmaz, Nefi̇se Öztoprak Çuvalci, İlknur Esen Yildiz, Mehmet Çabalak, Şeyma Topal, Özgür Günal, Bi̇rcan Kayaaslan, Fatma Eser, Tuba Damar Çakirca, Deni̇z Özer, Ali̇ye Baştuğ, Fi̇rdevs Aksoy, Hani̇fe Nur Karakoç Parlayan, Beyza Süllü, Damla Verendağ, Hatun Öztürk Çeri̇k, Mehmet Ali̇ Aşan, Ayhan Akbulut, Gülden Eser Karlidağ, Behi̇ce Kurtaran, Hüsnü Pullukçu, Turhan Togan

Turkish Journal of Medical Sciences

Background/aim: Post-exposure prophylaxis (PEP) for human immunodeficiency virus (HIV) plays a vital role in preventing transmission among healthcare workers following occupational exposure. Despite its clinical importance, epidemiological data regarding PEP implementation in Türkiye remain scarce. This study aimed to assess PEP practices, prophylactic treatment regimens, and follow-up outcomes among healthcare workers at risk of occupational HIV exposure.

Materials and methods: This retrospective, multicenter study was conducted between January 2020 and December 2024 across 16 healthcare facilities participating in the National HIV/AIDS Working Group. Healthcare workers aged 18 years and older who presented for evaluation following occupational exposure to HIV were …


Language And Emotional Experience: A Worldwide Study, Natalie Lorange, Chelsea Romney Apr 2026

Language And Emotional Experience: A Worldwide Study, Natalie Lorange, Chelsea Romney

FHSS Mentored Research Conference

This qualitative study explored how native language influences emotional experience. Fourteen participants from diverse countries were recruited to capture a range of linguistic perspectives and experiences. Data were analyzed using thematic analysis, resulting in four key themes: (1) shared experience as central in creating emotional meaning, (2) the power of words in shaping emotional experience, (3) stronger emotional resonance in native or frequently used languages, and (4) the importance of regional differences in emotional experience. Findings suggest that while emotions may be largely universal, linguistic and cultural differences play a significant role in an individual's emotional identity. The study highlights …


Imsaloquium 2026 Event Booklet, Student Inquiry And Research (Sir) Apr 2026

Imsaloquium 2026 Event Booklet, Student Inquiry And Research (Sir)

IMSAloquium Event Booklets

Cover designed by Joyce Symoniak.

Welcome to IMSAloquium, our annual, school-wide symposium for research and inquiry! This booklet contains abstracts for over 220 outstanding projects conducted by IMSA students in the 2025-26 academic year. The topics range from biomedical research to artificial intelligence, from history to the social sciences, and from business to entrepreneurship. Many of our students are working with off-campus mentors at world-renowned universities, research laboratories, and businesses. Others are working on-campus with IMSA’s own outstanding Faculty. The SIR and IN2 Teams would like to thank all of our mentors for their efforts. Our experiential programs would not …


Clinical Applications Of Topical Platelet-Rich Plasma In Cardiac Surgery: A Scoping Review, Jaron M. Davis Apr 2026

Clinical Applications Of Topical Platelet-Rich Plasma In Cardiac Surgery: A Scoping Review, Jaron M. Davis

Student Works

Background: Postoperative wound complications persist as a significant challenge within adult cardiac surgery. Deep and superficial sternal wound infections, along with complications at saphenous vein harvest sites, are linked to increased morbidity, extended hospital stays, and substantial healthcare expenses. Topical platelet-rich plasma (PRP), commonly known as platelet gel, has been suggested as a biologically active adjunct that may facilitate tissue repair and mitigate postoperative complications. While PRP has garnered attention in surgical practice, the overall scope and consistency of the supporting evidence in cardiac surgery remain ambiguous.

Objective: The purpose of this scoping review is to map and describe the …


Sulfuric Acid Mist Generation, Calculation, And Suppression Mechanism And Methods In Electrowinning: A Review, Ashish Kakoria, Mirza Muhammad Zaid, Guang Xu Apr 2026

Sulfuric Acid Mist Generation, Calculation, And Suppression Mechanism And Methods In Electrowinning: A Review, Ashish Kakoria, Mirza Muhammad Zaid, Guang Xu

Mining Engineering Faculty Research & Creative Works

This review discusses the events of acid mist production at the final stage of hydrometallurgical metal production in copper electrowinning. This review entails the complete process of oxygen bubble generation on the anode and its stages to form into acid mist at the surface of the electrolyte. When these bubbles burst at the solution/air interface, fine acid-containing liquid droplets become airborne and spread throughout the workspace, with the impact factors suppressing the acid mist produced during the process. Also, parameters such as bubble size, temperature, surface tension, and visco-elasticity also affect the acid mist. Sulfuric acid affects the tank houses …


2026 Academic & Creative Excellence Reception Program, Lynn University Apr 2026

2026 Academic & Creative Excellence Reception Program, Lynn University

Academic and Creative Excellence (ACE) Reception Programs

The program for the 2026 Academic and Creative Excellence (ACE) Reception - the 18th annual - organized by the Lynn Library, working in conjunction with the Office of Academic Affairs. The reception was held Tuesday, April 14 in the Salon at the Keith C. and Elaine Johnson Wold Performing Arts Center.

The Faculty Scholarship and Creative Activities Award is presented to Dr. Roberta Rust.


Spartan Daily, April 14, 2026, San Jose State University, School Of Journalism And Mass Communications Apr 2026

Spartan Daily, April 14, 2026, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2026

Volume 166, Issue 32


Enhanced Dietary Monitoring Using Fecal Genomics For Childhood Malnutrition Interventions, Ammara Aqeel, Najeeha T Iqbal, Sanam Iram Soomro, Sheraz Ahmed, Teresa K Mcdonald, Olivia Osborne, Sharon Jiang, Nolan Ives, Kazi Ahsan, Fayaz Umrani, Michael J Barratt, Jeffrey I Gordon, Syed Asad Ali, Lawrence A David Apr 2026

Enhanced Dietary Monitoring Using Fecal Genomics For Childhood Malnutrition Interventions, Ammara Aqeel, Najeeha T Iqbal, Sanam Iram Soomro, Sheraz Ahmed, Teresa K Mcdonald, Olivia Osborne, Sharon Jiang, Nolan Ives, Kazi Ahsan, Fayaz Umrani, Michael J Barratt, Jeffrey I Gordon, Syed Asad Ali, Lawrence A David

2020-Current year OA Pubs

Ready-to-use therapeutic and supplementary foods (RUTF/RUSF) are a primary treatment for childhood malnutrition in Community Management of Acute Malnutrition (CMAM) programs. However, measuring intervention compliance is labor intensive and unreliable. We applied FoodSeq, a fecal genomic dietary assessment biomarker, in malnourished infants (3-15 months) from Matiari, Pakistan. FoodSeq identified a significant increase in the abundance of DNA from chickpea, a primary RUSF ingredient, during RUSF administration and captured region-specific complementary feeding practices, including age-inappropriate feeding practices such as wide-spread tea consumption. Our findings highlight the potential of dietary genomics as an empirical and scalable tool for compliance monitoring and dietary …


Alumna Turns Gratitude Into Opportunity For Journalism Students, Michael Newsom Apr 2026

Alumna Turns Gratitude Into Opportunity For Journalism Students, Michael Newsom

University of Mississippi News

OXFORD, Miss. – As a broadcast journalism student at the University of Mississippi, Ashley Anderson Mattei spent late nights in the newsroom, learning by doing and making real decisions that mirror the demands of professional media leadership.


The Fate Of Atkins In A Post-Dobbs Era: How State Discretion Risks Harm To Intellectually Disabled And Black Defendants, Chole Quinn Sotomayor Apr 2026

The Fate Of Atkins In A Post-Dobbs Era: How State Discretion Risks Harm To Intellectually Disabled And Black Defendants, Chole Quinn Sotomayor

Cardozo Journal of Equal Rights and Social Justice (ERSJ) Blog

The Supreme Court’s stance on the death penalty has evolved over time. In Furman v. Georgia, the Court held that the death penalty violated the Eighth Amendment, only to reinstate it in Gregg v. Georgia four years later.  As the Court continued to interpret “evolving standards of decency,” it later categorically barred the execution of defendants with an intellectual disability in Atkins v. Virginia.  To determine if an individual is intellectually disabled, they must demonstrate subaverage adaptive skills that existed before age eighteen.  The Court has also recognized that IQ scores carry a ±5 margin of error and has …


The Impact Of An Interactive Open Education Textbook For An Undergraduate Introductory Chemistry Course For Nonmajors, Erin Avram Apr 2026

The Impact Of An Interactive Open Education Textbook For An Undergraduate Introductory Chemistry Course For Nonmajors, Erin Avram

Chemistry Faculty Publications

Reading informational text is a critical skill across most professions. Unfortunately, students are less likely to purchase the required course materials now compared to 2010. A free, interactive text was developed for an introductory chemistry course for non-STEM majors. This involved remixing existing texts and incorporating interactive activities to engage students during the learning process and provide opportunities for them to gauge their learning. Based on the results of a student survey, 82% of students reported that it was very important to them that the text was free and 80% of students who responded reported that they used the eText …


Modeling Bitcoin Dynamics Using Differential Equations, Boone M. Fleenor Apr 2026

Modeling Bitcoin Dynamics Using Differential Equations, Boone M. Fleenor

Departmental Honors & Graduate Capstone Projects

In this thesis, we develop and analyze two nonlinear systems of ordinary differential equations to model Bitcoin price dynamics. Analytical techniques are used to obtain exact or approximate solutions where possible. Then, numerical simulations using a fourth-order Runge–Kutta method are employed to explore system behavior beyond analytically tractable regimes. Finally, model outputs are compared to historical Bitcoin price data using normalized and resampled time series. These results suggest that deterministic models can provide meaningful insight into the structural behavior of Bitcoin markets, while highlighting the need for stochastic or time-dependent extensions for more realistic modeling.


Hybrid Bermudagrass Dormancy Management In A Cool-Season Climate, Clarissa H. Peterson Apr 2026

Hybrid Bermudagrass Dormancy Management In A Cool-Season Climate, Clarissa H. Peterson

Theses and Dissertations

Hybrid bermudagrass (Cynodon dactylon [L.] Pers. × C. transvaalensis Burtt Davy) (HBG) is a water efficient warm-season turfgrass increasingly adopted in cool-season and semi-arid regions due to climate change and the demand for reduced irrigation inputs. However, prolonged winter dormancy limits its visual quality (verdure) and seasonal performance. This thesis evaluated multiple management strategies to modify dormancy dynamics and improve off-season turf quality in a cool-season environment. Field experiments assessed the effects of growth covers, fertilizers, colorants, surfactants, organic acids, and overseeding with cool-season species on HBG dormancy over two seasons. Dormancy responses were quantified using normalized difference vegetation index …


Rooted In Service, Reaching For The Stars, Lucila Ojeda '26 Apr 2026

Rooted In Service, Reaching For The Stars, Lucila Ojeda '26

Senior Presentation of Learning

My biggest takeaway from Bonner is to not be afraid to ask for help. Coming from out of state, the transition from a familiar community to somewhere completely foreign was scary. The kindness shown to me by the people at Bonner is something I will never forget. Do it scared and take the leap of faith in reaching out and building your community. Bonner will help you as much as they can, and I hope my service has reflected the support I have been so fortunate to receive.


Artificial Intelligence-Assisted Neuropharmacology: Reshaping Drug Discovery And Translational Strategies For Neurological Diseases ​, Pri̇yanka Rathee, Suni̇thi̇ Lohan, Sari̇ta Khatkar, Neelam Mali̇k, Esra Akkol, Renu Sehrawat, Pooja Rathee, Anurag Khatkar Apr 2026

Artificial Intelligence-Assisted Neuropharmacology: Reshaping Drug Discovery And Translational Strategies For Neurological Diseases ​, Pri̇yanka Rathee, Suni̇thi̇ Lohan, Sari̇ta Khatkar, Neelam Mali̇k, Esra Akkol, Renu Sehrawat, Pooja Rathee, Anurag Khatkar

Turkish Journal of Medical Sciences

The rapid expansion of data-driven technologies, particularly machine learning (ML) and artificial intelligence (AI), has substantially influenced biomedical research and drug discovery. In neuropharmacology, the availability of large-scale genomic, proteomic, chemical, and clinical datasets has stimulated the adoption of AI-based approaches to address persistent challenges in neurological drug development, including high attrition rates and the scarcity of disease-modifying therapies. Unlike prior reviews that broadly discuss AI applications in drug discovery or neurology, this narrative review focuses specifically on neuropharmacology, with an emphasis on translational relevance, disease-oriented examples, and real-world constraints. We critically examine the application of AI and ML across …


Impact Of Two Sedation Protocols On Cardiac Electrophysiology During Spinal Anesthesia ​, Selvi̇naz Durantaş, Burak Nalbant, Fatma Kavak Akelma, Gökhan Erdem, Abdulkadi̇r But Apr 2026

Impact Of Two Sedation Protocols On Cardiac Electrophysiology During Spinal Anesthesia ​, Selvi̇naz Durantaş, Burak Nalbant, Fatma Kavak Akelma, Gökhan Erdem, Abdulkadi̇r But

Turkish Journal of Medical Sciences

Background/aim: Perioperative factors such as anesthetic drugs, central blocks, surgical stress, pain, and anxiety can affect cardiac electrophysiology and increase the risk of arrhythmias. Arrhythmia susceptibility can be assessed using ventricular markers such as the QT interval (QT), heart rate-corrected QT interval (QTc), QT dispersion (QTd), time between peak and end of T wave (Tp–e), cardiac electrophysiologic balance index (iCEB), and heart rate-corrected index of cardiac electrophysiologic balance (iCEBc), obtained from noninvasive electrocardiography (ECG) data. This study compared the effects of propofol and dexmedetomidine sedation on these parameters in patients undergoing total knee arthroplasty performed under spinal anesthesia.

Materials and …


Analysis Of Calr-Mutated Essential Thrombocythemia As A Distinct Disease Entity Compared With Jak2 V617f-Mutated And Triple-Negative Patients ​, Gökhan Sami̇ Aydin, Eli̇f Aksoy, İpek Yönal Hi̇ndi̇lerden, Aynur Dağlar Aday, Emi̇ne Gültürk, Meli̇ha Nalçaci, Fehmi̇ Hi̇ndi̇lerden Apr 2026

Analysis Of Calr-Mutated Essential Thrombocythemia As A Distinct Disease Entity Compared With Jak2 V617f-Mutated And Triple-Negative Patients ​, Gökhan Sami̇ Aydin, Eli̇f Aksoy, İpek Yönal Hi̇ndi̇lerden, Aynur Dağlar Aday, Emi̇ne Gültürk, Meli̇ha Nalçaci, Fehmi̇ Hi̇ndi̇lerden

Turkish Journal of Medical Sciences

Background/aim: Calreticulin (CALR) mutations in essential thrombocythemia (ET) are associated with younger age, higher platelet counts, and lower thrombosis rates. The present study analyzes the demographic, laboratory, and clinical features of the CALR mutation and its prognostic impact.

Materials and methods: The clinical impact of CALR mutations was assessed in 391 ET patients.

Results: CALR-mutation patients were more commonly male than JAK2 V617F-positive and triple-negative patients. Age at diagnosis was similar across all groups, although patients with type 2 CALR mutations were younger than those with nontype 1/nontype 2 mutations. Compared with JAK2 V617F-positive patients, CALR-mutation patients had lower leukocyte …