Digital Commons Network^™

Development Of Jetty Structure Design Procedures At The Schematic Design Stage With The Implementation Of Computational Design And Building Information Modelling To Improve Design Time Performance, Aidil Fitriansyah, Yusuf Latief

CSID Journal of Infrastructure Development

The construction sector faces persistent productivity challenges, significantly hindering the efficiency of design workflows. Computational Design (CD) and Building Information Modeling (BIM) offer potential solutions. CD enables the exploration of parametric design alternatives, while BIM enhances collaboration, visualization, and decision-making through comprehensive 3D models. This study aimed to investigate the processes and activities involved in the structural design of jetties during the schematic design phase using CD and BIM and to assess the impact of these activities on design time performance. A comprehensive analysis of secondary data was carried out, interviews were conducted with design experts, and quantitative analysis using …

The Role Of Stakeholder Involvement In Enhancing Safe Drinking Water Infrastructure: An Interpretative Structural Modeling Approach, Awlya Rahmanea, Ayomi Dita Rarasati

CSID Journal of Infrastructure Development

One of the primary goals listed in the Sustainable Development Goals (SDGs) is to “Achieve universal and equitable access to safe and affordable drinking water for all,” as stated in SDG 6.1. To obtain this goal, the Government of Indonesia has developed the 2020-2024 National Medium-Term Development Plan (RPJMN), which has set specific targets including achieving 100% access to decent drinking water, 15% access to safe drinking water, and establishing 10 million house connections. The Ministry of National Development Planning has established a goal of achieving 45% access to safe drinking water by 2030 as part of the SDGs. However, …

The Most Influential Factors On The Risk Cost Estimation Process Of Implementing Bim 5d In Quantity Take-Off For Green Retrofitting Of High-Rise Buildings, Febrianti Silviana Dewi, Yusuf Latief, Bernadette Detty Kussumardianadewi

CSID Journal of Infrastructure Development

Green retrofitting aims to guide buildings toward sustainable practices, reducing carbon emissions associated with building operations and construction. This study explores the application of Building Information Modeling (BIM) 5D Quantity Take-Off (QTO) to existing high-rise buildings, focusing on components that enhance the performance of environmentally friendly structures and project management. This research identifies the factors influencing the cost estimation process and examines the risks across various phases, activities, outputs, and utilization of BIM 5D in cost estimation. The study highlights the most influential factors in implementing green retrofitting for high-rise buildings using structured interviews, questionnaires, and expert validation. The analysis …

Hair Dye And Relaxer Use Among Cisgender Women In Embu And Nakuru Counties, Kenya: Associations With Perceived Risk Of Breast Cancer And Other Health Effects, Adana A. M. Llanos, Adiba Ashrafi, Teresa Olisa, Amber Rockson, Alexis Schaefer, Jasmine A. Mcdonald, Mary Beth Terry, Dede K. Teteh-Brooks, Dustin T. Duncan, Beatrice Irungu, Cecilia Kimani, Esther Matu

Health Sciences and Kinesiology Faculty Articles

Despite widespread use of hair products globally, little is known about the prevalence and patterns of use in populations outside the United States. As some hair products contain endocrine-disrupting chemicals (EDCs) and EDCs have been linked to breast cancer, which is increasing globally, in this study, we addressed key knowledge gaps about hair product use and practices, and perceptions of use among women in two counties in Kenya. Using community-engaged approaches in Embu and Nakuru, Kenya, we recruited women aged 15–50 years to complete a questionnaire that ascertained hair product use in the last 7–14 days, ever using hair dyes …

Frank Nellom V. Commissioner Of Social Security

2024 Decisions

USDC for the Eastern District of Pennsylvania

Comprehensive Analysis Of The Different Fields Of Law, Kaitlyn Lee

Honors Theses

Since American law developed in the early 1700s, lawyers have played a crucial role in society, advocating for justice and upholding the rule of law. Over the years the legal profession has evolved immensely and now offers many different fields for individuals to practice. People are often curious about the work that lawyers do and the education that is required to become an attorney. This thesis aims to satisfy the curiosity of those individuals by exploring many facets of the different areas of law. It will examine the unique and shared aspects of the various legal fields, detailing the specific …

Obesity Is Associated With Muscle Atrophy In Rotator Cuff Tear, Simone D Herzberg, Robert H Brophy, Matthew V Smith, Et Al.

2020-Current year OA Pubs

OBJECTIVE: The primary goal of this study is to evaluate the relationship between Body Mass Index (BMI) and muscle atrophy in individuals with rotator cuff tears.

METHODS: This study consists of patients with rotator cuff tears identified by MRI from two independent cohorts, the Rotator Cuff Outcomes Workgroup (ROW) and the Multicenter Orthopaedic Outcomes Network (MOON). Presence of atrophy (yes/no) and severity of atrophy (as an ordinal variable) were assessed on MRI by expert physicians. We used multivariable regression models to evaluate the relationship between BMI and muscle atrophy while adjusting for age and sex in each study, conducted sensitivity …

Loss Of Hormone Receptor Expression After Exposure To Fluid Shear Stress In Breast Cancer Cell Lines, Jonathan Cuccia, Braulio Andres Ortega Quesada, Ethan P. Littlefield, Alejandra M. Ham, Matthew E. Burow, Adam T. Melvin, Elizabeth C. Martin

School of Medicine Faculty Publications

Following metastatic spread, many hormone receptor positive (HR(+)) patients develop a more aggressive phenotype with an observed loss of the HRs estrogen receptor (ER) and progesterone receptor (PR). During metastasis, breast cancer cells are exposed to high magnitudes of fluid shear stress (FSS). Unfortunately, the role for FSS on the regulation of HR expression and function during metastasis is not fully understood. This study was designed to elucidate the impact of FSS on HR(+) breast cancer. Utilizing a microfluidic platform capable of exposing breast cancer cells to FSS that mimics in situ conditions, we demonstrate the impact of FSS exposure …

Laurel Gardens Llc V. Timothy Mckenna

2024 Decisions

USDC for the Eastern District of Pennsylvania

Rene Bautista-Rosales V. Attorney General United States Of America

2024 Decisions

Agency

In Re: Judeau Brown, Jr.

2024 Decisions

USDC for the District of Delaware

Terry Dor V. Td Bank

2024 Decisions

USDC for the District of New Jersey

Monitoring Water Meniscus Formation At Nanocontacts With Shear-Force Acousto Near-Field Microscopy, Xiaohua Wang, Rodolfo Fernandez, Theodore Brockman, Kacharat Supichayanggoon, Andres H. La Rosa

Physics Faculty Publications and Presentations

Shear-force acoustic near-field microscopy (SANM) is employed to monitor stochastic formation and post dynamic response of a water meniscus that bridges a tapered gold probe (undergoing lateral oscillations of a few nanometers amplitude at constant frequency) and a flat (gold or silicon oxide) substrate. As the probe further approaches the substrate, its amplitude decreases. Shear forces (of yet unknown precise origin) are typically invoked to explain the apparently pure damping effects affecting the probe's motion. Herein, SANM measurements underscore instead the role of near-field acoustic emission from the water meniscus as an elastic energy dissipation channel involved in shear interactions. …

Python Tooth–Inspired Fixation Device For Enhanced Rotator Cuff Repair, Iden Kurtaliaj, Ethan D. Hoppe, Yuxuan Huang, David Ju, Jacob A. Sandler, Donghwan Yoon, Lester J. Smith, Silvio Torres Betancur, Linda Effiong, Thomas Gardner, Liana Tedesco, Sohil Desai, Victor Birman, William N. Levine

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Rotator cuff repair surgeries fail frequently, with 20 to 94% of the 600,000 repairs performed annually in the United States resulting in retearing of the rotator cuff. The most common cause of failure is sutures tearing through tendons at grasping points. To address this issue, we drew inspiration from the specialized teeth of snakes of the Pythonoidea superfamily, which grasp soft tissues without tearing. To apply this nondamaging gripping approach to the surgical repair of tendon, we developed and optimized a python tooth–inspired device as an adjunct to current rotator cuff suture repair and found that it nearly doubled repair …

Mhealth-Based Just-In-Time Adaptive Intervention To Improve The Physical Activity Levels Of Individuals With Spinal Cord Injury: Protocol For A Randomized Controlled Trial, Rachel Carey, Ha Le, Donna Coffman, Inbal Nahum-Shani, Mohanraj Thirumalai, Cole Hagen, Laura Baehr, M. Schmidt-Read, Marlyn Lamboy, Stephanie A Kolakowsky-Hayner, Ralph Marino, Stephen Intille, Shivayogi Hiremath

Moss-Magee Rehabilitation Papers

BACKGROUND: The lack of regular physical activity (PA) in individuals with spinal cord injury (SCI) in the United States is an ongoing health crisis. Regular PA and exercise-based interventions have been linked with improved outcomes and healthier lifestyles among those with SCI. Providing people with an accurate estimate of their everyday PA level can promote PA. Furthermore, PA tracking can be combined with mobile health technology such as smartphones and smartwatches to provide a just-in-time adaptive intervention (JITAI) for individuals with SCI as they go about everyday life. A JITAI can prompt an individual to set a PA goal or …

Brief Amicus Curiae Of Professor Matthew Steilen In Support Of Petitioners, Tiktok Inc. V. Garland (D.C. Cir. 2024) (No. 24-1113), Matthew J. Steilen

Other Scholarship

No abstract provided.

Considerations For Quality Control Monitoring Of Machine Learning Models In Clinical Practice, Louis Faust, Patrick Wilson, Shusaku Asai, Sunyang Fu, Hongfang Liu, Xiaoyang Ruan, Curt Storlie

Faculty, Staff and Student Publications

Integrating machine learning (ML) models into clinical practice presents a challenge of maintaining their efficacy over time. While existing literature offers valuable strategies for detecting declining model performance, there is a need to document the broader challenges and solutions associated with the real-world development and integration of model monitoring solutions. This work details the development and use of a platform for monitoring the performance of a production-level ML model operating in Mayo Clinic. In this paper, we aimed to provide a series of considerations and guidelines necessary for integrating such a platform into a team's technical infrastructure and workflow. We …

Repair And Surface Functionalization Of Fiber Reinforced Polymer Composites By Cold Spray, Ibnaj Anamika Anni

Theses and Dissertations

Fiber-reinforced polymer composites are widely used in industries and applications such as energy, automotive, defense, and aerospace. This study investigates the application of polymer cold spray, an emerging additive manufacturing process, for coating and repair of fiber-reinforced polymer (FRP) composites. The research starts with feasibility studies focused on the cold spray deposition of thermoplastic nylon-6 particles on woven glass fiber-reinforced composites (GFRP). A parametric study determines critical process parameters window, ensuring successful deposition and bonding without compromising the macroscale mechanical behavior. These findings indicate that the cold spray process does not adversely affect the fiber integrity or surface quality of …

Chemotherapy Drug Release From Hollow Core Polyethyleneimine Nanoparticles, Brian Boyle

Theses and Dissertations

Novel anticancer delivery vehicles are arising from engineered nanostructured materials. This work involved the synthesis, characterization, and release of novel hollow core polymeric nanoparticles (HCPNPs) for controlled drug delivery. Polyethyleneimine (PEI) was bound to AuNPs, forming polymer-shell nanoparticles with dissolution of the gold core via iodine forming HCPNPs with drug intercalated DNA bound to the surface. A high density (85 molecules/particle) of DNA intercalated with daunorubicin was conjugated. Particles were spherical with an average diameter of 105.7 ± 17.3 nm and zeta potential of 20.4 ± 3.54 mV. We hypothesize the DNA backbone electrostatically condensed to the primary amines on …

Kibra Anchoring The Action Of Pkmζ Maintains The Persistence Of Memory, Panayiotis Tsokas, Changchi Hsieh, Rafael E Flores-Obando, Matteo Bernabo, Andrew Tcherepanov, A Iván Hernández, Christian Thomas, Peter J Bergold, James E Cottrell, Joachim Kremerskothen, Harel Z Shouval, Karim Nader, André A Fenton, Todd C Sacktor

Faculty, Staff and Student Publications

How can short-lived molecules selectively maintain the potentiation of activated synapses to sustain long-term memory? Here, we find kidney and brain expressed adaptor protein (KIBRA), a postsynaptic scaffolding protein genetically linked to human memory performance, complexes with protein kinase Mzeta (PKMζ), anchoring the kinase's potentiating action to maintain late-phase long-term potentiation (late-LTP) at activated synapses. Two structurally distinct antagonists of KIBRA-PKMζ dimerization disrupt established late-LTP and long-term spatial memory, yet neither measurably affects basal synaptic transmission. Neither antagonist affects PKMζ-independent LTP or memory that are maintained by compensating PKCs in ζ-knockout mice; thus, both agents require PKMζ for their effect. …

May 2024 Berkeley Pit Migratory Waterfowl Protection Monthly Report, Mark Thompson, Loren Burmeister

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Python Tooth-Inspired Fixation Device For Enhanced Rotator Cuff Repair, Iden Kurtaliaj, Ethan D Hoppe, Yuxuan Huang, David Ju, Jacob A Sandler, Donghwan Yoon, Guy M Genin

2020-Current year OA Pubs

Rotator cuff repair surgeries fail frequently, with 20 to 94% of the 600,000 repairs performed annually in the United States resulting in retearing of the rotator cuff. The most common cause of failure is sutures tearing through tendons at grasping points. To address this issue, we drew inspiration from the specialized teeth of snakes of the Pythonoidea superfamily, which grasp soft tissues without tearing. To apply this nondamaging gripping approach to the surgical repair of tendon, we developed and optimized a python tooth-inspired device as an adjunct to current rotator cuff suture repair and found that it nearly doubled repair …

Bayesian Analysis Of Hospital Service Quality: Pre- And Post-Covid, Ling Hu

USF Tampa Graduate Theses and Dissertations

The hospital sector is the largest revenue-generating industry in the United States, with a revenue of $1.4 trillion in 2022, accounting for 5.8% of the U.S. GDP. Its service quality profoundly impacts societal welfare, especially given the aging population reached 55.8 million in 2020 and is expected to reach 82 million by 2050. Therefore, multiple policies aim to incentivize sustained healthcare service quality improvements. As an integral component of the Hospital Value-Based Purchasing (HVBP) Program, the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey, administrated by the Centers for Medicare and Medicaid Services (CMS), serves as a cornerstone …

The Influence Of Recycled Water On Microbial Source Tracking Techniques That Aim To Identify Untreated Sewage In Surface Waters, Aldo E. Lobos

USF Tampa Graduate Theses and Dissertations

Fecal pollution in recreational waters can introduce pathogens that cause increased human health risk, where exposure can occur during recreational activities such as swimming, diving, surfing, and fishing. Furthermore, human fecal pollution (i.e., sewage) can introduce nutrients and other harmful chemicals that may negatively affect the environment and aquatic species. Generally, sewage is considered the highest risk to human health compared to animal fecal pollution because it typically contains a high diversity of pathogens (including human specific viruses), antibiotic resistant bacteria and genes associated with antibiotic resistance. However, pathogens are difficult to detect due to their low concentrations in the …

The Discovery Of First Ret Protac With In Vivo Activity, Yafeng Wang

USF Tampa Graduate Theses and Dissertations

This report mainly discusses the development of RET Proteolysis targeting chimera PROTAC molecules based on Selpercatinib (LOXO-292) and Sulfono-γ-AApeptide PROTAC. A PROTAC molecule is a bifunctional molecule composed of two active domains and a linker. It works by inducing selective protein intracellular degradation. This technology was first discussed by Kathleen Sakamoto, Ray Deshaies and Craig Crews in 2001. Using various E3 Ligase, such as CRBN, pVHL, beta-TrCP1, Mdm2, DCAF15, DCAF16, RNF114, and c-IAP1, the PROTAC technology has been applied to several novel drug development,. Yale University licensed the PROTAC technology to Arvinas in 2013–14. For my research, Chapter one summarizes …

The Conflict Between The United States And Iran And Its Effect On Iraq, Sarah Alsalih

Dissertations and Theses

This thesis examines the dynamic interplay between the United States and Iran and its repercussions on Iraq in the post-9/11 era. Against a backdrop of historical adversities, the research delves into the evolving relationship between the U.S. and Iran, elucidating its multifaceted dimensions and the consequential effects on Iraq. The central inquiry driving this investigation is: "Against the adversarial historical backdrop of U.S.-Iran relations, how has the relation between the two countries changed and impacted Iraq throughout the post 9/11 era?"

Drawing upon a comprehensive analysis through the lens of diplomatic interactions, military interventions, and regional dynamics, this study seeks …

Table Of Contents, Nicholas Conti

The Journal of Business, Entrepreneurship & the Law

No abstract provided.

Rights In Conflict: Examining Investment Treaty Arbitration And Intellectual Property Rights In The Wake Of Russia’S Invasion Of Ukraine, Grace Klutke

The Journal of Business, Entrepreneurship & the Law

This article examines how the armed Ukraine-Russia conflict opened a doorway for a wave of international arbitration via corporate actions against Russia for violating BIT obligations. To provide context for the suggested BIT arbitration against Russia, this article begins with a brief discussion of the historical background of this conflict and investor-state treaty arbitration. This article next pivots to analyze the applicability of investor-state treaty arbitration to compensate lost IP investments in three parts. Part I considers how investor-state treaty arbitration function with ongoing armed conflict and which investors may initiate investor-state treaty claims. Next, Part II reports on the …

Box Office Knockout: The Future Of Theaters In An Industry Racing To Outpace Them, Jakob Stokes

The Journal of Business, Entrepreneurship & the Law

This article examines the historical and contemporary impacts of antitrust measures in the film industry, focusing on the significant Paramount Decrees which initially aimed to dismantle the monopolistic practices of the "Big Five" and "Little Three" studios. It discusses the evolution of these decrees and their relevance in today's landscape dominated by a new set of major players. The article further explores the current debate surrounding the shortening of the cinematic window of exclusivity, delving into the implications of various premium video on demand services, such as Disney Premier Access, and the arguments both for and against shortened windows. It …

The Legal Liabilities Of Twitch, Amazon’S Livestreaming Subsidiary, Jean Fang

The Journal of Business, Entrepreneurship & the Law

Amazon’s Twitch is the leader of the video game streaming market, controlling 76% of this market in the Americas and Europe. The video gaming market is rapidly expanding, exceeding its entertainment counterparts, including music and film, by wide margins in profits; experts valued the global gaming market at $229.39 billion in 2022 and expect it to grow to $401.32 billion by 2027. Amazon paid $1 billion to acquire Twitch in 2014 in a business move to capture the views of the gaming audience; on Twitch, popular streamers broadcast themselves playing video games to thousands of devoted fans. Based on recent …