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Articles 4081 - 4110 of 1190335
Full-Text Articles in Entire DC Network
In Re: Alecto Healthcare Services Llc
In Re: Alecto Healthcare Services Llc
2026 Decisions
USDC for the District of Delaware
Notch Signaling Regulates The Secretion Of Pro-Metastatic Factors In Extracellular Vesicles In Liposarcoma, Menchus Quan, Yi-Kai Liu, Ying Zhao, Madeline Kay, Kai Sun, Timothy P Gavin, Raphael E Pollock, W Andy Tao, Shihuan Kuang
Notch Signaling Regulates The Secretion Of Pro-Metastatic Factors In Extracellular Vesicles In Liposarcoma, Menchus Quan, Yi-Kai Liu, Ying Zhao, Madeline Kay, Kai Sun, Timothy P Gavin, Raphael E Pollock, W Andy Tao, Shihuan Kuang
The Brown Foundation: Institute of Molecular Medicine
Notch signaling is an emerging regulator of liposarcoma (LPS), but its role in mediating communication with the tumor microenvironment (TME) is unclear. Here, we investigate how Notch activation (NICD overexpression) alters the proteomes of LPS-derived extracellular vesicles (EVs). We used quantitative mass spectrometry to profile the EV proteome in multiple contexts: cultured LPS cells, LPS tumor, circulating EVs of LPS-bearing mice, and human LPS samples. We found that Notch signaling increases the secretion of EV proteins that favor tumor progression and metastasis but suppresses immune responses in murine LPS cells. Overlapping murine and human LPS data identifies 18 proteins that …
Timelines Over Tokens: Summarization, Prompting, And Explainable Fine-Tuning For User-Level Suicide Risk Detection, Aditya Tekale
Timelines Over Tokens: Summarization, Prompting, And Explainable Fine-Tuning For User-Level Suicide Risk Detection, Aditya Tekale
Master's Theses
This research presents a two-stage pipeline for user-level suicide risk detection from Reddit: first, inference-only prompting with summarization; second, fine-tuned encoder classification with explainability and expert validation. The data are user-level: each of the 500 C-SSRS Reddit items is one user’s chronologically concatenated posts and comments (a user timeline), annotated by psychiatrists. Stage one: six prompting strategies zero-shot, few-shot, chain-of-thought, tree-of-thought, least-to-most, and self-consistency are evaluated across six LLMs on multi-class and binary formulations; simple zero-shot achieves the highest balanced accuracy (0.53 multi-class). Error analysis shows longer inputs associate with misclassification (p = 0.002); domain-specific summarization (timelines >2,000 tokens) reduces …
Mechanisms Of Advanced And Energy Efficient Wastewater Treatment Technologies, Derek Belka
Mechanisms Of Advanced And Energy Efficient Wastewater Treatment Technologies, Derek Belka
Civil Engineering ETDs
This dissertation combines meta-omics, microbial ecology, and hydrodynamic analysis to explore mechanisms of enhanced biological phosphorus removal (EBPR) and aerobic granular sludge (AGS) in municipal wastewater treatment. Metagenomic and functional gene profiling of a laboratory sequencing batch reactor fed with amino acids and proteins, and with a low abundance of known polyphosphate-accumulating organisms (PAOs), revealed abundant Herpetosiphonaceae and Dermatophilaceae families possessed key PAO metabolic traits, including phosphate scavenging, anaerobic carbon pathways, and ppk2 gene variants aligned with established PAOs. These findings suggest amino acid-driven EBPR can occur via previously unrecognized taxa, challenging current engineering assumptions and highlighting the need for …
Inoculation Interventions, Prebunking, And Media Literacy Education Are Not The Same, Author Information Removed
Inoculation Interventions, Prebunking, And Media Literacy Education Are Not The Same, Author Information Removed
JMLE Submissions Open for Review
Inoculation theory-based interventions, prebunking, and media literacy education are often discussed together because all three can help people resist harmful information. Their overlap, however, does not make them interchangeable. This essay argues that clearer distinctions are needed, especially between inoculation and prebunking. Inoculation theory centers on threat-motivated resistance to influence, whereas prebunking is more accurately understood as refutational preemption. Media literacy education is a broader educational context in which either approach may be used. I focus in particular on the difference between forewarning and threat, arguing that forewarning may reasonably support inferences about threat in some contexts but should not …
Beyond Technical Proficiency: A Multidimensional Analysis Of Digital Citizenship And Civic Engagement Among South Korean College Students, Author Information Removed
Beyond Technical Proficiency: A Multidimensional Analysis Of Digital Citizenship And Civic Engagement Among South Korean College Students, Author Information Removed
JMLE Submissions Open for Review
This study investigates how specific sub-dimensions of digital citizenship predict civic engagement among South Korean college students (N=497). Using hierarchical multiple regression with gender and SNS usage time as covariates, this research analyzes four subdimensions of digital citizenship—digital literacy, participation, critical perspective, and ethics—alongside three layers of civic engagement: sense of community, social responsibility, and sociopolitical participation. Hierarchical regression analyses revealed that while digital literacy functions as a baseline competency, digital participation and digital ethics serve as the most consistent predictors of civic engagement. Notably, digital participation was strongly associated with sociopolitical action, suggesting a meaningful spillover effect, while a …
Genocide By Algorithm In Gaza: Artificial Intelligence, Countervailing Responsibility, And The Corruption Of Public Discourse, Branislav Radeljić
Genocide By Algorithm In Gaza: Artificial Intelligence, Countervailing Responsibility, And The Corruption Of Public Discourse, Branislav Radeljić
Genocide Studies and Prevention: An International Journal
The accelerating militarization of artificial intelligence (AI) has transformed the ethics, politics, and governance of warfare. This article interrogates how AI-driven targeting systems function as epistemic infrastructures that classify, legitimize, and execute violence, using Israel’s conduct in Gaza as a paradigmatic case. Building on interdisciplinary debates in security studies, critical technology studies, and international law, the paper advances the concept of "genocide by algorithm"—a mode of technologically mediated extermination in which opaque computational systems automate and rationalize mass violence. The study argues that these systems collapse distinctions between military and civilian targets, and between intentional and accidental harm, thereby eroding …
Genocidal Occupation And The Occupier’S Dilemma: From Lemkin’S Axis Rule To 21st Century Palestine, Martin Shaw
Genocidal Occupation And The Occupier’S Dilemma: From Lemkin’S Axis Rule To 21st Century Palestine, Martin Shaw
Genocide Studies and Prevention: An International Journal
Following Israel’s campaign in Gaza after October 7, 2023, which was widely recognized as a genocide, the “ceasefire” of late 2025 introduced the prospect of a new occupation of the territory by the USA and Israel, leading to its redevelopment by them rather than the restoration of the pre-2023 Palestinian society. Together with the parallel accentuation of Palestinian dispossession under Israeli occupation in the West Bank, this development calls for a theorization of the relationship between occupation and genocide. Yet, although the concept of genocide was introduced by Raphael Lemkin in his analysis of the German occupations of European countries, …
U.S. Public Opinion During The Rwandan Genocide And The Power Of Executive Detachment, Carly Schmitt, Matthew L. Bergbower
U.S. Public Opinion During The Rwandan Genocide And The Power Of Executive Detachment, Carly Schmitt, Matthew L. Bergbower
Genocide Studies and Prevention: An International Journal
We examine U.S. public opinion during the Rwandan genocide in the spring and early summer of 1994. Drawing on more than a dozen public opinion polls fielded during this period, we analyze Americans’ levels of knowledge about the violence in Rwanda, their views on United Nations involvement, support for U.S. military intervention, and evaluations of President Bill Clinton’s handling of the crisis. Longstanding theory recognizes public opinion as an important variable in explaining foreign policy choices during international crises. In the case of U.S. policy toward the Rwandan genocide, our analysis reveals widespread public unfamiliarity with a distant African conflict …
Luis Lora Fontalvo V. Director Federal Bureau Of Prisons
Luis Lora Fontalvo V. Director Federal Bureau Of Prisons
2026 Decisions
USDC for the Western District of Pennsylvania
Barbara Banks V. Tunic Group Llc
Order Granting Derivative Standing
Order Granting Derivative Standing
Catholic Dioceses in Bankruptcy
No abstract provided.
Mapping And Modeling Threat-Evoked Brain States After Early Life Adversity, Taylor W. Uselman
Mapping And Modeling Threat-Evoked Brain States After Early Life Adversity, Taylor W. Uselman
Biomedical Sciences ETDs
Early life adversity (ELA) increases lifelong neuropsychiatric vulnerability. Yet how ELA reorganizes brain-wide activity and circuit coordination across later experience remains unclear. This dissertation tests the hypothesis that ELA alters adult brain-wide activity and responses to threat through disrupted coordination among neural systems that regulate emotional experience, including prefrontal-limbic and monoaminergic systems. Longitudinal manganese-enhanced MRI of adult mice exposed to standard or fragmented early care, combined with computational processing and statistical modeling, quantified brain states before, during, and long after innate predator threat. These studies established that acute threat evokes large-scale, distributed brain activity that evolves over time. ELA potentiates …
Co-Constructing The Common Ground: Responses In American Sign Language Conversation, Deborah Wager
Co-Constructing The Common Ground: Responses In American Sign Language Conversation, Deborah Wager
Linguistics ETDs
Common ground between two people consists of the things they both know, that they know they both know. This body of knowledge grows in conversation, through both verbal and nonverbal responses. Responses communicate whether what has been said was accepted into the common ground, and return responses acknowledge this acceptance in turn (H. H. Clark, 1996). In addition to the semantic content of utterances, stance is communicated through a variety of means, and alignment with that stance is also communicated through responses.
This study explores ways in which responses are used in American Sign Language (ASL) conversation to co-construct the …
From Chromosomes To Precision Therapy: Clinical Cytogenetics And Cytogenomics In The Era Of Genomic Medicine, Jinglan Liu
From Chromosomes To Precision Therapy: Clinical Cytogenetics And Cytogenomics In The Era Of Genomic Medicine, Jinglan Liu
Department of Pathology, Anatomy, and Cell Biology Faculty Papers
No abstract provided.
Technology Platform (Peer Plus) Supporting The Work Of Peer Recovery Coaches And The Communication Needs Of Individuals In Recovery From Substance Use Disorder: Protocol For An R21 Development And Usability Trial., Amanda Coupe, Jessica Pater, Rachel Pfafman, Victor P Cornet, Elisabeth Andrews, Mindy Flanagan, Dana Albright, Abhinay Balasani, Christopher Becker, Brian Parise, Erik Hess, Tammy Toscos
Technology Platform (Peer Plus) Supporting The Work Of Peer Recovery Coaches And The Communication Needs Of Individuals In Recovery From Substance Use Disorder: Protocol For An R21 Development And Usability Trial., Amanda Coupe, Jessica Pater, Rachel Pfafman, Victor P Cornet, Elisabeth Andrews, Mindy Flanagan, Dana Albright, Abhinay Balasani, Christopher Becker, Brian Parise, Erik Hess, Tammy Toscos
Health Services and Informatics Research
BACKGROUND: Substance use disorder (SUD) represents a significant public health concern in the United States. SUD recovery is complex and individualized, and support provided by peer recovery coaches (PRCs) can improve outcomes. The PRC-client relationship requires bidirectional mediated communication that is often informal but should be trackable, efficient, and aligned with health care privacy and security regulations. Current workflows and available apps do not meet these needs, illustrating the opportunity for client-centered technology tools. We have developed Peer PLUS (People Leveraging Urgent Support; Parkview Health System, Inc), a HIPAA (Health Insurance Portability and Accountability Act)-compliant mobile app and client management …
Essays On Environmental, Social, And Governance Strategy, Samuel Kim
Essays On Environmental, Social, And Governance Strategy, Samuel Kim
Olin Business School Graduate Student Theses and Dissertations
The strategic consequences of an organization's Environmental, Social, and Governance (ESG) efforts are driven largely by the specific information stakeholders observe and evaluate. As firms project a growing volume of public claims and observable social outcomes, stakeholders must navigate a complex informational environment to decide how much weight to assign to what organizations say, what they do, and whether their words are consistent with their actions. Clarifying how stakeholders interpret these varied signals is therefore vital to understanding the strategic implications of ESG efforts. To that end, this dissertation asks: how are different pieces of organizational information related to stakeholder …
Acute Inflammation At Host-Biomaterial Interfaces: Development Of Neutrophil-Mediating Therapeutics And Biomaterials, Evan Norman Main
Acute Inflammation At Host-Biomaterial Interfaces: Development Of Neutrophil-Mediating Therapeutics And Biomaterials, Evan Norman Main
Electronic Theses and Dissertations Archive
Neutrophils, key mediators of the acute host response to implanted biomaterials, engage in inflammatory signaling, form neutrophil extracellular traps (NETs), and generate reactive oxygen species (ROS). Upon contact with foreign materials, neutrophils release pro-inflammatory cytokines and chemokines that recruit additional immune cells and promote pro-inflammatory phenotypes in neutrophils and macrophages. Neutrophils may also undergo NETosis, a process involving the release of chromatin-based NETs to sequester and degrade foreign material. In excess, NET formation can impede tissue integration by physically isolating biomaterial surfaces while amplifying inflammation through the release of degradative enzymes and inflammatory mediators. Neutrophil-derived ROS contribute to oxidative stress …
Constructing Heroes In The Classroom: A Rhetorical Analysis Of Abeka’S Evangelical K-12 Curriculum, Jeff S. Miller
Constructing Heroes In The Classroom: A Rhetorical Analysis Of Abeka’S Evangelical K-12 Curriculum, Jeff S. Miller
Electronic Theses and Dissertations Archive
This study critically analyzes the rhetoric of four textbooks published by Abeka, Inc., a popular producer of curriculum for both American evangelical Christian K-12 school and homeschoolers through the lens of heroic rhetoric and anthropologist Ernest Becker’s hero systems, examining institutions’ and communities’ rhetorical construction of hero systems that provide or claim to provide relief to members’ mortality anxiety. Hero systems for each of the four textbooks are identified and examined for the ways that they function to build and maintain power hierarchies. Additionally three significant thematic threads of what constitutes heroism are identified in the textbook: biblicism, unidirectional influence, …
West Coast Workshop To Southwest Institute, Hannah Marie Cerne
West Coast Workshop To Southwest Institute, Hannah Marie Cerne
Art & Art History ETDs
This thesis considers Tamarind Institute in Albuquerque, New Mexico (originally established as Tamarind Lithography Workshop in Los Angeles, CA), and its contributions to collaborative printmaking. Originally founded in 1960 by June Wayne with Clinton Adams and Garo Antreasian, Tamarind Lithography Workshop (the precursor to Tamarind Institute) revitalized lithography through structured collaboration between artists and master printers, alongside rigorous training programs. This thesis provides an institutional history of the workshop during its relocation to the University of New Mexico, highlighting its transformation into a university-based institute that integrated education and professional production. Using social and labor-based methodologies, this study analyzes how …
Multi-Robot Cooperative System For Complex Aerospace Manipulation Tasks: Theory And Application, Longsen Gao
Multi-Robot Cooperative System For Complex Aerospace Manipulation Tasks: Theory And Application, Longsen Gao
Electrical and Computer Engineering ETDs
Multi-robot systems can extend manipulation capabilities beyond the limits of a single robot, particularly for tasks involving large, flexible, delicate, or free-floating payloads. Reliable cooperative manipulation, however, remains difficult when payload dynamics, contact geometry, compliance properties, deformation-induced forces, and external disturbances are only partially known, and when safety constraints must be enforced during physical interaction. This dissertation develops a two-layer control framework for resilient multi-robot manipulation under uncertainty, with emphasis on space servicing, satellite stabilization, aerial transportation, and cooperative manipulation of free-floating structures.
Unbroken Sovereignty: Land, Water, Education, And Nakoda And Oc̣Eti Ṡaḳowiŋ Tribes Of The Fort Peck Indian Reservation, 1850–1935, Richard Joseph Maska
Unbroken Sovereignty: Land, Water, Education, And Nakoda And Oc̣Eti Ṡaḳowiŋ Tribes Of The Fort Peck Indian Reservation, 1850–1935, Richard Joseph Maska
History ETDs
This dissertation explores the intersection of sovereignty and development among the Nakoda (Assiniboine) and Oc̣eti Ṡaḳowiŋ (Sioux) Tribes of the Fort Peck Indian Reservation during the late nineteenth and early twentieth centuries. Methodologically, it draws on a critical reading of archival sources in conjunction with community input. It traces the emergence of reservation policy, government sponsored education, the imposition of allotment policy and private landownership, and the impact of state-sponsored irrigation and other development projects. I argue that the Tribes forged webs of affiliation and kinship to both assert their nationhood and navigate their involvement in such projects. These expressions …
Exploring The Nature And Role Of Local Cation Ordering In Disordered Rock Salt Cathodes For Li- And Na-Ion Batteries, You Wang
Chemistry and Chemical Biology ETDs
Cation-disordered rock-salt (DRX) cathodes provide a highly tunable platform for next-generation Li- and Na-ion batteries, but their electrochemical behavior is strongly influenced by local structural features hidden in average crystal structures. This dissertation systematically investigates local cation ordering in Li- and Na-based DRX cathodes to understand its effects on Li+/Na+ transport, redox activity, structural evolution, and electrochemical performance. In Li-based systems, Raman spectroscopy and electrochemical analysis reveal that local layered cation ordering in Mn- and Fe-based DRX cathodes is closely correlated with electrochemical behavior. Over-stoichiometric Li-based DRX oxyfluorides further demonstrate that excess Li can regulate local cation ordering, improve Li+ …
Algorithmic Sculpting Of Complex Fused Silica Surfaces For Nondestructive, Mode-Matched Cavity Quantum Electrodynamics: Adaptive Co2 Milling And Simulation-Guided Ultrafast Inscription, From Fiber Fabry-Perot Cavities To Monolithic Architectures, Meagan E. Parker
Optical Science and Engineering ETDs
Quantum sensors achieve exceptional measurement sensitivity through coherent, well-isolated quantum systems, but practical deployment is hindered by destructive readouts that require repeated state preparation and create long system dead times. Optical cavities enable continuous, nondestructive measurements with minimal back-action, yet integrating high-finesse cavities into scalable quantum devices remains limited by existing fabrication methods. To overcome these constraints, an adaptive CO₂ laser-milling platform was developed. Guided by glass thermodynamics and melt dynamics, this closed-loop system uses in-situ phase-shifting interferometry to sculpt complex fused-silica surfaces with sub-nanometer root-mean-square roughness. The platform was validated by fabricating extended-length fiber Fabry–Pérot cavities and monolithic micro-cavity …
Extending The Discovery Space Of Tess: Probing Underexplored Exoplanet Populations, Mallory L. Harris
Extending The Discovery Space Of Tess: Probing Underexplored Exoplanet Populations, Mallory L. Harris
Physics & Astronomy ETDs
This dissertation investigates how cold exoplanets can be identified despite the strong observational bias of exoplanet surveys toward short-period systems. Planets at wider orbital separations remain comparatively poorly constrained, limiting tests of planetary-system formation and the prevalence of outer architectures beyond compact systems. To address this gap, I use two complementary approaches. First, I develop a transit-search pipeline for TESS Full-Frame Images that identifies both isolated and repeated transit-like signals around nearby M dwarfs and characterizes the dominant false-positive classes that limit sensitivity in this regime. I then present TOI-904 c, the coldest planet discovered by TESS around an M …
Exploring The Role Of A Mushy, Crustal Compliant Region In Volcano Deformation, Grant A. Block
Exploring The Role Of A Mushy, Crustal Compliant Region In Volcano Deformation, Grant A. Block
Physics & Astronomy ETDs
Volcanoes are both creative and destructive forces that have shaped and continue to shape our world from early geologic time to the present day. Continued study of volcanic processes not only better prepares us for monitoring volcanic hazards but also allows us to better understand processes fundamental to Earth as we know it, such as the generation of the atmosphere and accretion of the continents. This dissertation focuses on an integral part of volcanic processes: the trans-crustal magmatic transport system. Specifically, we investigate regions of these transport systems where magma pools in melt-rich lenses within broader regions of low melt-fraction, …
New Distance Distributions Of Asymptotic Giant Branch Stars And Their Role In Tracing Galactic Structure, Rajorshi Bhattacharya
New Distance Distributions Of Asymptotic Giant Branch Stars And Their Role In Tracing Galactic Structure, Rajorshi Bhattacharya
Physics & Astronomy ETDs
Asymptotic giant branch (AGB) stars are among the final evolutionary stages of low- and intermediate-mass stars and among the most luminous cool stellar populations in the Milky Way (MW). Their strong infrared emission allows them to be observed through regions of high interstellar extinction, making them useful tracers of the inner MW. However, their use is limited by unreliable distances because many are dust-obscured and variable, while geometric parallaxes are often unavailable or uncertain. This thesis develops statistical distance-estimation methods for large samples of oxygen-rich AGB stars. The resulting distances broadly agree with literature estimates, supporting their statistical reliability for …
Gradients Of Abandonment, William Tatman
Gradients Of Abandonment, William Tatman
Geography ETDs
As urban-rural disparities drive depopulation in rural areas worldwide, local strategies emerge as pathways for resilience. Research on Ojika, a Japanese island that has lost 75% of its population since the 1960s, reveals an Abandonment Gradient: a nuanced pattern of disuse adapted to modern polycrises. Extending the concept of "lying fallow" to homes and infrastructure, this thesis focuses on abandonment practices that reflect complex realities of labor, capital, and climate uncertainty. Rather than viewing depopulating communities as passive victims of out-migration, this paper argues they are critical sites for generating crisis response. Communally crafted attitudes toward unused space and more-than-human …
Who Bears The Burden: Tax Incidence And Water Governance In The Middle Rio Grande Conservancy District (Mrgcd) Within Bernalillo County, Michael W. Wilson
Who Bears The Burden: Tax Incidence And Water Governance In The Middle Rio Grande Conservancy District (Mrgcd) Within Bernalillo County, Michael W. Wilson
Economics ETDs
This study examines how property-value-based assessments within a large western irrigation and flood-control district distribute fiscal burdens across property owners. The empirical analysis is restricted to Bernalillo County within the Middle Rio Grande Conservancy District (MRGCD), using parcel-level administrative data from fiscal year 2025 merged with 2021 irrigation service records and geospatial information. The analysis classifies 34,397 parcels by irrigation status, agricultural valuation enrollment, and primary use to evaluate whether non-irrigating residential and commercial parcels, including renter-occupied properties that lack direct irrigation access, bear a disproportionate share of financial responsibility for a district whose first listed priority under their primary …