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Articles 28261 - 28290 of 1194635
Full-Text Articles in Entire DC Network
Course Schedule 2025-2026, William & Mary Law School
Course Schedule 2025-2026, William & Mary Law School
Course Information
No abstract provided.
Investigating Machine Learning Algorithms To Classify Label-Free Images Of Pancreatic Neuroendocrine Neoplasms, Noelle Daigle, Shuyuan Guan, Suzann Duan, Thomas G Knapp, Eung-Joo Lee, Ali Azhdarinia, Sukhen C Ghosh, Solmaz Aghaamiri, Servando Hernandez Vargas, Naruhiko Ikoma, Jeannelyn Estrella, Martin J Schnermann, Tobias Else, Michelle Kang Kim, Juanita L Merchant, Travis W Sawyer
Investigating Machine Learning Algorithms To Classify Label-Free Images Of Pancreatic Neuroendocrine Neoplasms, Noelle Daigle, Shuyuan Guan, Suzann Duan, Thomas G Knapp, Eung-Joo Lee, Ali Azhdarinia, Sukhen C Ghosh, Solmaz Aghaamiri, Servando Hernandez Vargas, Naruhiko Ikoma, Jeannelyn Estrella, Martin J Schnermann, Tobias Else, Michelle Kang Kim, Juanita L Merchant, Travis W Sawyer
The Brown Foundation: Institute of Molecular Medicine
Significance: Pancreatic neuroendocrine neoplasms (PNENs) are an uncommon cancer whose incidence rate has increased dramatically in recent years. Surgery is the only potentially curative treatment, which relies on both preoperative tumor localization and postoperative margin definition using histopathological examination for decision making. If pathology could be automated, valuable time and resources could be saved.
Aim: In this study, we investigate the ability of machine learning (ML) with handcrafted features, as well as deep learning, to classify label-free microscopy images of PNENs as a first step toward automated pathology of such tumors.
Approach: Patient samples of two different preparation types were …
Credible Theological Encroachment À La Clemente De Jesús Munguía, Juan Garcia Torres
Credible Theological Encroachment À La Clemente De Jesús Munguía, Juan Garcia Torres
Faith and Philosophy: Journal of the Society of Christian Philosophers
No abstract provided.
Matthew Benton, Knowledge And God, Charity Anderson
Matthew Benton, Knowledge And God, Charity Anderson
Faith and Philosophy: Journal of the Society of Christian Philosophers
No abstract provided.
Islams And Modernity In Cyprus And Turkey: A Comparative Perspective, Michael Todd Smith
Islams And Modernity In Cyprus And Turkey: A Comparative Perspective, Michael Todd Smith
School of Political Science, Public Affairs, Legal and Security Studies Faculty Publications
This article critically analyzes Aziz Al-Azmeh’s concept of Islams, while arguing for a contextbased analysis of the meeting between religious identity and modernity. It provides a loose framework for analyzing encounters between Islams and modernity in the cases of Cyprus and Turkey. Despite their close cultural and political connections at the rise of modernity, these two cases diverge, showcasing a high degree of public and private secularism in Cyprus and a contested public secularism and significant private religious identification in Turkey.
Arms Up Or Down? The Effect Of International Organization Membership On Military Expenditures, Maria Christina Kardash
Arms Up Or Down? The Effect Of International Organization Membership On Military Expenditures, Maria Christina Kardash
Student Publications
In this paper, I investigate the relationship between the total number of international organizations a state is involved in and its military expenditures as a percentage of GDP. Utilizing both qualitative and quantitative analysis, I find support for my hypothesis that the more international organizations a state is a member of, the less a state will expend on its military. Qualitatively, I focus on the three main theories of international relations (realism, liberalism, and constructivism) to construct a theoretical foundation for my paper. Under realism, I focus on free riding behavior, under liberalism, I center on non-military priorities, and under …
Examining The City Of Philadelphia’S Proposition Bill #250768 “Stop Trashing Our Air Act” By Addressing Waste Management And Environmental Justice Challenges In Chester City, Pennsylvania And The Philadelphia Region, Dylan Wascavage
Student Publications
This paper offers a policy analysis of the City of Philadelphia’s "Stop Trashing Our Air Act" by summarizing the reasoning for the bill's call to action, its legislative background, identifying key players and their strategies, and how these strategies reflect philosophies of environmental governance and the policy cycle. It seeks to inform local community members and policymakers of the implications of this bill, to highlight the lack of state and federal intervention on this issue, and to address the environmental justice and pollution concerns of the Covanta waste incinerator in Chester City and its neighboring communities. It also aims to …
Effectiveness Of Chinese Dual-Use Shipbuilding Within State-Owned Enterprises, Naveen Wineland
Effectiveness Of Chinese Dual-Use Shipbuilding Within State-Owned Enterprises, Naveen Wineland
Student Publications
This paper examines how effectively China’s state-owned enterprises (SOEs) have leveraged dual-use shipbuilding to support the naval modernization of the People’s Liberation Army Navy (PLAN). While China’s commercial shipbuilding sector now dominates the global market and provides SOEs with massive economies of scale, workforce continuity, and supply chain depth, the ability to translate these advantages into advanced naval shipbuilding has been uneven. Drawing on theoretical frameworks of the developmental state and hidden developmental state, this analysis distinguishes between commercial and naval shipbuilding requirements and examines hull-level production data for major U.S. and Chinese surface combatant classes. The evidence suggests that …
Building Reputation: State-Sponsored Rebellions And Transnational Identities, Marion Mercier, Arthur Silve, Benjamin Tremblay-Auger
Building Reputation: State-Sponsored Rebellions And Transnational Identities, Marion Mercier, Arthur Silve, Benjamin Tremblay-Auger
ESI Working Papers
States sometimes back rebellions abroad to signal resolve. We study this reputation-building logic in international relations, focusing on co-ethnic links between countries as an objective source of variation in a state’s incentives to demonstrate resolve. We formally derive two interconnected predictions from the mechanism: (a) a state is more likely to endorse the uprising of a foreign group when facing a larger audience, resulting in (b) greater political inclusion for the group. We build a comprehensive panel dataset of co-ethnic rebellion sponsorship, and find evidence consistent with both predictions.
Sullivan. V. Baker Ranches, Inc., 141 Nev. Adv. Op. 36 (2025), Andre Anaya
Sullivan. V. Baker Ranches, Inc., 141 Nev. Adv. Op. 36 (2025), Andre Anaya
Nevada Supreme Court Summaries
No abstract provided.
Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma To Radiotherapy, Cory M Richman, Alexandra Rasnitsyn, Borja L Holgado, Maria Vladoiu, Namal Abeysundara, Sandra Majo, Sara Chabi, Lucie J Taunay, Hiromichi Suzuki, Ichiyo Shibahara, Joonas Haapasalo, Jonelle G Pallotta, Tajana Douglas, Kaitlin Kharas, Kyle Juraschka, Oliver Ocsenas, Sachin A Kumar, Kristiina Nordfors, Ana Guerreiro Stücklin, Raul A Suarez, Jiao Zhang, Xiaochong Wu, Craig Daniels, Livia Garzia, Jüri Reimand, Olivier Saulnier, Thomas E Merchant, Celio Pouponnot, David R Raleigh, Michael D Taylor, Pasqualino De Antonellis
Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma To Radiotherapy, Cory M Richman, Alexandra Rasnitsyn, Borja L Holgado, Maria Vladoiu, Namal Abeysundara, Sandra Majo, Sara Chabi, Lucie J Taunay, Hiromichi Suzuki, Ichiyo Shibahara, Joonas Haapasalo, Jonelle G Pallotta, Tajana Douglas, Kaitlin Kharas, Kyle Juraschka, Oliver Ocsenas, Sachin A Kumar, Kristiina Nordfors, Ana Guerreiro Stücklin, Raul A Suarez, Jiao Zhang, Xiaochong Wu, Craig Daniels, Livia Garzia, Jüri Reimand, Olivier Saulnier, Thomas E Merchant, Celio Pouponnot, David R Raleigh, Michael D Taylor, Pasqualino De Antonellis
Faculty, Staff and Students Publications
Group 3 (G3) medulloblastoma constitutes the most aggressive molecular subgroup, and nearly all patients present with metastases upon recurrence. Treatment for newly diagnosed medulloblastoma relies on a combination of maximal safe surgical resection, followed by chemotherapy and ionizing radiation, and no therapies have been shown to confer a survival benefit at the time of recurrence. Given the limited therapeutic options available for patients with medulloblastoma, especially at recurrence, and the incomplete understanding of the molecular mechanisms underlying resistance to treatment, we sought to uncover actionable targets and biomarkers that could help refine patient selection and treatment of newly diagnosed medulloblastoma …
Protein Kinase Rock1 Activates Mitochondrial Fission Linking To Oxidative Stress And Muscle Atrophy, Meijun Si, Jihong Chen, Rizhen Yu, Hongchun Lin, Feng Li, Sungyun Jung, Sandhya S Thomas, Farhard R Danesh, Yanlin Wang, Hui Peng, Zhaoyong Hu
Protein Kinase Rock1 Activates Mitochondrial Fission Linking To Oxidative Stress And Muscle Atrophy, Meijun Si, Jihong Chen, Rizhen Yu, Hongchun Lin, Feng Li, Sungyun Jung, Sandhya S Thomas, Farhard R Danesh, Yanlin Wang, Hui Peng, Zhaoyong Hu
Faculty, Staff and Students Publications
Introduction: Chronic kidney disease (CKD) is associated with protein-energy wasting, characterized by a reduction in muscle mass and strength. Although mitochondrial dysfunction and oxidative stress are implicated in the pathogenesis of muscle wasting, underlying mechanisms remain unclear.
Methods: Here, we used transcriptomic analysis, metabolomics analyses, and mouse gene manipulation to investigate the effects of mitochondrial plasticity and oxidative stress on muscle wasting the subtotal nephrectomy mouse models of CKD. The mice with CKD were age- and sex-matched to sham-operated controls.
Results: Through these approaches, Rho-associated kinase ROCK1 emerged as a key molecule responsible for the observed mitochondrial fission and oxidative …
Examining Racial And Ethnic Disparities In Nurse Burnout, Intent To Leave, And Student Debt Burden: A Cross-Sectional Study, Jacqueline Christianson, Kyla Aiyeku, Abiola O. Keller
Examining Racial And Ethnic Disparities In Nurse Burnout, Intent To Leave, And Student Debt Burden: A Cross-Sectional Study, Jacqueline Christianson, Kyla Aiyeku, Abiola O. Keller
College of Nursing Faculty Research and Publications
Background:
A racially and ethnically diverse nursing workforce can only enhance the profession's ability to serve the widely diverse U.S. population. Embracing differences allows nurses to develop a broader understanding of each other and of their patients. Yet many nurses of color face unique challenges that can adversely impact their well-being and their longevity in this profession.
Purpose:
The purpose of this descriptive cross-sectional study was to examine levels of burnout, intent to leave the profession, and student debt burden among nurses who self-identified as Asian, Black or African American, or Hispanic, and compare these to the levels reported by …
The Power A Generation Holds: A Study On Students Generating Change In American Social Movements, Caroline E. Koziol
The Power A Generation Holds: A Study On Students Generating Change In American Social Movements, Caroline E. Koziol
Dartmouth College Master’s Theses
Social activism ebbs and flows throughout American history. In the contemporary period, high visual coverage of activism has contributed to frustrations over the apparent decrease in change despite perceptions of increased participation. Young activists in the classroom ask questions to learn from their predecessors. This paper focuses on answering, “How can students create sustained change through social activism?” The present work recenters activism in the role of students and higher education institutions, noting their potential for creating change through a formula for future activists to engage with. The proposed formula targets methods and theories to bolster success towards the cause …
Volumetric Differences Of Thalamic Nuclei Are Associated With Posttrauma Psychopathology, Jacklynn M. Fitzgerald
Volumetric Differences Of Thalamic Nuclei Are Associated With Posttrauma Psychopathology, Jacklynn M. Fitzgerald
Psychology Faculty Research and Publications
Background
Previous investigations of whole thalamus and thalamic nuclei volumes in posttrauma psychopathology have been sparse and limited in scope and have yielded inconsistent results. To address this, volumetric estimates of whole thalamus and thalamic nuclei were obtained from structural brain magnetic resonance imaging scans from 2058 participants across 20 worldwide sites in the ENIGMA (Enhancing Neuro Imaging Genetics through Meta Analysis) Posttraumatic Stress Disorder (PTSD) working group.
Methods
Thalamic volumes were compared in trauma-exposed participants with PTSD (n = 238), major depressive disorder (MDD) (n = 184), and comorbid PTSD+MDD (n = 618) and in trauma-exposed …
Masthead - Cardozo Arts & Entertainment Law Journal, Vol. 32 (2025-26)
Masthead - Cardozo Arts & Entertainment Law Journal, Vol. 32 (2025-26)
Cardozo Journal of Equal Rights & Social Justice
No abstract provided.
Burying Weapons Under The White Pine Tree: Reducing Nuclear Weapons And Using The Monetary Savings To Compensate Native Peoples Injured By The U.S. Nuclear Weapons Complex, William Y. Chin
Cardozo Journal of Equal Rights & Social Justice
No abstract provided.
When Executions Don't Kill: The Stories Of Eight People Who Survived Their Date With Death, Austin Sarat, Julia Morgan-Canales, Aidan Gemme
When Executions Don't Kill: The Stories Of Eight People Who Survived Their Date With Death, Austin Sarat, Julia Morgan-Canales, Aidan Gemme
Cardozo Journal of Equal Rights & Social Justice
This Article focuses on the eight people who have survived execution attempts in the last 100 years. Some of them faced a second attempt to carry out the sentence. Others escaped that fate only to die in prison; one reached an agreement with the state to allow them to remain in prison for the rest oftheir life, and the fate of another is up in the air.
By examining what went wrong in their executions and the accounts of those events offered by defense lawyers, state officials, and judges, this Article suggests that these executions fall into distinct genres. Each …
Can The Free Speech Clause Protect Transgender Expression From The Trump Administration?, Daniel Cooper
Can The Free Speech Clause Protect Transgender Expression From The Trump Administration?, Daniel Cooper
Cardozo Journal of Equal Rights & Social Justice
This Article explores how the Free Speech Clause can provide protection to speakers implicated by the Trump administration's executive orders restricting gender-related speech. Part I will provide an overview of how the Trump administration has directed executive authority to stifle gender-non-conforming identity and expression, how those efforts fit within the larger context of right-wing efforts to marginalize transgender people, and why the Equal Protection Clause of the Fourteenth Amendment to the United States Constitution is not currently a useful tool for the protection of trans rights. Part II will examine efforts to regulate government employees' pronoun usage, focusing on whether …
The Right To "Be Whole": A Jewish Religious Liberty Argument For Gender Affirming Care For Minors, Sarah Weiner
The Right To "Be Whole": A Jewish Religious Liberty Argument For Gender Affirming Care For Minors, Sarah Weiner
Cardozo Journal of Equal Rights & Social Justice
No abstract provided.
Splitting The Statute: Severability As A Canon Of Construction Or Constitutional Concern?, Amy L. Moore
Splitting The Statute: Severability As A Canon Of Construction Or Constitutional Concern?, Amy L. Moore
Law Faculty Scholarship
This Article examines the Supreme Court’s evolving severability doctrine and interrogates whether severability is best understood as a canon of statutory construction or as a constitutional limitation on judicial power. Tracing the doctrine from Marbury v. Madison through modern cases such as Champlin Refining Co., Carter Coal, INS v. Chadha, Alaska Airlines, Booker, and Seila Law, the Article demonstrates that the Court has oscillated between an interpretive presumption favoring preservation of legislative enactments and a structural concern about judicial lawmaking. It distinguishes between textual severability—excising unconstitutional statutory provisions—and application severability—limiting unconstitutional applications while preserving …
From Latent Patterns To Interpretable Subtypes: Machine Learning Driven Subtyping In Alzheimer’S Clinical Trials, Dulin Wang
Dissertations and Theses (Open Access)
Randomized controlled trials (RCTs) in neurodegenerative diseases often fail to show treatment benefits due to underlying patient variability. To overcome this challenge and improve clinical trial design, it is essential to identify responsive patient subgroups and understand distinct patterns of disease progression. This dissertation addresses these challenges by applying and developing advanced AI methodologies to Alzheimer’s Disease (AD) clinical trials. The first study investigates heterogeneous treatment effects (HTEs) across ten AD RCTs to identify responsive and non-responsive patient subgroups within trials previously considered negative or neutral. By implementing causal forests in ten AD clinical trials, this work reveals the HTEs …
The Evolution Of The Second Amendment And The American Gun Violence Epidemic: A Historical Analysis Of Political Self-Sabotage, Amanda Tureaud
The Evolution Of The Second Amendment And The American Gun Violence Epidemic: A Historical Analysis Of Political Self-Sabotage, Amanda Tureaud
Senior Theses
From the conception of the Bill of Rights until the 21st century, the Second Amendment was read and understood by the American population, both ordinary citizens and government officials, branches, and agencies inclusively, to allow the nation to have an armed military but not for private citizens to own and/or carry firearms. Since 2008, however, the Second Amendment has been interpreted as an absolute freedom for private citizens to own and carry semiautomatic assault weapons in the name of personal protection. This thesis holds that the evolution of society’s attitude on guns and gun control is specifically denoted by the …
Cul3 Postnatal Homozygous Deletion In Forebrain Results In Behavioral Differences, Prathibha Sekar, Qiang‐Qiang Xia, Alex C. Stokes, Feiyu Quan, Jeffrey Singer, Craig M. Powell
Cul3 Postnatal Homozygous Deletion In Forebrain Results In Behavioral Differences, Prathibha Sekar, Qiang‐Qiang Xia, Alex C. Stokes, Feiyu Quan, Jeffrey Singer, Craig M. Powell
Biology Faculty Publications and Presentations
Large-scale human genetic studies implicate multiple genes that regulate protein ubiquitination in autism spectrum disorder (ASD). De novo loss-of-function mutations in the gene CULLIN3 (CUL3) are implicated in autism and intellectual disability (ID). CUL3 is an essential component of an E3 ubiquitin ligase complex required for ubiquitination of substrates, often a signal for proteasomal degradation. Homozygous deletion of Cul3 is embryonically lethal. Recent studies show heterozygous deletion of Cul3 results in phenotypes with some face validity for autism in constitutive and conditional Cul3 heterozygotes. To understand the function of Cul3 in late postnatal development and function in the brain, we …
Synthesis And Characterization Of Lanthanide Extended Structures And Their Novel Transuranic Analogues, Hunter Bernard Tisdale
Synthesis And Characterization Of Lanthanide Extended Structures And Their Novel Transuranic Analogues, Hunter Bernard Tisdale
Theses and Dissertations
The United States owns a substantial amount of radioactive waste as a result of decades of research, weapons manufacturing, and nuclear energy production. As nuclear energy and research continue to add to our stockpiles of waste, the issue of remediating this waste becomes more pressing. Many of the radioactive constituents of this waste, such as the transuranic (Z > 92) elements, will give off radioactivity at harmful levels for millennia. Thus, a robust method of storing this waste is paramount to ensuring public safety. Currently, nuclear waste is being processed by vitrifying it in borosilicate glass. However, this method has shortcomings …
Creating A Resident And Fellow Scholarly Activity Tracking Tool In A Large Academic Health System: A Dissertation In Practice, Elyse Anne Wieszczecinski
Creating A Resident And Fellow Scholarly Activity Tracking Tool In A Large Academic Health System: A Dissertation In Practice, Elyse Anne Wieszczecinski
Theses and Dissertations
Documenting and reviewing resident and fellow scholarly activity within a sponsoring institution can be a laborious task. With multiple lines of information coming from a wide variety of sources, this problem of practice implemented the Information Systems Success Model to help develop a database by which this information can be collected in a way that is efficient while maintaining the need for a user-friendly product. While other healthcare entities have also incorporated this model into their scholarly activity collection, these are still individual needs of the sponsoring institution and its constituents to consider when adapting the strategy. Using an improvement …
Personal Finance Education In Florida: Teaching The Teachers, Jessica Morey
Personal Finance Education In Florida: Teaching The Teachers, Jessica Morey
Theses and Dissertations
This mixed-methods action research study with an explanatory sequential design investigated teacher financial capability and financial well-being in advance of a mandate that will require high school students in Florida to take a semester-long personal finance course, taught by social studies teachers. Survey results from 47 participants—teachers at a large suburban high school and high school social studies teachers across a Florida school district serving just over 29,000 students—indicated that while most teachers can answer basic financial literacy questions, many lack the financial self-efficacy to ensure their financial future. Teachers had varying experiences with financial socialization. While many had experienced …
Journey To Proficiency: The Impact Of Explicit Problem-Solving Instruction In A Fifth-Grade Math Classroom, Brittany J. Terry
Journey To Proficiency: The Impact Of Explicit Problem-Solving Instruction In A Fifth-Grade Math Classroom, Brittany J. Terry
Theses and Dissertations
This action research study examined the impact of explicit problem-solving instruction on fifth-grade students’ mathematics proficiency and attitudes across skill levels. At the outset, students relied on rote procedures rather than conceptual reasoning, limiting their ability to apply skills in new contexts or understand why procedures work. Grounded in constructivist and sociocultural learning theories, the study aimed to move students beyond procedural fluency through explicit instruction of problem-solving strategies, modeling, guided practice, collaboration, and reflection. Over 8 weeks, 32 students participated in daily lessons. Findings from pre–post assessments, interviews, and portfolios indicate that explicit problem-solving instruction supported measurable growth in …
The Role Of Language Ideologies In Saudi Elementary English Education: Efl Teacher’S Perspectives And Experiences, Ghanem Saad S Alghuwainem
The Role Of Language Ideologies In Saudi Elementary English Education: Efl Teacher’S Perspectives And Experiences, Ghanem Saad S Alghuwainem
Theses and Dissertations
This dissertation examines how Saudi elementary English teachers understand and enact language ideologies in a period of rapid educational change and national reform. Using a comparative case study of five teachers in Al-Ahsa, the study triangulates semi-structured interviews, classroom audio recordings, and teaching materials to compare stated beliefs with observable practice. The analysis is guided by the theories of English hegemony and language and gender ideology, which together illuminate how global linguistic hierarchies are localized through teachers’ beliefs and practices. Findings reveal that teachers occupy an ideologically complex position as they balance the national push for English proficiency under Vision …
A Qualitative Study Exploring Teachers’ Beliefs And Practices Supporting African American Male Readers, Rhonda Douglas Sumter
A Qualitative Study Exploring Teachers’ Beliefs And Practices Supporting African American Male Readers, Rhonda Douglas Sumter
Theses and Dissertations
Despite decades of educational reform, African American male students continue to experience persistent disparities in reading achievement. This qualitative case study explores the beliefs and pedagogical practices of three elementary educators identified as effective in supporting the reading development of African American males. Drawing on the frameworks of Culturally Relevant Pedagogy (Ladson-Billings, 1995) and Critical Race Theory (Delgado & Stefancic, 2012), the study seeks to illuminate how educators affirm students’ identities, maintain rigorous expectations, and create responsive learning environments that foster academic success.
Data sources included in-depth teacher interviews and classroom observations. Thematic analysis revealed three interconnected practices across cases: …