Digital Commons Network^™

Women's Work And Wealth: Measuring The Impact Of Incremental Liberations, 1850-1870, Hannah Kelly

Williams Honors College, Honors Research Projects

Using a two-way fixed effects difference-in-difference model, this project analyzes data from the IPUMS Full Count census for 1850, 1860, and 1870 at a state level for 48 states. Four models assess the impact of property laws on women's real property holdings, labor force participation, household types, and real property values.

By quantifying the impact of various legal reforms on women's economic empowerment, this project fills a gap in the understanding of the intersection between law, society, and women's economic agency during a transformative period in pre-industrial American history. These impacts can implicate the effectiveness of legislative measures in advancing …

Supporting Mothers Within The Criminal Legal System: Programs In Akron And Perceptions Of “Good Motherhood”, Brynn R. Lewis

Williams Honors College, Honors Research Projects

This paper examines the programs and support systems available in Akron, Ohio, for mothers involved in the criminal legal system, including defendants, survivors, and other justice-involved individuals. Using qualitative interviews (n = 6) with professionals across courts, legal defense, community corrections, and advocacy organizations, this study examines how local institutions provide resources and support to mothers. Findings indicate that while programs aim to promote stability and rehabilitation, mothers face persistent barriers such as limited access to transportation, childcare, and communication, as well as heightened stigma tied to societal expectations of caregiving. These findings reveal that institutional support both reflects and …

Synaptic Connectivity Of Rod Bipolar Cells In The Mouse Retina: A Connectomic Analysis Using Webknossos, Harold F. Eshun

Williams Honors College, Honors Research Projects

Rod bipolar cells (RBCs) are key interneurons in the mouse retina that transmit signals from rod photoreceptors to downstream amacrine and ganglion cells under scotopic (low-light) conditions. Although their general morphology and function are well established, the fine-scale organization of their synaptic inputs and outputs remains incompletely characterized. This project aims to map the pre- and postsynaptic partners of a fully reconstructed rod bipolar cell using the Yu volume, a serial block-face electron microscopy dataset from the ventral retina of an adult wild-type mouse. Using the webKnossos platform, I identify synaptic ribbons in the axon terminals of the rod bipolar …

Reconstructing Lost Voices, Lana Tamim

Williams Honors College, Honors Research Projects

This project uses digital text mining tools (OCR, NLP, sentiment analysis, and topic modeling) to analyze 19th–20th-century newspaper archives, focusing on how marginalized groups (women, immigrants, or labor workers) were historically portrayed. Many historical newspapers were dominated by elite voices, so this project aims to recover silenced or misrepresented perspectives by identifying hidden patterns in language, frequency of coverage, sentiment, and shifts in public perception over time. Using machine learning and visualization tools, the project will create interactive maps and timelines showing how representation evolved across regions.

Immigration As A Catalyst To The Far-Right: The Case Of Vox And Spain, Evelyn R. White

Williams Honors College, Honors Research Projects

Over the last decade or two, the world has witnessed a global rise in the popularity and success of far-right wing parties. This new era of the radical right raises questions of what is causing and fueling these political movements. Political Scientists have identified several contributing factors from the global economic crisis of 2008, the migrant crisis of 2015 and the global pandemic in 2020. This research paper aims to demonstrate how immigration acts as a catalyst to the far-right by intersecting with political science ideologies and other variables. The focus of this paper is how the Vox Party found …

Expanding State Tax Authority: Public And Private Sector Impacts Of Wayfair, Maxwell Pastoria

Williams Honors College, Honors Research Projects

The 2018 Supreme Court decision in South Dakota v. Wayfair, Inc. (Wayfair) overturned the longstanding physical presence rule for state sales tax collection, enabling states to enforce tax obligations on remote sellers through marketplace facilitator and economic nexus laws (Oyez, 2018). This study investigates the effects of these two post-Wayfair tax laws on state sales tax revenues, entrepreneurship, and public expenditures across all 50 states. Using a two-way fixed effects difference-in-differences (TWFE DID) framework, this research analyzes how policy adoption influenced per-capita outcomes in tax revenue, firm formation, and government spending in social services, education, infrastructure, and …

Pitch Report: Purdue Ivy Tech Chips Evaluation Report, Jennifer Sdunzik

Evaluation and Learning Research Center Reports

The Purdue Ivy Tech CHips (PITCH) program is a university-industry-community partnership aimed at developing an educational pipeline capable of providing a qualified workforce for the growing semiconductor industry in the region. Increasing student interest in microelectronics, awareness of current and future microelectronics careers, and self-efficacy to pursue microelectronics opportunities are foundational to building the industry’s workforce. The PITCH program addressed these needs by offering a summer experience that introduced high school students to the semiconductor industry.

The PITCH leadership team engaged Purdue's Evaluation and Learning Research Center (ELRC) to (1) identify (short and longer-term) impacts of the summer program on …

Locked And Loaded: The Truth Behind Gun Violence, Alana N. Shroyer

Williams Honors College, Honors Research Projects

Gun control remains one of the most controversial policy issues in the United States. While gun reform advocates argue for stricter firearm regulations to reduce gun violence, pro-gun advocates contend that crime is driven more by individual behavior, socioeconomic conditions, and mental health than by gun availability alone. This research project examines gun control laws in the United States, analyzes gun violence data, explores illegal firearm trade markets, compares international approaches, and evaluates whether gun control laws effectively reduce violence while preserving constitutional rights.

Parkland College Student Activities Of The Past (Exhibit Materials), Donica Swann

Library Scholarship

Poster and other exhibit materials celebrating 60 years of student life and activities at Parkland College. Special focus on The Prospectus, student organizations and clubs, and student government.

Self-Reported Psychological Effects Of Rock Climbing In Adults On The Autism Spectrum, Brennan Gleason

Honors Undergraduate Theses

Background: Prior research has shown rock climbing to have considerable therapeutic potential through such mechanisms as boosting self-esteem, promoting mindfulness, and creating a supportive social community. (Liu et al., 2022, Osborne et al., 2025). Meanwhile, autistic adults experience mood disorders at a significantly higher rate than the general population; upwards of 54% are diagnosed with a psychiatric condition (Croen et al., 2015). Many of the issues negatively affecting autistic adults align with the benefits of rock climbing, including low self-esteem, inadequate social support, and anxiety.

Objective: This study aimed to find differences in mental health outcomes between autistic adults who …

Health Care Governance And Structural Exclusion In Florida: A Human Rights Analysis Of Access For Latinx Communities, Natalie Medrano

Honors Undergraduate Theses

Access to health care in the United States is a complex system shaped by statutory programs and the discretionary powers of state governance. This thesis examines how Florida’s healthcare system structures access through administrative design, with particular attention to its impact on Latinx communities. Although formally race-neutral, Florida’s reliance on Medicaid non-expansion, managed care delivery, and complex eligibility processes produces systemic barriers that limit access for low-income populations. Drawing on the international right-to-health framework articulated in General Comment No. 14 of the International Covenant on Economic, Social and Cultural Rights, alongside Latinx Critical Race Theory (LatCrit), this study analyzes how …

Multicomponent Deoxyribozyme Probes For Targeted Detection Of Cancer Associated Gene Insertions, Samuel R. Veleke

Honors Undergraduate Theses

Insertions and deletions (indels) in DNA sequences of genes are linked with cancers such as glioblastoma (GB). Thus, indels may be used as potential cancer biomarkers. In the NANOG gene, its pseudogene NANOGP8 has a 22 base pair insertion sequence for GB patients. In this work, the NANOG gene and the insertion sequence were detected in one sample using a dual-fluorescent assay containing two multicomponent split deoxyribozyme (Dz) probe complexes. One complex used TXR fluorescence to detect the gene regardless of the insertion’s presence. The other complex used fluorescein (FAM) fluorophore to detect the insertion. The probes were able to …

Slay Her: The Rhetoric Of Violation In Buffy The Vampire Slayer, Lea N. Wright

Honors Undergraduate Theses

This research draws on feminist theory and monster theory to perform a close rhetorical analysis of incidents in the television show Buffy the Vampire Slayer (Buffy) where female characters are violated physically, psychologically, and/or sexually. Buffy is one of the most-analyzed television shows of all time, with a particular emphasis on the show’s engagement with feminism; however, the issue of violation has received little scholarly investigation despite multiple instances of it within the show. Through examining the rhetorical elements (such as dialogue, camerawork, body language, and character response) that surround incidents of violation, this research reveals that Buffy …

Gen Z Perspectives On Mental Health Service Interaction: A Qualitative Content Analysis Of Reddit Discourse, Victor A. Aguiar

Honors Undergraduate Theses

Compared to prior generations, Generation Z engages with mental health and mental health service interaction in distinct ways, frequently using social media platforms to share experiences, concerns, and opinions. Previous research has examined mental health discourse on Reddit; however, much of this work relies on inductive thematic approaches and offers limited focus on mental health service interaction and the factors influencing utilization. Guided by the Theory of Planned Behavior (TPB), this study examines how Generation Z discusses mental health service use through online discourse. Public Reddit posts authored by users identifiable as Generation Z, based on self-reported age, school enrollment, …

Tariffs And The Progressive Fiscal Constitution, Lawrence J. Liu, Alex Zhang

Faculty Articles

For more than a century, progressive taxation has constituted the American fiscal state. A resurgent and expanding tariff regime, however, threatens that commitment to progressive distribution. Given the ongoing popularity of tariffs, this Article examines how they might be designed and administered in a way that mitigates their regressive distributive impact. The Article thus develops and assesses proposals to (1) vary tariff burdens in accordance with the consumption of imported goods, (2) reduce income- or payroll-tax burdens on lower-income households, and (3) earmark tariff revenue for specified spending programs. Although none is perfect, we seek to articulate possibilities and highlight …

Pancreatic Cancer Detection Consortium Biomarker Bakeoff: A Phase Ii Blinded Biomarker Validation And Panel Discovery Study, Ann L. Oberg, William R. Bamlet, Grant Izmirlian, Seetharaman Balasenthil, Surinder K. Batra, Masataka Hayashi, Daniel S. Herman, Michael A. Hollingsworth, Maneesh Jain, Ann M. Killary, Brianna M. Krusen, Suyu Liu, Shounak Majumder, Gopalakrishnan Natarajan, Subrata Sen, Lynette M. Smith, Sudhir Srivastava, Brian M. Wolpin, Kenneth S. Zaret, Michael G. Goggins

Journal Articles: Biochemistry & Molecular Biology

PURPOSE: The Pancreatic Cancer Detection Consortium (PCDC) performed a blinded Early Detection Research Network-defined phase II biomarker bakeoff study of blood-based biomarker panels. The aims were to evaluate panel performance, to compare the panels' performance with that of cancer antigen 19-9 (CA19-9) alone, and to evaluate the performance of new combinations of the individual biomarkers.

EXPERIMENTAL DESIGN: Ten biomarkers representing eight biomarker panels and CA19-9 were evaluated using plasma, serum, and germline DNA from 140 stage I to IV pancreatic ductal adenocarcinoma (PDAC) cases and 140 controls from three tertiary care institutions, with controls frequency matched to cases on age …

Is Bruen The New Usery?, Tonja Jacobi, Cory Conley

Faculty Articles

In 2022, in New York State Rifle & Pistol Ass’n v. Bruen, the Supreme Court revolutionized the Second Amendment, achieving the long-held conservative goal of limiting gun restrictions by imposing an expansive, originalist view of the right to bear arms. However, within just three years, Bruen is showing cracks. Lower court judges are struggling mightily to apply it and are expressing their frustrations in exceptionally frank ways. And already the Supreme Court, in Rahimi v. United States, was forced to reconsider its approach. The Court has been here before, when it tried to revitalize the Tenth Amendment in …

Reclaiming Constitutional Authority Of Algorithmic Power, Yiyang Mei, Michael J. Broyde

Faculty Articles

Whether and how to govern AI is no longer a question of technical regulation. It is a question of constitutional authority. Across jurisdictions, algorithmic systems now perform functions once reserved to public institutions: allocating welfare, determining legal status, mediating access to housing, employment, and healthcare. These are not merely administrative operations. They are acts of rule. Yet the dominant models of AI governance fail to confront this reality. The European approach centers on rights-based oversight, presenting its regulatory framework as a principled defense of human dignity. The American model relies on decentralized experimentation, treating fragmentation as a proxy for democratic …

The Case For Friction In Ai-Mediated Information Seeking And Learning, Susan G. Archambault, Priya Kizhakkethil

Librarian Publications & Presentations

Introduction. This paper challenges the assumption that frictionless AI-mediated information seeking represents progress. We argue that AI systems eliminating productive friction, such as uncertainty, exploration, and reflective processes, undermine intellectual virtues essential for critical thinking in an AI-saturated information environment.

Method. This conceptual article employs a theory synthesis approach, drawing on library information science (LIS) theories of information behaviour, experience, and literacy, virtue epistemology, and human–computer interaction (HCI) friction design literature.

Analysis. We map intellectual virtues such as curiosity, thoroughness, and intellectual humility onto the Association of College and Research Libraries (ACRL) Framework for Information Literacy for Higher Education, building …

Grant-O-Thon: A Designathon-Informed Grant Writing Program To Enhance Research Grant Writing Skills In Low- And Middle-Income Countries, Yusha Tao, Gifty Marley, Lauren Fidelak, Bin Yu, Yusuf Babatunde, Anita N. Walker, Anthony A. Attama, Andrea L. Conroy, Esther K. Afolabi, Dimitrios N. Vatakis, Iheanyi Omezuruike Okonko, Shyngle K. Balogun, Hongyun Fu, Xin Peng, Ijeoma M. Ifeorah, Patience Kukundakwe, Alexandra Cossio, Ifeoma M. Obionu, Ángela Patricia Beltrán López, Matthew Idowu Olatubi, Ucheoma C. Nwaozuru, Yuanyi Chen, Huachun Zou, Eneyi E. Kpokiri, Daniil Wu, Oliver Ezechi, Juliet Iwelunmor, Meredith Labarda, Jason J. Ong, Weiming Tang, Joseph D. Tucker

Department of Pediatrics Faculty Publications

Problem

Early career researchers in low- and middle-income countries (LMICs) face substantial barriers when writing research grants and have limited writing support. A designathon approach was applied to organize a grant writing workshop (grant-o-thon) tailored for early-career LMIC researchers. This study describes the planning, implementation, and participant-reported outcomes of the grant-o-thon as a participatory training approach.

Approach

Grant-o-thons were organized in 2023, 2024, and 2025. Consistent with the designathon model, the grant-o-thon was structured in three stages: preparation using co-creation with end-users, intensive collaborative teamwork supported by mentor feedback and weekly writing deliverables, and structured follow-up. Each grant-o-thon consisted of …

Red-Sensitive Photopolymerizable Glass For Fabrication Of Holographic Optical Elements, Jamshed Aftab, Izabela Naydenova, Tatsiana Mikulchyk

Research Outputs: 2025-Present

Water-resistant photopolymerizable glass, which represents a photopolymerizable hybrid sol–gel (PHSG) material, has emerged as a compelling platform for holographic optical elements fabrication (HOEs), owing to its exceptional mechanical and thermal robustness with high holographic recording performance. Until now, PHSG compositions have been limited to blue/green-sensitive systems, despite significant interest in extending sensitivity into the red spectral region. Here, we report the first holographic photopolymerizable glass with sensitivity to red light, achieved through the incorporation of methylene blue (MB) as a photosensitizer and N-phenylglycine (NPG) as a co-initiator, with an optimal MB/NPG ratio of 1:150. This PHSG composition is capable of …

Preserving The Identity Of Historic Coptic Orthodox Monasteries In Egypt Under Contemporary Pressures: Case Studies Of St. Bishoy And St. Anthony Monasteries, George Medhat Adeeb, Mohamed Khairy Amin, Mohamed Ahmed Al-Sherbiny

Mansoura Engineering Journal

Historic Coptic Orthodox monasteries in Egypt (HCOMEs) represent an important component of Christian heritage, integrating architectural value with enduring spiritual traditions that reflect both tangible and intangible dimensions. However, contemporary development and changing functional demands are generating transformations that may affect their identity if not carefully managed. Despite extensive scholarship, limited research has systematically examined these transformations through a structured evaluative approach. This study addresses this gap by developing and applying an analytical and evaluation framework to examine how contemporary pressures influence the historical, architectural-spatial, and spiritual identity of HCOMEs, and to assess the effectiveness of monastic responses. The framework …

The Desecration Of Sacred Spaces In The Dead Sea Scrolls And Pre-Nicene Latin Christianity: A History Of Interpretation Of The Eschatological Motif Of The Defiling Enemy In Apocalypticism, Rodrigo De Galiza Barbosa

Dissertations

Problem

The motif of the polluting enemy in the sanctuary is an important point of departure in the articulation of community boundaries in Hebraic-Christian culture. This particular motif has the potential to explain, at least in part, how Jewish and Christian communities would have understood the apocalyptic evil other and, from this understanding, set boundaries for their holy communities. Texts such as Dan 8 and 2 Thess 2 have been the locus classicus of the so-called antichrist, and ever since their interpretation has shaped how Christians and Jews have understood the enemy to their respective communities. In the history of …

Dysregulation Of Alternative Splicing Patterns In The Ovaries Of Reproductively Aged Mice, Adnan T. Alsamaraee, Vanessa L. Correll, Julius O. Nyalwidhe, Pavla Brachova, Nehemiah S. Alvarez

Department of Biomedical and Translational Sciences Faculty Publications

Female reproductive aging is characterized by progressive deterioration of ovarian function, yet the molecular mechanisms driving these changes remain incompletely understood. Here, we used long-read direct RNA-sequencing to map transcript isoform changes in mouse ovaries across reproductive age. Comparing young and aged mice after controlled gonadotropin stimulation, we identified widespread alternative splicing changes, including shifts in exon usage, splice site selection, and transcript boundaries. Aged ovaries exhibited increased isoform diversity, favoring distal start and end sites, and a significant rise in exon skipping and intron retention events. Many of these age-biased splicing events altered open reading frames, introduced premature stop …

Cocaine Upregulates Microglial Lipid Droplet Formation Through Increasing Lipid Synthesis Activity In Vitro And In Vivo, Yan Cheng, Brooke Russell, Liam Liyang Guo, Aryan Patel, Yan Y. Sanders, Ming-Lei Guo

Department of Biomedical and Translational Sciences Faculty Publications

A novel subtype of microglia, lipid droplet accumulation microglia (LDAMs), has been identified in the aged brain, which is characterized by sustained inflammation and senescent-like phenotypes. LDAMs are deeply involved in promoting brain aging as well as the pathogenesis of multiple neurodegenerative diseases. Cocaine can alter brain lipidomic profiles, induce microglial activation, and accelerate brain aging. This suggests that cocaine might affect microglial lipid metabolism, which ultimately aggravates aging-related neurological disorders in people with addictions. In this study, we explored the effects of cocaine on microglial lipid metabolism. Our results showed that chronic cocaine administration altered brain lipid profiles and …

The Effects Of Abused Drugs On Ferroptosis Pathways: Potential Therapeutic Targets For Substance Use Disorders, Tamara Bouchard, Brooke Russell, Liam Liyang Guo, Tina Nguyen, Yan Cheng, Yan Y. Sanders, Ming-Lei Guo

Department of Biomedical and Translational Sciences Faculty Publications

Substance use disorders (SUDs) remain major public health concerns worldwide, particularly in developed countries. SUDs are characterized by persistent neuroinflammation and synaptic dysfunction in the brain. Despite decades of extensive investigation, the detailed mechanisms underlying SUDs remain elusive. Ferroptosis is a highly regulated cell death process deeply affected by iron metabolism, lipid peroxidation, reactive oxygen species (ROS) production, and antioxidant systems. It has been implicated in multiple neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and ischemic stroke. Recently, emerging evidence has highlighted the role of ferroptosis in drug-induced pathological changes. Various types of abused …

The Effects Of Abused Drugs On Ferroptosis Pathways: Potential Therapeutic Targets For Substance Use Disorders, Tamara Bouchard, Brooke Russell, Liam Liyang Guo, Tina Nguyen, Yan Cheng, Yan Y. Sanders, Ming-Lei Guo

Department of Biomedical and Translational Sciences Faculty Publications

Substance use disorders (SUDs) remain major public health concerns worldwide, particularly in developed countries. SUDs are characterized by persistent neuroinflammation and synaptic dysfunction in the brain. Despite decades of extensive investigation, the detailed mechanisms underlying SUDs remain elusive. Ferroptosis is a highly regulated cell death process deeply affected by iron metabolism, lipid peroxidation, reactive oxygen species (ROS) production, and antioxidant systems. It has been implicated in multiple neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and ischemic stroke. Recently, emerging evidence has highlighted the role of ferroptosis in drug-induced pathological changes. Various types of abused substances including alcohol, cocaine, …

Regulation Creations: A Trauma-Informed Resource Addressing Sensory And Socio-Emotional Childhood Challenges, Meagan Noel Barnes Pearson

Occupational Therapy Capstones

Introduction: Trauma is ubiquitous and can negatively impact many life outcomes. Though trauma can occur across the lifespan, particular emphasis has been placed on the outcomes of experiences that occur in childhood. Adverse childhood experiences (ACEs), as coined by Felitti et al. (1998), pertain to traumatic events that occur before the age of 18, and the correlation between the number of ACEs and poor health outcomes is significant. Children can begin demonstrating unfavorable symptoms upon becoming exposed to trauma. Current literature has illustrated particular differences in sensory systems and social skills for young children. These challenges can lead to hardship …

Legibility Grabs: Contesting Hegemony And Water Governance In Western Bahia, Brazil, Rowan A. Compton, Gustavo De L.T. Oliveira

Geography

This article examines how irrigated agribusiness interests in western Bahia, Brazil, are capturing the infrastructure of water governance itself — the basin committees, digital monitoring platforms, and fee structures through which water becomes visible and governable. Drawing on Gramscian theories of hegemony and James Scott's analysis of state legibility, we develop the concept of ‘legibility grabs’ to describe how dominant actors appropriate not only resources but the institutional mechanisms that render those resources objects of governance. Based on documentary analysis and 48 interviews conducted during fieldwork in 2024–2025, we demonstrate how agribusiness has waged wars of position within participatory institutions, …

Pollock: James Pollock Papers, Sdsu Archives And Special Collections, Hilton M. Briggs Library

Archives Finding Aids

The James Pollock Papers document the life, military service, artistic development, and professional activities of South Dakota artist James Pollock, with particular emphasis on his participation in the U.S. Army Combat Artists Program and his subsequent research into its history. The collection includes correspondence, journals, notebooks, interviews, reports, newspaper and magazine articles, exhibition materials, photographs, original sketches and artwork, prints, publications, audiovisual recordings, and memorabilia. Materials trace his development from student work at South Dakota State University through his military service and later career as an artist, illustrator, and photographer.

A substantial portion of the collection concerns Pollock's service with …