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Articles 10621 - 10650 of 1193039
Full-Text Articles in Entire DC Network
Redefining An Icon: Stadium Integration Into The Urban Center To Promote Community Engagement, Culture, And Identity In Dallas, Texas, Brandon Lee Peterson
Redefining An Icon: Stadium Integration Into The Urban Center To Promote Community Engagement, Culture, And Identity In Dallas, Texas, Brandon Lee Peterson
Architecture Theses
This thesis is an exploration into how stadium design can foster community engagement, cultural identity, and urban vibrancy in the United States. While many American stadiums often remain isolated from the urban fabric, located on city outskirts or suburbs and used solely for events, European models demonstrate the value of walkable, accessible, and integrated stadiums within mixed-use neighborhoods. Through a multidisciplinary review of urban design theory, economic factors, and programming needs, this research highlights the limitations of current U.S. stadium developments, such as issues of accessibility and underutilized public investment. Using a proposed downtown Dallas soccer stadium, the thesis offers …
Building On Memory: Towards A Digital Future Informed By Historical Theory, Lucas Laskow
Building On Memory: Towards A Digital Future Informed By Historical Theory, Lucas Laskow
Architecture Theses
This project synthesizes 2,000 years of architectural theory to establish an ethical framework for integrating artificial intelligence into contemporary design. The research culminates in “The Chandler,” demonstrating how AI can enhance, rather than replace, human-driven spatial and cultural values.
The assertion that human design is inherently superior to artificial intelligence relies on the flawed premise that intuitive leaps outweigh data-driven synthesis. Rather than diminishing the architect’s role, the evolution of AI demands that designers become ethical interpreters who ask the right questions. This project investigates how past architectural theorists, from Vitruvius’s foundational triad to Bruce Allsopp’s humanist return, provide a …
Architecture As A Camera: Utilizing Photographic Principles To Tell Stories Through Design, Ryan Gabriel Scherf
Architecture As A Camera: Utilizing Photographic Principles To Tell Stories Through Design, Ryan Gabriel Scherf
Architecture Theses
This thesis examines the relationship between memory, photography, and architecture as a framework for spatial design, framing memory as a fragmented phenomenon contingent upon light and time. Drawing on the theoretical work of Goffi, Barthes, and Bordeleau, it positions architecture as a temporal montage in which meaning emerges through layered absences, material “puncta,” and the interpretive gaps between fragments. Situated at the Botallack Mines in England, the project explores the intersection of photographic logic and industrial ruin by treating the site’s extractive history as a series of active fragments. Through compressed volumes and curated views, it translates photographic principles into …
Threads Of Recovery: Transforming Youth Residential Treatment Centers, Kathryn Fitzsimmons
Threads Of Recovery: Transforming Youth Residential Treatment Centers, Kathryn Fitzsimmons
Architecture Theses
This thesis explores how architecture can support adolescent mental health treatment through the design of a residential treatment center for youth ages ten to eighteen experiencing mental health crises. In response to increasing rates of anxiety, depression, and suicidal ideation among adolescents, the project examines the relationship between the built environment and emotional well being. The research critiques the legacy of the troubled teen industry, where institutional architecture often reinforced isolation and control rather than healing. Drawing from environmental psychology and analysis, the project proposes an alternative campus centered on safety, reflection, and community. The design, titled Threads of Recovery, …
“Thomas Jefferson: America’S Flawed Founder Of Freedom.”, Jay H. Buckley
“Thomas Jefferson: America’S Flawed Founder Of Freedom.”, Jay H. Buckley
Faculty Publications
Thomas Jefferson was a deeply paradoxical figure—both a founding champion of liberty and a lifelong slaveholder—whose legacy must be understood in its full complexity. While he owned more than 600 enslaved people and participated in a system he publicly condemned, Jefferson consistently articulated and promoted ideals of natural rights, equality, and freedom that reshaped the United States and influenced democratic movements worldwide. He made repeated (though often unsuccessful) efforts to curb or end slavery through legislation, legal cases, and policy, including opposing the slave trade, limiting slavery’s expansion into western territories, and helping abolish the transatlantic slave trade. At the …
2nd Place Research Paper: Shaping The Ape: Storytelling, Cultural Reflection, And Boundary Negotiation In Human-Ape Zoo Encounters, Abigail Bond Halling
2nd Place Research Paper: Shaping The Ape: Storytelling, Cultural Reflection, And Boundary Negotiation In Human-Ape Zoo Encounters, Abigail Bond Halling
Kevin and Tam Ross Undergraduate Research Prize
The typical Western zoo functions as a unique environment in which animals are frequently positioned as subjects of education and entertainment through the medium of storytelling. In this sense, the zoological institution can also be read as an extension of popular Western constructions surrounding nonhuman animals, particularly those who are symbolically charged characters in our collective imaginary– the great apes. Given the morphological, behavioral, and psychological similarities between humans and other great apes (chimpanzees, gorillas, and orangutans), nonhuman great ape enclosures at the Western zoo become spaces where humans are most radically confronted with navigating the boundaries of the “human-animal …
International Evidence-Based Guidelines For Traditional Chinese Medicine Management Of Allergic Rhinitis, Qin-Wei Fu, Peng Liu, Yan Ruan, Xin-Rong Li, Lan-Zhi Zhang, Sha-Sha Yang, Feng Chai, Ji Chen, Qiao-Yan Chen, Shu-Cheng Chen, Wen-Yong Chen, Yong-Na Chen, Hong-Bin Cheng, Lei Cheng, Lu-Jia Cui, Ke-Bin Deng, Cai-Shan Fang, Rong-Chang Feng, Li Fu, Wen-Yang Fu, Jian-Ying Gao, Hong Guo, Miao He, Ko-Hsin Hu, Chun-Jiang Huang, He-Yin Huang, Lu-Yun Jiang, Feng-Ying Qiao, Hui Leng, Yun-Ying Li, Chun-Song Liu, Da-Xin Liu, Jian-Hua Liu, Jin-Hui Liu, Jing Liu, Min Liu, Weiting Liu, Yuan-Xian Liu, Yang Liu, Ying Liu, Zhi-Qing Liu, Qiu-Lan Luo, Yu Ma, De-Hong Mao, Juan Meng, Kai-Yun Pang, Shun-Lin Peng, Xuan-Fu Tong, Ji Wang, Jia-Xi Wang, Jun-Ge Wang, Ren-Zhong Wang, Shi-Zhen Wang, Ji-Yan Xia, Hui Xie, Qiang Xie, Yan Xie, Da-Jing Xiong, Zhan-Feng Yan, Hui Yang, Da-Zheng Zhang, Fu-Bing Zhang, Shi-Peng Zhang, Zhi-Cheng Zhang, Ji-Ping Zhao, Yu Zhao, Yun Zheng, Dan-Zhu Zhong, Li Zhou, Valentin Mikhailovich Knyazev, Irina Viktorovna Kostrova, Wing-Fai Yeung, Qi Wang, De-Yun Wang, Qin-Xiu Zhang
International Evidence-Based Guidelines For Traditional Chinese Medicine Management Of Allergic Rhinitis, Qin-Wei Fu, Peng Liu, Yan Ruan, Xin-Rong Li, Lan-Zhi Zhang, Sha-Sha Yang, Feng Chai, Ji Chen, Qiao-Yan Chen, Shu-Cheng Chen, Wen-Yong Chen, Yong-Na Chen, Hong-Bin Cheng, Lei Cheng, Lu-Jia Cui, Ke-Bin Deng, Cai-Shan Fang, Rong-Chang Feng, Li Fu, Wen-Yang Fu, Jian-Ying Gao, Hong Guo, Miao He, Ko-Hsin Hu, Chun-Jiang Huang, He-Yin Huang, Lu-Yun Jiang, Feng-Ying Qiao, Hui Leng, Yun-Ying Li, Chun-Song Liu, Da-Xin Liu, Jian-Hua Liu, Jin-Hui Liu, Jing Liu, Min Liu, Weiting Liu, Yuan-Xian Liu, Yang Liu, Ying Liu, Zhi-Qing Liu, Qiu-Lan Luo, Yu Ma, De-Hong Mao, Juan Meng, Kai-Yun Pang, Shun-Lin Peng, Xuan-Fu Tong, Ji Wang, Jia-Xi Wang, Jun-Ge Wang, Ren-Zhong Wang, Shi-Zhen Wang, Ji-Yan Xia, Hui Xie, Qiang Xie, Yan Xie, Da-Jing Xiong, Zhan-Feng Yan, Hui Yang, Da-Zheng Zhang, Fu-Bing Zhang, Shi-Peng Zhang, Zhi-Cheng Zhang, Ji-Ping Zhao, Yu Zhao, Yun Zheng, Dan-Zhu Zhong, Li Zhou, Valentin Mikhailovich Knyazev, Irina Viktorovna Kostrova, Wing-Fai Yeung, Qi Wang, De-Yun Wang, Qin-Xiu Zhang
Research outputs 2022 to 2026
Allergic rhinitis (AR) is a prevalent chronic condition that significantly impacts patients' quality of life and poses challenges to effective management. Traditional Chinese medicine (TCM) offers a holistic approach, emphasizing syndrome differentiation, individualized care, and natural treatment strategies. To develop comprehensive evidence-based guidelines for AR management using TCM interventions, incorporating rigorous evidence assessment and expert consensus. The guidelines were developed using the GRADE-TCM framework, analyzing 351 randomized controlled trials (RCTs) involving 43,276 participants. Supplementary evidence from published textbooks, standardized documents, ancient literature, and TCM medical records was incorporated. Five rounds of expert consensus, involving 80 expert person-times and over 10,000 …
Unpacking American Reception Of Glocalized Non-English Content In The Netflix Era, Sur Govindarajan
Unpacking American Reception Of Glocalized Non-English Content In The Netflix Era, Sur Govindarajan
Dissertations
The swift growth of streaming services has revolutionized the worldwide distribution of media, making it possible for non-English and non-English-adjacent content to reach American consumers on a never-before-seen scale, which is sometimes perceived as an indication of increasing cultural tolerance. However, while a lot is known about what audiences see, far less is known about how they really understand and assess these stories. There is a fundamental vacuum in our understanding of audience reception as a lived, meaning-making process because previous research has mostly focused on consumption patterns. In order to close that gap, this study examines how American audiences …
Ptsd, Policy, And Passion: An Advocate's Autoethnographic Journey To Improve Veteran Care, Christopher L. Stansbury
Ptsd, Policy, And Passion: An Advocate's Autoethnographic Journey To Improve Veteran Care, Christopher L. Stansbury
Dissertations
Abstract
This autoethnographic study focuses on Post-Traumatic Stress Disorder (PTSD) among U.S. veterans and the policies and practices that impact life outcomes. The research answers the questions: (1) what insights emerge from the author’s embedded advocacy experience; (2) what systemic barriers impede veterans’ access to PTSD treatment; and (3) how does military culture shape help-seeking behavior. This research draws on the author’s multigenerational and institutional ties to military service—as descendant of a Korean-era veteran, Marine and Army servicemember, VA employee, and veteran advocate. The researcher constructs detailed autoethnographic and composite narratives of the lived experiences of service members who develop …
Attachment And Betrayal: Post-Infidelity Attachment Issues With A Focus On Gender, Taylor Forsythe
Attachment And Betrayal: Post-Infidelity Attachment Issues With A Focus On Gender, Taylor Forsythe
Electronic Theses and Dissertations
Infidelity represents a significant relational trauma that may disturb attachment processes such as trust, emotional intimacy, and closeness. There is a gap in the literature on how different infidelity exposures may relate to these attachment responses; more so, there is a dearth of information on the gender differences for attachment issues following any kind of infidelity. The purpose of this study aimed to examine differences in avoidant and anxious attachment across infidelity groups (no infidelity, non-sexual infidelity, sexual infidelity), and a further comparison of gender differences in those groups. Participants (N = 151) completed online surveys in a larger study …
Voices Of A New Era: A Discursive Psychology Study Of Influencer-Follower Discourse On Tiktok, Andrea Guerrero Hernandez
Voices Of A New Era: A Discursive Psychology Study Of Influencer-Follower Discourse On Tiktok, Andrea Guerrero Hernandez
Electronic Theses and Dissertations
The present study researched and investigated the discourse of five mega fashion influencers on TikTok, as well as the discourse of 15 followers engaging with fashion influencer content on the same platform. The theory used to guide this study was discursive psychology theory, which provided the groundwork for understanding how both influencers and followers position their identities, justify their actions and decisions, and construct their reality. The primary aim of this research is to deepen understanding of how influencer discourse shapes follower discourse, identifying recurring patterns, contradictions, and the ways in which tensions are negotiated. The findings reveal a range …
"Am I A Man Or A Muppet": A Rhetorical Analysis Of Generative Ai’S Representation Of Gender, Jessica Boaz
"Am I A Man Or A Muppet": A Rhetorical Analysis Of Generative Ai’S Representation Of Gender, Jessica Boaz
Electronic Theses and Dissertations
This thesis examines how generative artificial intelligence constructs and performs gender roles through a rhetorical analysis of the fully AI-generated podcast Fairytale Forensics. Drawing on theories of constitutive rhetoric, stereotyping, and McLuhan’s approach to the medium, this thesis investigates how AI-generated hosts interpret classic fairy tales while simultaneously reproducing and negotiating gender norms through the lens of prosopopoeia, metonymy and synecdoche. These performances rely on normative gender stereotypes that align with broader societal expectations, thereby potentially reinforcing existing cultural assumptions about masculinity and femininity. Ultimately, it demonstrates that AI-generated discourse does not merely reflect human biases but actively participates in …
Senior-Level Administrators’ Perceptions Of Deliberately Developmental Organization Principles And Employee Retention At Historically Black Colleges And Universities (Hbcus), Caprinia L. Taylor
Senior-Level Administrators’ Perceptions Of Deliberately Developmental Organization Principles And Employee Retention At Historically Black Colleges And Universities (Hbcus), Caprinia L. Taylor
Electronic Theses and Dissertations
Historically Black colleges and universities (HBCUs) have faced persistent challenges retaining qualified faculty and staff, threatening the environments they are uniquely positioned to create. High turnover, limited professional development, and inadequate support undermine employee well-being and student outcomes. This qualitative phenomenological study explored senior-level administrators’ perceptions of deliberately developmental organization (DDO) principles and their relevance to employee retention at HBCUs. Guided by DDO and organizational culture theory, the study examined how leadership practices, professional development, psychological safety, and organizational culture intersect with retention and belonging. Data were collected through semistructured interviews with participants across diverse HBCU contexts. Participants were selected …
Cultivating Diversity: Investigating Hispanic College Students’ Attitudes Toward Teaching Amid The U.S. Teacher Shortage Crisis, Daniela Andrea Hernandez
Cultivating Diversity: Investigating Hispanic College Students’ Attitudes Toward Teaching Amid The U.S. Teacher Shortage Crisis, Daniela Andrea Hernandez
Electronic Theses and Dissertations
The underrepresentation of Hispanic teachers in U.S. public education remains a significant concern as Hispanic students comprise a growing proportion of the K–12 population. Despite this demographic shift, the educator’s workforce has not reflected the cultural and linguistic backgrounds of the students it serves. The purpose of this qualitative descriptive study was to explore first- and second-year Hispanic college students’ perceptions of teaching as a profession and to examine how their educational and personal experiences influenced their career interests. The study was informed by social cognitive career theory and culturally relevant teaching theory to better understand how self-efficacy, outcome expectations, …
Noncanonical Clock Regulators Control Stress Responses In Digestive Diseases, Dishu Zhou, Roberto E López-Valiente, Samer G Mattar, Dongyin Guan
Noncanonical Clock Regulators Control Stress Responses In Digestive Diseases, Dishu Zhou, Roberto E López-Valiente, Samer G Mattar, Dongyin Guan
Faculty, Staff and Students Publications
The digestive system is essential for nutrient absorption, processing, and waste elimination. The expression of many genes and physiological processes within this system exhibits a 24-h rhythmicity. However, modern lifestyle factors, such as jet lag, shift work, and irregular eating patterns, significantly disrupt these rhythms, triggering various stress responses and contributing to numerous digestive disorders. Here, we focus on emerging studies on noncanonical clock regulators involved in stress responses, integrate these novel findings into the established model of the core circadian clock, and highlight recent advances in the development of novel therapeutics targeting these 24-h regulators. In addition, we discuss …
High-Penetrance Rare Variants Underlying Familial Lung Cancer Risk: Insights From Genetic Epidemiology Of Lung Cancer Consortium, Yanhong Liu, Yafang Li, Jinyoung Byun, Vikram R Shaw, Claudio Pikielny, Bo Peng, Chao Cheng, Spiridon Tsavachidis, Xiangjun Xiao, Dakai Zhu, Younghun Han, Ivan P Gorlov, Olga Y Gorlova, Michael Cole, Colette R Gaba, Erin L Crawford, Kristen Purrington, Ellen L Goode, Ping Yang, James Mckay, John K Field, Geoffrey Liu, Rayjean J Hung, Jun Xia, Jiyeon Choi, Matthew B Schabath, Jaclyn Lopiccolo, David C Christiani, Joan Bailey-Wilson, Ann G Schwartz, James C Willey, Diptasri Mandal, Susan M Pinney, Christopher I Amos
High-Penetrance Rare Variants Underlying Familial Lung Cancer Risk: Insights From Genetic Epidemiology Of Lung Cancer Consortium, Yanhong Liu, Yafang Li, Jinyoung Byun, Vikram R Shaw, Claudio Pikielny, Bo Peng, Chao Cheng, Spiridon Tsavachidis, Xiangjun Xiao, Dakai Zhu, Younghun Han, Ivan P Gorlov, Olga Y Gorlova, Michael Cole, Colette R Gaba, Erin L Crawford, Kristen Purrington, Ellen L Goode, Ping Yang, James Mckay, John K Field, Geoffrey Liu, Rayjean J Hung, Jun Xia, Jiyeon Choi, Matthew B Schabath, Jaclyn Lopiccolo, David C Christiani, Joan Bailey-Wilson, Ann G Schwartz, James C Willey, Diptasri Mandal, Susan M Pinney, Christopher I Amos
Faculty, Staff and Students Publications
Introduction: Rare, deleterious germline variants are key contributors to inherited lung cancer (LC) risk. The Genetic Epidemiology of LC Consortium (GELCC) has curated valuable high-risk LC families and is uniquely positioned to uncover rare, high-penetrance variants underlying familial LC (FLC).
Methods: We performed whole-genome and exome sequencing on germline DNA from 120 high-risk LC families (177 FLC cases, 309 unaffected relatives). We prioritized rare (allele frequency < 1% in the genome aggregation database), potentially deleterious variants present in two or more FLC cases. These variants were then validated in 10,085 sporadic LC (SLC) cases and 612,970 controls.
Results: We identified 118 candidate variants, 28 of which were validated in SLC with strong statistical support. We discovered a novel pathogenic axis of three truncating variants in GALNT6, MUC4, and ERBB3 genes, which …
Adhesion G Protein-Coupled Receptors, Tobias Langenhan, Garret R Anderson, Demet Araç, Gabriela Aust, Monserrat Avila-Zozaya, Sofie Morsing Bagger, Patrick Barth, Sandra Berndt, Stephen C Blacklow, Beatriz Blanco-Redondo, Antony A Boucard, James P Bridges, Lara-Sophie Brodmerkel, Kathleen M Caron, Yin Kwan Chung, Andrew N Dates, Virginea De Araujo Farias, Daniel Del Toro, Joseph G Duman, Felix B Engel, David M Favara, Caroline J Formstone, Chaoyu Fu, Alain Garcia De Las Bayonas, Anastasia Georgiadi, David E Gloriam, Randy A Hall, Jörg Hamann, Peter W Hildebrand, Cheng-Chih Hsiao, Bill X Huang, Jonathan A Javitch, Hee-Yong Kim, Robert J Kittel, Gunnar Kleinau, Richard Leduc, Ines Liebscher, Hsi-Hsien Lin, Joshua Linnert, Marie-Gabrielle Ludwig, David C Martinelli, Signe Mathiasen, Daniel Matúš, Mariam Melkumyan, Ana L Moreno-Salinas, Jan Mulder, Michael A Nash, Kasturi Pal, Daniel T Pederick, Nicole A Perry-Hauser, Xianhua Piao, Yu-Qi Ping, Dimitris G Placantonakis, Fabian Pohl, Simone Prömel, Mette M Rosenkilde, Laurent Sabbagh, Richard C Sando, Patrick Scheerer, Torsten Schöneberg, Elena Seiradake, Mareike Selcho, Florian Seufert, Abhishek K Singh, Georgios Skiniotis, Katja Spiess, Norbert Sträter, David Strutt, Thomas C Südhof, Jinpeng Sun, Gregory G Tall, Doreen Thor, Douglas G Tilley, Kimberley F Tolias, Mario Vallon, Erwin G Van Meir, Benoit Vanhollebeke, Giselle R Wiggin, Uwe Wolfrum, Jie Yan, Nathan A Zaidman, Yimin Zou, Nicole Scholz
Adhesion G Protein-Coupled Receptors, Tobias Langenhan, Garret R Anderson, Demet Araç, Gabriela Aust, Monserrat Avila-Zozaya, Sofie Morsing Bagger, Patrick Barth, Sandra Berndt, Stephen C Blacklow, Beatriz Blanco-Redondo, Antony A Boucard, James P Bridges, Lara-Sophie Brodmerkel, Kathleen M Caron, Yin Kwan Chung, Andrew N Dates, Virginea De Araujo Farias, Daniel Del Toro, Joseph G Duman, Felix B Engel, David M Favara, Caroline J Formstone, Chaoyu Fu, Alain Garcia De Las Bayonas, Anastasia Georgiadi, David E Gloriam, Randy A Hall, Jörg Hamann, Peter W Hildebrand, Cheng-Chih Hsiao, Bill X Huang, Jonathan A Javitch, Hee-Yong Kim, Robert J Kittel, Gunnar Kleinau, Richard Leduc, Ines Liebscher, Hsi-Hsien Lin, Joshua Linnert, Marie-Gabrielle Ludwig, David C Martinelli, Signe Mathiasen, Daniel Matúš, Mariam Melkumyan, Ana L Moreno-Salinas, Jan Mulder, Michael A Nash, Kasturi Pal, Daniel T Pederick, Nicole A Perry-Hauser, Xianhua Piao, Yu-Qi Ping, Dimitris G Placantonakis, Fabian Pohl, Simone Prömel, Mette M Rosenkilde, Laurent Sabbagh, Richard C Sando, Patrick Scheerer, Torsten Schöneberg, Elena Seiradake, Mareike Selcho, Florian Seufert, Abhishek K Singh, Georgios Skiniotis, Katja Spiess, Norbert Sträter, David Strutt, Thomas C Südhof, Jinpeng Sun, Gregory G Tall, Doreen Thor, Douglas G Tilley, Kimberley F Tolias, Mario Vallon, Erwin G Van Meir, Benoit Vanhollebeke, Giselle R Wiggin, Uwe Wolfrum, Jie Yan, Nathan A Zaidman, Yimin Zou, Nicole Scholz
Faculty, Staff and Students Publications
Adhesion G protein-coupled receptors (aGPCRs) constitute a structurally and functionally distinct group within the superfamily of GPCRs. In 2015, the International Union of Pharmacology invited the Adhesion GPCR Consortium to publish a comprehensive review about aGPCRs and establish a unified nomenclature. Since then, substantial progress has been made in delineating the biological roles, molecular architecture, biochemical properties, expression profiles, ligand repertoire, and activation and signaling strategies of aGPCRs. Commensurate with these advances, their relevance to human pathophysiology has become increasingly apparent. In a coordinated effort, the Adhesion GPCR Consortium has reviewed recent progress in this field and provides a comprehensive …
Adhesion G Protein-Coupled Receptors, Tobias Langenhan, Garret R Anderson, Demet Araç, Gabriela Aust, Monserrat Avila-Zozaya, Sofie Morsing Bagger, Patrick Barth, Sandra Berndt, Stephen C Blacklow, Beatriz Blanco-Redondo, Antony A Boucard, James P Bridges, Lara-Sophie Brodmerkel, Kathleen M Caron, Yin Kwan Chung, Andrew N Dates, Virginea De Araujo Farias, Daniel Del Toro, Joseph G Duman, Felix B Engel, David M Favara, Caroline J Formstone, Chaoyu Fu, Alain Garcia De Las Bayonas, Anastasia Georgiadi, David E Gloriam, Randy A Hall, Jörg Hamann, Peter W Hildebrand, Cheng-Chih Hsiao, Bill X Huang, Jonathan A Javitch, Hee-Yong Kim, Robert J Kittel, Gunnar Kleinau, Richard Leduc, Ines Liebscher, Hsi-Hsien Lin, Joshua Linnert, Marie-Gabrielle Ludwig, David C Martinelli, Signe Mathiasen, Daniel Matúš, Mariam Melkumyan, Ana L Moreno-Salinas, Jan Mulder, Michael A Nash, Kasturi Pal, Daniel T Pederick, Nicole A Perry-Hauser, Xianhua Piao, Yu-Qi Ping, Dimitris G Placantonakis, Fabian Pohl, Simone Prömel, Mette M Rosenkilde, Laurent Sabbagh, Richard C Sando, Patrick Scheerer, Torsten Schöneberg, Elena Seiradake, Mareike Selcho, Florian Seufert, Abhishek K Singh, Georgios Skiniotis, Katja Spiess, Norbert Sträter, David Strutt, Thomas C Südhof, Jinpeng Sun, Gregory G Tall, Doreen Thor, Douglas G Tilley, Kimberley F Tolias, Mario Vallon, Erwin G Van Meir, Benoit Vanhollebeke, Giselle R Wiggin, Uwe Wolfrum, Jie Yan, Nathan A Zaidman, Yimin Zou, Nicole Scholz
Adhesion G Protein-Coupled Receptors, Tobias Langenhan, Garret R Anderson, Demet Araç, Gabriela Aust, Monserrat Avila-Zozaya, Sofie Morsing Bagger, Patrick Barth, Sandra Berndt, Stephen C Blacklow, Beatriz Blanco-Redondo, Antony A Boucard, James P Bridges, Lara-Sophie Brodmerkel, Kathleen M Caron, Yin Kwan Chung, Andrew N Dates, Virginea De Araujo Farias, Daniel Del Toro, Joseph G Duman, Felix B Engel, David M Favara, Caroline J Formstone, Chaoyu Fu, Alain Garcia De Las Bayonas, Anastasia Georgiadi, David E Gloriam, Randy A Hall, Jörg Hamann, Peter W Hildebrand, Cheng-Chih Hsiao, Bill X Huang, Jonathan A Javitch, Hee-Yong Kim, Robert J Kittel, Gunnar Kleinau, Richard Leduc, Ines Liebscher, Hsi-Hsien Lin, Joshua Linnert, Marie-Gabrielle Ludwig, David C Martinelli, Signe Mathiasen, Daniel Matúš, Mariam Melkumyan, Ana L Moreno-Salinas, Jan Mulder, Michael A Nash, Kasturi Pal, Daniel T Pederick, Nicole A Perry-Hauser, Xianhua Piao, Yu-Qi Ping, Dimitris G Placantonakis, Fabian Pohl, Simone Prömel, Mette M Rosenkilde, Laurent Sabbagh, Richard C Sando, Patrick Scheerer, Torsten Schöneberg, Elena Seiradake, Mareike Selcho, Florian Seufert, Abhishek K Singh, Georgios Skiniotis, Katja Spiess, Norbert Sträter, David Strutt, Thomas C Südhof, Jinpeng Sun, Gregory G Tall, Doreen Thor, Douglas G Tilley, Kimberley F Tolias, Mario Vallon, Erwin G Van Meir, Benoit Vanhollebeke, Giselle R Wiggin, Uwe Wolfrum, Jie Yan, Nathan A Zaidman, Yimin Zou, Nicole Scholz
Faculty, Staff and Students Publications
Adhesion G protein-coupled receptors (aGPCRs) constitute a structurally and functionally distinct group within the superfamily of GPCRs. In 2015, the International Union of Pharmacology invited the Adhesion GPCR Consortium to publish a comprehensive review about aGPCRs and establish a unified nomenclature. Since then, substantial progress has been made in delineating the biological roles, molecular architecture, biochemical properties, expression profiles, ligand repertoire, and activation and signaling strategies of aGPCRs. Commensurate with these advances, their relevance to human pathophysiology has become increasingly apparent. In a coordinated effort, the Adhesion GPCR Consortium has reviewed recent progress in this field and provides a comprehensive …
Bridging Access Gaps In Radiotherapy: Knowledge-Based Planning In A Resource-Constrained Clinical Setting, Milton E Ixquiac Cabrera, Erick O Montenegro, Matthew Schmidt, Baozhou Sun, James A Kavanaugh, Taoran Li, Angel Velarde, Vicky De Falla, Francisco Reynoso
Bridging Access Gaps In Radiotherapy: Knowledge-Based Planning In A Resource-Constrained Clinical Setting, Milton E Ixquiac Cabrera, Erick O Montenegro, Matthew Schmidt, Baozhou Sun, James A Kavanaugh, Taoran Li, Angel Velarde, Vicky De Falla, Francisco Reynoso
Faculty, Staff and Students Publications
Background/purpose: Radiotherapy access in low- and middle-income countries (LMICs) is severely limited by shortages of trained personnel, high patient volumes, and large waiting times for manual treatment planning. Knowledge-based planning (KBP) has shown promise in high-income settings, yet its feasibility in resource-constrained environments remains underexplored. This study aimed to evaluate the feasibility of adapting a KBP model developed at a high-income institution for clinical use at Liga Nacional Contra el Cáncer (LNCC) in Guatemala for gynecological radiotherapy planning.
Materials and methods: A RapidPlan KBP model (Varian-Siemens Healthineers, Palo Alto, CA, USA) originally developed at Washington University in St. Louis using …
Risk Factors For The Development Of Food Allergy In Infants And Children: A Systematic Review And Meta-Analysis, Nazmul Islam, Alexandro W L Chu, Falana Sheriff, Farid Foroutan, Gordon H Guyatt, Romina Brignardello-Petersen, Paul Oykhman, Alfonso Iorio, Ariel Izcovich, Katherine M Morrison, Yetiani Roldan Benitez, Rachel J Couban, Dorota Borovsky, Yiming Zhang, Leonardo Ologundudu, Keerthana Pasumarthi, Syed Fahad Farooq, Kyle Tong, Wang-Choi Tang, Haseeb Faisal, Muhammad Faran Khalid, Mohammad Saad Asif, Shannon French, Susan Waserman, R Sharon Chinthrajah, Hugh A Sampson, S Shahzad Mustafa, Jay A Lieberman, Kirsi M Järvinen, Sally Bailey, Philippe Bégin, Scott H Sicherer, Jennifer Gerdts, Melanie Carver, Lynda Mitchell, Kelly Cleary, Matthew J Greenhawt, Julie Wang, Aikaterini Anagnostou, Marcus S Shaker, Anita Chandra-Puri, Patricia C Fulkerson, Robert A Wood, Derek K Chu
Risk Factors For The Development Of Food Allergy In Infants And Children: A Systematic Review And Meta-Analysis, Nazmul Islam, Alexandro W L Chu, Falana Sheriff, Farid Foroutan, Gordon H Guyatt, Romina Brignardello-Petersen, Paul Oykhman, Alfonso Iorio, Ariel Izcovich, Katherine M Morrison, Yetiani Roldan Benitez, Rachel J Couban, Dorota Borovsky, Yiming Zhang, Leonardo Ologundudu, Keerthana Pasumarthi, Syed Fahad Farooq, Kyle Tong, Wang-Choi Tang, Haseeb Faisal, Muhammad Faran Khalid, Mohammad Saad Asif, Shannon French, Susan Waserman, R Sharon Chinthrajah, Hugh A Sampson, S Shahzad Mustafa, Jay A Lieberman, Kirsi M Järvinen, Sally Bailey, Philippe Bégin, Scott H Sicherer, Jennifer Gerdts, Melanie Carver, Lynda Mitchell, Kelly Cleary, Matthew J Greenhawt, Julie Wang, Aikaterini Anagnostou, Marcus S Shaker, Anita Chandra-Puri, Patricia C Fulkerson, Robert A Wood, Derek K Chu
Faculty, Staff and Students Publications
Importance: The incidence and risk (predictive) factors for early life food allergy development remain uncertain.
Objective: To estimate the incidence and quantify risk factors for food allergy development.
Data sources: MEDLINE and Embase were systematically searched to January 1, 2025. Data were analyzed from June 1, 2025, to November 25, 2025.
Study selection: Incidence estimates included studies confirming food allergy via food challenge. Risk factor analyses included cohort, case-control, and cross-sectional studies in any language assessing children younger than 6 years using multivariable analyses.
Data extraction and synthesis: Paired reviewers independently extracted data. Random-effects meta-analyses pooled incidence and adjusted odds …
Fructose: Metabolic Signal And Modern Hazard, Richard J Johnson, Miguel A Lanaspa, Dean R Tolan, Marcus D Goncalves, Samir Softic, Kimber L Stanhope, Laura G Sánchez-Lozada, Mark A Herman, Joshua D Rabinowitz
Fructose: Metabolic Signal And Modern Hazard, Richard J Johnson, Miguel A Lanaspa, Dean R Tolan, Marcus D Goncalves, Samir Softic, Kimber L Stanhope, Laura G Sánchez-Lozada, Mark A Herman, Joshua D Rabinowitz
Faculty, Staff and Students Publications
There is much interest in the role of sweeteners such as table sugar (sucrose) and high-fructose corn syrup in obesity and metabolic disease. Both sweeteners consist of glucose and fructose, two six-carbon isomeric sugars. Whereas glucose ingestion may promote obesity through its effects to stimulate insulin secretion, fructose has unique metabolic effects that promote triglyceride synthesis and fat accumulation. These effects arise from fructose's well-known role as a signal of metabolic plenty. Under modern conditions of overnutrition, chronic excess fructose drives features of metabolic syndrome. Emerging evidence further links fructose to cancer and dementia. Here we review the biochemical, molecular …
Qualitative Phenomenography: Sustaining Motivations Of Black Women Principals In Pk-5 Title I Schools, Kahliah C. Rachel
Qualitative Phenomenography: Sustaining Motivations Of Black Women Principals In Pk-5 Title I Schools, Kahliah C. Rachel
Dissertations
Black women principals remain underrepresented in educational leadership, yet they are disproportionately assigned to PK-5 Title I schools, where complex academic, social, and political demands converge. Limited research examines what sustains these leaders over time, particularly in roles marked by intersecting oppressions of race and gender. Grounded in Black feminist thought and intersectionality, this qualitative phenomenographic study explored the sustaining motivations of six Black women who currently served or had served as principals in a PK-5 Title I school in Georgia. The purpose of this study was to describe the different ways these principals understood and experienced the internal and …
Exploring Alternative Curriculum Implementation In Special Education Settings, Amber R. Wilson
Exploring Alternative Curriculum Implementation In Special Education Settings, Amber R. Wilson
Dissertations
The purpose of this qualitative case study was to understand teachers’ perceptions of implementing an alternative curriculum in their self-contained special education settings and grade levels, as well as their perceptions of the training and ongoing support provided for its implementation. This study used a case study research design. Findings revealed that the participants experienced several challenges related to training, ongoing support, and curriculum implementation, including issues aligning the alternative curriculum with state standards and assessments. This study is significant because alternative curriculum implementation is under-researched in the United States, and the international literature on this topic is limited.
Political Legacies Of Malcolm X, Sumair Ahluwalia
Political Legacies Of Malcolm X, Sumair Ahluwalia
Theses
This study explores the ways in which Malcolm X’s legacy has been co-opted by various institutions and actors, including, but not limited to, politicians, historians, the general public, the federal government, and other commentators. As a result of this co-optation, Malcolm’s revolutionary ideals have been diluted or sanitized in the years since his assassination in 1965. Different approaches have been utilized to reframe Malcolm’s legacy, which include associating him with American liberalism, framing his arguments at the end of his life as markedly less radical, and external interference with popular works about Malcolm, including The Autobiography of Malcolm X. Additionally, …
The Making Of Shi'a Resistance In Afghanistan: Historical Roots, Communist Rule, And Soviet Occupation, 1978–1989, Sayed Sajjad Hojet
The Making Of Shi'a Resistance In Afghanistan: Historical Roots, Communist Rule, And Soviet Occupation, 1978–1989, Sayed Sajjad Hojet
Theses
This thesis examines Shi'a political mobilization in Afghanistan from the 1978 Saur Revolution through the Soviet occupation, ending in 1989. It argues that Shi'a resistance was not simply a religious reaction to Marxist rule but a complex movement shaped by long-term marginalization, influenced by rival political ideas, and connected to cross-border networks in Iran. It traces how persecution under Amir Abdurrahman Khan created a system of political exclusion that shaped Shi'a collective identity before the communist takeover, and how ideologies such Marxism and Political Islam further politicized Shi'a youth in the mid-twentieth century. The PDPA's coercive policies after 1978 helped …
Deep Reinforcement Learning-Based Equitable Post Disaster Resource Allocation Incorporating Social Vulnerability, Trevor John Mogaka
Deep Reinforcement Learning-Based Equitable Post Disaster Resource Allocation Incorporating Social Vulnerability, Trevor John Mogaka
Theses
Prior Deep Reinforcement Learning (DRL) approaches frame post‑disaster recovery as a sequential decision-making problem over infrastructure elements, using graph-based system models and resilience-oriented rewards. This thesis builds on an existing DRL framework by introducing a modified CDC Social Vulnerability Index (mCDC-SVI), developed using Max-min scaling, to quantify social vulnerability.A synthetic interdependent infrastructure testbed is divided into four socio‑economic regions using federal poverty and SNAP eligibility guidelines. The DRL simulation and Deep Q‑Network architecture are retrained under a multi-objective reward function that is efficiency-equity weighted (α:β). Agents are evaluated across unconstrained and constrained budget scenarios to examine how varying α and …
Immune Checkpoint Inhibitor-Associated Perioptic Neuritis, Neud Kiros, Alina Sinha, Anant Krishnan
Immune Checkpoint Inhibitor-Associated Perioptic Neuritis, Neud Kiros, Alina Sinha, Anant Krishnan
Conference Presentation Abstracts
Clinical History A 47-year-old male with history of stage IV gastric cancer on nivolumab presented with blurry vision worse at close distances. Binocular horizontal diplopia was found on exam. Fundus exam demonstrated 4+ disc edema and hemorrhage bilaterally. Recent head MRI was negative for leptomeningeal enhancement. MR venogram and MRI orbits with contrast were ordered as well as lumbar puncture. The patient’s next dose of immunotherapy was held. Opening pressure was normal, and MRV showed no evidence of dural sinus thrombosis. MRI of the orbits was positive for perioptic neuritis bilaterally, and the patient was started on a steroid taper …
Relationships Between Therapists And Diverse Children's Populations And Their Effects, Brenda Sanchez Vega
Relationships Between Therapists And Diverse Children's Populations And Their Effects, Brenda Sanchez Vega
Undergraduate Honors Theses
Roughly around 13.8% of children and adolescents in the United States receive some sort of counseling or therapy; the main focus of the research is on racial/ethnic minoritized children. Because APA’s ethical codes don’t address all possible situations, positive client-therapist relationships are bound to develop, including dyads or dual relationships, improving treatment progress. With the United States continuing to grow in diversity, there’s still a big gap in the literature surrounding minority children in therapy. Speculating if therapy approaches are used effectively for all children, including minoritized children. Based on past research already conducted, developing a positive client-therapist dual relationship …
Mechanistic Investigation Of Arsenic Removal From Drinking Water Using Metal–Organic Frameworks And Granular Activated Carbon, Mousa Almousa
Mechanistic Investigation Of Arsenic Removal From Drinking Water Using Metal–Organic Frameworks And Granular Activated Carbon, Mousa Almousa
Theses and Dissertations
Arsenic contamination in groundwater represents a critical environmental and public health challenge due to its high toxicity and widespread occurrence in natural aquifers. Chronic exposure to arsenic, even at trace levels, is associated with severe health effects, including skin lesions and increased cancer risk. Conventional treatment technologies, such as adsorption using activated carbon or metal oxides, often suffer from limited selectivity, regeneration difficulty, and reduced efficiency under varying pH conditions. Therefore, developing advanced sorbent materials with high capacity, selectivity, and structural stability is essential for addressing arsenic pollution in decentralized water systems.Metal–organic frameworks (MOFs) have recently emerged as promising materials …
Geochemical Modeling Of Co2 Sequestration In Saline Aquifer: Broom Creek Saline Aquifer, Lawrence Chima Asouzu
Geochemical Modeling Of Co2 Sequestration In Saline Aquifer: Broom Creek Saline Aquifer, Lawrence Chima Asouzu
Theses and Dissertations
Geological carbon sequestration in deep saline aquifers is widely regarded as a critical technology for mitigating anthropogenic CO₂ emissions. This dissertation presents a formation-specific, kinetically constrained reactive transport modelling study of CO₂ storage performance in the Broom Creek Formation, a quartz- and feldspar-dominated saline aquifer in the Williston Basin, North Dakota.
A high-resolution geological model was constructed in Petrel using well logs, well tops, and Sorensen’s permeability correlation, then exported via RESCUE file into CMG GEM for dynamic reactive transport simulation. The base-case scenario involved injection of CO₂ at 15 MMScf/day for one year, followed by 199 years of post-injection …