Digital Commons Network^™

Foundations Of Memory Capacity In Models Of Neural Cognition, Chandradeep Chowdhury

Master's Theses

A central problem in neuroscience is to understand how memories are formed as a result of the activities of neurons. Valiant’s neuroidal model attempted to address this question by modeling the brain as a random graph and memories as subgraphs within that graph. However the question of memory capacity within that model has not been explored: how many memories can the brain hold? Valiant introduced the concept of interference between memories as the defining factor for capacity; excessive interference signals the model has reached capacity. Since then, exploration of capacity has been limited, but recent investigations have delved into the …

The Tidal Prism, Viable Eelgrass Habitat, And The Effects Of Sea Level Rise In Morro Bay, Kaden A. Caliendo

Master's Theses

The tidal prism, or the volume of water exchanged from the sea to an estuary from mean low to mean high tide, influences system hydrodynamics and ecological functioning. Since 1884, the tidal prism in Morro Bay, California has been estimated to be decreasing over time due to sedimentation from upstream practices. What is the current tidal prism in Morro Bay and how will that change with sea level rise? How will eelgrass respond to rising sea levels?

For this study, inexpensive tidal gauges were deployed at four locations in Morro Bay from March to August 2023 to measure spatially varying …

The Biological, Physical And Chemical Response Of The Little Creek Watershed To The 2020 Czu Lighting Complex Fire, Natalie Fontana

Master's Theses

This post-fire study was conducted to characterize and observe fire induced changes in physical habitat parameters, water-quality conditions and macroinvertebrate assemblages in the Little Creek watershed, a tributary to Scotts Creek located in Cal Poly’s Swanton Pacific Ranch in Davenport, California. Pre-fire data was collected by a Cal Poly student, John Hardy, for his 2017 thesis. Post-burn bioassessment surveys for this study were repeated at four of the same study sites used by Hardy to provide comparisons to the California Stream Condition Index via a modified version of the State of California’s Surface Water Ambient Monitoring Program protocol. Macroinvertebrates were …

Diet Induced Metabolic Alterations In The Brain Tissues Of Juvenile Pigs With Non-Alcoholic Fatty Liver Disease, Rhesa Lacanienta

Master's Theses

The objective of this study was to investigate the diet-induced metabolic changes that affect the brain tissue of juvenile pigs with NAFLD. This study explored the liver- brain axis and metabolic markers in the frontal cortex (FC) affected by liver damage. 18 male (M) and 20 female (F) Iberian pigs were randomly allocated to 1 of 3 high-fructose high-fat liquid diets (lard, olive oil, and coconut oil) and fed for 10 consecutive weeks. “Healthy” Iberian pigs were fed a eucaloric diet to establish a physiological baseline. Protein precipitation extraction using ultra-performance liquid chromatography-tandem quadrupole mass spectrometry was performed for primary …

“Yo Sí Soy Boricua, Pa’ Que Tú Lo Sepas”: A Decolonial And Intersectional Analysis Of Alexandria Ocasio-Cortez, Jocelin Monge

Electronic Theses, Projects, and Dissertations

Historically speaking, political representation in Congressional districts in the U.S. has been predominantly White and male. Alexandria Ocasio-Cortez (AOC) is an example of a type of new mestizaconsciousness (Anzaldúa, 1987) given she is the youngest Latina congresswoman ever been elected to serve New York’s 14th Congressional District. This study employs an intersectional analysis on AOC’s viral moments with ‘The Squad’, Puerto Rico, Vogue, and Met Gala. Through a theoretical lens composed of elements of intersectionality (Crenshaw, 1991) and mestiza consciousness (Anzaldúa, 1987), this study focuses on three significant recurrent themes found in AOC’s estilos de resistencia or sensibilities …

Classification Of Large Scale Fish Dataset By Deep Neural Networks, Priyanka Adapa

Electronic Theses, Projects, and Dissertations

The development of robust and efficient fish classification systems has become essential to preventing the rapid depletion of aquatic resources and building conservation strategies. A deep learning approach is proposed here for the automated classification of fish species from underwater images. The proposed methodology leverages state-of-the-art deep neural networks by applying the compact convolutional transformer (CCT) architecture, which is famous for faster training and lower computational cost. In CCT, data augmentation techniques are employed to enhance the variability of the training data, reducing overfitting and improving generalization. The preliminary outcomes of our proposed method demonstrate a promising accuracy level of …

Lung Lesion Segmentation Using Deep Learning Approaches, Sree Snigdha Tummala

Electronic Theses, Projects, and Dissertations

The amount of data generated in the medical imaging field, especially in a modern context, is growing significantly. As the amount of data grows, it's prudent to make use of automated techniques that can leverage datasets to solve problems that are error-prone or have inconsistent solutions.

Deep learning approaches have gained traction in medical imaging tasks due to their superior performance with larger datasets and ability to discern the intricate features of 3D volumes, a task inefficient if done manually. Specifically for the task of lung nodule segmentation, several different methods have been tried before such as region growing etc. …

The Space Between, Alexander Dixon

Electronic Theses, Projects, and Dissertations

The Space Between investigates the intricate relationship between perception and reality. By integrating graphic design principles with the optical qualities of glass, the exhibition creates visual distortions that challenge and redefine our understanding of the world. The pervasive use of black throughout the exhibition signifies the vectorized image, a vital element of graphic design and the technological abyss prevalent within our society. The fundamental geometric shapes, coupled with minimalist sculptural forms, employ a graphic approach to highlight visual communication's influence on perception.

Graphic design has a history of shaping public perception. The basis of graphic design is the act of …

Gastrointestinal Distress As A Potential Mediator Between Stress And Periodontal Inflammation, Casey D. Wright, Brenda Heaton, Raul I. Garcia, Maureen M. Leonard, Alessio Fasano, Daniel W. Mcneil

School of Dentistry Faculty Research and Publications

Objectives

Periodontal disease is multifactorial in its aetiology, which encompasses biopsychosocial contributors, including psychological stress. Gastrointestinal distress and dysbiosis have been associated with several chronic inflammatory diseases yet have rarely been investigated with respect to oral inflammation. Given the implications of gastrointestinal distress on extraintestinal inflammation, this study aimed to evaluate the potential role of such distress as a mediator between psychological stress and periodontal disease.

Methods

Utilizing a cross-sectional, nationwide sample of 828 adults in the USA generated via Amazon Mechanical Turk, we evaluated data collected from a series of validated self-report psychosocial questionnaires on stress, gut-specific anxiety around …

Identifying Trauma Related Predictors Of Dissociation In Maltreated Youth, Amanda L. Mraz

UNLV Theses, Dissertations, Professional Papers, and Capstones

Maltreated youth who experience traumatic dissociation are at an increased risk for various psychopathological difficulties. Much is still unknown about the machinations behind experiences of dissociation post-trauma. This study aimed to identify variables that place maltreated youth at risk for experiencing traumatic dissociation (e.g., dissociative amnesia, absorption and imaginative involvement, passive influence, depersonalization and derealization, and total adolescent dissociative experiences symptoms (A-DES)). Investigatory variables included demographic (e.g., age, gender, and racial identity), cognitive (e.g., resiliency and posttraumatic cognitions), and psychological (e.g., posttraumatic stress disorder symptoms (PTSD) and anxiety) factors. Classification and regression tree (CART) analysis was utilized to observe the …

Assessing The Risk Of West Nile Virus In The Southwestern United States, Bradon Bucher

UNLV Theses, Dissertations, Professional Papers, and Capstones

Climate change is an increasing public health threat that has been shown to influence Culex mosquito populations, the vectors of West Nile Virus (WNV). The main objective of this study was to determine which variables are most associated with WNV in the Southwest United States, defined herein as: California, Nevada, Arizona, and Utah. A Poisson regression model was used to analyze total cases from 2004-2020 using the following predictors: mosquito season temperature average, mosquito season precipitation average, bodies of water, and protected lands. Results indicated that precipitation average (P =.014) and the interaction between precipitation and temperature (P=.024) were significant. …

Unraveling Water Quality Issues In The Colorado River Basin: Utilizing Remote Sensing Satellite Images, Statistical, And Machine Learning For Improved Monitoring, Godson Ebenezer Adjovu

UNLV Theses, Dissertations, Professional Papers, and Capstones

This research was aimed at exploring innovative and cost-effective tools in understanding the spatiotemporal variability of water quality parameters in the Colorado River Basin (CRB), which includes the Colorado River and major reservoirs and lakes in the USA including Lake Mead. The river which arises in the state of Colorado and empties into the Republic of Mexico at the Gulf of California, is a source of water to seven US states and the Republic of Mexico and provides water to about 40 million people and million acres of farmlands in seven states in the western US and the Republic of …

Factors Associated With Caregiver Responsive And Non-Responsive Feeding Styles In Clark County, Nevada, Amanda Castelo Saragosa

UNLV Theses, Dissertations, Professional Papers, and Capstones

Early childhood obesity has increased significantly over the last few decades, reaching epidemic levels in the United States. Many interventions exist to alleviate early childhood obesity; however, little focus is on preventing obesity-related risks for children under two. High-quality child-caregiver interactions are deemed critical for preventing early childhood obesity development, but there is little information on the socio-ecological factors that influence a caregivers' feeding styles. This study examined socio-ecological factors associated with caregivers' feeding styles (responsive vs. non-responsive) for infants under two in Clark County, Nevada. This cross-sectional study utilized a survey targeted to caregivers (18 and older) with infants …

Examining Emotion Regulation Strategies As Predictors Of Posttraumatic And Depressive Symptomatology In Maltreated Youth, Kinsey Ellis

UNLV Theses, Dissertations, Professional Papers, and Capstones

Youth with a history of maltreatment victimization are at heightened risk for developing symptoms of posttraumatic stress and depression. Recent work has identified emotion dysregulation as a potential transdiagnostic mechanism linking maltreatment victimization to youth psychopathology, but few studies have examined the influence of specific emotion regulation strategies. Habitual utilization of expressive suppression and cognitive reappraisal have each demonstrated associations with trauma-related psychopathology in adults. The present study examined both strategies as predictors of posttraumatic and depressive symptomatology in youth with a history of maltreatment, as well as mediators in the relationship between the two conditions.

The sample included 133 …

Examining Covid-19 Vaccine Hesitancy Among The Nevada African American Population Using The Social-Ecological Model, Katelyn Faulk

UNLV Theses, Dissertations, Professional Papers, and Capstones

In Nevada, COVID-19 vaccines have been widely available to the general population since March 2021; however, even with the wide availability of these vaccines only 40% of the African American population in Nevada has been fully vaccinated against COVID-19 as of May 2023. This is problematic as it has been shown that the African American population is disproportionately affected by COVID-19 with higher rates of cases, hospitalizations, and deaths when compared to other races or ethnicities. Through the literature, it has also been well documented that African Americans may experience hesitancy toward these vaccinations for a multitude of reasons including …

Scalable Algorithm Design And Performance Analysis For Graph Motifs Discovery, Md Abdul Motaleb Faysal

UNLV Theses, Dissertations, Professional Papers, and Capstones

Discovering motifs or structural patterns, such as communities, is a significant graph application utilized for classifying groups in social and business networks, identifying similar proteins, detecting anomalous behavior in the cybersecurity domain, and finding critical entities in rumor propagation or infectious disease spreading. Existing state-of-the-art techniques for community discovery face challenges related to scalability, performance limitations, and methodological inaccuracies. The objective of this doctoral dissertation is to introduce novel parallel algorithms and propose high-performance computing architecture designs to address the performance constraints of current community detection approaches when processing large-scale social and biological data. This research focuses on two main …

Investigating A Passive Treatment System For The Removal Of Nutrients From Urban Runoff, Jasminn Gray

UNLV Theses, Dissertations, Professional Papers, and Capstones

The Environmental Protection Agency recognizes urban runoff as a major contributor of surface water pollution with nutrients as the second largest cause of surface water impairment in the United States. While a water quality standard of 100 lbs/day total phosphorus load allocation for all nonpoint sources is permitted for the Las Vegas Valley (LVV) under the National Pollutant Discharge Elimination System, currently there is not a counterpart standard for nitrogen. With the continued development of the LVV and the depletion of the quantity of water in Lake Mead due to the ongoing drought, the concentrations of phosphorus and nitrogen species …

Virus Removal And Characterization During Secondary Treatment At A Full-Scale Plant, Tyler Hill

UNLV Theses, Dissertations, Professional Papers, and Capstones

Virus removal is paramount to water reuse applications and nearly all water reuse applications require extensive pathogen reduction because of high influent concentration, difficulty of detection and distinguishing infectivity. Typically, regulations stipulate virus attenuation that require the implementation of multi-barrier advanced treatment trains and award these reductions in log notation called log reduction values (LRVs). Reduction of virus concentrations are not awarded for virus removal that may occur in wastewater treatment steps which precede water reuse units such as activated sludge secondary biological treatment.

A systematic literature review was performed and virus reduction at full-scale wastewater treatment plan was monitored …

Comparison Of Male And Female Ultramarathon Runners, Kelsey Klug

UNLV Theses, Dissertations, Professional Papers, and Capstones

This research study investigates how specific running variables and demographic characteristics impact performance, or speed, for ultramarathon runners. These variables and characteristics include biological sex, cadence, age range, total distance of the race, duration of the race, years of running experience, total number of ultramarathon races ever completed, and number of races completed in the last twelve months. An ultramarathon is any running distance over a standard marathon or 42.2 kilometers. Participation in ultramarathons has increased by 345% since 2010, with females making up 23% of participants. No in-person data collection was necessary for this study. Participants were asked to …

Evolution And Natural Selection Of Olfactory Receptor Genes In Hawaiian Drosophila, Ngoc H. Ly

UNLV Theses, Dissertations, Professional Papers, and Capstones

The olfactory system is a powerful tool for sensing countless odorants. In Drosophila, the olfactory system is critical for detecting food, finding mates, laying eggs, avoiding predators, and adapting to new environments. Understanding the olfactory system in Drosophila will advance our knowledge of sensory biology in various insects and vertebrates, including humans. Drosophila has been a valuable model for biology since the early 1900s, and the Drosophila melanogaster olfactory system is well-studied. The Hawaiian Drosophila represent approximately 1/3 of the world’s Drosophila, however, there is limited research on Hawaiian Drosophila olfactory genes. We conducted a comparative analysis of …

Profiles Of Cross-Domain Motivational Beliefs: Relations With Engagement And Gender, Alireza Maghsoudlou

UNLV Theses, Dissertations, Professional Papers, and Capstones

A central tenet of expectancy-value theory is that individuals’ relative expectancies and values across multiple academic domains influence their achievement-related outcomes. However, few studies have investigated how expectancy-value beliefs in multiple domains combine within individuals and how such motivational configurations are related to engagement. In this study, a person-centered approach was employed to identify and evaluate naturally occurring combinations of motivational beliefs among 3,928 fourth-grade students. Leveraging TIMSS and PIRLS database of 2011, I examined profiles of students’ math, reading, and science self-concept and interest value and their relations with engagement in these domains. Additionally, I examined gender as predictors …

Compassion, Oxytocin, And Simulation Experiences Among Prelicensure Nursing Students, Shelley L. Price

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: Compassion is a core competency and the philosophical foundation of nursing. Previous studies demonstrated that uncompassionate nursing care was associated with increased patient morbidity and mortality, prolonged illness and recovery, and missed care opportunities. However, it is unknown whether prelicensure nursing education contributes to greater compassion levels among prelicensure nursing students (PNSs). Aims: These studies addressed three research aims: (1) Describe and compare levels of compassion in first-term and last-term PNSs, (2) Determine the effects of a compassion-inducing simulation event on compassion in PNSs, as measured through a survey and biological measurement, and lastly, (3) Investigate the relationship between …

Engineered Biomass-Derived Carbon Adsorbents For Targeted Contaminant Remediation From Aqueous Environments, Suraj Venkat Pochampally

UNLV Theses, Dissertations, Professional Papers, and Capstones

Porous carbon adsorbents like biochar (BC) are produced from waste biomasses like wood chips, animal litter, nut shells, dried grass, etc. to be used in a multitude of applications like gas capture, soil amendment, water treatment, electrode materials, etc. In water treatment, carbon-based adsorbents have been mainly used to physically or chemically adsorb contaminants depending on the adsorption mechanism. However, BCs in their raw state do not have the capability of absorbing high amounts of contaminants and need to be activated/ modified for the pore network to broaden and adsorb the contaminants with better efficiency.

The scope of this dissertation …

Treatment Of Oxyanion Contaminants From Waste Brine Streams Using Halophilic/Halotolerant Microorganisms, Yasaman Saedi

UNLV Theses, Dissertations, Professional Papers, and Capstones

Brine waste streams are a current environmental issue given their high concentrations of contaminants and total dissolved solids (TDS), specifically sodium and chloride. Developing technologies that address brine treatment challenges is an essential need for water and wastewater industries. In addition to high salinity industrial wastes, there are several water treatment technologies producing brine waste streams in high volumes including reverse osmosis (RO), membranes, and Ion-exchange. With rising water demands and decreasing water supply, RO membranes will be extensively employed for potable water reuse and water desalination. Reusable ion exchange resins are also widely used to remove oxyanions contaminants from …

Associations Between Avocado Intake And Measures Of Glucose And Insulin Homeostasis In Hispanic Individuals With And Without Type 2 Diabetes: Results From The Hispanic Community Health Study/Study Of Latinos (Hchs/Sol), Mackenzie K Senn, Mark O Goodarzi, Gautam Ramesh, Matthew A Allison, Mariaelisa Graff, Kristin L Young, Gregory A Talavera, Amanda C Mcclain, Tanya P Garcia, Jerome I Rotter, Alexis C Wood

Faculty, Staff and Students Publications

BACKGROUND AND AIMS: To investigate associations between avocado intake and glycemia in adults with Hispanic/Latino ancestry.

METHODS AND RESULTS: The associations of avocado intake with measures of insulin and glucose homeostasis were evaluated in a cross-sectional analysis of up to 14,591 Hispanic/Latino adults, using measures of: average glucose levels (hemoglobin A1c; HbA1c), fasting glucose and insulin, glucose and insulin levels after an oral glucose tolerance test (OGTT), and calculated measures of insulin resistance (HOMA-IR, and HOMA-%β), and insulinogenic index. Associations were assessed using multivariable linear regression models, which controlled for sociodemographic factors and health behaviors, and which were stratified by …

Biallelic Med27 Variants Lead To Variable Ponto-Cerebello-Lental Degeneration With Movement Disorders, Reza Maroofian, Rauan Kaiyrzhanov, Elisa Cali, Mina Zamani, Maha S Zaki, Matteo Ferla, Domenico Tortora, Saeid Sadeghian, Saadia Maryam Saadi, Uzma Abdullah, Ehsan Ghayoor Karimiani, Stephanie Efthymiou, Gözde Yeşil, Shahryar Alavi, Aisha M Al Shamsi, Homa Tajsharghi, Mohamed S Abdel-Hamid, Nebal Waill Saadi, Fuad Al Mutairi, Lama Alabdi, Christian Beetz, Zafar Ali, Mehran Beiraghi Toosi, Sabine Rudnik-Schöneborn, Meisam Babaei, Pirjo Isohanni, Jameel Muhammad, Sheraz Khan, Maha Al Shalan, Scott E Hickey, Daphna Marom, Emil Elhanan, Manju A Kurian, Dana Marafi, Alihossein Saberi, Mohammad Hamid, Robert Spaull, Linyan Meng, Seema Lalani, Shazia Maqbool, Fatima Rahman, Jürgen Seeger, Timothy Blake Palculict, Tracy Lau, David Murphy, Niccolo Emanuele Mencacci, Katharina Steindl, Anais Begemann, Anita Rauch, Sinan Akbas, Ayça Dilruba Aslanger, Vincenzo Salpietro, Hammad Yousaf, Shay Ben-Shachar, Katarina Ejeskär, Aida I Al Aqeel, Frances A High, Amy E Armstrong-Javors, Seyed Mohammadsaleh Zahraei, Tahereh Seifi, Jawaher Zeighami, Gholamreza Shariati, Alireza Sedaghat, Samaneh Noroozi Asl, Mohmmad Shahrooei, Giovanni Zifarelli, Lydie Burglen, Claudia Ravelli, Johannes Zschocke, Ulrich A Schatz, Maryam Ghavideldarestani, Walaa A Kamel, Hilde Van Esch, Annette Hackenberg, Jenny C Taylor, Lihadh Al-Gazali, Peter Bauer, Joseph J Gleeson, Fowzan Sami Alkuraya, James R Lupski, Hamid Galehdari, Reza Azizimalamiri, Wendy K Chung, Shahid Mahmood Baig, Henry Houlden, Mariasavina Severino

Faculty, Staff and Students Publications

MED27 is a subunit of the Mediator multiprotein complex, which is involved in transcriptional regulation. Biallelic MED27 variants have recently been suggested to be responsible for an autosomal recessive neurodevelopmental disorder with spasticity, cataracts and cerebellar hypoplasia. We further delineate the clinical phenotype of MED27-related disease by characterizing the clinical and radiological features of 57 affected individuals from 30 unrelated families with biallelic MED27 variants. Using exome sequencing and extensive international genetic data sharing, 39 unpublished affected individuals from 18 independent families with biallelic missense variants in MED27 have been identified (29 females, mean age at last follow-up 17 ± …

Climate Change And The Shifting Geography Of Coral-Reef Development, Victor Rodriguez-Ruano

Theses and Dissertations

Coral-reef development is modulated by growth processes that deposit calcium carbonate onto the reef, such as calcification, and destructive processes that remove calcium carbonate from the reef, such as bioerosion. Wherever calcification rates exceed bioerosion rates, there is a net accretion of the reef through time, but where bioerosion rates exceed calcification rates, there is a net destruction of the reef through time. A reef’s framework is the legacy of the interaction of these processes throughout a reef’s history. Studying the fossil frameworks of reefs can shed light on the environmental factors that have controlled reef development in the past, …

Investigating The Effects Of Collagen Alignment And Tricalcium Phosphate Incorporation On Osteoblast Cell Response, Kathryn Elizabeth Bock

Theses and Dissertations

Every year, over 20 million people globally are affected by bone tissue loss due to disease or trauma. Bone tissue engineering (BTE) is touted as a promising approach to promote bone tissue repair and regeneration. In this realm, development of collagen-based scaffolds incorporated with a bioceramic is often attempted to generate tissue scaffolds that resemble the organic and inorganic composition of native bone. In addition, a variety of different collagen processing techniques have been employed to produce anisotropically aligned scaffolds that can provide the essential biochemical and structural cues to guide cell response. While there have been numerous studies on …

The Relationship Between Biofouling Adhesion And Frequency Of Mechanical Cleaning To Control The Recruitment To Clear Coatings, Dylan Thomas Eggers

Theses and Dissertations

There is a need to control biofouling on sensors and transparent windows in the marine environment. Clear silicone coatings offer a method to reduce the adhesion strength of marine organisms to the surface, however, these also require mechanical cleaning to maintain the surfaces free of fouling. This research evaluated the performance of eighty seven formulations and took the top two candidates to investigate a) the frequencies of wiping required by a brush to maintain two coatings and uncoated glass surfaces free of fouling and b) the effects of clear silicone coatings fouling release properties on required frequencies. The panels were …

Steroid Receptor Coactivator-2 Drives Epithelial Reprogramming That Enables Murine Embryo Implantation, Vineet K Maurya, Maria M Szwarc, David M Lonard, Ramakrishna Kommagani, San Pin Wu, Bert W O'Malley, Francesco J Demayo, John P Lydon

Faculty, Staff and Students Publications

Although we have shown that steroid receptor coactivator-2 (SRC-2), a member of the p160/SRC family of transcriptional coregulators, is essential for decidualization of both human and murine endometrial stromal cells, SRC-2’s role in the earlier stages of the implantation process have not been adequately addressed. Using a conditional SRC-2 knockout mouse (SRC-2 ^d/d) in timed natural pregnancy studies, we show that endometrial SRC-2 is required for embryo attachment and adherence to the luminal epithelium. Implantation failure is associated with the persistent expression of Mucin 1 and E-cadherin on the apical surface and basolateral adherens junctions of the SRC-2 …