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Assessing Immediate Emotions In The Theory Of Planned Behavior Can Substantially Contribute To Increases In Pro-Environmental Behavior, Vanessa C. Ho, Anne H. Berman, Jackie Andrade, David J. Kavanagh, Stéphane La Branche, Jon May, Conner S. Philson, Daniel T. Blumstein Mar 2024

Assessing Immediate Emotions In The Theory Of Planned Behavior Can Substantially Contribute To Increases In Pro-Environmental Behavior, Vanessa C. Ho, Anne H. Berman, Jackie Andrade, David J. Kavanagh, Stéphane La Branche, Jon May, Conner S. Philson, Daniel T. Blumstein

School of Psychology

The Theory of Planned Behavior (TPB) is a highly influential and powerful behavior change model that offers promising guidance on promoting urgently needed, pro-environmental action. Recent pro-environmental research has successfully augmented TPB using anticipated emotions—the emotions an individual consciously predicts they will experience in relation to possible outcomes of their decision. However, immediate emotions—the emotions an individual actually experiences during decision-making—have received far less attention. Given that immediate emotions are relevant to pro-environmental decision-making and can address the theoretical and empirical limitations of TPB, we contend that pro-environmental studies should explicitly examine immediate emotions within the TPB framework. This article …


Anti-Phishing Approach For Iot System In Fog Networks Based On Machine Learning Algorithms, Mahmoud Gad Awwad, Mohamed M. Ashour, El Said A. Marzouk, Eman Abdelhalim Mar 2024

Anti-Phishing Approach For Iot System In Fog Networks Based On Machine Learning Algorithms, Mahmoud Gad Awwad, Mohamed M. Ashour, El Said A. Marzouk, Eman Abdelhalim

Mansoura Engineering Journal

As the Internet of Things (IoT) continues to expand, ensuring the security and privacyِ of IoT systems becomes increasingly critical. Phishing attacks pose a significant threat to IoT devices and can lead to unauthorized access, data breaches, and compromised functionality. In this paper, we propose an anti-phishing approach for IoT systems in fog networks that leverages machine learning algorithms, including a .fusion with deep learning techniques We explore the effectiveness of eleven traditional machine learning algorithms combined with deep learning in detecting and preventing phishing attacks in IoT systems. By utilizing a diverse range of algorithms, we aim to enhance …


The 50 Year History Of Collective Bargaining At Hofstra University, Herman A. Berliner, Peter C. Daniel, Bernard J. Firestone, Estelle S. Gellman, Elizabeth J. Ploran, Liora P. Schmelkin Mar 2024

The 50 Year History Of Collective Bargaining At Hofstra University, Herman A. Berliner, Peter C. Daniel, Bernard J. Firestone, Estelle S. Gellman, Elizabeth J. Ploran, Liora P. Schmelkin

Journal of Collective Bargaining in the Academy

The timeline of collective bargaining at Hofstra mirrors the timeline of the 50 National Center annual conferences. And the details of the Hofstra timeline, from organizing, to bargaining, from global issues to procedural details, from a bitter strike to collegiality, in an environment that respects both collective bargaining and shared governance, in a world without and then with COVID, provide a microcosm of the collective bargaining world over the decades. This article will start at the beginning of collective bargaining at Hofstra, reflect on social and economic changes during these 50 years, view the changing University aspirations, assess the impact …


The Persistence Of Separate And Unequal: Debunking Myths Of The Market In Bargaining For Faculty Gender Salary Equity, Johanna E. Foster, Jen Mcgovern Mar 2024

The Persistence Of Separate And Unequal: Debunking Myths Of The Market In Bargaining For Faculty Gender Salary Equity, Johanna E. Foster, Jen Mcgovern

Journal of Collective Bargaining in the Academy

The Persistence of Separate and Unequal:

Debunking Myths of the Market in Bargaining for Faculty Gender Salary Equity

ABSTRACT

For over a century, feminists have challenged occupational gender segregation as a mechanism to rationalize the devaluing of work assigned to women. The social movement momentum in the second half of the twentieth century helped narrow gender pay gaps both within and across occupations. Recently, apologists for gender discrimination have gained ground in obfuscating the role of gender segregation in reproducing salary inequity, pointing to a black box of “market forces” that presumably account for the devaluing of feminized fields, inside …


A Delphi Study To Explore Successful Implementation Of The International Baccalaureate Primary Years Programme From A Principal's Perspective, Hilary Reynolds Mar 2024

A Delphi Study To Explore Successful Implementation Of The International Baccalaureate Primary Years Programme From A Principal's Perspective, Hilary Reynolds

Dissertations

Purpose: The purpose of this Delphi study was to identify the essential elements needed to implement the International Baccalaureate Primary Years Programme (IB PYP) standards and practices from the perspective of elementary school principals who have successfully implemented the programme.

Methodology: This research study examined the essential elements needed for elementary schools as they transition to an IB PYP. This study illustrated the framework for the implementation of the study. Additionally, a description of the population, target population, and the sample used for the study was explored. The instrumentation, data collection procedures, and description of data analysis were then explained. …


Committee On Academic Standing Minutes March 13, 2024, Bronx Community College Committee On Academic Standing Mar 2024

Committee On Academic Standing Minutes March 13, 2024, Bronx Community College Committee On Academic Standing

BCC Governance Archives

Minutes for the meeting of the Committee on Academic Standing on March 13, 2024


The Role Of Age, Sex, And Mglur5 Receptors In Hippocampal Depotentiation In Mice, Michael Dew Mar 2024

The Role Of Age, Sex, And Mglur5 Receptors In Hippocampal Depotentiation In Mice, Michael Dew

Undergraduate Honors Theses

Synaptic plasticity of excitatory hippocampal circuits is one of the primary cellular mechanisms of learning and memory. Synaptic plasticity is also implicated in many disease states such as depression, post-traumatic stress disorder, and Alzheimer disease. Long-term potentiation (LTP) is the plastic strengthening of synapses, while long-term depression (LTD) is the weakening of synapses. Depotentiation is the process of reversing previously established long-term potentiation. Depotentiation has not been studied as thoroughly as long-term potentiation and long-term depression. We examined the role of age, metabotropic glutamate receptor 5 (mGluR5), and sex in the process of CA1 hippocampal depotentiation in young CD-1 mice …


Rapid Discovery Of House-Keeping Genes In The Bacterium Kushneria, Using A Slalom-Library-Based Crispri Forward Genetic Screen, Andrew Jenkins Mar 2024

Rapid Discovery Of House-Keeping Genes In The Bacterium Kushneria, Using A Slalom-Library-Based Crispri Forward Genetic Screen, Andrew Jenkins

Undergraduate Honors Theses

Rising soil salinity levels worldwide have resulted in the loss of millions of hectares of viable cropland. Several solutions to this problem have been posited, including looking into the properties of salt-tolerant plants. Recent research into salttolerant plants in southern Utah has found a host of microorganisms isolated from the soil, plant surfaces, or plant tissues that stimulate salt tolerance in alfalfa. Leveraging a Mobile-CRISPRi system to repress a library of genes created through the recently developed sgRNA Library Assembly by Ligation onto Magnetic Beads (SLALOM) protocol, we induced genome-wide repression of genes in Kushneria spp. grown under optimal and …


Recent Progress On Gene-Deleted Liveattenuated African Swine Fever Virus Vaccines, Hiep L.X. Vu, David Scott Mcvey Mar 2024

Recent Progress On Gene-Deleted Liveattenuated African Swine Fever Virus Vaccines, Hiep L.X. Vu, David Scott Mcvey

Department of Animal Science: Faculty Publications

African Swine Fever (ASF) is a highly lethal viral disease in swine, with mortality rates approaching 100%. The disease has spread to many swine-producing countries, leading to significant economic losses and adversely impacting global food security. Extensive efforts have been directed toward developing effective ASF vaccines. Among the vaccinology approaches tested to date, liveattenuated virus (LAV) vaccines produced by rational deleting virulence genes from virulent African Swine Fever Virus (ASFV) strains have demonstrated promising safety and efficacy in experimental and field conditions. Many gene-deleted LAV vaccine candidates have been generated in recent years. The virulence genes targeted for deletion from …


Recent Progress On Gene-Deleted Liveattenuated African Swine Fever Virus Vaccines, Hiep Vu, David Scott Mcvey Mar 2024

Recent Progress On Gene-Deleted Liveattenuated African Swine Fever Virus Vaccines, Hiep Vu, David Scott Mcvey

Department of Animal Science: Faculty Publications

African Swine Fever (ASF) is a highly lethal viral disease in swine, with mortality rates approaching 100%. The disease has spread to many swine-producing countries, leading to significant economic losses and adversely impacting global food security. Extensive efforts have been directed toward developing effective ASF vaccines. Among the vaccinology approaches tested to date, liveattenuated virus (LAV) vaccines produced by rational deleting virulence genes from virulent African Swine Fever Virus (ASFV) strains have demonstrated promising safety and efficacy in experimental and field conditions. Many gene-deleted LAV vaccine candidates have been generated in recent years. The virulence genes targeted for deletion from …


Roles Of Bryophytes In Forest Sustainability—Positive Or Negative?, Janice M. Glime Mar 2024

Roles Of Bryophytes In Forest Sustainability—Positive Or Negative?, Janice M. Glime

Michigan Tech Publications

Bryophytes were traditionally ignored in most studies of forest ecosystem processes, or they were included with litter or soil. In the last few decades we have begun to understand their many roles that permit them to be ecosystem engineers. This review serves to pull together many scattered sources into a single source on the many contributions bryophytes can perform as ecosystem engineers and to support what several authors have already stressed: that bryophytes should not be treated as a single functional group. It puts bryophytes in perspective in terms of richness and biomass, then explores their roles as ecosystem engineers; …


March 13, 2024 Faculty Senate Minutes, University Of South Carolina Mar 2024

March 13, 2024 Faculty Senate Minutes, University Of South Carolina

Faculty Senate

No abstract provided.


Resolving The Nanoscale Structure Of Β-Sheet Peptide Self-Assemblies Using Single-Molecule Orientation–Localization Microscopy, Weiyan Zhou, Conor L. O'Neill, Tianben Ding, Oumeng Zhang, Jai S. Rudra, Matthew D. Lew Mar 2024

Resolving The Nanoscale Structure Of Β-Sheet Peptide Self-Assemblies Using Single-Molecule Orientation–Localization Microscopy, Weiyan Zhou, Conor L. O'Neill, Tianben Ding, Oumeng Zhang, Jai S. Rudra, Matthew D. Lew

Electrical & Systems Engineering Publications and Presentations

Synthetic peptides that self-assemble into cross-β fibrils are versatile building blocks for engineered biomaterials due to their modularity and biocompatibility, but their structural and morphological similarities to amyloid species have been a long-standing concern for their translation. Further, their polymorphs are difficult to characterize using spectroscopic and imaging techniques that rely on ensemble averaging to achieve high resolution. Here, we utilize Nile red (NR), an amyloidophilic fluorogenic probe, and single-molecule orientation-localization microscopy (SMOLM) to characterize fibrils formed by the designed amphipathic enantiomers KFE8L and KFE8D and the pathological amyloid-beta peptide Aβ42. Importantly, NR SMOLM reveals the helical (bilayer) …


Identification Of A Novel Target For Declustering Supernumerary Centrosomes In Triple Negative Breast Cancer, Priyanga J Mar 2024

Identification Of A Novel Target For Declustering Supernumerary Centrosomes In Triple Negative Breast Cancer, Priyanga J

Theses and Dissertations

Triple-negative breast cancer (TNBC) confers considerable interventional challenge owing to its massive heterogeneity, aggression and metastatic prowess. These facets are attributed to chromosomal instability (CIN), a feature consequent to TNBC cell’s ability to harbor more than two centrosomes (supernumerary centrosomes; SNCs).

In principle, if a normal cell possesses SNCs, uneven pull forces are generated consequent to multipolar spindle, which activates cellular surveillance. This ensures error-free mitosis by either repairing the error or, in an irreparable condition, driving cells to death. This averts the possibility of aneuploidy (fundamental to tumorigenesis).

Unfortunately, TNBC cells, despite harboring SNCs, have devised a survival strategy …


Predicting Gender Of Author Using Large Language Models (Llms), Satya Uday Sanku Mar 2024

Predicting Gender Of Author Using Large Language Models (Llms), Satya Uday Sanku

USF Tampa Graduate Theses and Dissertations

The advent of text data from social media, blogs, movie reviews, and other textual sources has opened new avenues for research, particularly in the domain of Author Profiling. Author Profiling helps in Capturing the Stylistic features and also useful for analyzing the required elements in the written text. This Study addresses one of the tasks in Author Profiling which is termed as gender detection or Classification of Gender from Text. The main goal of this research is to obtain valuable and relevant gender characteristics that will accurately classify the Author’s gender of a review extracted from an Anime Review website. …


March 13, 2024 (Vol. 108, No. 23), Daily Eastern News Mar 2024

March 13, 2024 (Vol. 108, No. 23), Daily Eastern News

Daily Eastern News: 2023-2024

No abstract provided.


Β-Sheets Mediate The Conformational Change And Allosteric Signal Transmission Between The Aslov2 Termini, Sian Xiao, Mayar Terek Ibrahim, Gennady M. Verkhivker, Brian D. Zoltowski, Peng Tao Mar 2024

Β-Sheets Mediate The Conformational Change And Allosteric Signal Transmission Between The Aslov2 Termini, Sian Xiao, Mayar Terek Ibrahim, Gennady M. Verkhivker, Brian D. Zoltowski, Peng Tao

Mathematics, Physics, and Computer Science Faculty Articles and Research

Avena sativa phototropin 1 light-oxygen-voltage 2 domain (AsLOV2) is a model protein of Per-Arnt-Sim (PAS) superfamily, characterized by conformational changes in response to external environmental stimuli. This conformational change begins with the unfolding of the N-terminal A'α helix in the dark state followed by the unfolding of the C-terminal Jα helix. The light state is characterized by the unfolded termini and the subsequent modifications in hydrogen bond patterns. In this photoreceptor, β-sheets are identified as crucial components for mediating allosteric signal transmission between the two termini. Through combined experimental and computational investigations, the Hβ …


Increasing Multi-Hazard Climate Risk And Financial And Health Impacts On Northern Homeowners, Tobias Schwoerer, Jennifer I. Schmidt, Matthew Berman, Peter Bieniek, Louise M. Farquharson, Dmitry Nicolsky, James E. Powell, Rachel Roberts, Rick Thoman, Robert Ziel Mar 2024

Increasing Multi-Hazard Climate Risk And Financial And Health Impacts On Northern Homeowners, Tobias Schwoerer, Jennifer I. Schmidt, Matthew Berman, Peter Bieniek, Louise M. Farquharson, Dmitry Nicolsky, James E. Powell, Rachel Roberts, Rick Thoman, Robert Ziel

Faculty, Staff, and Students

Currently, more than half of the world’s human population lives in urban areas, which are increasingly affected by climate hazards. Little is known about how multi-hazard environments affect people, especially those living in urban areas in northern latitudes. This study surveyed homeowners in Anchorage and Fairbanks, USA, Alaska’s largest urban centers, to measure individual risk perceptions, mitigation response, and damages related to wildfire, surface ice hazards, and permafrost thaw. Up to one third of residents reported being affected by all three hazards, with surface ice hazards being the most widely distributed, related to an estimated $25 million in annual damages. …


Geography, Climate, And Habitat Shape The Microbiome Of The Endangered Rock Gnome Lichen (Cetradonia Linearis), Julianna Paulsen, Jessica L. Allen, Nathan Morris, Jenna Dorey, Jenifer B. Walke, S. Elizabeth Alter Mar 2024

Geography, Climate, And Habitat Shape The Microbiome Of The Endangered Rock Gnome Lichen (Cetradonia Linearis), Julianna Paulsen, Jessica L. Allen, Nathan Morris, Jenna Dorey, Jenifer B. Walke, S. Elizabeth Alter

Biology, Agriculture and Chemistry Faculty Publications and Presentations

Bacterial symbionts are essential components of healthy biological systems. They are increasingly recognized as important factors in the study and management of threatened species and ecosystems. Despite management shifts at the ecosystem level, microbial communities are often neglected in discussions of holobiont conservation in favor of the primary members of a symbiosis. In this study, we addressed the bacterial community knowledge gap for one of two federally endangered lichen species in the United States, Cetradonia linearis (Cladoniaceae). We collected 28 samples of the endangered rock gnome lichen (Cetradonia linearis) from 13 sites and characterized bacterial communities in thalli using 16S …


Dysregulated Creb3 Cleavage At The Nuclear Membrane Induces Karyoptosis-Mediated Cell Death, Ga-Eun Lee, Geul Bang, Jiin Byun, Cheol-Jung Lee, Weidong Chen, Dohyun Jeung, Hyun-Jung An, Han Chang Kang, Dae Joon Kim, Megan Keniry Mar 2024

Dysregulated Creb3 Cleavage At The Nuclear Membrane Induces Karyoptosis-Mediated Cell Death, Ga-Eun Lee, Geul Bang, Jiin Byun, Cheol-Jung Lee, Weidong Chen, Dohyun Jeung, Hyun-Jung An, Han Chang Kang, Dae Joon Kim, Megan Keniry

School of Medicine Publications

Cancer cells often exhibit resistance to apoptotic cell death, but they may be vulnerable to other types of cell death. Elucidating additional mechanisms that govern cancer cell death is crucial for developing new therapies. Our research identified cyclic AMP-responsive element-binding protein 3 (CREB3) as a crucial regulator and initiator of a unique cell death mechanism known as karyoptosis. This process is characterized by nuclear shrinkage, deformation, and the loss of nuclear components following nuclear membrane rupture. We found that the N-terminal domain (aa 1-230) of full-length CREB3 (CREB3-FL), which is anchored to the nuclear inner membrane (INM), interacts with lamins …


Synthesis And Functional Properties Of Metal Chalcogenide Semiconductors, Jiang Luo Mar 2024

Synthesis And Functional Properties Of Metal Chalcogenide Semiconductors, Jiang Luo

Arts & Sciences Graduate Student Theses and Dissertations

Metal chalcogenides exhibit perovskite, chiral, and layered structures, and accommodate many atoms from periodic table, providing abundant properties such as ferroelectricity, circular dichroism, and anisotropic carrier transport. Those various physical properties make metal chalcogenides promising for the applications from electronics to optoelectronics, such as thermoelectrics, photovoltaics, and photodetectors. The upper limit of carrier mobility, termed as intrinsic carrier mobility, is the key factor that determine the performance of the semiconductor-based applications. However, either experiments or first-principle calculations are challenging to obtain the intrinsic carrier mobility over a wide class of materials. I found a descriptor that have a good correlation …


An Exposome Atlas Of Serum Reveals The Risk Of Chronic Diseases In The Chinese Population, Lei You, Jing Kou, Mengdie Wang, Guoqin Ji, Xiang Li, Chang Su, Fujian Zheng, Mingye Zhang, Yuting Wang, Tiantian Chen, Ting Li, Lina Zhou, Xianzhe Shi, Chunxia Zhao, Xinyu Liu, Surong Mei, Guowang Xu Mar 2024

An Exposome Atlas Of Serum Reveals The Risk Of Chronic Diseases In The Chinese Population, Lei You, Jing Kou, Mengdie Wang, Guoqin Ji, Xiang Li, Chang Su, Fujian Zheng, Mingye Zhang, Yuting Wang, Tiantian Chen, Ting Li, Lina Zhou, Xianzhe Shi, Chunxia Zhao, Xinyu Liu, Surong Mei, Guowang Xu

Faculty, Staff and Student Publications

Although adverse environmental exposures are considered a major cause of chronic diseases, current studies provide limited information on real-world chemical exposures and related risks. For this study, we collected serum samples from 5696 healthy people and patients, including those with 12 chronic diseases, in China and completed serum biomonitoring including 267 chemicals via gas and liquid chromatography-tandem mass spectrometry. Seventy-four highly frequently detected exposures were used for exposure characterization and risk analysis. The results show that region is the most critical factor influencing human exposure levels, followed by age. Organochlorine pesticides and perfluoroalkyl substances are associated with multiple chronic diseases, …


Genomic Evolution Shapes Prostate Cancer Disease Type, Dan J Woodcock, Atef Sahli, Ruxandra Teslo, Vinayak Bhandari, Andreas J Gruber, Aleksandra Ziubroniewicz, Gunes Gundem, Yaobo Xu, Adam Butler, Ezequiel Anokian, Bernard J Pope, Chol-Hee Jung, Maxime Tarabichi, Stefan C Dentro, J Henry R Farmery, Cruk Icgc Prostate Group, Peter Van Loo, Anne Y Warren, Vincent Gnanapragasam, Freddie C Hamdy, G Steven Bova, Christopher S Foster, David E Neal, Yong-Jie Lu, Zsofia Kote-Jarai, Michael Fraser, Robert G Bristow, Paul C Boutros, Anthony J Costello, Niall M Corcoran, Christopher M Hovens, Charlie E Massie, Andy G Lynch, Daniel S Brewer, Rosalind A Eeles, Colin S Cooper, David C Wedge Mar 2024

Genomic Evolution Shapes Prostate Cancer Disease Type, Dan J Woodcock, Atef Sahli, Ruxandra Teslo, Vinayak Bhandari, Andreas J Gruber, Aleksandra Ziubroniewicz, Gunes Gundem, Yaobo Xu, Adam Butler, Ezequiel Anokian, Bernard J Pope, Chol-Hee Jung, Maxime Tarabichi, Stefan C Dentro, J Henry R Farmery, Cruk Icgc Prostate Group, Peter Van Loo, Anne Y Warren, Vincent Gnanapragasam, Freddie C Hamdy, G Steven Bova, Christopher S Foster, David E Neal, Yong-Jie Lu, Zsofia Kote-Jarai, Michael Fraser, Robert G Bristow, Paul C Boutros, Anthony J Costello, Niall M Corcoran, Christopher M Hovens, Charlie E Massie, Andy G Lynch, Daniel S Brewer, Rosalind A Eeles, Colin S Cooper, David C Wedge

Faculty, Staff and Student Publications

The development of cancer is an evolutionary process involving the sequential acquisition of genetic alterations that disrupt normal biological processes, enabling tumor cells to rapidly proliferate and eventually invade and metastasize to other tissues. We investigated the genomic evolution of prostate cancer through the application of three separate classification methods, each designed to investigate a different aspect of tumor evolution. Integrating the results revealed the existence of two distinct types of prostate cancer that arise from divergent evolutionary trajectories, designated as the Canonical and Alternative evolutionary disease types. We therefore propose the evotype model for prostate cancer evolution wherein Alternative-evotype …


Viral Epitope Scanning Reveals Correlation Between Seasonal Hcovs And Sars-Cov-2 Antibody Responses Among Cancer And Non-Cancer Patients, Salum J. Lidenge, Dicle Yalcin, Sydney J. Bennett, Owen Ngalamika, Brenda B. Kweyamba, Chacha J. Mwita, For Yue Tso, Julius Mwaiselage, John T. West, Charles Wood Mar 2024

Viral Epitope Scanning Reveals Correlation Between Seasonal Hcovs And Sars-Cov-2 Antibody Responses Among Cancer And Non-Cancer Patients, Salum J. Lidenge, Dicle Yalcin, Sydney J. Bennett, Owen Ngalamika, Brenda B. Kweyamba, Chacha J. Mwita, For Yue Tso, Julius Mwaiselage, John T. West, Charles Wood

School of Biological Sciences: Faculty Publications

Seasonal coronaviruses (HCoVs) are known to contribute to cross-reactive antibody (Ab) responses against SARS-CoV-2. While these responses are predictable due to the high homology between SARS-CoV-2 and other CoVs, the impact of these responses on susceptibility to SARS-CoV-2 infection in cancer patients is unclear. To investigate the influence of prior HCoV infection on anti- SARS-CoV-2 Ab responses among COVID-19 asymptomatic individuals with cancer and controls without cancers, we utilized the VirScan technology in which phage immunoprecipitation and sequencing (PhIP-seq) of longitudinal plasma samples was performed to investigate high-resolution (i.e., epitope level) humoral CoV responses. Despite testing positive for anti-SARS-CoV-2 Ab …


Facile Synthesis Of Fe2o3, Fe2o3@ Cuo And Wo3 Nanoparticles: Characterization, Structure Determination And Evaluation Of Their Biological Activity, Asmaa Taha Mar 2024

Facile Synthesis Of Fe2o3, Fe2o3@ Cuo And Wo3 Nanoparticles: Characterization, Structure Determination And Evaluation Of Their Biological Activity, Asmaa Taha

Nanotechnology Research Centre

Due to their high specific surface area and its characteristic’s functionalized nanomaterials have great potential in medical applications specialty, as an anticancer. Herein, functional nanoparticles (NPs) based on iron oxide Fe2O3, iron oxide modified with copper oxide Fe2O3@ CuO, and tungsten oxide WO3 were facile synthesized for biomedical applications. The obtained nanomaterials have nanocrystal sizes of 35.5 nm for Fe2O3, 7 nm for Fe2O3@ CuO, and 25.5 nm for WO3. In addition to octahedral and square nanoplates for Fe2O3, and WO3; respectively. Results revealed that Fe2O3, Fe2O3@ CuO, and WO3 NPs showed remarked anticancer effects versus a safe effect on …


Bioaccumulation Of Сr, Zn, Pb And Cu In Ambrosia Artemisiifolia L. And Erigeron Canadensis L., Volodymyr Laptiev, Samuel Obeng Apori, Michelle Giltrap, Furong Tian, Nataliia Ryzhenko Mar 2024

Bioaccumulation Of Сr, Zn, Pb And Cu In Ambrosia Artemisiifolia L. And Erigeron Canadensis L., Volodymyr Laptiev, Samuel Obeng Apori, Michelle Giltrap, Furong Tian, Nataliia Ryzhenko

Articles

The city of Dnipro, a prominent industrial hub in Ukraine, is recognized for its particularly its significant industrial development. This study focused on two prevalent plant species, Ambrosia artemisiifolia L. and Erigeron canadensis L., within the vicinity. Sampling was conducted at points located 12.02 km away from the emission sources associated with battery production and recycling plants in Dnipro. Analysis of heavy metal concentrations such as, Cr, Cu, Pb, and Zn was conducted using atomic emission spectrometry from the soil and plants tissues of Ambrosia artemisiifolia L. and Erigeron canadensis L. The translocation coefficient (TF) was calculated for both plant …


Modified Folfox6 Plus Bevacizumab With And Without Nivolumab For First-Line Treatment Of Metastatic Colorectal Cancer: Phase 2 Results From The Checkmate 9x8 Randomized Clinical Trial, Antonio Ucar Mar 2024

Modified Folfox6 Plus Bevacizumab With And Without Nivolumab For First-Line Treatment Of Metastatic Colorectal Cancer: Phase 2 Results From The Checkmate 9x8 Randomized Clinical Trial, Antonio Ucar

All Publications

Background: Standard first-line therapies for metastatic colorectal cancer (mCRC) include fluoropyrimidine-containing regimens with oxaliplatin and/or irinotecan and a biologic agent. Immunotherapy may enhance antitumor activity in combination with standard therapies in patients with mCRC. Here, we present phase 2 results of nivolumab plus standard-of-care therapy (SOC; 5-fluorouracil/leucovorin/oxaliplatin/bevacizumab) versus SOC in the first-line treatment of patients with mCRC (CheckMate 9X8).

Methods: CheckMate 9X8 was a multicenter, open-label, randomized, phase 2/3 trial. Eligible patients were at least 18 years of age with unresectable mCRC and no prior chemotherapy for metastatic disease. Patients were randomized 2:1 to receive nivolumab 240 mg plus SOC …


Health Status In An Urban-Dwelling, Subtropical Frog Species (Lithobates Sphenocephalus) And Its Relation To Ranavirus And Hemoparasites, Gabrielle M. Wickersham Mar 2024

Health Status In An Urban-Dwelling, Subtropical Frog Species (Lithobates Sphenocephalus) And Its Relation To Ranavirus And Hemoparasites, Gabrielle M. Wickersham

USF Tampa Graduate Theses and Dissertations

Urbanization poses significant challenges to wildlife, including amphibians. The present study uses a multi-parameter approach that incorporates veterinary techniques to investigate the current health status of the adult southern leopard frogs (Lithobates sphenocephalus) in Tampa Bay, Florida, amidst urban stressors including nutrient loading, fragmented habitats, and light and noise pollution. Novel values for fluctuating asymmetry (e.g., variation between left and right bilateral traits; FA), body condition (CF), stress (e.g., neutrophil:lymphocyte (N:L) ratio), and inflammation (e.g., neutrophil morphologic abnormalities, parasite load) are reported. I also investigate the relationship of overall health with ranavirus presence and hemoparasite infections. Ranavirus was absent in …


Microcurrent-Mediated Modulation Of Myofibroblasts For Cardiac Repair And Regeneration, Dipthi Bachamanda Somesh, Karsten Jürchott, Thomas Giesel, Thomas Töllner, Alexander Prehn, Jan-Peter Richters, Dragana Kosevic, J. Eduardo Rame, Peter Göttel, Johannes Müller Mar 2024

Microcurrent-Mediated Modulation Of Myofibroblasts For Cardiac Repair And Regeneration, Dipthi Bachamanda Somesh, Karsten Jürchott, Thomas Giesel, Thomas Töllner, Alexander Prehn, Jan-Peter Richters, Dragana Kosevic, J. Eduardo Rame, Peter Göttel, Johannes Müller

Division of Cardiology Faculty Papers

Cardiovascular diseases are a significant cause of illness and death worldwide, often resulting in myofibroblast differentiation, pathological remodeling, and fibrosis, characterized by excessive extracellular matrix protein deposition. Treatment options for cardiac fibrosis that can effectively target myofibroblast activation and ECM deposition are limited, necessitating an unmet need for new therapeutic approaches. In recent years, microcurrent therapy has demonstrated promising therapeutic effects, showcasing its translational potential in cardiac care. This study therefore sought to investigate the effects of microcurrent therapy on cardiac myofibroblasts, aiming to unravel its potential as a treatment for cardiac fibrosis and heart failure. The experimental design involved …


Interrelationships Among Local Values Of Wet Bulb Globe Temperature, Heat Index, And Adjusted Temperature, Andrea Giraldo Mar 2024

Interrelationships Among Local Values Of Wet Bulb Globe Temperature, Heat Index, And Adjusted Temperature, Andrea Giraldo

USF Tampa Graduate Theses and Dissertations

Occupational heat stress significantly affects outdoor workers who face challenges due to increased heat exposure. Because of the prevalence of heat illness, it is important to measure heat stress for outdoor workers. Monitoring occupational heat stress most often relies on the Wet Bulb Globe Temperature (WBGT) measure. Heat Index (HI) is a widely used measure to account for air temperature and humidity. Adjusted Temperature (Tadj) considers air temperature, humidity and estimates radiant heat. There is interest in predicting WBGT from HI and HI from WBGT. This study builds on previous USF research by Bernard and Iheanacho and Irvin to evaluate …