Digital Commons Network^™

The Role Of Age And Biological Sex On Short-Term Memory In The Syrian Hamster (Mesocricetus Auratus), Laura E. Garcia, Mario Gil

Research Symposium

Background: Aging plays an important role in cognitive function, memory, and mental health. As we age, some cognitive functions become weaker. Aging is also a critical risk factor for dementia and Alzheimer’s Disease. With recent advances seen in public health, humans are living longer years. This makes it a challenge to make those added years healthy. For this reason, it is important to continue studying its effects by using, the Syrian hamster, as a model. The purpose of the study is to identify other factors that might also have a role in short-term memory, besides aging.

Methods: All behavioral …

The Reality Of Psychological Preparation Among Jordanian National Teams For Individual Sports During The Coronavirus Outbreak, Ayed Zureigat, Osama Abdel Fattah

Jordan Journal of Applied Science-Humanities Series

This study aimed to identify the reality of psychological preparation among players of the Jordanian national teams for individual sports during the Coronavirus outbreak. Additionally, it sought to assess the levels of depression and anxiety among these players during the same period. To achieve this, a descriptive method was employed with a sample consisting of 54 participants. To minimize face-to-face interaction, an electronic questionnaire was created using Google Forms, containing 28 items addressing depression, anxiety, and psychological methods used with players. Of these items, 12 were related to depression and anxiety, while 16 were focused on psychological methods. To analyze …

Medical School Watercooler Newsletter - March 24, 2024, Lindsey Lyle

Watercooler Newsletter

This is the March 24, 2024 edition of the Frederick P. Whiddon College of Medicine’s newsletter - Watercooler.

Contents Include

• ODI Staff to discuss health disparities and equities
• Whiddon College of Medicine welcomes new associate dean for finance and administration
• Special OB-GYN grand rounds to focus on Black maternal mortality
• Meet a Med Student: Kramer Crider
• USA investigators identify potential biomarker for early pancreatic cancer diagnosis
• The Final Countdown: Doc Rock is Thursday Night
• DiPalma honored at 19th Annual Distinguished Alumni & Service Awards

The Chronicle, Kennedy Ballinger, Lara Jones, Dashae Engler, Bella Perez, Emily Riley, Riley Dickerson, Maya Pierce, Andy Langager

Campus Chronicle

No abstract provided.

Faculty Senate Meeting Agenda And Minutes, March 24, 2024

Faculty Senate Minutes and Agendas

Agenda and minutes from the Wright State University Faculty Senate Meeting held on, March 24, 2024.

Efficient Removal Of Chemical Organic Demand And Total Organic Carbon From Leachate Using Heterogeneous Fenton Catalyst Based On Activated Carbon, Amar Idir, Mounir Ziati, Mohamed Bouzid

Emirates Journal for Engineering Research

Organic components contained in leachates resulting from decomposition of waste are difficult to degrade. Leachate volume and its composition vary depending on biogeochemistry of site type of deposited residues, and the age of sanitary landfill. The present study aims to develop efficient heterogeneous Fenton oxidation of organic matter, expressed in terms of chemical organic demand (COD) and total organic carbon (TOC) of leachate using the newly synthesized iron-modified activated carbon. The characterization of catalyst revealed that the Fe(II) was successfully introduced onto the original activated carbon (AC) and diversified the material’s surface morphology and elemental compounds. The heterogeneous Fenton oxidation …

The Invasive Bank Vole (Clethrionomys Glareolus); A Longitudinal Investigation Into Rodents And Their Pathogen Communities, Using The Irish Rodent Invasion As A Model System., Andrew Mcmanus

Theses

The recent emergence of zoonotic pathogens such as, SARS-CoV-2, Ebola and Mpox, have emphasised the necessity to study wildlife and their pathogens. A knowledge gap currently exists in longitudinal studies of biological invasions, which are needed to understand the change in pathogen communities caused as the invader becomes more established. The invasion of Clethrionomys glareolus in Ireland provides a unique model system to study these changes at different stages of the bio-invasion. This is due to the depauperate small mammal community in Ireland, identifiable source population, introduction point, and ongoing expansion of C. glareolus in Ireland. Extensive work has been …

Promoting Faculty Research Excellence And Visibility In Nigerian Universities Through The Open Access Paradigm Shift, Colette Ogugua Onyebinama Dr., Ngozi Chima-James Dr.

Library Philosophy and Practice (e-journal)

The primary objective of this article is to promote faculty research excellence and visibility in Nigerian universities through open access publishing. The article begins by briefly discussing the vital role that universities play in research, which is a fundamental duty of faculty members. The study provides a succinct definition of research excellence and visibility, as well as the methods for assessing research excellence. This leads to a brief discussion on promoting faculty research visibility through publication on open access platforms such as open access journals and open access institutional repositories to increase citations rates and enhance visibility. The paper further …

Advancing Primary Ciliary Dyskinesia Diagnosis Through High-Speed Video Microscopy Analysis, Wilfredo De Jesús-Rojas, Zachary J Demetriou, José Muñiz-Hernández, Gabriel Rosario-Ortiz, Frances M Quiñones, Marcos J Ramos-Benitez, Ricardo A Mosquera

Faculty, Staff and Student Publications

Primary ciliary dyskinesia (PCD) is an inherited disorder that impairs motile cilia, essential for respiratory health, with a reported prevalence of 1 in 16,309 within Hispanic populations. Despite 70% of Puerto Rican patients having the RSPH4A [c.921+3_921+6del (intronic)] founder mutation, the characterization of the ciliary dysfunction remains unidentified due to the unavailability of advanced diagnostic modalities like High-Speed Video Microscopy Analysis (HSVA). Our study implemented HSVA for the first time on the island as a tool to better diagnose and characterize the RSPH4A [c.921+3_921+6del (intronic)] founder mutation in Puerto Rican patients. By applying HSVA, we analyzed the ciliary beat frequency …

[Discussions] Vol. 19 Iss. 1

Discussions

This issue of Discussions was published for the Spring 2023 cycle.

Targeting Mycobacterial Efflux System For Combating Anti-Microbial Resistance, Arathi Radhakrishnan, Raj Kishor Kapardar, Rajpal Srivastav

Research Symposium

Background: The drug resistance in the microbes is a serious concern in medicine. Along with intrinsic factors, extrinsic factors like unprescribed usage of drugs are the contributing factors. The drug tolerance has led to the emergence of superbugs. Mycobacterial species utilize an array of multidrug efflux mechanisms linked to intrinsic and acquired antibiotic resistance. Understanding molecular mechanisms regulating efflux could reveal new therapeutic targets and strategies. Our study is aimed to target regulators of efflux Mycobacterial transporter.

Methods: Using the reference mycobacterial strain, antibiotic sensitivity was first profiled by minimal inhibitory concentration assays across a panel of antimicrobials, followed by …

Proteomic Analysis Of Stress Associated Factor Overexpression In Hepatocellular Carcinoma, Mohammad Shabir Hussain, Sophia Leslie, Amayrani Sanchez, Samantha Lopez, Kyle Doxtater, Manish Kumar Tripathi

Research Symposium

Background: Hepatocellular carcinoma (HCC) constitutes a substantial portion, accounting for 85% to 90% of liver cancers worldwide. Notably, within the Hispanic population, liver cancer mortality rates are notably higher, particularly evident in regions like the South Texas Rio Grande Valley (RGV), where nearly 90% of the populace is Latino/Hispanic. This region grapples with poverty affecting nearly 30% of its residents, coupled with elevated rates of obesity, diabetes, and low-income households, thereby fostering a prevalent environment of stress. Stress can profoundly impact cancer outcomes by compromising immune functionality and triggering inflammatory responses, potentially impairing surveillance against oncogenic triggers. The activation of …

Piperlongumine Nanoformulation Attenuates Pancreatic Tumor Desmoplasia And Alter Tumor Immune Responses, Vivek Kumar Kashyap, Neeraj Chauhan, Mohammed Sikander, Eswara N. H. K. Ghali, Bilal Hafeez, Murali M. Yallapu, Meena Jaggi, Subhash C. Chauhan

Research Symposium

Pancreatic cancer (PanCa) is characterized by lack of early diagnosis, poor response to available therapeutic modalities and chemoresistance. Gemcitabine (GEM) is currently considered the most effective therapy for PanCa; however, it shows only a marginal survival benefit of 6 months. This poor drug response has been attributed to desmoplasia, causes suboptimal drug delivery, alters tumor microenvironment (TME), which includes tumor surrounding blood vessels, fibroblasts, immune cells, extracellular matrix, and other signaling molecules and induces chemo-resistance in tumors. To overcome these existing issues associated with chemotherapy, identification and development of novel therapeutic modalities are a pressing need. Piperlongumine (PL) is a …

The Role Of Long Noncoding Rnas In Ocular Angiogenesis And Vascular Oculopathy, Pranali Gandhi, Yuzhi Wang, Guigang Li, Shusheng Wang

School of Medicine Faculty Publications

Background: Long noncoding RNAs (lncRNAs) are RNA transcripts over 200 nucleotides in length that do not code for proteins. Initially considered a genomic mystery, an increasing number of lncRNAs have been shown to have vital roles in physiological and pathological conditions by regulating gene expression through diverse mechanisms depending on their subcellular localization. Dysregulated angiogenesis is responsible for various vascular oculopathies, including diabetic retinopathy, retinopathy of prematurity, age-related macular degeneration, and corneal neovascularization. While anti-VEGF treatment is available, it is not curative, and long-term outcomes are suboptimal, and some patients are unresponsive. Results and summary: To better understand these diseases, …

Branz, Stephen, San Jose State University

Emeritus and Retired Faculty Biographies

Massachusetts Institute of Technology, Organic Chemistry, 1978 Ph.D.

Brandeis University, Chemistry, 1973 B.A

Syntex Corporation, Postdoctoral Research, 1980-1981

University College (London), Postdoctoral Research / Temporary Lecturer, 1978-80

Juvenile Delinquency As A Contemporary Issue In Nigeria: Understanding The Impacts Of Parenting Styles, Single Parenting, And Marital Discord, Sunkanmi Folorunsho, Oluwakemi Abdulrazaq, Victor Ajayi

Department of Sociology: Dissertations, Theses, and Student Research

When addressing juvenile delinquencies in Nigeria, it is important to consider the roles and effects of parenting styles and family structures. Although, there are no universally accepted parenting styles, evidence and studies have pointed to some parenting styles that expose children to delinquent behaviors. We examined different parenting styles comprehensively in this article and how these styles can influence juvenile delinquencies. We also discussed the association between single-parenting and behavioral outcomes; accounting how single-parenting may increase risks of delinquencies. Furthermore, marital discord was discussed and social learning theory by Albert Bandura was adopted to buttress our positions. We concluded that …

Session Iiic: Biology - An In-Vitro Study Of The Antimicrobial Effects Of Essential Oils On Human Skin Microbiota (Undergraduate), Marissa Dimatteo, Katie Wilson, Aedan Kerr

Life of the Scholar Multidisciplinary Conference

No abstract provided.

Session Ia: Biology Presentation 1 - He Shows Seashells By The Cambridgeshire: Presenting At Bivalves: Where Are We Going (Undergraduate), Timothy D. Campbell

Life of the Scholar Multidisciplinary Conference

A description of my opportunity to attend an international bivalve meeting and the research that I presented at it.

Session Ia: Biology Presentation 2 - Food Allergies And The Immune Response: Milk, Egg, And Shellfish Allergies (Undergraduate), Marissa Dimatteo

Life of the Scholar Multidisciplinary Conference

There has been an increased prevalence of food allergies within the last decade with very little information on preventative measures and treatments. They can have long lasting and life threatening consequences with a wide range of symptoms. Egg and milk allergy are most common in children whereas shellfish is most common in adults. Early introduction and immunotherapy have been recommended to desensitize the immune system.

Knyaw/Karen Womanhood, Generational Healing And The Interplay Of Faith, Genocide, Gender Roles, And Education In The Face Of Health Diagnosis, Moo Law Eh Soe

UNO Student Research and Creative Activity Fair

During the fall semester of 2023, my honors project aimed to provide representation and shed light on the challenges Knyaw/Karen women encounter as part of their womanhood in traditional and Western communities. The issues are emphasized when these women receive life-altering health diagnosis that not only alters their identities but also requires them to step beyond the invisible parameters of what it means to be a Knyaw/Karen woman. It's worth noting that all the women I interviewed were immigrants from the Thai-Burma Border refugee Camps where Indigenous Knyaw people have been facing at least 70 years of genocide. The project …

Exploring The Role Of Calcineurin In Filamentation Across Inducing Conditions In The Fungal Pathogen Candida Albicans, Patricia Harte-Maxwell, Jill R. Blankenship

UNO Student Research and Creative Activity Fair

Candida albicans is an opportunistic human pathogenic fungus affecting millions of people globally; high mortality rates are possible in systemic infection. Filamentation or a filamentous growth pattern is a primary virulence mechanism of C. albicans underlying other virulent behaviour....

Ongoing Study Of The Association Of Apoe Gene Polymorphisms With Cognitive Impairment In The Rio Grande Valley Hispanic Population, Jaime Miguel L. Saveron, Daniela Gamez, Chun Xu

Research Symposium

Background: Alzheimer's disease (AD), a prevalent neurodegenerative disorder, exhibits a significant genetic component. In addition, mild cognitive impairment (MCI) is a key risk factor for AD. While certain demographic factors and genetic variants associated with AD and cognitive impairment have been identified in non-Hispanic populations, limited research exists on this subject within the Hispanic population, particularly in the Rio Grande Valley. This study aims to investigate the relationship between the APOE gene, specifically its ε4 allele, and cognitive impairment in the Hispanic population of the Rio Grande Valley.

Methods: A total of 269 Hispanic subjects, aged 60 and above, with …

Newly Diagnosed Ulcerative Colitis In A Young Hispanic Mexican Female At South Texas: A Case Report, Elimar Gonzalez Morales, Jose Gomez Casanovas, Shreel Patel, Khairiya Haj-Yahya

Research Symposium

Introduction: Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) characterized by recurring episodes of inflammation limited to the mucosal layer of the colon. Traditionally, this disease has been associated mostly with white Americans, however in recent years, an increase incidence has been reported in minorities in the US and around the world. In Hispanic population, cases are frequently underdiagnosed, and literature is scarse. In this case, we present a young patient without past medical history who presented with what appeared to be an infectious gastroenteritis and found to have a severe UC.

Case Presentation: A 22-year old Hispanic …

Nebulization Based Inhalation Nanomedicine For Lung Cancer Treatments, Rahul Tiwari, Meghana Kolli, Neeraj Chauhan, Eswara Naga Hanuma, Vivek Kashyap, Subhash Chauhan, Murali Yallapu

Research Symposium

Background: Lung cancer is reported to have a high incidence rate and first leading cause of cancer-related morbidity and mortality across the world including in the United States. Noninvasive nebulized inhalation is a promising delivery strategy for lung, which can enhance the targeting efficiency and detention time interval of nanoparticles in the lung tissue, thus elevating the therapeutic index of therapeutic agent(s) at lower dosages. The aim of this study is to develop inhalable nanoparticles (INPs) for effective delivery of therapeutic agents in lung cancer cell lines and ex vivo models.

Methods: The inhalation nanoparticles (INPs) were prepared by solvent …

Modes Of Fracture Of Flat Bone: Fracture Direction And Stress, Nolan Wang, Mary K. Holden, Everett Baker, Nathaniel Lerch, Nate Fitch

Seaver College Research And Scholarly Achievement Symposium

This study delineates the application of fractography to discern the multifaceted modes of fracture in flat bones, explicating the interplay between fracture directionality and stress states regarding the viscoelastic nature of bone. Despite the perceived brittleness, bone exhibits toughness, attributed to its intricate structure design and amalgamating properties of solid and viscous materials. This research elucidates the variegated fracture modes inherent to bone's dualistic nature by examining fracture surfaces and identifying fracture markings using stereoscopic microscopy. Our observations across seven bone specimens reveal predominant fracture patterns from top to bottom in six instances, with a singular deviation where the fracture …

Coomassie Brilliant Blue Dye As A Method For Analyzing Fracture Markings In Bone, Abigail Hoffmeister, David Harutunyan, Matthew Aizawa, Everett Baker, Brandon Mendoza, Chase Freeman, Siran Iskanian

Seaver College Research And Scholarly Achievement Symposium

Coomassie Brilliant Blue Dye is a dye commonly used to stain proteins. Because of its ability to adhere to proteins, this research has focused on perfecting a method of dyeing a fractured flat bone in order to most accurately observe and analyze fracture markings within the trabecular layer. Stereoscopic microscopy was the chosen technique of analysis for this research because of its proven effectiveness in glass and ceramic fractography to observe varying depths. In order to most effectively apply stereoscopic microscopy to this research, the following variables were manipulated to maximize color contrast in the trabecular layer in order to …

Network Evaluation Of Influential Sensors: A Proposed Approach, John Mello, Kamryn Kamps

Seaver College Research And Scholarly Achievement Symposium

In 2013, the White House issued Presidential Policy Directive 21 (PPD-21) on Critical Infrastructure Security and Resilience to advance a nationally unified effort to ensure a secure, functioning, and resilient critical infrastructure. In 2017, US Senator Dianne Feinstein expressed her concern that inspections conducted on critical infrastructure may not adequately consider the safety consequences of increasingly extreme weather patterns linked to climate change or considerable seismic hazards. Engineers responded to these opportunities by updating surveillance and monitoring programs designed to capture actual infrastructure behavior during operations. While advances in modern instrumentation and computer technologies make it easier to acquire behavior …

Mathematically Modeling How Trapping Regimes That Target Specific Crayfish Life Stages Impact Removal Efficacy, Rini Pattison

Seaver College Research And Scholarly Achievement Symposium

The red swamp crayfish, Procambarus clarkii, is an invasive species introduced into several streams within the Santa Monica Mountains (SMM) in Southern California. Crayfish predation decimates native aquatic species. Thus, the Mountains Restoration Trust (MRT) and Environmental Restoration Group have worked to remove crayfish through regular trapping in Malibu Creek.

To aid conservation efforts, former SURB students William Milligan and Dev Patel developed mathematical models of crayfish removal efficacy. Milligan created a differential equation model of how crayfish removal affects local newt populations. Patel expanded Milligan’s crayfish model by creating a discrete model of the crayfish life cycle that newly …

Drone Imagery Of Submarine Groundwater Discharge Effects On Coastal Primary Productivity On Coral Reefs In Maunalua Bay, Hawai'i, Lulu Wang, Florybeth Flores La Valle, Grace Kim

Seaver College Research And Scholarly Achievement Symposium

Submarine groundwater discharge (SGD) plays a crucial role in coastal ecosystems, especially coral reefs, by introducing terrestrial nutrients and freshwater, significantly affecting the primary productivity of coastal ecosystems and potentially altering ecological balances. La Valle et al. (2023) emphasized the importance of SGD in nutrient distribution and algal productivity, highlighting the need for comprehensive understanding and management strategies in the face of increasing nutrient runoff due to land use changes due to increased population. To better understand the impact, our experiments utilize remote sensing and data science by using a DJI Mavic 3 Enterprise drone with a thermal imaging camera …

Deep Learning Can Be Used To Classify And Segment Plant Cell Types In Xylem Tissue, Reem Al Dabagh, Benjamin Shin, Sean Wu, Fabien Scalzo, Helen Holmlund, Jessica Lee, Chris Ghim, Samuel Fitzgerald, Marinna Grijalva

Seaver College Research And Scholarly Achievement Symposium

Studies of plant anatomical traits are essential for understanding plant physiological adaptations to stressful environments. For example, shrubs in the chaparral ecosystem of southern California have adapted various xylem anatomical traits that help them survive drought and freezing. Previous studies have shown that xylem conduits with a narrow diameter allows certain chaparral shrub species to survive temperatures as low as -12 C. Other studies have shown that increased cell wall thickness of fibers surrounding xylem vessels improves resistance to water stress-induced embolism formation. Historically, these studies on xylem anatomical traits have relied on hand measurements of cells in light micrographs, …